The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
The Antioxidant Activity of Coumarins and Flavonoids
Abstract
Coumarins and flavonoids are heterocyclic molecules that have been associated with beneficial effects on human health, such as reducing the risk of cancer, diabetes, cardiovascular and brain diseases. These effects are thought to be related to the radical scavenging effect, due to their antioxidant activities, along with other possible mechanisms, such as anti-inflammatory properties and interaction with several enzymes. Over the past two decades, there have been an increasing number of publications on coumarins and flavonoids, which demonstrate the importance of understanding the chemistry behind the antioxidant activities of both natural and synthesized compounds, considering the benefits from their dietary ingestion as well as pharmacological use. This work aims to review the antioxidant effects of coumarin and flavonoid molecules in humans and the structural aspects that contribute to these effects.
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Cites
Structure-antioxidant activity relationships of flavonoids and phenolic acids
Rice-Evans, C. A., Miller, N. J., & Paganga, G. (1996) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(95)02227-9 · Cited by 9,085
Two to tango: Regulation of Mammalian iron metabolism
Hentze, M. W., Muckenthaler, M. U., Galy, B., & Camaschella, C. (2010) · Cell · doi:10.1016/j.cell.2010.06.028 · Cited by 2,120
Role of oxygen radicals in DNA damage and cancer incidence
Valko, M., Izakovic, M., Mazur, M., Rhodes, C. J., & Telser, J. (2004) · Molecular and Cellular Biochemistry · doi:10.1023/b:mcbi.0000049134.69131.89 · Cited by 1,820
The Haber–Weiss reaction and mechanisms of toxicity
Kehrer, J. P. (2000) · Toxicology · doi:10.1016/s0300-483x(00)00231-6 · Cited by 1,418 · cited 1×
“Furthermore, by combining a Fenton reaction with the reduction of +3 Fe by superoxide (Fe(III) + O2 Fe(II) + O2), the net reaction is known as the Haber-Weiss reaction (O2 + H2O2 O2 + OH + OH ), which results in the formation of the damaging hydroxyl radical from the interaction between superoxide radical and hydrogen…”
BackgroundTransition metals as catalysts of “autoxidation” reactions
Miller, D. (1990) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(90)90148-c · Cited by 739
The wanderings of a free radical
Halliwell, B. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2008.11.008 · Cited by 467
Hollman, P. C. H., Cassidy, A., Comte, B., Heinonen, M., Richelle, M., Richling, E., Serafini, M., Scalbert, A., Sies, H., & Vidry, S. (2011) · The Journal of Nutrition · doi:10.3945/jn.110.131490 · Cited by 406
Moran, J. F., Klucas, R. V., Grayer, R. J., Abian, J., & Becana, M. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(96)00426-1 · Cited by 369
Dugas, A. J., Castañeda-Acosta, J., Bonin, G. C., Price, K. L., Fischer, N. H., & Winston, G. W. (2000) · Journal of Natural Products · doi:10.1021/np990352n · Cited by 319
Kidane, A. G., Salacinski, H., Tiwari, A., Bruckdorfer, K. R., & Seifalian, A. M. (2004) · Biomacromolecules · doi:10.1021/bm0344553 · Cited by 166
Cited by
Antioxidant properties of flavonoids
Banjarnahor, S. D. S., & Artanti, N. (2015) · Medical Journal of Indonesia · doi:10.13181/mji.v23i4.1015 · Cited by 310
Proinflammatory Pathways: The Modulation by Flavonoids
Ribeiro, D., Freitas, M., Lima, J. L. F. C., & Fernandes, E. (2015) · Medicinal Research Reviews · doi:10.1002/med.21347 · Cited by 147
SPF Enhancement Provided by Rutin in a Multifunctional Sunscreen
Tomazelli, L. C., de Assis Ramos, M. M., Sauce, R., Cândido, T. M., Sarruf, F. D., de Oliveira Pinto, C. A. S., de Oliveira, C. A., Rosado, C., Velasco, M. V. R., & Baby, A. R. (2018) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2018.10.015 · Cited by 80
Metadata
- Authors
- Borges Bubols, G., da Rocha Vianna, D., Medina-Remon, A., von Poser, G., Maria Lamuela-Raventos, R., Lucia Eifler-Lima, V., & Cristina Garcia, S.
- Venue
- Mini Reviews in Medicinal Chemistry
- Publisher
- Bentham Science Publishers Ltd.
- Published
- 2013-03-01
- Volume
- 13
- Issue
- 3
- Pages
- 318-334
- ISSN
- 1389-5575 (ISSN-L)
- OpenAlex
- W2114947590
- Cited by
- 357
- References
- 12
- FWCI
- 9.04
- Type
- journal article
- Language
- en
- Open access
- closed
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