Sex Differences in Pharmacokinetics and Pharmacodynamics

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Gender Differences in Pharmacokinetics of Alcohol

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Sex Differences in Pharmacokinetics and Pharmacodynamics

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Effect of age and gender on the activity of human hepatic CYP3A

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Clinical Pharmacological Considerations in Transgender Medicine

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Toxicokinetics of a humanized anti-cocaine monoclonal antibody in male and female rats and lack of cross-reactivity

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Acute brain injury and nanomedicine: sex as a biological variable

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Continuous infusion of beta-lactam antibiotics in pediatric intensive care unit: A monocenter before/after implementation study

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Repurposing Drugs for Senotherapeutic Effect: Potential Senomorphic Effects of Female Synthetic Hormones

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A Focus on Heart Failure Management through Diet and Nutrition: A Comprehensive Review

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Sex Differences in Pharmacokinetics, Pharmacodynamics, and Adverse Drug Reactions of Cardiovascular Drugs

Evelo, A., Leegwater, E., & Visser, L. E. (2024) · Springer eBooks · doi:10.1007/978-3-031-65952-2_32 · Cited by 4

Sex and Gender Differences in Iron Chelation

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Population Pharmacokinetics of Sotorasib in Healthy Subjects and Advanced Solid Tumor Patients Harboring a KRASG12C Mutation from Phase 1 and Phase 2 Studies

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Investigating gender dynamics in forensic toxicology: The role of masculinity and femininity in alcohol and drug abuse

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Implementing a gender-specific perspective in critical care: An expert report from the 2024 iWIN International Meeting

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Pharmacogenetics and Pharmacokinetics of Moxifloxacin in MDR-TB Patients in Indonesia: Analysis for ABCB1 and SLCO1B1

Annisa, N., Afifah, N. N., Santoso, P., Yunivita, V., Brake, L. H. M. T., Aarnoutse, R. E., Barliana, M. I., & Ruslami, R. (2025) · Antibiotics · doi:10.3390/antibiotics14020204 · Cited by 4

Exposome-wide association study of sex-steroid hormones in the U.S. general population: evaluation of complex mixture effects

Lee, J., Jang, H., & Shin, H. (2025) · Environmental Pollution · doi:10.1016/j.envpol.2025.126533 · Cited by 4

Sex differences in coronary artery disease

Seegers, L. M. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-04751-2 · Cited by 4

Sex differences in rates and causes of 30-day readmissions after cardiac electronic device implantations: insights from the Nationwide Readmissions Database

Mohamed, M., Greenspon, A. J., Spall, H. G. C. V., Volgman, A. S., Sharma, P. S., Alraies, M. C., Kwok, C. S., Martin, G. P., Zachariah, D., Patwala, A., et al. (2019) · International Journal of Cardiology · doi:10.1016/j.ijcard.2019.12.012 · Cited by 4

Guideline Adherence of β-blocker Initiating Dose and its Consequence in Hospitalized Patients With Heart Failure With Reduced Ejection Fraction

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Pharmacokinetic variation

Eusuf, D. V., & Thomas, E. (2019) · Anaesthesia & intensive care medicine · doi:10.1016/j.mpaic.2018.12.006 · Cited by 4

Influence of Gender, Body Mass Index, and Age on the Pharmacokinetics of Itraconazole in Healthy Subjects: Non-Compartmental Versus Compartmental Analysis

Miljković, M. N., Rančić, N., Kovačević, A., Cikota‐Aleksić, B., Skadrić, I., Jacevic, V. M., Mikov, M., & Dragojevic-Simic, V. M. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.796336 · Cited by 4

Optimization of Drug Therapy for Heart Failure With Reduced Ejection Fraction Based on Gender

Iacoviello, M., Pugliese, R., Correale, M., & Brunetti, N. D. (2022) · Current Heart Failure Reports · doi:10.1007/s11897-022-00583-w · Cited by 5

The role of sex hormones in targeting stress-induced tobacco craving, stress-reactivity, and smoking with guanfacine among women who smoke

Peltier, M. R., & McKee, S. A. (2023) · Addiction Neuroscience · doi:10.1016/j.addicn.2023.100084 · Cited by 4

Sex differences in patients with heart failure and mildly reduced left ventricular ejection fraction

Liu, Z., Zhu, Y., Chen, S., Wu, M., Huang, H., Peng, K., Zhang, L., Zhao, W., Peng, X., Li, N., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-33733-8 · Cited by 4

Impact of Sex and Genetic Variation in Relevant Pharmacogenes on the Pharmacokinetics and Safety of Valsartan, Olmesartan and Hydrochlorothiazide

Soria‐Chacartegui, P., Zubiaur, P., Ochoa, D., Navares‐Gómez, M., Abbes, H., Villapalos‐García, G., de Miguel, A., González‐Iglesias, E., Rodríguez‐Lopez, A., Mejía-Abril, G. P., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242015265 · Cited by 4

Comparing the efficacy of vedolizumab between males and females: a post-hoc analysis of GEMINI-1 and VARSITY

Chhibba, T., Wong, E. C. L., Reinisch, W., Targownik, L. E., & Narula, N. (2024) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0000000000002759 · Cited by 4

CYP2C19 and CYP2J2 genotypes predict praziquantel plasma exposure among Ethiopian school-aged children

Gebreyesus, T. D., Makonnen, E., Telele, N. F., Barry, A., Mnkugwe, R. H., Gerba, H., Dahl, M., & Aklillu, E. (2024) · Scientific Reports · doi:10.1038/s41598-024-62669-w · Cited by 4

Heart Failure in Women

Jyotsna, M. (2022) · Indian Journal of Cardiovascular Disease in Women · doi:10.25259/mm_ijcdw_482 · Cited by 4

Pooled bioequivalence study database from Turkey: characterization of adverse events and determination of split points based on Gini Index as a promising method

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Leptin receptor gene polymorphisms and sex modify the association between acetaminophen use and asthma among young adults: results from two observational studies

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Understanding and Eliminating Disparities for Women Needing Mechanical Circulatory Support

Bhardwaj, A., & Contreras, J. (2023) · JACC Heart Failure · doi:10.1016/j.jchf.2023.10.014 · Cited by 4

Effects of meal type on the bioavailability of vutiglabridin, a novel anti-obesity agent, in healthy subjects

Won, H., Yoon, D. Y., Lee, S., Cho, J., Oh, J., Jang, I., Yoo, S., & Yu, K. (2024) · Clinical and Translational Science · doi:10.1111/cts.13744 · Cited by 3

Trauma and gender in primary care

Christiansen, D. M. (2023) · Principles of Gender-Specific Medicine · doi:10.1016/b978-0-323-88534-8.00043-2 · Cited by 3

Females present higher dose‐adjusted drug concentrations of metoprolol and allopurinol/oxypurinol than males

Hindi, J., Pilon, M., Meloche, M., Leclair, G., Oussaïd, E., St‐Jean, I., Jutras, M., Gaulin, M., Mongrain, I., Busseuil, D., et al. (2023) · Clinical and Translational Science · doi:10.1111/cts.13497 · Cited by 4

Identification and comparison of sex‐specific serious adverse drug reactions in spontaneous reports and systematically collected reports (ADRED)

Christ, P., Dubrall, D., Just, K. S., Lewke, B. R., Below, M., Stingl, J., Schmid, M. C., & Sachs, B. (2023) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.15941 · Cited by 3

A drug evaluation narrative review of cladribine as a treatment for multiple sclerosis

Martin, S., Arsenault, S. T., & Oh, J. (2025) · Neurodegenerative Disease Management · doi:10.1080/17582024.2025.2520709 · Cited by 3

Older Kidney Transplant Patients Are Over Immunosuppressed Using Standard Protocols With Differential Sex‐Based Complications

Alshaer, I., Hung, R. K. Y., Basu, S., Goldet, G., JONES, G. L., Harber, M. A., Fernando, R., Magee, C. N., Motallebzadeh, R., Caplin, B., et al. (2025) · Journal of Transplantation · doi:10.1155/joot/5547629 · Cited by 3

Effect of Antihypertensive Losartan on Ca2+ Mobilization in the Aorta of Middle-Aged Spontaneously Hypertensive Female Rats

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Sex matters: mechanistic insights into sex-driven patterns of autoimmunity and implications for pharmacotherapy

Guedes, M. S., & Yildiz, D. (2026) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-026-04990-x · Cited by 3

Impact of sex and gender medicine on antibiotic research and use: a narrative review of existing evidence

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Medication adherence in adolescents: physiological, psychosocial, and clinical perspectives

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Sex as a Biological Variable in Tuberculosis Pathogenesis

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Is the Optimal Dose of Heart Failure Medical Therapy Different in Women and Men?

Pabón, M. A., Vaduganathan, M., & Lam, C. S. P. (2024) · European Journal of Heart Failure · doi:10.1002/ejhf.3320 · Cited by 3

An improved experimental model of osteosarcoma lung metastases to investigate innovative therapeutic interventions and sex as a biological variable

Sunbul, F. S., Almuqbil, R. M., Zhang, H., Alhudaithi, S. S., Fernandez, M. E., Aldaqqa, R. R., Garcia, V. A., Robila, V., Halquist, M. S., Gordon, S. W., et al. (2025) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2025.125372 · Cited by 3

Improved recognition memory and reduced inflammation following β-caryophyllene treatment in the Wistar-Kyoto rodent model of treatment-resistant depression

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The Particularities of Arterial Hypertension in Female Sex: From Pathophysiology to Therapeutic Management

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Oral Anticoagulants in Women: What's the Difference? A Narrative Review

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Identifying Predictors of Serious Adverse Events in Antidepressant Treatment from a Decade-Long Nationwide Pharmacovigilance Study: Impact of Dementia and Parkinson’s Disease Treatment

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Co-Treatment of Rauwolfia Vomitoria and Gongronema Latifolium Affects Cerebellar Cell Population in Mice

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Sex Differences in Heart Failure—Female Representation in Heart Failure Studies

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Gender Differences in Drug Therapy

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Evaluation of toxicities related to novel therapy in clinical trials for women with gynecologic cancer

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A sex‐balanced rodent model for evaluating phosphine inhalation toxicity

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Pharmacotherapy: Sex and gender evidence in medication safety and efficacy

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Role of AI in ADME/Tox toward formulation optimization and delivery

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High Spatiotemporal Model-Based Tracking and Environmental Risk-Exposure of Wastewater-Derived Pharmaceuticals across River Networks in Saxony, Germany

Teran-Velasquez, G., Helm, B., & Krebs, P. (2023) · Water · doi:10.3390/w15112001 · Cited by 3

Sex blind: bridging the gap between drug exposure and sex-related gene expression in Danio rerio using next-generation sequencing (NGS) data and a literature review to find the missing links in pharmaceutical and environmental toxicology studies

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Cyclosorus Terminans Extract Alleviates Neuroinflammation in Insulin Resistant Rats

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Hydroxychloroquine: Pharmacokinetics and Toxicity

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Diferencias en función del sexo en las características clínicas y resultados del ensayo clínico CLOROTIC (combinación de diuréticos de asa con tiazidas en la insuficiencia cardiaca descompensada)

Martel, A. C., Trullàs, J. C., Morales‐Rull, J. L., Casado, J., Carrera‐Izquierdo, M., Marteles, M. S., Llàcer, P., Salamanca‐Bautista, P., Manzano, L., & Formiga, F. (2024) · Revista Clínica Española · doi:10.1016/j.rce.2023.11.011 · Cited by 3

Sex as a Critical Variable in Basic and Pre-Clinical Studies of Fibrodysplasia Ossificans Progressiva

Burdick, L. N., DelVichio, A. H., Hanson, L. R., Griffith, B. B., Bouchard, K. R., Hunter, J. W., & Goldhamer, D. J. (2024) · Biomolecules · doi:10.3390/biom14020177 · Cited by 3

Introduction to therapeutic drug monitoring

Dasgupta, A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-18649-3.00005-7 · Cited by 3

Pharmacokinetics of Extended-Release Buprenorphine and Clinical Efficacy for Postoperative Pain Management in the Domestic Ferret (Mustela putorius furo)

Plunkard, J. C. M., Jimenez, I. A., Tarwater, P. M., Craney, M. C., & Villano, J. (2024) · Journal of the American Association for Laboratory Animal Science · doi:10.30802/aalas-jaalas-24-000011 · Cited by 3

Sex-related differences in response to lomitapide in HoFH: A subanalysis of the Pan-European Lomitapide retrospective observational study

Pavanello, C., Suppressa, P., Castiglione, S., Costanzo, A. D., Tramontano, D., Rizzi, L., Steward, K., Calabresi, L., Arca, M., van Lennep, J. E. R., et al. (2024) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2024.119089 · Cited by 3

Adequacy of a hospital-wide standard dose of 7mg/kg bodyweight gentamicin sufficient to achieve an adequate prophylactic maximum serum concentration (Cmax) in burn patients undergoing surgical burn wound treatment

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Gender Differences in Response to Therapy for Cardiovascular Diseases

Corbi, G., Immacolata, A., Komici, K., Michele, C., Lombardi, A., & Ferrara, N. (2017) · Current pharmacogenomics and personalized medicine (Online)/Current pharmacogenomics and personalized medicine · doi:10.2174/1875692115666170508153322 · Cited by 3

INFLUENCE OF SEX DIFFERENCES ON PHARMACOKINETICS OF DRUGS WITHIN THE FRAMEWORK OF BIOEQUIVALENCE STUDIES OF GENERIC MEDICINAL PRODUCTS

Romodanovsky, D. P., Goryachev, D. V., Хохлов, А. Л., & Miroshnikov, A. E. (2018) · Бюллетень Восточно-Сибирского научного центра Сибирского отделения Российской академии медицинских наук · doi:10.29413/abs.2018-3.5.15 · Cited by 3

Sex distribution and sex data handling in published otolaryngology research

Liang, J. J., Belcastro, A., & Levi, J. R. (2019) · The Laryngoscope · doi:10.1002/lary.27871 · Cited by 3

Sex differences in drug-induced QT prolongation

Vicente, J., Zheng, N., Bende, G., & Garnett, C. E. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-817728-0.00072-3 · Cited by 3

Viewing the COVID-19 Pandemic Through a Sex and Gender Lens

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Comparison of rat fetal sex determination using placental gDNA and mRNA via qRT-PCR.

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Global Women’s Eye Health: A Genetic Epidemiologic Perspective

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Gender Differences in Drug Therapy

Fenech, A. G., & Magri, V. P. (2020) · Springer eBooks · doi:10.1007/978-3-319-68864-0_69 · Cited by 3

Therapeutic Drug Monitoring as a Tool for Therapy Optimization

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Pharmacokinetic variation

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Benoxacor is enantioselectively metabolized by microsomes and cytosol from the human liver

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Role of omega-3 and omega-6 endocannabinoids in cardiopulmonary pharmacology

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Comprehensive Vasodilatation in Women with Acute Heart Failure: Novel Insights from the GALACTIC Randomized Controlled Trial

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Gender-Specific Medicine in Pharmaceutical Drug Discovery and Development

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Trimetazidine therapy for diabetic mouse hearts subjected to ex vivo acute heart failure

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Gender-Specific Medicine's Imminent Coming of Age

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Effect of Genotype and Sex of the Host on the Bioavailability of Novel Albendazole Microcrystals Based on Chitosan and Cellulose Derivatives

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Overlooked sex and gender aspects of emerging infectious disease outbreaks: Lessons learned from COVID-19 to move towards health equity in pandemic response

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A rare homozygous form of phosphohexose isomerase.

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Gender, gelijkheid en geneeskunde

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Farmacologia di genere

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