The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Inhalation drug delivery devices: technology update
Open accessAbstract
The pulmonary route of administration has proven to be effective in local and systemic delivery of miscellaneous drugs and biopharmaceuticals to treat pulmonary and non-pulmonary diseases. A successful pulmonary administration requires a harmonic interaction between the drug formulation, the inhaler device, and the patient. However, the biggest single problem that accounts for the lack of desired effect or adverse outcomes is the incorrect use of the device due to lack of training in how to use the device or how to coordinate actuation and aerosol inhalation. This review summarizes the structural and mechanical features of aerosol delivery devices with respect to mechanisms of aerosol generation, their use with different formulations, and their advantages and limitations. A technological update of the current state-of-the-art designs proposed to overcome current challenges of existing devices is also provided.
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Cites
Update on Key Emerging Challenges in Cystic Fibrosis
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What the pulmonary specialist should know about the new inhalation therapies
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Particle Engineering for Pulmonary Drug Delivery
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Metadata
- Authors
- Garcia-Contreras, L., Ibrahim, M., & Verma, R.
- Venue
- Medical Devices: Evidence and Research
- Publisher
- Informa UK Limited
- Published
- 2015-02
- Volume
- 8
- Pages
- 131
- ISSN
- 1179-1470 (ISSN-L)
- OpenAlex
- W2018698029
- Cited by
- 306
- References
- 37
- FWCI
- 14.75
- Type
- journal article
- Language
- en
- Open access
- gold
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