The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
Leptin resistance: underlying mechanisms and diagnosis
Open accessAbstract
Leptin and its receptors have been identified as key regulators of body weight and energy homeostasis. A decrease in tissue sensitivity to leptin leads to the development of obesity and metabolic disorders, such as insulin resistance and dyslipidemia. Mechanisms underlying the development of leptin resistance include mutations in the genes encoding leptin and its receptors, as well as proteins involved in self-regulation of leptin synthesis and blood-brain barrier permeability. Leptin resistance encompasses a complex pathophysiological phenomenon with a number of potential research lines. In this review, we analyze the existing data on the methods used to diagnose leptin resistance.
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Cites
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Leptin Inhibits Bone Formation through a Hypothalamic Relay
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The weight of leptin in immunity
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Cited by
Obesity as a Risk Factor for Dementia and Alzheimer’s Disease: The Role of Leptin
Flores-Cordero, J. A., Pérez-Pérez, A., Jiménez-Cortegana, C., Alba, G., Flores-Barragán, A., & Sánchez-Margalet, V. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23095202 · Cited by 212
The Burden of Antipsychotic-Induced Weight Gain and Metabolic Syndrome in Children
Libowitz, M. R., & Nurmi, E. L. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.623681 · Cited by 99
Jung, J., Lee, S. M., Lee, M.-J., Ryu, J.-S., Song, J.-H., Lee, J.-E., Kang, G., Kwon, O. S., & Park, J.-Y. (2021) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2021.02.003 · Cited by 84
Dysregulated resting state functional connectivity and obesity: A systematic review
Syan, S. K., McIntyre-Wood, C., Minuzzi, L., Hall, G., McCabe, R. E., & MacKillop, J. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.08.019 · Cited by 66
Zinc homeostasis and redox alterations in obesity
Franco, C., & Canzoniero, L. M. T. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1273177 · Cited by 31
Metadata
- Authors
- Gruzdeva, O., Borodkina, D., Uchasova, E., Dyleva, Y., & Barbarash, O.
- Venue
- Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
- Publisher
- Informa UK Limited
- Published
- 2019-01
- Volume
- Volume 12
- Pages
- 191-198
- ISSN
- 1178-7007 (ISSN-L)
- OpenAlex
- W2913232622
- Cited by
- 299
- References
- 84
- FWCI
- 17.09
- Type
- journal article
- Language
- en
- Open access
- gold
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- CoChat. (2026). Citation check: Leptin resistance: underlying mechanisms and diagnosis. https://app.cochat.ai/papers/10.2147/dmso.s182406
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- Gruzdeva, O., Borodkina, D., Uchasova, E., Dyleva, Y., & Barbarash, O. (2019). Leptin resistance: underlying mechanisms and diagnosis. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. https://doi.org/10.2147/dmso.s182406
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
