Cited by 168Nutritional Studies and DietFatty Acid Research and HealthDiet, Metabolism, and Disease

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Food Sources of Saturated Fat and the Association With Mortality: A Meta-Analysis

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O’Sullivan, Therese A., Hafekost, Katherine, Mitrou, Francis, Lawrence, David·2013·American Journal of Public Health

DOI 10.2105/ajph.2013.301492PMC PMC3966685

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Abstract

We summarized the data related to foods high in saturated fat and risk of mortality. We searched Cochrane Library, MEDLINE, EMBASE, and ProQuest for studies from January 1952 to May 2012. We identified 26 publications with individual dietary data and all-cause, total cancer, or cardiovascular mortality as endpoints. Pooled relative risk estimates demonstrated that high intakes of milk, cheese, yogurt, and butter were not associated with a significantly increased risk of mortality compared with low intakes. High intakes of meat and processed meat were significantly associated with an increased risk of mortality but were associated with a decreased risk in a subanalysis of Asian studies. The overall quality of studies was variable. Associations varied by food group and population. This may be because of factors outside saturated fat content of individual foods. There is an ongoing need for improvement in assessment tools and methods that investigate food sources of saturated fat and mortality to inform dietary guidelines.

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Authors: O’Sullivan, T. A., Hafekost, K., Mitrou, F., & Lawrence, D.
Affiliations: Edith Cowan University (AU)
ORCID: O’Sullivan, Therese A.
Hafekost, Katherine
Mitrou, Francis
Lawrence, David
Venue: American Journal of Public Health
Publisher: American Public Health Association
Published: 2013-09
Volume: 103
Issue: 9
Pages: e31-e42
ISSN: 0090-0036 (ISSN-L)
1541-0048
DOI: 10.2105/ajph.2013.301492
PMC: PMC3966685
OpenAlex: W2113368413
Cited by: 168
References: 58
Citations by year: 2026: 5 · 2025: 7 · 2024: 8 · 2023: 10 · 2022: 18 · 2021: 16 · 2020: 14 · 2019: 20 · 2018: 13 · 2017: 12 · 2016: 21 · 2015: 16 · 2014: 7
FWCI: 2.10
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: American Journal of Public Health (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
UWA Profiles and Research Repository (UWA) (submittedVersion)
Research Online (Edith Cowan University) (submittedVersion)
Funders: Dairy Innovation Australia Limited
National Health and Medical Research Council
National Medical Research Council
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
Keywords: saturated fat, mortality, all-cause mortality, cancer mortality, cardiovascular mortality, dairy products, milk, cheese, yogurt, butter, meat consumption, processed meat, dietary assessment, dietary guidelines
MeSH terms: Dairy Products, Dietary Fats, Food, Food Analysis, Humans, Mortality, Risk Factors

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Food Sources of Saturated Fat and the Association With Mortality: A Meta-Analysis

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