Beyond recreational physical activity: Examining occupational and household activity, transportation activity, and sedentary behavior in relation to postmenopausal breast cancer risk
Open accessAbstract
OBJECTIVES: We prospectively examined nonrecreational physical activity and sedentary behavior in relation to breast cancer risk among 97 039 postmenopausal women in the National Institutes of Health-AARP Diet and Health Study. METHODS: We identified 2866 invasive and 570 in situ breast cancer cases recorded between 1996 and 2003 and used Cox proportional hazards regression to estimate multivariate relative risks (RRs) and 95% confidence intervals (CIs). RESULTS: Routine activity during the day at work or at home that included heavy lifting or carrying versus mostly sitting was associated with reduced risk of invasive breast cancer (RR = 0.62; 95% CI = 0.42, 0.91; P(trend) = .024). CONCLUSIONS: Routine activity during the day at work or home may be related to reduced invasive breast cancer risk. Domains outside of recreation time may be attractive targets for increasing physical activity and reducing sedentary behavior among postmenopausal women.
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George et al. reported that 7.9% of females sat all day.
“This is comparable to 7.9% of females reported “sitting all day” reported by George et al. [31].”
From Prevalence of Sedentary Behavior in Older Adults: A Systematic Review (2013) · cites this paper as [31]
Significant independent association between sitting time and invasive breast cancer risk and risk of renal cell carcinoma was not shown, although a weak correlation could not be ruled out.
“However, association between sitting time and invasive breast cancer risk and risk of renal cell carcinoma has been specifically examined and significant independent association was not shown, although a weak correlation could not be ruled out [31,32].”
From Prevalence of Sedentary Behavior in Older Adults: A Systematic Review (2013) · cites this paper as [31]
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Prevalence of Sedentary Behavior in Older Adults: A Systematic Review
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“In addition, George et al. (2010) [29] reports—Activity in a routine day, with one sedentary response of “sitting all day”.”
BackgroundInfluentialGeorge, S. M., Moore, S. C., Chow, W.-H., Schatzkin, A., Hollenbeck, A. R., & Matthews, C. E. (2011) · Annals of Epidemiology · doi:10.1016/j.annepidem.2011.04.012 · Cited by 28 · see citing works
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- Authors
- George, S. M., Irwin, M. L., Matthews, C. E., Mayne, S. T., Gail, M. H., Moore, S. C., Albanes, D., Ballard-Barbash, R., Hollenbeck, A. R., Schatzkin, A., & Leitzmann, M. F.
- Affiliations
- National Cancer Institute (US)
- AARP (US)
- ORCID
- Venue
- American Journal of Public Health
- Publisher
- American Public Health Association
- Published
- 2010-11
- Volume
- 100
- Issue
- 11
- Pages
- 2288-2295
- ISSN
- 0090-0036 (ISSN-L)
- 1541-0048
- PMC
- PMC2951936
- OpenAlex
- W2032064308
- Cited by
- 85
- References
- 55
- Citations by year
- 2025: 2 · 2024: 3 · 2023: 6 · 2022: 3 · 2021: 8 · 2020: 5 · 2019: 4 · 2018: 3 · 2017: 6 · 2016: 2 · 2015: 10 · 2014: 6 · 2013: 8 · 2012: 12
- FWCI
- 4.27
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Journal of Public Health (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- University of Regensburg Publication Server (University of Regensburg) (acceptedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Funders
- Pennsylvania Department of Health
- Florida Department of Health
- National Institutes of Health
- National Cancer Institute (T32CA105666)
- Topics
- Health Sciences › Medicine › Oncology › Cancer Risks and Factors
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Oncology › Global Cancer Incidence and Screening
- Keywords
- postmenopausal breast cancer, occupational physical activity, household physical activity, sedentary behavior, heavy lifting, transportation activity, breast cancer risk, postmenopausal women
- MeSH terms
- Age Factors, Breast Neoplasms, Family Characteristics, Female, Humans, Middle Aged, Motor Activity, Recreation, Risk, Risk Factors, Time Factors, Transportation, United States, Exercise, Confidence Intervals, Proportional Hazards Models, Workplace, Postmenopause, Sedentary Behavior
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