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The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

The Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infection (PANDAS) Etiology for Tics and Obsessive-Compulsive Symptoms: Hypothesis or Entity? Practical Considerations for the Clinician

Kurlan, Roger, Kaplan, Edward L.·2004·Pediatrics
DOI 10.1542/peds.113.4.883
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Abstract

Clinicians have been faced with much publicity and contradictory scientific evidence regarding a recently described condition termed pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS). It has been proposed that children with PANDAS experience tics, obsessive-compulsive behavior, and perhaps other neuropsychiatric symptoms as an autoimmune response to streptococcal infection. We review current scientific information and conclude that PANDAS remains a yet-unproven hypothesis. Until more definitive scientific proof is forthcoming, there seems to be insufficient evidence to support 1) routine microbiologic or serologic testing for group A streptococcus in children who present with neuropsychiatric symptoms or 2) the clinical use of antibiotic or immune-modifying therapies in such patients. The optimum diagnostic and therapeutic approach awaits the results of additional research studies.

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Research works printed but not linked: 26

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Metadata

Authors
Kurlan, R., & Kaplan, E. L.
Venue
Pediatrics
Publisher
American Academy of Pediatrics (AAP)
Published
2004-04-01
Volume
113
Issue
4
Pages
883-886
ISSN
  • 0031-4005 (ISSN-L)
  • 1098-4275
DOI
10.1542/peds.113.4.883
OpenAlex
W2038448100
Cited by
161
References
4
FWCI
15.74
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infection (PANDAS) Etiology for Tics and Obsessive-Compulsive Symptoms: Hypothesis or Entity? Practical Considerations for the Clinician. https://app.cochat.ai/papers/10.1542/peds.113.4.883
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Kurlan, R., & Kaplan, E. L. (2004). The Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infection (PANDAS) Etiology for Tics and Obsessive-Compulsive Symptoms: Hypothesis or Entity? Practical Considerations for the Clinician. Pediatrics. https://doi.org/10.1542/peds.113.4.883

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