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p53-stabilizing Agent CP-31398 Prevents Growth and Invasion of Urothelial Cancer of the Bladder in Transgenic UPII-SV40T Mice
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“Another study evaluated the efficacy of CP31398 in a transgenic UPII-SV40T mouse model of human transitional cell carcinoma (TCC), and the results showed that mice that received CP31398 suppressed invasive TCC.”
From p53: from understanding its structure to advances in therapeutic targeting (2026) · cites this paper as [319]
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CP-31398, a novel p53-stabilizing agent, induces p53-dependent and p53-independent glioma cell death
Wischhusen, J., Naumann, U., Ohgaki, H., Rastinejad, F., & Weller, M. (2003) · Oncogene · doi:10.1038/sj.onc.1207198 · Cited by 158
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Cited by
Targeting mutant p53 for efficient cancer therapy
Bykov, V. J. N., Eriksson, S. E., Bianchi, J., & Wiman, K. G. (2018) · Nature Reviews Cancer · doi:10.1038/nrc.2017.109 · Cited by 889
p53: from understanding its structure to advances in therapeutic targeting
Wang, W., Liu, X., Liu, H., Abolhassani, H., Yan, H., Zhang, H., & Wang, X. (2026) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02549-5 · Cited by 30
Metadata
- Authors
- Madka, V., Zhang, Y., Li, Q., Mohammed, A., Sindhwani, P., Lightfoot, S., Wu, X.-R., Kopelovich, L., & Rao, C. V.
- Venue
- Neoplasia
- Publisher
- Elsevier BV
- Published
- 2013-08
- Volume
- 15
- Issue
- 8
- Pages
- 966-974
- ISSN
- 1476-5586
- Cited by
- 24
- References
- 2
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- creativecommons.org/licenses/by-nc-nd/3.0/ (vor, 277 d)
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- CoChat. (2026). Citation check: p53-stabilizing Agent CP-31398 Prevents Growth and Invasion of Urothelial Cancer of the Bladder in Transgenic UPII-SV40T Mice. https://app.cochat.ai/papers/10.1593/neo.13704
- The paper
- Madka, V., Zhang, Y., Li, Q., Mohammed, A., Sindhwani, P., Lightfoot, S., Wu, X.-R., Kopelovich, L., & Rao, C. V. (2013). p53-stabilizing Agent CP-31398 Prevents Growth and Invasion of Urothelial Cancer of the Bladder in Transgenic UPII-SV40T Mice. Neoplasia. https://doi.org/10.1593/neo.13704
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