Cited by 126Patient Safety and Medication ErrorsElectronic Health Records SystemsPharmaceutical Practices and Patient Outcomes

Potential benefits and problems with computerized prescriber order entry: Analysis of a voluntary medication error-reporting database

Zhan, Chunliu, Hicks, Rodney W., Blanchette, Christopher M., Keyes, Margaret A., Cousins, Diane D.·2006·American Journal of Health-System Pharmacy

Abstract

PURPOSE: The potential benefits and problems associated with computerized prescriber-order-entry (CPOE) systems were studied. METHODS: A national voluntary medication error-reporting database, Medmarx, was used to compare facilities that had CPOE with those that did not have CPOE. The characteristics of medication errors reportedly caused by CPOE were explored, and the text descriptions of these errors were qualitatively analyzed. RESULTS: Facilities with CPOE reported fewer inpatient medication errors and more outpatient medication errors than facilities without CPOE, but the statistical significance of these differences could not be determined. Facilities with CPOE less frequently reported medication errors that reached patients (p < 0.01) or harmed patients (p < 0.01). More than 7000 CPOE-related medication errors were reported over seven months in 2003, and about 0.1% of them resulted in harm or adverse events. The most common CPOE errors were dosing errors (i.e., wrong dose, wrong dosage form, or extra dose). Both quantitative and qualitative analyses indicate that CPOE could lead to medication errors not only because of faulty computer interface, mis-communication with other systems, and lack of adequate decision support but also because of common human errors such as knowledge deficit, distractions, inexperience, and typing errors. CONCLUSION: A national, voluntary medication error-reporting database cannot be used to determine the effectiveness of a CPOE system in reducing medication errors because of the variability in the number of reports from different institutions. However, it may provide valuable information on the specific types of errors related to CPOE systems.

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Crossref · 10.2146/ajhp050379

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Authors
Zhan, C., Hicks, R. W., Blanchette, C. M., Keyes, M. A., & Cousins, D. D.
Affiliations
  • Agency for Healthcare Research and Quality (US)
  • United States Pharmacopeial Convention (US)
  • University of Maryland, Baltimore (US)
  • Universidad San Pedro (PE)
Corresponding author
Zhan, Chunliu
Venue
American Journal of Health-System Pharmacy
Published
2006-02-15
Volume
63
Issue
4
Pages
353-358
ISSN
  • 1079-2082 (ISSN-L)
  • 1535-2900
OpenAlex
W2095509663
Cited by
126
References
16
Citations by year
2025: 1 · 2024: 2 · 2023: 1 · 2022: 1 · 2021: 1 · 2020: 4 · 2019: 5 · 2018: 1 · 2017: 11 · 2016: 10 · 2015: 5 · 2014: 5 · 2013: 11 · 2012: 11
FWCI
16.76
Type
journal article
Language
en
Open access
closed
Locations
  • American Journal of Health-System Pharmacy (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Health Professions › Emergency Medical Services › Patient Safety and Medication Errors
  • Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
  • Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
Keywords
computerized physician order entry, medication errors, medication error reporting, dosing errors, clinical decision support, human error, patient harm
MeSH terms
Computers, Humans, Medication Errors, Medication Systems, Drug Prescriptions, Databases as Topic, Medical Order Entry Systems

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