Sex Differences in Pharmacokinetics and Pharmacodynamics

Goodman & Gilman's The Pharmacological Basis of Therapeutics

Brunton, L. L. (1985) · Cited by 7,321

Goodman and Gilman's the Pharmacological Basis of Therapeutics

Stigelman, W. H., & Pharm, D. (1986) · Military Medicine · doi:10.1093/milmed/151.1.386 · Cited by 6,796

High Blood Alcohol Levels in Women: The Role of Decreased Gastric Alcohol Dehydrogenase Activity and First-Pass Metabolism

Frezza, M., di Padova, C., Pozzato, G., Terpin, M., Baraona, E., & Lieber, C. S. (1990) · New England Journal of Medicine · doi:10.1056/nejm199001113220205 · Cited by 1,328

Sex-Based Differences in the Effect of Digoxin for the Treatment of Heart Failure

Rathore, S. S., Wang, Y., & Krumholz, H. M. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa021266 · Cited by 688

Exploring the Biological Contributions to Human Health

Institute of Medicine (2001) · National Academies Press eBooks · doi:10.17226/10028 · Cited by 658

Gender Differences in Pharmacokinetics of Alcohol

Baraona, E., Abittan, C. S., Dohmen, K., Moretti, M., Pozzato, G., Chayes, Z. W., Schaefer, C., & Lieber, C. S. (2001) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2001.tb02242.x · Cited by 583

Sex Differences in Pharmacokinetics and Pharmacodynamics

Gandhi, M., Aweeka, F. T., Greenblatt, R. M., & Blaschke, T. F. (2004) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.44.101802.121453 · Cited by 546

Olanzapine

Callaghan, J. T., Bergstrom, R. F., Ptak, L. R., & Beasley, C. M. (1999) · Clinical Pharmacokinetics · doi:10.2165/00003088-199937030-00001 · Cited by 544

Predicting drug disposition, absorption/elimination/transporter interplay and the role of food on drug absorption

Custodio, J. M., Wu, C., & Benet, L. Z. (2007) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.08.043 · Cited by 436

Effect of age and gender on the activity of human hepatic CYP3A

Hunt, C. M., Westerkam, W. R., & Stave, G. M. (1992) · Biochemical Pharmacology · doi:10.1016/0006-2952(92)90010-g · Cited by 426

Iron deficiency and iron deficiency anaemia in women of reproductive age: Sex- and gender-based risk factors and inequities

Burns, J. L., Miller, C. H., Fontaine‐Bisson, B., & Connor, K. L. (2025) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2025.127684 · Cited by 25

One in 10 Virally Suppressed Persons With HIV in The Netherlands Experiences ≥10% Weight Gain After Switching to Tenofovir Alafenamide and/or Integrase Strand Transfer Inhibitor

Verburgh, M. L., Wit, F. W. N. M., Boyd, A. C., Verboeket, S. O., Reiss, P., & van der Valk, M. (2022) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofac291 · Cited by 25

Sex-specific effects of psychoactive pollution on behavioral individuality and plasticity in fish

Polverino, G., Aich, U., Brand, J. A., Bertram, M. G., Martin, J. M., Tan, H., Soman, V. R., Mason, R. T., & Wong, B. B. M. (2023) · Behavioral Ecology · doi:10.1093/beheco/arad065 · Cited by 25

Sex differences in lipid peroxidation and fatty acid levels in recent onset schizophrenia

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Female Sex and Mortality in Patients with Staphylococcus aureus Bacteremia

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Effect of Gender and Age on the Relative Bioavailability of Doravirine: Results of a Phase I Trial in Healthy Subjects

Behm, M. O., Yee, K. L., Li, F., & Fackler, P. H. (2016) · Antiviral Therapy · doi:10.3851/imp3142 · Cited by 24

Pharmacokinetic studies in pregnancy

Avram, M. J. (2020) · Seminars in Perinatology · doi:10.1016/j.semperi.2020.151227 · Cited by 24

Effect of ageing on antiretroviral drug pharmacokinetics using clinical data combined with modelling and simulation

Stader, F., Courlet, P., Kinvig, H., Battegay, M., Decosterd, L. A., Penny, M. A., Siccardi, M., & Marzolini, C. (2020) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.14402 · Cited by 24

Superior Efficacy of a Bedaquiline, Delamanid, and Linezolid Combination Regimen in a Mouse Tuberculosis Model

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Population pharmacokinetic analysis of ulotaront in subjects with schizophrenia

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The Person’s Care Requires a Sex and Gender Approach

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Population pharmacokinetics analyses of rifampicin in adult and children populations: A systematic review

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Harnessing Clinical Trial and Real-World Data Towards an Understanding of Sex Effects on Drug Pharmacokinetics, Pharmacodynamics and Efficacy

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Sex-specific interventions to prevent and manage frailty

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Environmental pesticide exposure and Alzheimer's disease in southern Spain: A cross-sectional study

Ruiz‐González, C., Román, P., Rueda‐Ruzafa, L., Cardona, D., Requena, M., & Alarcón, R. (2024) · Psychiatry Research · doi:10.1016/j.psychres.2024.115932 · Cited by 26

Introduction to Therapeutic Drug Monitoring

Dasgupta, A. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-385467-4.00001-4 · Cited by 24

No differences between men and women in adverse drug reactions related to psychotropic drugs: a survey from F rance, I taly and S pain

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Sex and estrous cycle influence diazepam effects on anxiety and memory: Possible role of progesterone

Silva, A. F., Sousa, D. S., Medeiros, A. M., Macêdo, P. T., Leão, A. H. F. F., Ribeiro, A. M., Izídio, G. S., & Silva, R. H. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.05.003 · Cited by 25

Gender differences in the adverse events’ profile registered in seven observational studies of a wide gender-medicine (MetaGeM) project: the MetaGeM safety analysis

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Sex Differences in Psychiatric Hospitalizations of Individuals With Psychotic Disorders

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Experimental versus theoretical log D7.4, pKa and plasma protein binding values for benzodiazepines appearing as new psychoactive substances

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Isoniazid Concentration and NAT2 Genotype Predict Risk of Systemic Drug Reactions during 3HP for LTBI

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Cardioprotective Effects of Dietary Phytochemicals on Oxidative Stress in Heart Failure by a Sex-Gender-Oriented Point of View

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A memory-improving dipeptide, Tyr-Pro, can reach the mouse brain after oral administration

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Short‐Term Risk of Bleeding During Heparin Bridging at Initiation of Vitamin K Antagonist Therapy in More Than 90 000 Patients With Nonvalvular Atrial Fibrillation Managed in Outpatient Care

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Sex-related susceptibility in coronavirus disease 2019 (COVID-19): Proposed mechanisms

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Sex differences in ketamine's therapeutic effects for mood disorders: A systematic review

Benitah, K. C., Siegel, A. N., Lipsitz, O., Rodrigues, N. B., Meshkat, S., Lee, Y. L., Mansur, R. B., Nasri, F., Lui, L. M. W., McIntyre, R. S., et al. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114579 · Cited by 24

Gender-affirming estrogen therapy route of administration and cardiovascular risk: a systematic review and narrative synthesis

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Pharmacogenomics and health disparities, are we helping?

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Doxorubicin Dose-Dependent Impact on Physiological Balance—A Holistic Approach in a Rat Model

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Sex-Related Differences in Chronic Pain: A Narrative Review by a Multidisciplinary Task Force

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Safety of Outpatient Parenteral Antimicrobial Therapy in Children

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Mercury Contamination of Cattle in Artisanal and Small-Scale Gold Mining in Bombana, Southeast Sulawesi, Indonesia

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An Up-to-Date Article Regarding Particularities of Drug Treatment in Patients with Chronic Heart Failure

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Compound combinations targeting longevity: Challenges and perspectives

Rybina, O. Y., Symonenko, A. V., & PASYUKOVA, E. G. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.101851 · Cited by 23

Sex difference in alcohol withdrawal syndrome: a scoping review of clinical studies

Unlu, H., Macaron, M. M., Taner, H. A., Kaba, D., Sarı, B. A., Schneekloth, T. D., Leggio, L., & Abulseoud, O. A. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1266424 · Cited by 22

Sex Differences in the Pituitary Transforming Growth Factor-β1 System: Studies in a Model of Resistant Prolactinomas

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Genetic Variations in ABCB1 and CYP3A5 as well as Sex Influence Quinine Disposition Among Ugandans

Mukonzo, J., Waako, P. J., Ogwal-Okeng, J. W., Gustafsson, L. L., & Aklillu, E. (2010) · Therapeutic Drug Monitoring · doi:10.1097/ftd.0b013e3181da79d6 · Cited by 22

An oral formulation of efavirenz‐loaded lactoferrin nanoparticles with improved biodistribution and pharmacokinetic profile

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Measuring and reporting treatment adherence: What can we learn by comparing two respiratory conditions?

Tibble, H., Flook, M., Sheikh, A., Tsanas, A., Horne, R., Vrijens, B., Geest, S. D., & Stagg, H. R. (2020) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.14458 · Cited by 22

Trends and risk factors in severe hypoglycemia among individuals with type 2 diabetes in Korea

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Safety considerations surrounding use of treatment options for nausea and vomiting in pregnancy

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Activation of Glutamate Transporter-1 (GLT-1) Confers Sex-Dependent Neuroprotection in Brain Ischemia

Tejeda-Bayron, F. A., Rivera-Aponte, D. E., Malpica-Nieves, C. J., Maldonado-Martínez, G., Maldonado, H. M., Skatchkov, S. N., & Eaton, M. J. (2021) · Brain Sciences · doi:10.3390/brainsci11010076 · Cited by 23

Sex Proportionality in Pre-clinical and Clinical Trials: An Evaluation of 22 Marketing Authorization Application Dossiers Submitted to the European Medicines Agency

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Impact of age and gender on the efficacy and safety of upfront therapy with panitumumab plus FOLFOX followed by panitumumab-based maintenance: a pre-specified subgroup analysis of the Valentino study

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Perinatal Psychoactive Substances Use: A Rising Perinatal Mental Health Concern

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Sex and gender differences in health-related quality of life in individuals treated with incremental and conventional hemodialysis

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CYP2B6*6 and CYP2B6*18 Predict Long-Term Efavirenz Exposure Measured in Hair Samples in HIV-Positive South African Women

Röhrich, C. R., Drögemöller, B. I., Ikediobi, O. N., van der Merwe, L., Grobbelaar, N., Wright, G. E. B., McGregor, N. W., & Warnich, L. (2015) · AIDS Research and Human Retroviruses · doi:10.1089/aid.2015.0048 · Cited by 21

Sex Differences in Type-2 Diabetes: Implications for Cardiovascular Risk Management

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Retrospective study of reported adverse events due to complementary health products in Singapore from 2010 to 2016

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Hepatic Transcript Profiles of Cytochrome P450 Genes Predict Sex Differences in Drug Metabolism

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Population Pharmacokinetics of Caspofungin among Extracorporeal Membrane Oxygenation Patients during the Postoperative Period of Lung Transplantation

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Sex disparities in the current era of pediatric heart transplantation in the United States

Bhimani, S. A., Hsich, E., Boyle, G., Liu, W., Worley, S. E., Bostdorff, H., Nasman, C., Saarel, E. V., & Amdani, S. M. (2021) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2021.10.021 · Cited by 21

How much 'enrichment' is enough for laboratory rodents? A systematic review and meta-analysis re-assessing the impact of well-resourced cages on morbidity and mortality

Cait, J., Winder, C. B., & Mason, G. J. (2024) · Applied Animal Behaviour Science · doi:10.1016/j.applanim.2024.106361 · Cited by 21

HFpEF and sex: understanding the role of sex differences

Smereka, Y., & Ezekowitz, J. A. (2024) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2023-0403 · Cited by 24

Sex Differences in Kidney Health and Disease

Harvey, B. J., & de la Rosa, D. Á. (2024) · The Nephron journals/Nephron journals · doi:10.1159/000541352 · Cited by 20

Consensus Guidelines for Therapeutic Drug Monitoring in Neuropsychopharmacology: Update 2026 – Pharmacokinetic, pharmacogenetic and clinical aspects

Hart, X. M., Gründer, G., Unterecker, S., Schoretsanitis, G., Hiemke, C., Adamovic, I., Amann, F., Baumann, P., Bergemann, N., Brandt, C., et al. (2026) · Pharmacopsychiatry · doi:10.1055/a-2860-7861 · Cited by 20

Differences in medical treatment and clinical characteristics between men and women with heart failure – a single-centre multivariable analysis

Norberg, H., Pranic, V., Bergdahl, E., & Lindmark, K. (2020) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-019-02782-2 · Cited by 20

Impact of sex-specific target dose in chronic heart failure patients with reduced ejection fraction

Veenis, J. F., Rocca, H. B., Linssen, G. C. M., Erol-Yilmaz, A., Pronk, A. C. B., Engelen, D. J., van Tooren, R., Koornstra-Wortel, H. J. J., de Boer, R. A., van der Meer, P., et al. (2020) · European Journal of Preventive Cardiology · doi:10.1177/2047487320923185 · Cited by 20

Characterising polypharmacy in the very old: Findings from the Newcastle 85+ Study

Davies, L. E., Kingston, A., Todd, A., & Hanratty, B. (2021) · PLoS ONE · doi:10.1371/journal.pone.0245648 · Cited by 20

Diurnal effects of polypharmacy with high drug burden index on physical activities over 23 h differ with age and sex

Tran, T., Mach, J., Gemikonakli, G., Wu, H. C., Allore, H. G., Howlett, S. E., Little, C. B., & Hilmer, S. N. (2022) · Scientific Reports · doi:10.1038/s41598-022-06039-4 · Cited by 21

Adverse Drug Reactions and Potentially Inappropriate Medication in Older Patients: Analysis of the Portuguese Pharmacovigilance Database

Gomes, D., Herdeiro, M. T., Ribeiro‐Vaz, I., Ferreira, P. L., & Roque, F. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11082229 · Cited by 20

Regulation of drug-metabolizing enzymes by sex-related hormones: clinical implications for transgender medicine

Le, A., Huang, K. J., & Cirrincione, L. R. (2022) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2022.03.006 · Cited by 20

Sex Differences in Efficacy of Pharmacological Therapies in Heart Failure with Reduced Ejection Fraction: A Meta-Analysis

Danielson, C., Lileikyte, G., Ouwerkerk, W., Lam, C. S. P., Erlinge, D., & Teng, T. K. (2022) · ESC Heart Failure · doi:10.1002/ehf2.13974 · Cited by 20

Differences between men and women in response to antiseizure medication use and the likelihood of developing treatment resistant epilepsy

Cepeda, M. S., Teneralli, R. E., Kern, D. M., & Novak, G. (2022) · Epilepsia Open · doi:10.1002/epi4.12632 · Cited by 20

Why do we need sex‐balanced studies of autism?

Nordahl, C. W. (2023) · Autism Research · doi:10.1002/aur.2971 · Cited by 23

Nerve Conduction Differences in a Large Clinical Population: The Role of Age and Sex

Shelly, S., Ramon‐Gonen, R., Paul, P., Klein, C. J., Klang, E., Rahman, N., Nikitin, V., David, M. A. B., & Dori, A. (2023) · Journal of Neuromuscular Diseases · doi:10.3233/jnd-230052 · Cited by 20

Gastric emptying and nutrient absorption of pea protein products differing in heat treatment and texture: A randomized in vivo crossover trial and in vitro digestion study

Roelofs, J. J. M., van Eijnatten, E. J. M., Prathumars, P., de Jong, J., Wehrens, R., Esser, D., Janssen, A. E. M., & Smeets, P. A. M. (2023) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2023.109596 · Cited by 22

Immunosuppression and cancer risk in kidney transplant recipients: A retrospective cohort study

Sapir‐Pichhadze, R., Laprise, C., Beauchamp, M., Kaouache, M., Zhang, X., Vecchia, A. D., Azoulay, L., Franco, E. L., Abrahamowicz, M., & Nicolau, B. F. (2024) · International Journal of Cancer · doi:10.1002/ijc.34875 · Cited by 20

Impact of BMI and Gender on Outcomes in DLBCL Patients Treated with R-CHOP: A Pooled Study from the LYSA

Sarkozy, C., Mounier, N., Delmer, A. J., Hoof, A. V., Karsenti, J. M., Fleck, E., Maerevoet, M., Eisenmann, J. C., Delarue, R., Fabbro, M., et al. (2014) · Lymphoma · doi:10.1155/2014/205215 · Cited by 20

Ancestral Fluoxetine Exposure Sensitizes Zebrafish to Venlafaxine-Induced Reductions in Cortisol and Spawning

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The Possible Role of Sex As an Important Factor in Development and Administration of Lipid Nanomedicine-Based COVID-19 Vaccine

Vulpis, E., Giulimondi, F., Digiacomo, L., Zingoni, A., Safavi‐Sohi, R., Sharifi, S., Caracciolo, G., & Mahmoudi, M. (2021) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.1c00291 · Cited by 21

Pharmacokinetic and metabolomic studies with a BIO 300 Oral Powder formulation in nonhuman primates

Li, Y., Girgis, M. J., Jayatilake, M. M., Serebrenik, A. A., Cheema, A. K., Kaytor, M. D., & Singh, V. K. (2022) · Scientific Reports · doi:10.1038/s41598-022-17807-7 · Cited by 20

Key interindividual determinants in MDMA pharmacodynamics

Papaseit, E., Torrens, M., Pérez‐Mañá, C., Muga, R., & Farré, M. (2018) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2018.1424832 · Cited by 20

Sex bias in immune response: it is time to include the sex variable in studies of autoimmune rheumatic diseases

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A high-fat meal significantly impacts the bioavailability and biphasic absorption of cannabidiol (CBD) from a CBD-rich extract in men and women

Saals, B. A. D. F., de Bie, T. H., Osmanoglou, E., van de Laar, T., Tuin, A. W., van Orten-Luiten, A. C. B., & Witkamp, R. F. (2025) · Scientific Reports · doi:10.1038/s41598-025-87621-4 · Cited by 19

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Malek, A., & Mattison, D. R. (2010) · Expert Review of Obstetrics & Gynecology · doi:10.1586/eog.10.29 · Cited by 19

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Nobili, S., Lavacchi, D., Perrone, G., Vicini, G., Tassi, R., Landini, I., Grosso, A. M., Roviello, G., Mazzanti, R., Santomaggio, C., et al. (2019) · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · doi:10.3727/096504019x15755437099308 · Cited by 19

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Stader, F., & Marzolini, C. (2021) · European Geriatric Medicine · doi:10.1007/s41999-021-00587-0 · Cited by 19

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Arrazuria, R., Kerscher, B., Huber, K. E., Hoover, J. L., Lundberg, C. V., Hansen, J. U., Sordello, S., Renard, S., Aranzana‐Climent, V., Hughes, D., et al. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.988725 · Cited by 19

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Dieterle, M. P., Husari, A., Prozmann, S. N., Wiethoff, H., Stenzinger, A., Röhrich, M., Pfeiffer, U., Kießling, W. R., Engel, H., Sourij, H., et al. (2023) · Biomedicines · doi:10.3390/biomedicines11061732 · Cited by 19

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Cui, L., Chen, Z., Zeng, F., Jiang, X., Han, X., Yuan, X., Wu, S., Feng, H., Lin, D., Lu, W., et al. (2023) · BMC Cancer · doi:10.1186/s12885-023-11564-0 · Cited by 19

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Eyal, S., Rasaby, S., & Ekstein, D. (2013) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2013.09.041 · Cited by 19

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Alhaddad, H., Cisternino, S., Saubaméa, B., Schlatter, J., Chiadmi, F., Risède, P., Smirnova, M., Cochois, V., Tournier, N., Baud, F. J., et al. (2013) · Toxicology · doi:10.1016/j.tox.2013.01.013 · Cited by 19

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Lucca, J., Ramesh, M., & Ram, D. (2017) · Tropical Journal of Medical Research · doi:10.4103/1119-0388.198134 · Cited by 19

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Huang, L., Zeng, Y., Li, Y., Zhu, Y., He, Y., Liu, Y., Robert, A., & Meunier, B. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14122691 · Cited by 18

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Mineiro, R., Santos, C. R. A., Gonçalves, I., Lemos, M. C., Cavaco, J. E. B., & Quintela, T. (2023) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-023-00957-1 · Cited by 18

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Giuliano, L., Durante, V., Battaglia, G., Gasparini, S., Zambrelli, E., Ermio, C., Neve, A. L., Mostacci, B., & the Epilepsy, G. C. O. T. L. (. C. O. T. I. (2024) · CNS Drugs · doi:10.1007/s40263-024-01088-x · Cited by 18

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