The DOI matches its Crossref record; 178 of the 178 references it cites were found in a registry or an index.
A Review of Therapeutic Effects of Curcumin
Abstract
There is a growing interest in herbal medicine. Scientific studies have demonstrated the beneficial pharmacological effects of curcumin. Curcumin is a bright yellow spice, derived from the rhizome of Curcuma longa Linn. It has been proven that curcumin is a highly pleiotropic molecule which can be a modulator of intracellular signaling pathways that control cell growth, inflammation, and apoptosis. Curcumin might be a potential candidate for the prevention and/or treatment of some diseases due to its anti-oxidant, antiinflammatory activities and an excellent safety profile. We present an updated concise review of currently available animal and clinical studies demonstrating the therapeutic effect of curcumin. Keywords: Curcumin, therapeutic effects, review, herbal medicine, rhizome, intracellular signaling pathways, cell growth, inflammation, apoptosis, anti-oxidant
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3 retracted
Wang, Z., Zhang, Y., Banerjee, S., Li, Y., & Sarkar, F. H. (2006) · Cancer · doi:10.1002/cncr.21904 · Cited by 263
RetractedCurcumin prevents and reverses murine cardiac hypertrophy
Li, H.-L., Liu, C., de Couto, G., Ouzounian, M., Sun, M., Wang, A.-B., Huang, Y., He, C., Shi, Y., Chen, X., et al. (2008) · Journal of Clinical Investigation · doi:10.1172/jci32865 · Cited by 130
RetractedKundu, P., Mohanty, C., & Sahoo, S. K. (2012) · Acta Biomaterialia · doi:10.1016/j.actbio.2012.03.048 · Cited by 51
RetractedBioavailability of curcumin: Problems and promises
Anand, P., Kunnumakkara, A. B., Newman, R. A., & Aggarwal, B. B. (2007) · Molecular Pharmaceutics · doi:10.1021/mp700113r · Cited by 5,543 · cited 1×
“Recent studies discussed on poor bioavailability of curcumin because of poor absorption, rapid metabolism, and rapid systemic elimination [34, 35]; however, comprehensive pharmacokinetic data are still missing.”
BackgroundAnticancer potential of curcumin: preclinical and clinical studies.
Aggarwal, B. B., Kumar, A. J., & Bharti, A. C. (2003) · PubMed · Cited by 2,550
Curcumin as “Curecumin”: From kitchen to clinic
Goel, A., Kunnumakkara, A. B., & Aggarwal, B. B. (2008) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.08.016 · Cited by 2,214
Curcumin: From ancient medicine to current clinical trials
Hatcher, H., Planalp, R., Cho, J., Torti, F. M., & Torti, S. V. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-7452-4 · Cited by 1,843
Aggarwal, B. B., & Harikumar, K. B. (2009) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2008.06.010 · Cited by 1,716
Multiple biological activities of curcumin: A short review
Maheshwari, R. K., Singh, A. K., Gaddipati, J., & Srimal, R. C. (2006) · Life Sciences · doi:10.1016/j.lfs.2005.12.007 · Cited by 1,674
CURCUMIN: THE INDIAN SOLID GOLD
Aggarwal, B. B., Sundaram, C., Malani, N., & Ichikawa, H. (2007) · ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY · doi:10.1007/978-0-387-46401-5_1 · Cited by 1,647
Cited by
The Immunomodulatory and Anti-Inflammatory Role of Polyphenols
Yahfoufi, N., Alsadi, N., Jambi, M., & Matar, C. (2018) · Nutrients · doi:10.3390/nu10111618 · Cited by 1,737
Lee, B., Moon, K. M., & Kim, C. Y. (2018) · Journal of Immunology Research · doi:10.1155/2018/2645465 · Cited by 404
Therapeutic Applications of Curcumin in Diabetes: A Review and Perspective
Quispe, C., Herrera-Bravo, J., Javed, Z., Khan, K., Raza, S., Gulsunoglu-Konuskan, Z., Daştan, S. D., Sytar, O., Martorell, M., Sharifi-Rad, J., et al. (2022) · BioMed Research International · doi:10.1155/2022/1375892 · Cited by 92
Metadata
- Authors
- Noorafshan, A., & Ashkani-Esfahani, S.
- Venue
- Current Pharmaceutical Design
- Publisher
- Bentham Science Publishers Ltd.
- Published
- 2013-04-01
- Volume
- 19
- Issue
- 11
- Pages
- 2032-2046
- ISSN
- 1381-6128 (ISSN-L)
- OpenAlex
- W2015175257
- Cited by
- 317
- References
- 178
- FWCI
- 9.68
- Type
- journal article
- Language
- en
- Open access
- closed
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