The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
High fat diet induced obesity model using four strains of mice: Kunming, C57BL/6, BALB/c and ICR
Open accessAbstract
High fat diet (HFD) treated mouse is widely used as experimental animal model for hyperlipidemia and hyperglycemia study. Many factors contribute to establish animal model that meant to simulate high fat and glucose diet induced phenotypes. In the present study, four strains of experiment mouse treated by HFD were used to explore the impact of mouse strain on lipid profile, glucose level, and major inflammation cytokines. HFD fed Kunming and ICR mouse gained significantly higher body weight than control which was not shown by C57BL/6 and BALB/c mouse. All four strains fed by HFD has heavier liver and adipose tissue than control ones. Obvious fat droplets and enlarged adipose cells were observed in obese mouse of four strains. Additionally, obese mouse showed typical response to glucose and insulin load in OGTT and ITT. Serum TC, LDL-c, and TC/HDL-c ratio, but not TG, increased in all four strains. Major inflammatory cytokines and insulin level showed little changes in obese mouse as well (P<0.05) The present study could provide basic information for diet induced obesity developed by four commonly used experimental mouse strains.
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Cites
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Genetic Differences among C57BL/6 Substrains
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Evidence of anti-obesity effects of the pomegranate leaf extract in high-fat diet induced obese mice
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Cited by
Wang, H., Li, S., Cui, Z., Qin, T., Shi, H., Ma, J., Li, L., Yu, G., Jiang, T., & Li, C. (2021) · Malaria Journal · doi:10.1186/s12936-021-03786-z · Cited by 36
Fraile-Ramos, J., Garrit, A., Reig-Vilallonga, J., & Giménez-Llort, L. (2023) · Cells · doi:10.3390/cells12111517 · Cited by 26
Silva-Neto, A. F., Fratelli, C., Pucci, V. G., Boldarine, V. T., Ferreira, Y. A. M., Telles, M. M., Braga, A. R. C., & Oyama, L. M. (2023) · Journal of Functional Foods · doi:10.1016/j.jff.2023.105747 · Cited by 15
Metadata
- Authors
- Li, J., Wu, H., Liu, Y., & Yang, L.
- Venue
- Experimental Animals
- Published
- 2020
- Volume
- 69
- Issue
- 3
- Pages
- 326-335
- ISSN
- 0007-5124 (ISSN-L)
- 1341-1357
- 1881-7122
- OpenAlex
- W3011882788
- Cited by
- 266
- References
- 36
- FWCI
- 21.02
- Type
- journal article
- Language
- en
- Open access
- diamond
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- Li, J., Wu, H., Liu, Y., & Yang, L. (2020). High fat diet induced obesity model using four strains of mice: Kunming, C57BL/6, BALB/c and ICR. Experimental Animals. https://doi.org/10.1538/expanim.19-0148
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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