17beta-hydroxysteroid dehydrogenase (HSD)/17-ketosteroid reductase (KSR) family; nomenclature and main characteristics of the 17HSD/KSR enzymes

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Inhibitory effects of fluorine-substituted estrogens on the activity of 17beta-hydroxysteroid dehydrogenases

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Selective Insensitivity of ZR-75-1 Human Breast Cancer Cells to 2-Methoxyestradiol: Evidence for Type II 17β-Hydroxysteroid Dehydrogenase as the Underlying Cause

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Localization of type 1 17beta-hydroxysteroid dehydrogenase mRNA and protein in syncytiotrophoblasts and invasive cytotrophoblasts in the human term villi

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Molecular cloning, modeling, and localization of rat type 10 17β-hydroxysteroid dehydrogenase1Nucleotide sequences of cDNAs of rat and mouse type 10 17β-HSDs have been deposited in the GeneBank™/EBI Data Bank with accession number AF069770 and AF233685, respectively.1

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Testosterone Synthesis, Transport, and Metabolism

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Physiology and Pathology of the Female Reproductive Axis

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Role of Type 10 17ß-Hydroxysteroid Dehydrogenase in the Pathogenesis of Alzheimer’s Disease

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Cellular and Animal Studies: Insights into Pathophysiology and Therapy of PCOS

Indran, I. R., Lee, B. H., & Yong, E. (2016) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2016.03.006 · Cited by 21

Diagnosis of 17β-hydroxysteroid dehydrogenase deficiency

Bertelloni, S., Dati, E., & Hiort, O. (2008) · Expert Review of Endocrinology & Metabolism · doi:10.1586/17446651.4.1.53 · Cited by 21

Metabolic changes in Medaka fish induced by cyanobacterial exposures in mesocosms: an integrative approach combining proteomic and metabolomic analyses

Sotton, B., Paris, A., Manach, S. L., Blond, A., Lacroix, G., Millot, A., Duval, C., Huet, H., Qiao, Q., Labrut, S., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-04423-z · Cited by 21

A human short-chain dehydrogenase/reductase gene: structure, chromosomal localization, tissue expression and subcellular localization of its product

Pellegrini, S., Censini, S., Guidotti, S., Iacopetti, P., Rocchi, M., Bianchi, M. E., Covacci, A., & Gabrielli, F. (2002) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/s0167-4781(01)00323-2 · Cited by 21

Human Chorionic Gonadotropin-Dependent Regulation of 17β-Hydroxysteroid Dehydrogenase Type 4 in Preovulatory Follicles and Its Potential Role in Follicular Luteinization

Brown, K. A., Boerboom, D., Bouchard, N., Doré, M., Lussier, J. G., & Sirois, J. (2004) · Endocrinology · doi:10.1210/en.2003-1715 · Cited by 21

Bioproduction of testosterone from phytosterol by Mycolicibacterium neoaurum strains: “one-pot”, two modes

Tekucheva, D. N., Nikolayeva, V. M., Karpov, M. V., Timakova, T. A., Shutov, A. V., & Donova, M. V. (2022) · Bioresources and Bioprocessing · doi:10.1186/s40643-022-00602-7 · Cited by 20

Identification and mRNA expression of two 17β-hydroxysteroid dehydrogenase genes in the marine mussel Mytilus galloprovincialis following exposure to endocrine disrupting chemicals

Zhang, Y., Wang, Q., Ji, Y., Zhang, Q., Wu, H., Xie, J., & Zhao, J. (2014) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2014.04.027 · Cited by 20

Molecular Cloning of a Novel Type of Rat Cytoplasmic 17β-Hydroxysteroid Dehydrogenase Distinct from the Type 5 Isozyme

Ishikura, S., Matsumoto, K., Sanai, M., Horie, K., Matsunaga, T., Tajima, K., El-Kabbani, O. A. L., & Hara, A. (2006) · The Journal of Biochemistry · doi:10.1093/jb/mvj109 · Cited by 20

Searching for the physiological function of 17β-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus: studies of substrate specificity and expression analysis

Rižner, T. L., Stojan, J., & Adamski, J. (2001) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(00)00424-x · Cited by 20

Human 17β-Hydroxysteroid Dehydrogenase Type 5 is Inhibited by Dietary Flavonoids

Krazeisen, A., Rainer Breitling, A., Möller, G., & Adamski, J. (2002) · Advances in experimental medicine and biology · doi:10.1007/978-1-4757-5235-9_14 · Cited by 20

Evaluation of urinary excretion of androgens conjugated to cysteine in human pregnancy by mass spectrometry

Fabregat, A., Marcos, J., Garrostas, L., Segura, J., Pozo, Ó. J., & Ventura, R. (2013) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2013.01.014 · Cited by 19

17β-Hydroxysteroid dehydrogenase (17β-HSD) in scleractinian corals and zooxanthellae

Blomquist, C. H., Lima, P. H., Tarrant, A. M., Atkinson, M. J., & Atkinson, S. (2006) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2005.12.017 · Cited by 19

Progestins used in endocrine therapy and the implications for the biosynthesis and metabolism of endogenous steroid hormones

Toit, R. L.-D., Storbeck, K., Cartwright, M., Cabral, A., & Africander, D. (2016) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2016.09.004 · Cited by 20

Production aspects of testosterone by microbial biotransformation and future prospects

Sambyal, K., & Singh, R. V. (2020) · Steroids · doi:10.1016/j.steroids.2020.108651 · Cited by 19

Expression of COX-2 and steroid converting enzymes in breast cancer

Gunnarsson, C., Jansson, A., Holmlund, B., Ferraud, L., Nordenskjöld, B. A., Rutqvist, L. E., Skoog, L. K., & Stål, O. (2006) · Oncology Reports · doi:10.3892/or.16.2.219 · Cited by 19

The “street light syndrome”, or how protein taxonomy can bias experimental manipulations

Markov, G. V., Lecointre, G., DEMENEIX, B. A., & Laudet, V. (2008) · BioEssays · doi:10.1002/bies.20730 · Cited by 19

Characterization of 17β-Hydroxysteroid Dehydrogenase Type 7 in Reproductive Tissues of the Marmoset Monkey1

Husen, B., Adamski, J., Brüns, A., Deluca, D., Fuhrmann, K., Möller, G., Schwabe, I., & Einspanier, A. (2003) · Biology of Reproduction · doi:10.1095/biolreprod.102.012476 · Cited by 19

STX2171, a 17β-hydroxysteroid dehydrogenase type 3 inhibitor, is efficacious in vivo in a novel hormone-dependent prostate cancer model

Day, J. M., Foster, P., Tutill, H. J., Schmidlin, F., Sharland, C. M., Hargrave, J. D., Vicker, N., Potter, B. V. L., Reed, M. J., & Purohit, A. (2012) · Endocrine Related Cancer · doi:10.1530/erc-12-0231 · Cited by 18

Mechanisms of estradiol inactivation in primate endometrium

Husen, B., Adamski, J., Rune, G. M., & Einspanier, A. (2001) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(00)00421-4 · Cited by 18

Androsterone 3β-substituted derivatives as inhibitors of type 3 17β-hydroxysteroid dehydrogenase

Ngatcha, B. T., Luu-The, V., & Poirier, D. (2000) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(00)00517-5 · Cited by 17

Hydrohysteroid Dehydrogenases – Biological Role and Clinical Importance – Review

Atanassova, N. N., & Koev, Y. (2012) · InTech eBooks · doi:10.5772/54149 · Cited by 16

Development of hormone-dependent prostate cancer models for the evaluation of inhibitors of 17β-hydroxysteroid dehydrogenase Type 3

Day, J. M., Tutill, H. J., Foster, P., Bailey, H. V., Heaton, W. B., Sharland, C. M., Vicker, N., Potter, B. V. L., Purohit, A., & Reed, M. J. (2008) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2008.08.014 · Cited by 16

Transcriptional regulation of the human type 8 17β-hydroxysteroid dehydrogenase gene by C/EBPβ

Villar, J., Celay, J., Alonso, M. M., Rotinen, M., de Miguel, C., Migliaccio, M., & Encı́o, I. (2007) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2006.12.106 · Cited by 16

Derivatives of pyrimidine, phthalimide and anthranilic acid as inhibitors of human hydroxysteroid dehydrogenase AKR1C1

Brožič, P., Cesar, J., Kovač, A., Davies, M., Johnson, A. P., Fishwick, C. W. G., Rižner, T. L., & Gobec, S. (2008) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2008.10.019 · Cited by 16

Structural basis of the multispecificity demonstrated by 17β-hydroxysteroid dehydrogenase types 1 and 5

Lin, S., Shi, R., Qiu, W., Azzi, A., Zhu, D.-W., Dabbagh, H., & Zhou, M. (2006) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2005.11.035 · Cited by 53

Multifunctionality of human 17β-hydroxysteroid dehydrogenases

Möller, G., & Adamski, J. (2006) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2005.11.031 · Cited by 143

Hydroxysteroid Dehydrogenases/Ketosteroid Reductases ( HSD / KSR )

Ratnam, K., Burczynski, M. E., & Penning, T. M. (2002) · Wiley eBooks · doi:10.1002/0471203076.emm0496

Reductive 17beta-hydroxysteroid dehydrogenase types 1, 5 and 7 involved in hormone-dependent cancers : 3D-structure, function and inhibition

Mazumdar, M. (2010)

17β-Hydroxysteroid dehydrogenases/17-ketosteroid reductases (17HSD/KSRs) in prostate cancer : the role of 17HSD/KSR types 2, 5, and 7 in steroid hormone action and loss of heterozygosity at chromosome region 16q

Härkönen, P. (2005) · Cited by 5