The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Macrophages in Renal Disease
Abstract
Macrophages have heterogeneous phenotypes as they exercise their twofold role in the development and recovery of renal diseases. Some subpopulations of macrophages (M1) have a pathogenic function in renal inflammation, making them a logical target for elimination. Alternatively, M2 macrophage subpopulations resolve inflammation and repair injury, making them a potential therapeutic tool against renal injury. Here, we summarize recent findings regarding macrophage plasticity, and the various strategies for targeting or utilizing macrophages to treat renal disease. We highlight, in particular, the potential of renoprotective M2 macrophages to resolve inflammation and repair the kidney.
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Citations
Cites
Exploring the full spectrum of macrophage activation
Mosser, D. M., & Edwards, J. P. (2008) · Nature Reviews Immunology · doi:10.1038/nri2448 · Cited by 9,144
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
Lumeng, C. N., Bodzin, J. L., & Saltiel, A. R. (2007) · Journal of Clinical Investigation · doi:10.1172/jci29881 · Cited by 4,664
Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice
Bedoret, D., Wallemacq, H., Marichal, T., Desmet, C., Quesada Calvo, F., Henry, E., Closset, R., Dewals, B., Thielen, C., Gustin, P., et al. (2009) · Journal of Clinical Investigation · doi:10.1172/jci39717 · Cited by 399
Cited by
Cellular and molecular mechanisms of renal fibrosis
Liu, Y. (2011) · Nature Reviews Nephrology · doi:10.1038/nrneph.2011.149 · Cited by 1,446
Diabetic nephropathy—emerging epigenetic mechanisms
Kato, M., & Natarajan, R. (2014) · Nature Reviews Nephrology · doi:10.1038/nrneph.2014.116 · Cited by 318
EGFR Signaling Promotes TGFβ-Dependent Renal Fibrosis
Chen, J., Chen, J.-K., Nagai, K., Plieth, D., Tan, M., Lee, T.-C., Threadgill, D. W., Neilson, E. G., & Harris, R. C. (2012) · Journal of the American Society of Nephrology · doi:10.1681/asn.2011070645 · Cited by 285
Characterization of murine macrophages from bone marrow, spleen and peritoneum
Wang, C., Yu, X., Cao, Q., Wang, Y., Zheng, G., Tan, T. K., Zhao, H., Zhao, Y., Wang, Y., & Harris, D. C. (2013) · BMC Immunology · doi:10.1186/1471-2172-14-6 · Cited by 225
Self-citationMitophagy-dependent macrophage reprogramming protects against kidney fibrosis
Bhatia, D., Chung, K.-P., Nakahira, K., Patino, E., Rice, M. C., Torres, L. K., Muthukumar, T., Choi, A. M. K., Akchurin, O. M., & Choi, M. E. (2019) · JCI Insight · doi:10.1172/jci.insight.132826 · Cited by 185
Metadata
- Authors
- Wang, Y., & Harris, D. C. H.
- Venue
- Journal of the American Society of Nephrology
- Published
- 2011-01
- Volume
- 22
- Issue
- 1
- Pages
- 21-27
- ISSN
- 1046-6673 (ISSN-L)
- OpenAlex
- W2104029407
- Cited by
- 247
- References
- 3
- FWCI
- 9.33
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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