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Molecular and clinical features of the TP53 signature gene expression profile in early-stage breast cancer
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“Moreover, they have been associated with chromosomal and genomic instability and have also shown to have potential predictive value for responsiveness to immune checkpoint inhibitors [108].”
From The TP53 tumor suppressor gene: From molecular biology to clinical investigations (2025) · cites this paper as [108]
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TP53 mutations in human cancers: origins, consequences, and clinical use.
Olivier, M., Hollstein, M., & Hainaut, P. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a001008 · Cited by 2,199 · cited 1×
“Because of these findings, a comprehensive p53 functional pathway assay should be established considering these abnormalities [10].”
BackgroundInhibiting the p53–MDM2 interaction: an important target for cancer therapy
Chène, P. (2003) · Nature Reviews Cancer · doi:10.1038/nrc991 · Cited by 765
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Cited by
The TP53 tumor suppressor gene: From molecular biology to clinical investigations
Baliakas, P., & Soussi, T. (2025) · Journal of Internal Medicine · doi:10.1111/joim.20106 · Cited by 50
Metadata
- Authors
- Yamaguchi, S., Takahashi, S., Mogushi, K., Izumi, Y., Nozaki, Y., Nomizu, T., Kakugawa, Y., Ishida, T., Ohuchi, N., Ishioka, C., & Kato, S.
- Affiliations
- Department of Clinical Oncology, Juntendo University Graduated School, Tokyo 113-8421, Japan
- Department of Clinical Oncology, Institute of Development, Aging and Cancer, Tohoku University, Sendai 980-8575, Japan
- Diagnostics and Therapeutics of Intractable Diseases, Intractable Disease Research Center, Juntendo University Graduated School, Tokyo 113-8421, Japan
- Department of Surgery, Hoshi General Hospital, Fukushima 963-8501, Japan
- Department of Breast Oncology, Miyagi Cancer Center Hospital, Natori 981-1293, Japan
- Department of Breast and Endocrine Surgical Oncology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan
- Venue
- Oncotarget
- Publisher
- Impact Journals, LLC
- Published
- 2018-02-08
- Volume
- 9
- Issue
- 18
- Pages
- 14193-14206
- ISSN
- 1949-2553
- Cited by
- 15
- References
- 2
- Language
- en
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- Yamaguchi, S., Takahashi, S., Mogushi, K., Izumi, Y., Nozaki, Y., Nomizu, T., Kakugawa, Y., Ishida, T., Ohuchi, N., Ishioka, C., & Kato, S. (2018). Molecular and clinical features of the TP53 signature gene expression profile in early-stage breast cancer. Oncotarget. https://doi.org/10.18632/oncotarget.24447
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.