The DOI matches its Crossref record.
A TEST FOR CONCENTRATION OF ELECTROLYTES IN SWEAT IN CYSTIC FIBROSIS OF THE PANCREAS UTILIZING PILOCARPINE BY IONTOPHORESIS
Abstract
A method of performing the test for chloride or sodium in the sweat of patients with cystic fibrosis of the pancreas is presented. It utilizes pilocarpine by iontophoresis and has the advantage of being both rapid and painless. Data are presented to show that the method is reliable.
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In the citing paper
“Sweat testing has historically been used in applications ranging from medical diagnosis of cystic fibrosis and autonomic neuropathy to assessment of fluid and electrolyte balance in endurance athletes (6–10).”
From Regional and correlative sweat analysis using high-throughput microfluidic sensing patches toward decoding sweat (2019) · cites this paper as [6]
In the citing paper
“Sweat behaviors of only a few analytes, including ethanol and chloride, have been extensively investigated and related to blood concentrations or health status (6, 8, 27, 35).”
From Regional and correlative sweat analysis using high-throughput microfluidic sensing patches toward decoding sweat (2019) · cites this paper as [6]
In the citing paper
“During the iontophoresis operation, the cationic pilocarpine drug was delivered across the skin at the anode electrode (Figure 1D).32”
From Noninvasive Alcohol Monitoring Using a Wearable Tattoo-Based Iontophoretic-Biosensing System (2016) · cites this paper as [32]
In the citing paper
“Pilocarpine is a large positively charged molecule, and the electron shuttling activity of PB can be influenced by pilocarpine due to the vulnerability of PB against other positive ions in electrolytes.32”
From Noninvasive Alcohol Monitoring Using a Wearable Tattoo-Based Iontophoretic-Biosensing System (2016) · cites this paper as [32]
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Wearable biosensors for healthcare monitoring
Kim, J., Campbell, A. S., de Ávila, B. E.-F., & Wang, J. (2019) · Nature Biotechnology · doi:10.1038/s41587-019-0045-y · Cited by 3,373
Bio-Integrated Wearable Systems: A Comprehensive Review
Ray, T. R., Choi, J., Bandodkar, A. J., Krishnan, S., Gutruf, P., Tian, L., Ghaffari, R., & Rogers, J. A. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00573 · Cited by 1,350
Farrell, P. M., Rosenstein, B. J., White, T. B., Accurso, F. J., Castellani, C., Cutting, G. R., Durie, P. R., LeGrys, V. A., Massie, J., Parad, R. B., et al. (2008) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2008.05.005 · Cited by 1,093
The future of cystic fibrosis care: a global perspective
Bell, S. C., Mall, M. A., Gutierrez, H., Macek, M., Madge, S. L., Davies, J. C., Burgel, P., Tullis, E., Castaños, C., Castellani, C., et al. (2019) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(19)30337-6 · Cited by 1,081
Mutations of the Cystic Fibrosis Gene in Patients with Chronic Pancreatitis
SHARER, N. H., Schwarz, M. J., Malone, G., Howarth, A., Painter, J. E., Super, M., & Braganza, J. M. (1998) · New England Journal of Medicine · doi:10.1056/nejm199809033391001 · Cited by 945
Metadata
- Authors
- Gibson, L. E., & Cooke, R. E.
- Affiliations
- Johns Hopkins University (US)
- Venue
- Pediatrics
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 1959-03-01
- Volume
- 23
- Issue
- 3
- Pages
- 545-549
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- OpenAlex
- W1946951765
- Cited by
- 1,434
- References
- 0
- Citations by year
- 2026: 17 · 2025: 21 · 2024: 24 · 2023: 24 · 2022: 15 · 2021: 34 · 2020: 41 · 2019: 37 · 2018: 37 · 2017: 42 · 2016: 37 · 2015: 32 · 2014: 35 · 2013: 30 · 2012: 39
- FWCI
- 27.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- PEDIATRICS (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cystic Fibrosis Research Advances
- Health Sciences › Medicine › Surgery › Pancreatitis Pathology and Treatment
- Health Sciences › Medicine › Physiology (medical) › Salivary Gland Disorders and Functions
- Keywords
- cystic fibrosis, sweat test, sweat electrolytes, chloride, sodium, pilocarpine, iontophoresis
- MeSH terms
- Chlorides, Cystic Fibrosis, Electrolytes, Humans, Iontophoresis, Pilocarpine, Sodium, Sodium, Dietary, Sweat
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