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Cited by 54Fibromyalgia and Chronic Fatigue Syndrome ResearchMusculoskeletal pain and rehabilitationLong-Term Effects of COVID-19

Is cognitive behaviour therapy for chronic fatigue syndrome also effective for pain symptoms?

Knoop, Hans, Stulemeijer, Maja, Prins, Judith B., van der Meer, Jos W.M., Bleijenberg, Gijs·2007·Behaviour Research and Therapy
DOI 10.1016/j.brat.2007.03.002
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Abstract

Patients with chronic fatigue syndrome (CFS) frequently report chronic pain symptoms. Cognitive behavioural therapy (CBT) for CFS results in a reduction of fatigue, but is not aimed at pain symptoms. In this study, we tested the hypothesis that a successful treatment of CFS can also lead to a reduction of pain. The second objective was to explore possible mechanisms of changes in pain. The third objective was to assess the predictive value of pain for treatment outcome. Data from two previous CBT studies were used, one of adult CFS patients (n=96) and one of adolescent CFS patients (n=32). Pain severity was assessed with a daily self-observation list at baseline and post-treatment. The location of pain in adults was assessed with the McGill Pain Questionnaire (MPQ). Patients were divided into recovered and non-recovered groups. Recovery was defined as reaching a post-treatment level of fatigue within normal range. Recovered adult and adolescent CFS patients reported a significant reduction of pain severity compared to non-recovered patients. Recovered adult patients also had fewer pain locations following treatment. The decrease in fatigue predicted the change in pain severity. In adult patients, a higher pain severity at baseline was associated with a negative treatment outcome.

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Crossref · 10.1016/j.brat.2007.03.002

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  • A role for pain in explaining response to treatment for CFS has been identified in previous research, with patients experiencing more pain before treatment benefitting less from treatment.

    “A role for pain in explaining response to treatment for CFS has been identified in previous research, with patients experiencing more pain before treatment benefitting less from treatment (Knoop et al., 2007; Cella et al., 2011).”

    From The relationship between improvement in insomnia severity and long-term outcomes in the treatment of chronic fatigue (2018) · cites this paper as Knoop et al., 2007

  • There is evidence that pain, depression, and anxiety complicate the course for patients with CFS.

    “There is, however, evidence that pain, depression, and anxiety complicate the course for patients with CFS (Bentall et al., 2002; Cairns and Hotopf, 2005; Knoop et al., 2007; Kempke et al., 2010; Flo and Chalder, 2014).”

    From The relationship between improvement in insomnia severity and long-term outcomes in the treatment of chronic fatigue (2018) · cites this paper as Knoop et al., 2007

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Authors
Knoop, H., Stulemeijer, M., Prins, J. B., van der Meer, J. W. M., & Bleijenberg, G.
Affiliations
  • Radboud University Medical Center (NL)
  • Radboud University Nijmegen (NL)
Corresponding author
Knoop, Hans
ORCID
Venue
Behaviour Research and Therapy
Publisher
Elsevier BV
Published
2007-09
Volume
45
Issue
9
Pages
2034-2043
ISSN
0005-7967 (ISSN-L)
DOI
10.1016/j.brat.2007.03.002
OpenAlex
W1977045331
Cited by
54
References
31
Citations by year
2025: 1 · 2024: 1 · 2023: 1 · 2021: 1 · 2020: 1 · 2019: 3 · 2018: 2 · 2017: 5 · 2016: 3 · 2015: 3 · 2014: 6 · 2013: 4 · 2012: 8
FWCI
2.62
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Behaviour Research and Therapy (publishedVersion)
  • PubMed (publishedVersion)
  • Radboud Repository (Radboud University) (submittedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
  • Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
  • Health Sciences › Medicine › Neurology › Long-Term Effects of COVID-19
Keywords
chronic fatigue syndrome, cognitive behavioral therapy, chronic pain, pain intensity, pain localization, fatigue recovery, treatment outcome prediction, adolescents, McGill Pain Questionnaire, mechanisms of change
MeSH terms
Adolescent, Adult, Child, Female, Humans, Male, Middle Aged, Motor Activity, Pain, Pain Measurement, Prognosis, Severity of Illness Index, Fatigue Syndrome, Chronic, Cognitive Behavioral Therapy, Treatment Outcome, Pain Management

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