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PreprintCited by 26Mindfulness and Compassion InterventionsBlood Pressure and Hypertension StudiesCardiac Health and Mental Health

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Mindfulness-based intervention for hypertension patients with depression and/or anxiety in the community: a randomized controlled trial

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Fan, Jingchun, Zhang, Hailiang, Guo, Jiaohong, Zhang, Xiangrong, Jiang, Xiaomei, Dai, Runjing, Zhao, Na, Pan, Weimin, Bao, Shisan·2024·Trials
DOI 10.21203/rs.3.rs-3294527/v1PMC PMC11529483

Preprint — published as 10.1186/s13063-024-08139-0 · Paper page

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Abstract

Objective To evaluate mindfulness-based intervention for hypertension with depression and/or anxiety. Methods A 10-week mindfulness-based intervention, including health education about hypertension, which only for control group, was applied to intervention group to sooth sixty hypertension patients with depression/anxiety. Patients Health Questionnaire 9-items (PHQ-9) and the Generalized Anxiety Disorder scale-7 items (GAD-7) were used to assess severity of depressive and/or anxiety; in conjunction with blood pressure (BP) measured twice daily. The study used the self-made self-efficacy scale and awareness of physical and mental health to evaluate the mental health and state. Results The depression PHQ-9 or GAD-7 scores reduced by 21.1% or 17.8% in the mindfulness-based intervention group, compared to the control (Z=-2.040, P = 0.041) post 10 week period, suggesting significant reduced anxiety/stress. These results were consistent with reduction of systolic BP of 12.24 mm Hg (t = 6.041, P = 0.000). The self-efficacy score of the mindfulness intervention group was significantly improved compared to the control (t = 7.818, P < 0.001), while the awareness rate of physical and mental health of the mindfulness intervention group was significantly improved compared to the control (χ2 = 5.781, P = 0.016). Conclusion Mindfulness-based intervention reduces the severity of depression and/or anxiety, improves BP in hypertensive patients, as well as, improved self-efficacy score. Trial registration Chinese Clinical Trial Registry, ChiCTR1900028258. Registered 16 December 2019, https://www.chictr.org.cn/showproj.html?proj=43627.

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Metadata

Authors
Fan, J., Zhang, H., Guo, J., Zhang, X., Jiang, X., Dai, R., Zhao, N., Pan, W., & Bao, S.
Affiliations
  • Gansu University of Traditional Chinese Medicine (CN)
  • Pingliang People's Hospital (CN)
  • Center of Hekou Town
  • Gansu Gem Flower Hospital
  • Gansu Provincial Center for Disease Control and Prevention (CN)
Corresponding author
  • Fan, Jingchun
  • Guo, Jiaohong
  • Bao, Shisan
ORCID
Venue
Trials
Publisher
Springer Science and Business Media LLC
Published
2024-02-06
Volume
25
Issue
1
Pages
299-299
ISSN
1745-6215 (ISSN-L)
DOI
10.21203/rs.3.rs-3294527/v1
PMC
PMC11529483
OpenAlex
W4396597537
Cited by
26
References
1
Citations by year
2026: 14 · 2025: 11 · 2024: 1
FWCI
12.99
Type
journal article
Language
en
Open access
Licence
Locations
  • Trials (publishedVersion, cc-by)
  • Research Square (acceptedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Gansu University of Chinese Medicine
Topics
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Keywords
mindfulness-based interventions, hypertension, depression, anxiety, blood pressure reduction, self-efficacy, health awareness, community-based intervention, PHQ-9, GAD-7
MeSH terms
Aged, Anxiety, Blood Pressure, Depression, Female, Humans, Hypertension, Male, Mental Health, Middle Aged, Time Factors, Treatment Outcome, Self Efficacy, Mindfulness

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