Benefits of Mobile Apps for Cancer Pain Management: Systematic Review
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Abstract
Background: Pain ratings reported by patients with cancer continue to increase, and numerous computer and phone apps for managing cancer-related pain have been developed recently; however, whether these apps effectively alleviate patients’ pain remains unknown. Objective: This study aimed to comprehensively evaluate the role of mobile apps in the management of cancer pain. Methods: Literature on the use of apps for cancer pain management and interventions, published before August 2019, was retrieved from the following databases: MEDLINE, Embase, Cochrane, CINAHL, Scopus, and PsycINFO. The effects of apps on cancer pain were evaluated using RevMan5.3 software, and the rates of adverse drug reactions were analyzed using the R Statistical Software Package 3.5.3. Results: A total of 13 studies were selected for the analysis: 5 randomized controlled trials (RCTs), 4 before-after studies, 2 single-arm trials, 1 prospective cohort study, and 1 prospective descriptive study. The 5 RCTs reported data for 487 patients (240 patients in the intervention group and 247 patients in the control group), and the remaining studies reported data for 428 patients. We conducted a meta-analysis of the RCTs. According to the meta-analysis, apps can significantly reduce pain scores (mean difference [MD]=–0.50, 95% CI –0.94 to –0.07, I2=62%, P=.02). We then used apps that have an instant messaging module for subgroup analysis; these apps significantly reduced patients’ pain scores (MD=–0.67, 95% CI –1.06 to –0.28, I2=57%, P<.01). Patients using apps without an instant messaging module did not see a reduction in the pain score (MD=0.30, 95% CI –1.31 to 1.92, I2=70%, P=.71). Overall, patients were highly satisfied with using apps. Other outcomes, such as pain catastrophizing or quality of life, demonstrated greater improvement in patients using apps with instant messaging modules compared with patients not using an app. Conclusions: The use of apps with instant messaging modules is associated with reduced pain scores in patients with cancer-related pain, and patient acceptance of these apps is high. Apps without instant messaging modules are associated with relatively higher pain scores. The presence of an instant messaging module may be a key factor affecting the effect of an app on cancer pain.
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The review added measures such as Flesch-Kincaid metrics and the IMS, which have not been employed in previous app reviews.
“Strengths include the addition of measures, such as the Flesch-Kincaid metrics and the IMS, which have not been employed in previous app reviews [16,21,22].”
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- Authors
- Zheng, C., Chen, X., Weng, L., Guo, L., Xu, H., Lin, M., Xue, Y., Lin, X., Yang, A., Yu, L., Xue, Z., & Yang, J.
- Affiliations
- Fujian Medical University (CN)
- Xiamen Maternal and Child Health Hospital (CN)
- Corresponding author
- Yang, Jing
- ORCID
- Venue
- JMIR mHealth and uHealth
- Publisher
- JMIR Publications Inc.
- Published
- 2020-01-23
- Volume
- 8
- Issue
- 1
- Pages
- e17055
- ISSN
- 2291-5222 (ISSN-L)
- PMC
- PMC7005688
- OpenAlex
- W2995833798
- Cited by
- 69
- References
- 42
- Citations by year
- 2026: 3 · 2025: 15 · 2024: 14 · 2023: 15 · 2022: 10 · 2021: 11 · 2020: 1
- FWCI
- 1.01
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- JMIR mhealth and uhealth (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Keywords
- cancer pain, mobile health apps, pain management, instant messaging, pain scores, patient satisfaction, pain catastrophizing, quality of life, adverse drug reactions, patient acceptance, digital health interventions, patient-provider communication, medication adherence, patient empowerment, patient-centered care
- MeSH terms
- Cancer Pain, Humans, Neoplasms, Quality of Life, Cell Phone, Mobile Applications
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