The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
Ivermectin, 'Wonder drug' from Japan: the human use perspective
Open accessAbstract
Discovered in the late-1970s, the pioneering drug ivermectin, a dihydro derivative of avermectin--originating solely from a single microorganism isolated at the Kitasato Institute, Tokyo, Japan from Japanese soil--has had an immeasurably beneficial impact in improving the lives and welfare of billions of people throughout the world. Originally introduced as a veterinary drug, it kills a wide range of internal and external parasites in commercial livestock and companion animals. It was quickly discovered to be ideal in combating two of the world's most devastating and disfiguring diseases which have plagued the world's poor throughout the tropics for centuries. It is now being used free-of-charge as the sole tool in campaigns to eliminate both diseases globally. It has also been used to successfully overcome several other human diseases and new uses for it are continually being found. This paper looks in depth at the events surrounding ivermectin's passage from being a huge success in Animal Health into its widespread use in humans, a development which has led many to describe it as a "wonder" drug.
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Cites
Drug resistance in nematodes of veterinary importance: a status report
Kaplan, R. M. (2004) · Trends in Parasitology · doi:10.1016/j.pt.2004.08.001 · Cited by 1,276
Avermectins, New Family of Potent Anthelmintic Agents: Producing Organism and Fermentation
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Ivermectin: A Potent New Antiparasitic Agent
Campbell, W. C., Fisher, M. H., Stapley, E. O., Albers-Schönberg, G., & Jacob, T. A. (1983) · Science · doi:10.1126/science.6308762 · Cited by 825
Drug resistance in veterinary helminths
Wolstenholme, A. J., Fairweather, I., Prichard, R., von Samson-Himmelstjerna, G., & Sangster, N. C. (2004) · Trends in Parasitology · doi:10.1016/j.pt.2004.07.010 · Cited by 813
The genetics of ivermectin resistance in Caenorhabditis elegans
Dent, J. A., Smith, M. M., Vassilatis, D. K., & Avery, L. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.6.2674 · Cited by 455
Adjuvant tamoxifen in the management of operable breast cancer : Scottish Trial
Scottish Cancer Trials Office (1987) · The Lancet · Cited by 428
Ivermectin: 25 years and still going strong
Õmura, S. (2008) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2007.08.023 · Cited by 338
Effect of single-dose ivermectin on Onchocerca volvulus: a systematic review and meta-analysis
Basáñez, M.-G., Pion, S. D., Boakes, E., Filipe, J. A., Churcher, T. S., & Boussinesq, M. (2008) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(08)70099-9 · Cited by 336
Ivermectin, a new broad-spectrum antiparasitic agent
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Ivermectin 20 years on: maturation of a wonder drug
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Cited by
Hit and lead criteria in drug discovery for infectious diseases of the developing world
Katsuno, K., Burrows, J. N., Duncan, K., van Huijsduijnen, R. H., Kaneko, T., Kita, K., Mowbray, C. E., Schmatz, D., Warner, P., & Slingsby, B. T. (2015) · Nature Reviews Drug Discovery · doi:10.1038/nrd4683 · Cited by 607
Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen
Heidary, F., & Gharebaghi, R. (2020) · The Journal of Antibiotics · doi:10.1038/s41429-020-0336-z · Cited by 435
Delost, M. D., Smith, D. T., Anderson, B. J., & Njardarson, J. T. (2018) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.8b00876 · Cited by 409
Kory, P., Meduri, G. U., Varon, J., Iglesias, J., & Marik, P. E. (2021) · American Journal of Therapeutics · doi:10.1097/mjt.0000000000001377 · Cited by 203
Ivermectin versus albendazole or thiabendazole for Strongyloides stercoralis infection
Henriquez-Camacho, C., Gotuzzo, E., Echevarria, J., White Jr, A. C., Terashima, A., Samalvides, F., Pérez-Molina, J. A., & Plana, M. N. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007745.pub3 · Cited by 193
Metadata
- Authors
- CRUMP, A., & OMURA, S.
- Venue
- Proceedings of the Japan Academy, Series B
- Publisher
- Japan Academy
- Published
- 2011
- Volume
- 87
- Issue
- 2
- Pages
- 13-28
- ISSN
- 0386-2208 (ISSN-L)
- 1349-2896
- OpenAlex
- W1991496259
- Cited by
- 368
- References
- 42
- FWCI
- 4.20
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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