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Food Sources of Saturated Fat and the Association With Mortality: A Meta-Analysis
Open accessAbstract
We summarized the data related to foods high in saturated fat and risk of mortality. We searched Cochrane Library, MEDLINE, EMBASE, and ProQuest for studies from January 1952 to May 2012. We identified 26 publications with individual dietary data and all-cause, total cancer, or cardiovascular mortality as endpoints. Pooled relative risk estimates demonstrated that high intakes of milk, cheese, yogurt, and butter were not associated with a significantly increased risk of mortality compared with low intakes. High intakes of meat and processed meat were significantly associated with an increased risk of mortality but were associated with a decreased risk in a subanalysis of Asian studies. The overall quality of studies was variable. Associations varied by food group and population. This may be because of factors outside saturated fat content of individual foods. There is an ongoing need for improvement in assessment tools and methods that investigate food sources of saturated fat and mortality to inform dietary guidelines.
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“Butter consumption is also not significantly associated with incident CHD,223 stroke,222 or total mortality58 (Figure 6).”
From Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review (2016) · cites this paper as [58]
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“In another meta-analysis by O’Sullivan et al.((13)), some studies included white meat in the category of total meat.”
Metadata
- Authors
- O’Sullivan, T. A., Hafekost, K., Mitrou, F., & Lawrence, D.
- Affiliations
- Edith Cowan University (AU)
- Venue
- American Journal of Public Health
- Publisher
- American Public Health Association
- Published
- 2013-09
- Volume
- 103
- Issue
- 9
- Pages
- e31-e42
- ISSN
- 0090-0036 (ISSN-L)
- 1541-0048
- PMC
- PMC3966685
- OpenAlex
- W2113368413
- Cited by
- 168
- References
- 58
- Citations by year
- 2026: 5 · 2025: 7 · 2024: 8 · 2023: 10 · 2022: 18 · 2021: 16 · 2020: 14 · 2019: 20 · 2018: 13 · 2017: 12 · 2016: 21 · 2015: 16 · 2014: 7
- FWCI
- 2.10
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Journal of Public Health (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- UWA Profiles and Research Repository (UWA) (submittedVersion)
- Research Online (Edith Cowan University) (submittedVersion)
- Funders
- Dairy Innovation Australia Limited
- National Health and Medical Research Council
- National Medical Research Council
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
- Keywords
- saturated fat, mortality, all-cause mortality, cancer mortality, cardiovascular mortality, dairy products, milk, cheese, yogurt, butter, meat consumption, processed meat, dietary assessment, dietary guidelines
- MeSH terms
- Dairy Products, Dietary Fats, Food, Food Analysis, Humans, Mortality, Risk Factors
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