Tailored web-based interventions for pain: Systematic review and meta-analysis
Open accessAbstract
BACKGROUND: Efforts have multiplied in the past decade to underline the importance of pain management. For both acute and chronic pain management, various barriers generate considerable treatment accessibility issues, thereby providing an opportunity for alternative intervention formats to be implemented. Several systematic reviews on Web-based interventions with a large emphasis on chronic pain and cognitive behavioral therapy have been recently conducted to explore the influence of these interventions on pain management However, to our knowledge, the specific contribution of tailored Web-based interventions for pain management has not been described and their effect on pain has not been evaluated. OBJECTIVE: The primary aim of this systematic review was to answer the following research question: What is the effect of tailored Web-based pain management interventions for adults on pain intensity compared with usual care, face-to-face interventions, and standardized Web-based interventions? A secondary aim was to examine the effects of these interventions on physical and psychological functions. METHODS: We conducted a systematic review of articles published from January 2000 to December 2015. We used the DerSimonian-Laird random effects models with 95% confidence intervals to calculate effect estimates for all analyses. We calculated standardized mean differences from extracted means and standard deviations, as outcome variables were measured on different continuous scales. We evaluated 5 different outcomes: pain intensity (primary outcome), pain-related disability, anxiety, depression, and pain catastrophizing. We assessed effects according to 3 time intervals: short term (<1 month), medium term (1-6 months), and long term (6-12 months). RESULTS: After full-text review, we excluded 31 articles, resulting in 17 eligible studies. Only 1 study concerned acute pain and was removed from the meta-analysis, resulting in 16 studies available for quantitative assessment. Compared with standard care or a waiting list, tailored Web-based intervention showed benefits immediately after, with small effect sizes (<0.40) for pain intensity (10 randomized controlled trials [RCTs], n=1310, P=.003) and pain-related disability (6 RCTs, n=953, P<.001). No other improvements were observed at follow-up in the medium and long terms. Compared with the active control group, no improvements were found for the primary outcome (pain intensity) or any of the outcomes except for a small effect size on pain catastrophizing (2 RCTs, n=333, P<.001) immediately after the intervention. CONCLUSIONS: Tailored Web-based interventions did not prove to be more efficacious than standardized Web-based interventions in terms of pain intensity, pain-related disability, anxiety, and depression. An interesting finding was that some efficacy was shown on pain catastrophizing compared with active control interventions. Considering the diversity of approaches used in tailored Web-based interventions for chronic pain management, their efficacy is yet to be explored. Moreover, their contribution to acute pain management is embryonic. TRIAL REGISTRATION: International prospective register of systematic reviews (PROSPERO): CRD42015027669; http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42015027669 (Archived by WebCite at http://www. webcitation.org/6uneWAuyR).
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Written from the paper’s full text.
TL;DR
This systematic review and meta-analysis found that tailored Web-based pain interventions produced small short-term improvements in pain intensity and pain-related disability versus standard care or waitlist, but not versus active controls except for pain catastrophizing. Evidence was limited by few active-control studies, heterogeneous intervention approaches, and only one acute pain trial.
Key findings
- Versus standard care or waitlist, tailored Web-based interventions showed small short-term benefits for pain intensity (10 RCTs, n=1310, SMD –0.21, 95% CI –0.34 to –0.07, P=.003; I²=29%) and pain-related disability (6 RCTs, n=953, SMD –0.38, 95% CI –0.59 to –0.16, P<.001; I²=58%); no significant medium- or long-term improvements were observed.
- Versus active control, no significant improvements were found for pain intensity short term (4 RCTs, n=543, SMD –0.09, P=.32) or medium term (4 RCTs, n=630, SMD –0.14, P=.09), nor for pain-related disability, anxiety, or depression; the only significant effect was short-term pain catastrophizing (2 RCTs, n=333, SMD –0.46, 95% CI –0.67 to –0.24, P<.001; I²=0%).
- The review included 17 studies; 16 chronic pain studies entered meta-analysis, and the single acute pain study after cardiac surgery was removed. Mean completion rate was 77.6%, attrition ranged from 5% to 56% (average 22%), mean age was 48.2 years, and 71% of participants were female.
- Feedback was used in every intervention, content matching in half of studies, and personalization was difficult to assess because of limited intervention descriptions.
Methods
- Systematic review and meta-analysis of RCTs in adults with any pain, published January 2000 to December 2015, searched in MEDLINE, Embase, CINAHL, PsycINFO, Web of Science, and the Cochrane Library; protocol registered as PROSPERO CRD42015027669.
- Eligible studies involved tailored Web-based pain management with at least one tailoring strategy (personalization, feedback, or adaptation/content matching), compared with passive control (usual care or waitlist) or active control (face-to-face or standardized Web-based intervention); pain intensity was a mandatory outcome.
- DerSimonian-Laird random effects models calculated standardized mean differences with 95% CIs for pain intensity, pain-related disability, anxiety, depression, and pain catastrophizing at short term (<1 month), medium term (1-6 months), and long term (6-12 months); heterogeneity was assessed with I².
Limitations
- Stated in the paper: only 5 studies were included in the active-control meta-analysis, so those results should be interpreted with caution; intervention approaches and dosage varied widely, preventing clear conclusions about efficacy; only half used content matching; attrition and fidelity were challenges; only one acute pain study was found; most participants were women and sex differences were not considered; focusing on the Roland Morris Disability Questionnaire and Brief Pain Inventory may have influenced disability results.
- Evident from the text: most studies had high risk of bias for blinding of participants/personnel and outcome assessment, and many had unclear risk for random sequence generation or allocation concealment; small numbers of studies per analysis limited funnel plot assessment and subgroup analyses.
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- Findingown data
Compared with active control, tailored Web-based interventions showed no improvement in pain intensity immediately after the intervention.
“Compared with the active control group, no improvements were found for the primary outcome (pain intensity) or any of the outcomes except for a small effect size on pain catastrophizing (2 RCTs, n=333, P<.001) immediately after the intervention.”
Quote in the paperSubstantial claim - Findingown data
No significant short-term reductions in depression were found with tailored Web-based interventions compared with standard care or waitlist control (7 RCTs, n=635, SMD -0.33, 95% CI -0.66 to 0.00, P=.05).
“or depression (7 RCTs, n=635, SMD –0.33, 95% CI –0.66 to 0.00, P=.05; I2=73%)”
Quote in the paperSubstantial claim - Findingown data
The beneficial short-term effect of tailored Web-based interventions on pain intensity was not sustained at long term (5 RCTs, n=1909, SMD -0.09, 95% CI -0.18 to 0.00, P=.05).
“and long term (5 RCTs, n=1909, SMD –0.09, 95% CI –0.18 to 0.00, P=.05; I2=0%)”
Quote in the paperSubstantial claim - Findingown data
The beneficial short-term effect of tailored Web-based interventions on pain intensity was not sustained at medium term (4 RCTs, n=987, SMD -0.08, 95% CI -0.30 to 0.13, P=.45).
“The beneficial pain relief effect was not sustained at medium term (4 RCTs, n=987, SMD –0.08, 95% CI –0.30 to 0.13, P=.45; I2=48%)”
Quote in the paperSubstantial claim - Findingown data
Compared with active control, tailored Web-based interventions produced a small effect on pain catastrophizing immediately after the intervention (2 RCTs, n=333, P<.001).
“except for a small effect size on pain catastrophizing (2 RCTs, n=333, P<.001) immediately after the intervention.”
Quote in the paperSubstantial claim
- Findingown data
No significant short-term reductions in anxiety were found with tailored Web-based interventions compared with standard care or waitlist control (5 RCTs, n=507, SMD -0.08, 95% CI -0.50 to 0.34, P=.70).
“We found no significant short-term reductions in anxiety (5 RCTs, n=507, SMD –0.08, 95% CI –0.50 to 0.34, P=.70; I2=79%)”
Quote in the paperNot a substantial claim - Findingown data
In adults with chronic pain, tailored Web-based interventions compared with standard care or waitlist control produced a small beneficial short-term effect on pain-related disability (6 RCTs, n=953, SMD -0.38, 95% CI -0.59 to -0.16, P<.001).
“We entered 6 studies (n=953) into the meta-analysis of the short-term effect of Web-based tailored interventions on pain-related disability. The overall effect was significantly beneficial with a small effect size, although heterogeneity was high (SMD –0.38, 95% CI –0.59 to –0.16, P<.001; I2=58%).”
Quote in the paperSubstantial claim - Findingown data
The effect of tailored Web-based interventions on pain-related disability at medium term was not significant (3 RCTs, n=411, SMD -0.07, 95% CI -0.26 to 0.13, P=.49).
“We entered 3 studies (n=411) into the meta-analysis of the medium-term effect on pain-related disability. The overall effect, although in favor of the experimental group, was not significant (SMD –0.07, 95% CI –0.26 to 0.13, P=.49; I2=0%).”
Quote in the paperSubstantial claim - Findingown data
Compared with active control, tailored Web-based interventions showed no improvement in any outcome except pain catastrophizing immediately after the intervention.
“Compared with the active control group, no improvements were found for the primary outcome (pain intensity) or any of the outcomes except for a small effect size on pain catastrophizing (2 RCTs, n=333, P<.001) immediately after the intervention.”
Quote in the paperSubstantial claim - Findingown data
The medium-term effect on anxiety was not significant (2 studies, n=411, SMD 0.03, 95% CI -0.27 to 0.32, P=.87; I2=55%).
“In regard to medium-term effect on anxiety, we entered 2 studies (n=411) into the meta-analysis, and the overall effect was not significant (SMD 0.03, 95% CI –0.27 to 0.32, P=.87; I2=55%).”
Quote in the paperNot a substantial claim - Findingown data
The tailored Web-based intervention did not relieve pain-related disability significantly better than active control in the medium term (2 RCTs, n=411, SMD -0.01, 95% CI -0.20 to 0.19, P=.93; I2=0%).
“or medium term (2 RCTs, n=411, SMD –0.01, 95% CI –0.20 to 0.19, P=.93; I2=0%)”
Quote in the paperSubstantial claim - Findingown data
The medium-term effect on depression was not significant (2 studies, n=411, SMD -0.04, 95% CI -0.30 to 0.21, P=.74; I2=43%).
“We explored the medium-term effect on depression with 2 studies (n=411). The overall effect was not significant (SMD –0.04, 95% CI –0.30 to 0.21, P=.74; I2=43%).”
Quote in the paperNot a substantial claim - Findingreasoning
The 2 studies included in the pain catastrophizing analysis were quite different.
“The 2 studies included in this analysis were quite different [46,52].”
Quote in the paperSubstantial claim0 of 2 sources checked - Findingown data
The tailored Web-based intervention did not relieve pain significantly better than active control in the medium term (4 RCTs, n=630, SMD -0.14, 95% CI -0.29 to 0.02, P=.09; I2=0%).
“or medium term (4 RCTs, n=630, SMD –0.14, 95% CI –0.29 to 0.02, P=.09; I2=0%)”
Quote in the paperSubstantial claim - Findingown data
Compared with standard care or waiting list, pain-related disability was improved immediately after the tailored Web-based intervention with a small effect size (<0.40).
“Compared with standard care or waiting list, pain intensity (10 RCTs, n=1310) and pain-related disability (6 RCTs, n=953) were improved immediately after the tailored Web-based intervention with small effect sizes (ie, <0.40).”
Quote in the paperSubstantial claim - Findingown data
Meta-analyses conducted in our study with the active control group included very few studies.
“It is also noteworthy that meta-analyses conducted in our study with the active control group included very few studies.”
Quote in the paperNot a substantial claim - Findingown data
The only 2 studies in our review that reported moderate effects on pain had all participants with a moderate level of pain intensity at baseline.
“This was true for the only 2 studies in our review that reported moderate effects on pain [53,54]. All participants had a moderate level of pain intensity at baseline.”
Quote in the paperSubstantial claim0 of 2 sources checked - Findingown data
The only significant effect of the tailored Web-based intervention was observed for pain catastrophizing in the short term (2 RCTs, n=333, SMD -0.46, 95% CI -0.67 to -0.24, P<.001; I2=0%).
“The only significant effect of the tailored Web-based intervention was observed for pain catastrophizing in the short term (2 RCTs, n=333, SMD –0.46, 95% CI –0.67 to –0.24, P<.001; I2=0%).”
Quote in the paperSubstantial claim - Findingown data
In the narrative review, the experimental group reported less pain interference with breathing and coughing (P=.04).
“However, less pain interference with breathing and coughing (P=.04) was reported by the experimental group, as well as fewer negative pain beliefs and attitudes (P=.02).”
Quote in the paperNot a substantial claim - Findingown data
In the narrative review, the Web-based tailored intervention compared with standard care showed no effect on pain intensity.
“The Web-based tailored intervention was compared with standard care. No effect on pain intensity was recorded.”
Quote in the paperNot a substantial claim - Findingown data
Most studies compared the tailored Web-based intervention versus standard or waiting-list control (n=12).
“Most of the studies compared the tailored Web-based intervention versus standard or waiting-list control (n=12).”
Quote in the paperNot a substantial claim - Findingown data
The tailored Web-based intervention did not relieve pain significantly better than active control in the short term (4 RCTs, n=543, SMD -0.09, 95% CI -0.25 to 0.08, P=.32; I2=0%).
“The tailored Web-based intervention did not relieve pain significantly better than active control in the short term (4 RCTs, n=543, SMD –0.09, 95% CI –0.25 to 0.08, P=.32; I2=0%)”
Quote in the paperSubstantial claim - Findingown data
A total of 17 studies met the inclusion criteria.
“A total of 17 studies met the inclusion criteria.”
Quote in the paperSubstantial claim - Findingown data
The short-term effect on anxiety was not significant (3 studies, n=450, SMD -0.05, 95% CI -0.24 to 0.13, P=.56; I2=0%).
“We entered 3 studies (n=450) into the meta-analysis of the short-term effect on anxiety. The overall effect was not significant (SMD –0.05, 95% CI –0.24 to 0.13, P=.56; I2=0%).”
Quote in the paperNot a substantial claim - Findingown data
Half of the included studies (n=8) used a hybrid format including telephone or face-to-face contact with a therapist.
“All studies used feedback as 1 of the tailoring mechanisms, and half of them (n=8) used a hybrid format including telephone or face-to-face contact with a therapist.”
Quote in the paperNot a substantial claim - Findingown data
The short-term effect on depression was not significant (3 studies, n=450, SMD -0.09, 95% CI -0.28 to 0.09, P=.33; I2=0%).
“We entered 3 studies (n=450) into the meta-analysis to analyze the short-term effect on depression. The overall effect was not significant (SMD –0.09, 95% CI –0.28 to 0.09, P=.33; I2=0%).”
Quote in the paperNot a substantial claim - Findingown data
Compared with standard care or waiting list, pain intensity was improved immediately after the tailored Web-based intervention with a small effect size (<0.40).
“Compared with standard care or waiting list, pain intensity (10 RCTs, n=1310) and pain-related disability (6 RCTs, n=953) were improved immediately after the tailored Web-based intervention with small effect sizes (ie, <0.40).”
Quote in the paperSubstantial claim - Findingown data
No other improvements were observed at follow-up in the medium and long terms.
“No other improvements were observed at follow-up in the medium and long terms.”
Quote in the paperSubstantial claim - Findingown data
All included studies used feedback as one of the tailoring mechanisms.
“All studies used feedback as 1 of the tailoring mechanisms, and half of them (n=8) used a hybrid format including telephone or face-to-face contact with a therapist.”
Quote in the paperNot a substantial claim - Findingown data
In the narrative review, the experimental group reported fewer negative pain beliefs and attitudes (P=.02).
“However, less pain interference with breathing and coughing (P=.04) was reported by the experimental group, as well as fewer negative pain beliefs and attitudes (P=.02).”
Quote in the paperNot a substantial claim - Findingnone given
We could include only 5 studies in the meta-analysis focusing on active control groups.
“Although our study is 1 of the few making a distinction between comparators, we could include only 5 studies in the meta-analysis focusing on active control groups.”
Quote in the paperSubstantial claim - Findingcitation
Only half of the interventions used the mechanism of content matching.
“Another observation regarding intervention content is that only half of the interventions used the mechanism of content matching, which is thought to be the essence of tailored approaches [21].”
Quote in the paperNot a substantial claim - Findingown data
None of the included interventions have taken into account sex differences in terms of pain experience and coping styles.
“These interventions are tailored to some extent, but none of them have taken into account sex differences in terms of pain experience and coping styles.”
Quote in the paperSubstantial claim - Findingcitation
The only 2 studies that reported moderate effects on pain intensity did not use content matching but rather a hybrid format involving telephone contact with a therapist.
“While the only 2 studies that reported moderate effects (ie, <0.50) on pain intensity did not use content matching but rather a hybrid format involving telephone contact with a therapist [53,54]”
Quote in the paperSubstantial claim0 of 2 sources checked - Findingown data
A major difference in our results is related to the heterogeneity of intervention approaches found in tailored Web-based interventions for pain management as opposed to traditional CBT.
“Although our results are consistent with other meta-analyses, a major difference in our results is related to the heterogeneity of intervention approaches that we found in tailored Web-based interventions for pain management as opposed to traditional CBT.”
Quote in the paperSubstantial claim - Findingown data
The attrition rate ranged from 5% to 56% with an average of 22%.
“The attrition rate ranged from 5% to 56% with an average of 22%, even though all interventions included some kind of feedback, with half of them using human interaction.”
Quote in the paperNot a substantial claim - Findingown data
We found only 1 intervention for acute pain.
“Lastly, we found only 1 intervention for acute pain, which highlights the need to explore the avenue of tailored Web-based interventions for this type of pain and for the prevention of chronic pain.”
Quote in the paperSubstantial claim - Findingcitation
The majority of participants in the included studies were women.
“The majority of participants in the included studies were women, which was observed in other meta-analyses on Web-based interventions for pain management [18,19].”
Quote in the paperNot a substantial claim0 of 2 sources checked - Findingown data
Some efficacy was shown in pain catastrophizing compared with active control interventions.
“An interesting finding was that some efficacy was shown in pain catastrophizing compared with active control interventions.”
Quote in the paperSubstantial claim - Findingown data
The dosage of interventions was very diverse.
“The dosage of interventions was also very diverse, ranging from 2 sessions per week for 3 weeks [51] or 5 sessions per week for 4 weeks [46,47] to 12 to 15 weekly sessions [39] or even weekly reminders for 12 months [55].”
Quote in the paperSubstantial claim0 of 4 sources checked - Interpretationown data
Some efficacy was shown on pain catastrophizing compared with active control interventions.
“An interesting finding was that some efficacy was shown on pain catastrophizing compared with active control interventions.”
Quote in the paperSubstantial claim - Premisecitation
Conveying health information without considering individual differences may inhibit behavior change.
“Experts in health behavior change have shown that conveying health information without considering individual differences may inhibit behavior change [20-26].”
Quote in the paperSubstantial claim0 of 7 sources checked- cites [20] source
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- cites [21] source
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- cites [22] source
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- cites [23] source
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- cites [24] Petty, R, 2004, Perspectives on Persuasion, Social Influence, and Compliance Gaining
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- cites [25] source
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- cites [26] Petty, R, 1986, Communication and Persuasion: Central and Peripheral Routes to Attitude Change source
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- Study design and conductown data
Attrition risk of bias was high in 7 studies regarding incomplete data.
“We found attrition risk of bias in 7 studies that presented a high risk regarding incomplete data [48,51,56-58,60,61].”
Quote in the paperNot a substantial claim0 of 7 sources checked- cites [48] Andersson, G, 2003, Headache source
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- cites [51] source
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- cites [56] source
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- cites [60] source
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- cites [61] Ström, L, 2000, J Consult Clin Psychol source
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- Interpretationown data
Tailored Web-based interventions did not prove to be more efficacious than standardized Web-based interventions in terms of pain intensity, pain-related disability, anxiety, and depression.
“Tailored Web-based interventions did not prove to be more efficacious than standardized Web-based interventions in terms of pain intensity, pain-related disability, anxiety, and depression.”
- Also stated in: § Implications and Conclusion · plain
“Tailored Web-based interventions did not prove to be more efficacious than standardized Web-based interventions in terms of pain intensity, pain-related disability, anxiety, and depression.”
Quote in the paperSubstantial claim- Rests on an assumption: The active control groups in the included studies are equivalent to standardized Web-based interventions.
- Also stated in: § Implications and Conclusion · plain
- Study design and conductown data
Long-term effects on pain could not be analyzed because of lack of assessments available at this time point.
“We could not analyze the long-term effects on pain because of lack of assessments available at this time point.”
Quote in the paperNot a substantial claim - Premisecitation
Tailored Web-based interventions have been recognized for statistically significant effect sizes for health behavior change among diverse populations facing chronic disease.
“Clinically relevant results, such as adopting a healthy lifestyle or adhering to medication, and statistically significant effect sizes of tailored Web-based interventions have been recognized for health behavior change among diverse populations facing chronic disease [20,29,30].”
Quote in the paperSubstantial claim0 of 3 sources checked - Premisecitation
Other systematic reviews and meta-analyses on Web-based CBT, as well as traditional CBT, also reported small effects in the reduction of pain posttreatment compared with standard care or waiting list.
“Other systematic reviews and meta-analyses on Web-based CBT [15,18,19], as well as traditional CBT [65], also reported small effects in the reduction of pain posttreatment compared with standard care or waiting list.”
Quote in the paperNot a substantial claim0 of 4 sources checked - Interpretationcitation
Our results in relation to the active control comparator are in concordance with a previous meta-analysis on traditional psychological therapies for chronic pain, which concluded that there was no evidence of efficacy of CBT and behavioral therapy on pain.
“Our results in relation to the active control comparator are in concordance with a previous meta-analysis on traditional psychological therapies for chronic pain, which concluded that there was no evidence of efficacy of CBT and behavioral therapy on pain [65].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [65] source
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- Interpretationown data
Regardless of the type of comparison used (usual treatment or active control), effects were redundantly small.
“Regardless of the type of comparison used (ie, usual treatment or active control), effects were redundantly small, which poses a question concerning the adequacy of pain reduction as an outcome.”
Quote in the paperSubstantial claim - Study design and conductown data
Long-term effect on anxiety could not be explored due to a lack of assessments available at this time point.
“Long-term effect on anxiety could not be explored due to a lack of assessments available at this time point.”
Quote in the paperNot a substantial claim - Study design and conductown data
Medium-term and long-term effects on pain catastrophizing could not be explored due to lack of assessments available at this time point in this subgroup of studies.
“Medium-term and long-term effects could not be explored due to lack of assessments available at this time point in this subgroup of studies.”
Quote in the paperNot a substantial claim - Premiseown data
That meta-analysis did not distinguish between medium-term and long-term intervals.
“However, evaluation of effects at follow-up did not distinguish between medium-term and long-term intervals (eg, 3 and 12 months).”
Quote in the paperNot a substantial claim - Premisecitation
One meta-analysis showed that small positive effects on pain-related disability were maintained at follow-up (3 months or more).
“One meta-analysis showed that small positive effects on pain-related disability were maintained at follow-up (3 months or more) [18].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [18] source
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- Study design and conductown data
Long-term effects on depression could not be analyzed due to a lack of assessments at this time point.
“Long-term effects on depression could not be analyzed due again to a lack of assessments at this time point.”
Quote in the paperNot a substantial claim - Study design and conductown data
The long-term effect on pain-related disability could not be analyzed due to a lack of assessments available at this time point.
“The long-term effect on pain-related disability could not be analyzed due to a lack of assessments available at this time point.”
Quote in the paperNot a substantial claim - Premisenone given
That meta-analysis did not discriminate between active controls and standard or waitlist controls.
“Moreover, the meta-analysis did not discriminate between active controls and standard or waitlist controls.”
Quote in the paperNot a substantial claim - Interpretationreasoning
This variation in intervention approaches does not allow for gauging the influence of these interventions.
“This variation does not allow for gauging the influence of these interventions.”
Quote in the paperSubstantial claim - Premisecitation
It has been shown that Web-based tailored interventions that are preventive in nature and targeting a general population, not a specific condition, were more successful.
“Hence, it has been shown that Web-based tailored interventions that are preventive in nature and targeting a general population, not a specific condition, were more successful [30].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [30] source
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- Premisecitation
It has been observed that pain management interventions with a duration of less than 8 weeks are more effective.
“In fact, it has been observed that pain management interventions with a duration of less than 8 weeks are more effective [69].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [69] source
Not checked in the free run.
- May combine two claims. 20
- The quote only partly states this claim. 2
- Classified as probably not a substantial claim. 16
May combine two claims.
Findingown dataOnly 1 of the 17 eligible studies concerned acute pain; it was removed from the meta-analysis, leaving 16 studies for quantitative assessment.
“Only 1 study concerned acute pain and was removed from the meta-analysis, resulting in 16 studies available for quantitative assessment.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataThe systematic review excluded 31 articles after full-text review and included 17 eligible studies.
“After full-text review, we excluded 31 articles, resulting in 17 eligible studies.”
Quote in the paperNot a substantial claimThe quote only partly states this claim.
Findingown dataIn adults with chronic pain, tailored Web-based interventions compared with standard care or waitlist control produced a small beneficial short-term effect on pain intensity (10 RCTs, n=1310, SMD -0.21, 95% CI -0.34 to -0.00, P=.003).
“We entered 10 studies (n=1310) into an analysis of the short-term effect of Web-based tailored interventions on pain intensity. The overall effect of Web-based tailored interventions on pain intensity was beneficial, with a small effect size and no significant heterogeneity (SMD –0.21, 95% CI –0.34 to –0.0, P=.003; I2=29%).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataWhen comparing the active control group, no improvements were found for the primary outcome (pain intensity) or any of the outcomes except for a small effect size on pain catastrophizing immediately after the intervention.
“When comparing the active control group, we found no improvements for the primary outcome (pain intensity) or any of the outcomes except for a small effect size on pain catastrophizing (2 RCTs, n=333) immediately after the intervention.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataThe 2 studies both used content matching but used different format and different approach.
“Although they both used content matching, they used different format (hybrid vs not), and a different approach (CBT and motivational vs CBT, acceptance and commitment therapy, and mindfulness).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingown dataFunnel plot asymmetry was observed at the bottom, possibly reflecting moderate heterogeneity due to the inclusion of small studies.
“We observed some asymmetry at the bottom, possibly reflecting moderate heterogeneity due to the inclusion of small studies.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataOnly 1 study concerned acute pain, which was removed from the meta-analysis, resulting in 16 studies available for quantitative assessment.
“Only 1 study concerned acute pain, which we removed from the meta-analysis, resulting in 16 studies available for quantitative assessment.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenThe levels of catastrophizing recorded were high.
“Nonetheless, it is important to underline that the levels of catastrophizing recorded were high.”
Quote in the paperNot a substantial claimThe quote only partly states this claim.
Findingown dataThe tailored Web-based intervention did not relieve pain-related disability significantly better than active control in the short term (2 RCTs, n=426, SMD -0.09, 95% CI -0.28 to 0.10, P=.37; I2=0%).
“The tailored Web-based intervention did not relieve pain significantly better than the active control in the short term (2 RCTs, n=426, SMD –0.09, 95% CI –0.28 to 0.10, P=.37; I2=0%)”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataSelected studies included interventions profoundly influenced by CBT, but approaches were oftentimes multimodal and varied.
“Selected studies included interventions profoundly influenced by CBT, but approaches were oftentimes multimodal and varied from wearing a pedometer and physical activity coaching to relaxation and mindfulness.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFeedback was used in all studies but content matching was used in only half of the studies.
“Feedback was used in all studies but content matching, the most important tailoring ingredient, was used in only half of the studies.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenMany of the interventions included an educational aspect related to management of a specific chronic disease and wellness.
“Many of the interventions also included an educational aspect related to management of a specific chronic disease and wellness.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductcitationThe detailed protocol was published and registered with PROSPERO (CRD42015027669).
“The detailed protocol was published [34] and registered with the international prospective register of systematic reviews (no CRD42015027669).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [34] source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataData were extracted independently by 2 teams of 2 reviewers using DistillerSR, and disagreements were resolved by discussion until 100% agreement.
“Data were extracted independently by 2 teams of 2 reviewers (GM and MaB; CG and MeB) composed of 1 doctoral student and 1 researcher using the software DistillerSR v2 (Evidence Partners Inc).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataRisk of bias for the 17 selected studies was assessed by 2 teams of reviewers using the Cochrane Collaboration tool, and discrepancies were discussed between the teams.
“Risk of bias for the 17 selected studies was assessed by the 2 teams of reviewers using the Cochrane Collaboration tool [41-43], and any discrepancies between reviewers were discussed between the 2 teams.”
Quote in the paperNot a substantial claim0 of 3 sources checkedMay combine two claims.
Study design and conductown dataSelective reporting was judged low risk except in 4 studies, where it was unclear.
“We judged selective reporting as low risk except in 4 studies (unclear) [39,59].”
Quote in the paperNot a substantial claim0 of 2 sources checkedProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataFunnel plots were constructed for only 1 analysis because fewer than 10 studies were included in each analysis.
“We constructed funnel plots for only 1 analysis due to the small number of studies included in each analysis (n<10) [63,64].”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [63] Sterne, J, 2008, Cochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series
Not checked in the free run.
- cites [64] Sterne, JAC, 2011, BMJ source
Not checked in the free run.
Probably not a substantial claim: may not pass S4 (based).
Interpretationnone givenThe contribution of tailored Web-based interventions to acute pain management is embryonic.
“Moreover, their contribution to acute pain management is embryonic.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationThe systematic review protocol was developed based on PRISMA guidelines for reporting systematic reviews evaluating health care interventions.
“This systematic review protocol has been developed based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for reporting systematic reviews evaluating health care interventions [31-33].”
Quote in the paperNot a substantial claim0 of 3 sources checkedClassified as probably not a substantial claim.
InterpretationreasoningThe efficacy of tailored Web-based interventions for chronic pain management is yet to be explored.
“Considering the diversity of approaches used in tailored Web-based interventions for chronic pain management, their efficacy is yet to be explored.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataEligibility was assessed independently in an unblinded standardized manner by 2 team members, and results were compared.
“Eligibility was assessed independently in an unblinded standardized manner by 2 team members (GM, CG) and results were then compared.”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductown dataAll included studies except 2 presented a high risk of performance bias regarding blinding of participants, and the same was the case for detection bias.
“In terms of performance bias, all studies except for 2 (low and unclear risks) [48,52] presented a high risk in regard to blinding of participants, which was also the case for detection bias.”
Quote in the paperNot a substantial claim0 of 2 sources checkedMay combine two claims.
PremisecitationOne meta-analysis on Web-based CBT found a small effect on pain catastrophizing posttreatment, but reported high heterogeneity and used standard care or waiting list as comparator.
“One meta-analysis on Web-based CBT found a small effect on pain catastrophizing posttreatment [19]. However, a high heterogeneity was reported and the comparator was standard care or waiting list.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [19] source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
InterpretationreasoningVariations in samples coming from the general population as opposed to outpatients from a clinic could be a potential explanation for the funnel plot asymmetry.
“Variations in samples coming from the general population as opposed to outpatients from a clinic could also be a potential explanation.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
PremisecitationPrevious systematic reviews on Web-based interventions for pain concluded that results were promising in terms of pain reduction and improvement of functional and emotional well-being.
“Overall, their authors concluded that results were promising in terms of pain reduction, and improvement of functional and emotional well-being.”
Quote in the paperSubstantial claim0 of 6 sources checkedMay combine two claims.
PremisecitationAnother meta-analysis found a small effect on depression posttreatment compared with standard care, but that analysis merged both depression and anxiety outcomes.
“Another meta-analysis found a small effect on depression posttreatment compared with standard care. However, that analysis merged both depression and anxiety outcomes [19].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [19] source
Not checked in the free run.
May combine two claims.
PremisecitationThis attrition rate is similar to the rate found in another meta-analysis, underlining that there was no difference in attrition even when participants received more guidance as opposed to no reminders or feedback.
“This rate is similar to the rate found in another meta-analysis, underlining that there was no difference in attrition even when participants received more guidance as opposed to no reminders or feedback [19].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [19] source
Not checked in the free run.
May combine two claims.
Interpretationnone givenThis is, to our knowledge, the first review examining tailored Web-based interventions and using active control groups as a comparator.
“Although several meta-analyses and systematic reviews of Web-based interventions for pain management have been conducted, this is, to our knowledge, the first examining tailored Web-based interventions and using active control groups as a comparator.”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationreasoningSimilar findings to other meta-analyses on Web-based interventions for pain management were generated, meaning that these interventions may have a short-term effect on pain intensity and disability compared with usual care.
“Similar findings to other meta-analyses on Web-based interventions for pain management were generated, meaning that these interventions may have a short-term effect on pain intensity and disability compared with usual care.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationA recent study (n=1371) in the context of a rehabilitation program found that women have better activity level, pain acceptance, and social support, while men report more fear of movement and mood disturbances.
“A recent study (n=1371) in the context of a rehabilitation program found that women have better activity level, pain acceptance, and social support, while men report more fear of movement and mood disturbances [70].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [70] source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationContent matching is thought to be the essence of tailored approaches.
“which is thought to be the essence of tailored approaches [21]”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [21] source
Not checked in the free run.
Classified as probably not a substantial claim.
Study design and conductreasoningFocusing on the Roland Morris Disability Questionnaire and the Brief Pain Inventory as the 2 most commonly used measures for pain-related disability could have influenced our results.
“In an effort to decrease heterogeneity in measures and their involved concepts when looking at pain-related disability, we focused on the 2 most commonly used measures: the Roland Morris Disability Questionnaire and the Brief Pain Inventory. This could have influenced our results.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationA meta-analysis on tailored Web-based interventions in general found that expert input does not necessarily mean more efficacy.
“A meta-analysis on tailored Web-based interventions in general found that expert input does not necessarily mean more efficacy [30].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [30] source
Not checked in the free run.
The paper relies on this without support.
The specific contribution of tailored Web-based interventions for pain management has not been described and their effect on pain has not been evaluated.
“However, to our knowledge, the specific contribution of tailored Web-based interventions for pain management has not been described and their effect on pain has not been evaluated.”
The paper relies on this without support.
The active control groups in the included studies are equivalent to standardized Web-based interventions.
“Tailored Web-based interventions did not prove to be more efficacious than standardized Web-based interventions in terms of pain intensity, pain-related disability, anxiety, and depression.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Internet-based CBT interventions for chronic somatic (pain) conditions are more effective than passive control conditions for outcomes such as pain intensity, fatigue, pain-related interference/disability, pain acceptance, health-related quality of life, distress, depression, anxiety, and catastrophizing.
“Specifically, internet-based (CBT) interventions for chronic somatic (pain) conditions are found to be more effective than passive control conditions for outcomes such as pain intensity, fatigue, pain-related interference/disability, pain acceptance, health-related quality of life, distress, depression, anxiety, and catastrophizing (van Beugen et al., 2014; Buhrman et al., 2016; Martorella et al.,”
From Guided internet-based cognitive-behavioral therapy for patients with chronic pain: A meta-analytic review (2022) · cites this paper as Martorella et al., 2017
The Discussion (Principal Findings; page unavailable) reports small, immediate improvements in pain intensity and pain-related disability versus standard care or a waiting list. It reports no statistically significant benefit for anxiety or depression; its finding for catastrophizing is against an active control, not a passive one. The cited results do not establish the claimed benefits for fatigue, pain acceptance, quality of life, or distress. (LLM, conf=0.91)
Experimental — accuracy not yet measuredThe first three IMMPACT outcome domains (pain, physical functioning, emotional functioning) appear frequently reported in meta-analyses on internet-based interventions in chronic pain, whereas the last three (global improvement/satisfaction, disposition/dropout, adverse events) are often not or only partly reported.
“The first three outcome domains appear to be frequently reported in meta-analyses on internet-based interventions in chronic pain, whereas the last three domains related to participant experience and safety of the treatment are often not or only partly reported (Buhrman et al., 2016; Martorella et al., 2017; Vugts et al., 2018).”
From Guided internet-based cognitive-behavioral therapy for patients with chronic pain: A meta-analytic review (2022) · cites this paper as Martorella et al., 2017
The Discussion’s Principal Findings (page not supplied) say the review evaluated pain intensity, pain-related disability, anxiety, depression, and pain catastrophizing, supporting the claim about the first three domains. The Discussion’s Limitations and Future Research section reports attrition rates, so dropout was not wholly unreported; the review does not establish a general reporting pattern across meta-analyses for satisfaction, dropout, and adverse events. (LLM, conf=0.85)
Experimental — accuracy not yet measuredExisting eHealth and mHealth solutions in pain settings have focused mostly on self-administered treatments, mostly psychological or physical therapy.
“To date, the focus of existing eHealth and mHealth solutions in pain settings has been mostly placed on self-administered treatments, mostly of psychological or alternatively of physical therapy nature [64,65,66].”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Study [39] has conflicting publication years
MinorTable 2 labels Moessner study [39] as 2012, while Table 1 labels the same study as 2014.
“| Moessner, 2012 [39] | CBT |”
“| Moessner, 2014 [39] | Germany |”
Studies called higher-dropout have rates above the stated cutoff
MinorThe discussion labels the cited studies as having higher dropout rates of less than 20%, but Table 1 reports 40% for Kristjánsdóttir, 25% for Lorig 2008, and 44% for Moessner 2012.
“among studies with higher dropout rates (<20%), interventions could include up to 5 sessions per week [46,47,58] or could last for 12 to 15 weeks [59].”
“| Kristjánsdóttir, 2013 [46,47] | Norway | 140 | 40 |”
Stated maximum session count is below a listed intervention
MinorThe text says interventions had at most 18 sessions, but Table 2 lists 20 sessions for Kristjánsdóttir.
“The interventions included 5 to 18 sessions over a period of 3 weeks to 12 months”
“5/week (20 sessions)”
Short-term pain confidence interval differs from Table 5
MinorThe text gives an upper confidence limit of -0.0, whereas the corresponding Table 5 total gives -0.07.
“SMD –0.21, 95% CI –0.34 to –0.0, P=.003; I2=29%”
“–0.21 (–0.34 to –0.07)”
Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823 · see citing works
The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
Higgins, J. P. T., Altman, D. G., Gotzsche, P. C., Juni, P., Moher, D., Oxman, A. D., Savovic, J., Schulz, K. F., Weeks, L., Sterne, J. A. C., et al. (2011) · BMJ · doi:10.1136/bmj.d5928 · Cited by 33,817 · see citing works
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000100 · Cited by 28,164 · see citing works
Dermyshi, E., Wang, Y., Yan, C., Hong, W., Qiu, G., Gong, X., & Zhang, T. (2017) · Neonatology · doi:10.1159/000454668 · Cited by 24,577 · see citing works
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gotzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · BMJ · doi:10.1136/bmj.b2700 · Cited by 17,648 · see citing works
Shamseer, L., Moher, D., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., Shekelle, P., Stewart, L. A., & the PRISMA-P Group (2015) · BMJ · doi:10.1136/bmj.g7647 · Cited by 13,120 · see citing works
Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., & Altman, D. G. (2010) · International Journal of Surgery · doi:10.1016/j.ijsu.2010.02.007 · Cited by 12,156 · see citing works
Sterne, J. A. C., Sutton, A. J., Ioannidis, J. P. A., Terrin, N., Jones, D. R., Lau, J., Carpenter, J., Rucker, G., Harbord, R. M., Schmid, C. H., et al. (2011) · BMJ · doi:10.1136/bmj.d4002 · Cited by 7,709 · see citing works
Petty, R. E., & Cacioppo, J. T. (1986) · doi:10.1007/978-1-4612-4964-1 · Cited by 5,219 · see citing works
Core outcome measures for chronic pain clinical trials: IMMPACT recommendations
Dworkin, R. H., Turk, D. C., Farrar, J. T., Haythornthwaite, J. A., Jensen, M. P., Katz, N. P., Kerns, R. D., Stucki, G., Allen, R. R., Bellamy, N., et al. (2005) · Pain · doi:10.1016/j.pain.2004.09.012 · Cited by 3,732 · see citing works
Core outcome domains for chronic pain clinical trials: IMMPACT recommendations
Turk, D. C., Dworkin, R. H., Allen, R. R., Bellamy, N., Brandenburg, N., Carr, D. B., Cleeland, C., Dionne, R., Farrar, J. T., Galer, B. S., et al. (2003) · Pain · doi:10.1016/j.pain.2003.08.001 · Cited by 3,510 · cited 1× · see citing works
“We selected outcomes according to pain clinical trials recommendations [36-38].”
MethodDworkin, R. H., Turk, D. C., Wyrwich, K. W., Beaton, D., Cleeland, C. S., Farrar, J. T., Haythornthwaite, J. A., Jensen, M. P., Kerns, R. D., Ader, D. N., et al. (2008) · The Journal of Pain · doi:10.1016/j.jpain.2007.09.005 · Cited by 3,471 · cited 1× · see citing works
“We selected outcomes according to pain clinical trials recommendations [36-38].”
MethodHjermstad, M. J., Fayers, P. M., Haugen, D. F., Caraceni, A., Hanks, G. W., Loge, J. H., Fainsinger, R., Aass, N., & Kaasa, S. (2011) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2010.08.016 · Cited by 2,697 · see citing works
Webb, T. L., Joseph, J., Yardley, L., & Michie, S. (2010) · Journal of Medical Internet Research · doi:10.2196/jmir.1376 · Cited by 2,517 · see citing works
Petty, R. E., Wegener, D. T., & Fabrigar, L. R. (1997) · Annual Review of Psychology · doi:10.1146/annurev.psych.48.1.609 · Cited by 2,290 · see citing works
Psychological therapies for the management of chronic pain (excluding headache) in adults
Williams, A. C. D. C., Eccleston, C., & Morley, S. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007407.pub3 · Cited by 1,634 · see citing works
International Association for the Study of Pain
Breivik, H. (2002) · Journal of Pain and Symptom Management · doi:10.1016/s0885-3924(02)00465-7 · Cited by 1,222 · see citing works
Pain Management: A Fundamental Human Right
Brennan, F. P., Carr, D. B., & Cousins, M. J. (2007) · Anesthesia & Analgesia · doi:10.1213/01.ane.0000268145.52345.55 · Cited by 999 · see citing works
Wantland, D. J., Portillo, C. J., Holzemer, W. L., Slaughter, R., & McGhee, E. M. (2004) · Journal of Medical Internet Research · doi:10.2196/jmir.6.4.e40 · Cited by 966 · see citing works
Understanding tailoring in communicating about health
Hawkins, R. P., Kreuter, M., Resnicow, K., Fishbein, M., & Dijkstra, A. (2008) · Health Education Research · doi:10.1093/her/cyn004 · Cited by 934 · cited 6× · see citing works
“Experts in health behavior change have shown that conveying health information without considering individual differences may inhibit behavior change [20-26].”
BackgroundMethodInfluentialEstimates of Pain Prevalence and Severity in Adults: United States, 2012
Nahin, R. L. (2015) · The Journal of Pain · doi:10.1016/j.jpain.2015.05.002 · Cited by 918 · see citing works
Ehde, D. M., Dillworth, T. M., & Turner, J. A. (2014) · American Psychologist · doi:10.1037/a0035747 · Cited by 879 · see citing works
Michie, S., Yardley, L., West, R., Patrick, K., & Greaves, F. (2017) · Journal of Medical Internet Research · doi:10.2196/jmir.7126 · Cited by 865 · see citing works
A meta-analysis of computer-tailored interventions for health behavior change
Krebs, P., Prochaska, J. O., & Rossi, J. S. (2010) · Preventive Medicine · doi:10.1016/j.ypmed.2010.06.004 · Cited by 854 · see citing works
Defining Internet-Supported Therapeutic Interventions
Barak, A., Klein, B., & Proudfoot, J. G. (2009) · Annals of Behavioral Medicine · doi:10.1007/s12160-009-9130-7 · Cited by 731 · cited 2× · see citing works
“Here the term Web-based interventions refers to Barak et al’s definition [13]:”
BackgroundMethodA meta-analysis of web-delivered tailored health behavior change interventions
Lustria, M. L. A., Noar, S. M., Cortese, J., Van Stee, S. K., Glueckauf, R. L., & Lee, J. (2013) · Journal of Health Communication · doi:10.1080/10810730.2013.768727 · Cited by 689 · cited 4× · see citing works
“Hence, it has been shown that Web-based tailored interventions that are preventive in nature and targeting a general population, not a specific condition, were more successful [30].”
BackgroundInfluentialTailoring Health Messages: Customizing Communication With Computer Technology
Farrell, D. W., Rimer, B. K., Olevitch, L. R., Brennan, L. K., & Kreuter, M. W. (1999) · Cited by 635 · see citing works
Acceptance and commitment therapy and mindfulness for chronic pain: Model, process, and progress.
McCracken, L. M., & Vowles, K. E. (2014) · American Psychologist · doi:10.1037/a0035623 · Cited by 627 · see citing works
Computer-tailored health interventions delivered over the web: Review and analysis of key components
Lustria, M. L. A., Cortese, J., Noar, S. M., & Glueckauf, R. L. (2009) · Patient Education and Counseling · doi:10.1016/j.pec.2008.08.023 · Cited by 566 · see citing works
Advancing Tailored Health Communication: A Persuasion and Message Effects Perspective
Rimer, B. K., & Kreuter, M. W. (2006) · Journal of Communication · doi:10.1111/j.1460-2466.2006.00289.x · Cited by 531 · see citing works
Internet-Based Chronic Disease Self-Management: A Randomized Trial
Lorig, K. R., Ritter, P. L., Laurent, D. D., & Plant, K. (2006) · Medical Care · doi:10.1097/01.mlr.0000233678.80203.c1 · Cited by 450 · see citing works
Lorig, K. R., Ritter, P. L., Laurent, D. D., & Plant, K. (2008) · Arthritis Care & Research · doi:10.1002/art.23817 · Cited by 440 · see citing works
Kreuter, M. W. (2000) · Health Education Research · doi:10.1093/her/15.1.1 · Cited by 414 · see citing works
Recommendations by Cochrane Review Groups for assessment of the risk of bias in studies
Lundh, A., & Gøtzsche, P. C. (2008) · BMC Medical Research Methodology · doi:10.1186/1471-2288-8-22 · Cited by 352 · see citing works
Savović, J., Weeks, L., Sterne, J. A., Turner, L., Altman, D. G., Moher, D., & Higgins, J. P. (2014) · Systematic Reviews · doi:10.1186/2046-4053-3-37 · Cited by 340 · see citing works
Macea, D. D., Gajos, K., Daglia Calil, Y. A., & Fregni, F. (2010) · The Journal of Pain · doi:10.1016/j.jpain.2010.06.005 · Cited by 289 · see citing works
Psychological therapies (Internet-delivered) for the management of chronic pain in adults
Eccleston, C., Fisher, E., Craig, L., Duggan, G. B., Rosser, B. A., & Keogh, E. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010152.pub2 · Cited by 271 · cited 14× · see citing works
“Previous authors [18] have suggested including participants with moderate to severe pain intensity at baseline in order to appreciate the benefits of these interventions.”
BackgroundResultInfluentialA controlled trial of self-help treatment of recurrent headache conducted via the Internet.
Ström, L., Pettersson, R., & Andersson, G. (2000) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.68.4.722 · Cited by 267 · cited 19× · see citing works
“Regarding selection bias, randomized sequence generation presented an unclear risk for about half of the studies (n=9) [39,48,53,56-61] and a low risk of bias for the other half (n=8).”
BackgroundMethodInfluentialControlled trial of Internet-based treatment with telephone support for chronic back pain
Buhrman, M., Fältenhag, S., Ström, L., & Andersson, G. (2004) · Pain · doi:10.1016/j.pain.2004.07.021 · Cited by 232 · see citing works
Can pain be managed through the Internet? A systematic review of randomized controlled trials
Bender, J. L., Radhakrishnan, A., Diorio, C., Englesakis, M., & Jadad, A. R. (2011) · Pain · doi:10.1016/j.pain.2011.02.012 · Cited by 223 · see citing works
Internet interventions for chronic pain including headache: a systematic review
Buhrman, M., Gordh, T., & Andersson, G. (2016) · Internet Interventions · doi:10.1016/j.invent.2015.12.001 · Cited by 223 · see citing works
Pain relief: a universal human right
Cousins, M. J., Brennan, F. P., & Carr, D. B. (2004) · Pain · doi:10.1016/j.pain.2004.09.002 · Cited by 207 · see citing works
Working mechanisms of computer-tailored health education: evidence from smoking cessation
Dijkstra, A. (2005) · Health Education Research · doi:10.1093/her/cyh014 · Cited by 193 · see citing works
Bossen, D., Veenhof, C., Beek, K. E. V., Spreeuwenberg, P. M. M., Dekker, J., & de Bakker, D. H. (2013) · Journal of Medical Internet Research · doi:10.2196/jmir.2662 · Cited by 193 · see citing works
Dear (2015) · doi:10.1097/j.pain.0000000000000251 · Cited by 187 · see citing works
Dear, B. F., Titov, N., Perry, K. N., Johnston, L., Wootton, B. M., Terides, M. D., Rapee, R. M., & Hudson, J. L. (2013) · Pain · doi:10.1016/j.pain.2013.03.005 · Cited by 182 · see citing works
Chronic pain and sex-differences; women accept and move, while men feel blue
Rovner, G. S., Sunnerhagen, K. S., Björkdahl, A., Gerdle, B., Börsbo, B., Johansson, F., & Gillanders, D. (2017) · PLOS ONE · doi:10.1371/journal.pone.0175737 · Cited by 179 · see citing works
Kristjánsdóttir, Ó. B., Fors, E. A., Eide, E., Finset, A., Stensrud, T. L., van Dulmen, S., Wigers, S. H., & Eide, H. (2013) · Journal of Medical Internet Research · doi:10.2196/jmir.2249 · Cited by 176 · see citing works
An Online Self-help CBT Intervention for Chronic Lower Back Pain
Carpenter, K. M., Stoner, S. A., Mundt, J. M., & Stoelb, B. (2012) · The Clinical Journal of Pain · doi:10.1097/ajp.0b013e31822363db · Cited by 157 · see citing works
Perspectives on Persuasion, Social Influence, and Compliance Gaining
Seiter, J. S., & Gass, R. H. (2003) · Digital Commons - USU (Utah State University) · Cited by 156 · see citing works
Carnes, D., Homer, K. E., Miles, C. L., Pincus, T., Underwood, M., Rahman, A., & Taylor, S. J. C. (2012) · The Clinical Journal of Pain · doi:10.1097/ajp.0b013e31822ed2f3 · Cited by 141 · see citing works
Internet‐Based Treatment of Headache: Does Telephone Contact Add Anything?
Andersson, G., Lundström, P., & Ström, L. (2003) · Headache: The Journal of Head and Face Pain · doi:10.1046/j.1526-4610.2003.03070.x · Cited by 136 · see citing works
e-Health and chronic pain management: Current status and developments
Keogh, E., Rosser, B. A., & Eccleston, C. (2010) · Pain · doi:10.1016/j.pain.2010.07.014 · Cited by 132 · see citing works
painACTION-Back Pain: A Self-Management Website for People with Chronic Back Pain
Chiauzzi, E., Pujol, L. A., Wood, M., Bond, K., Black, R., Yiu, E., & Zacharoff, K. (2010) · Pain Medicine · doi:10.1111/j.1526-4637.2010.00879.x · Cited by 130 · see citing works
van Boekel, R. L. M., Vissers, K. C. P., van der Sande, R., Bronkhorst, E. M., Lerou, J. G. C., & Steegers, M. A. H. (2017) · PLoS ONE · doi:10.1371/journal.pone.0177345 · Cited by 129 · see citing works
Web-Based Interventions for Chronic Back Pain: A Systematic Review
Garg, S., Garg, D., Turin, T. C., & Chowdhury, M. F. U. (2016) · Journal of Medical Internet Research · doi:10.2196/jmir.4932 · Cited by 115 · see citing works
Krein, S. L., Kadri, R., Hughes, M. V., Kerr, E. A., Piette, J. D., Holleman, R. G., Kim, H. M., & Richardson, C. R. (2013) · Journal of Medical Internet Research · doi:10.2196/jmir.2605 · Cited by 108 · see citing works
Leveille, S. G., Huang, A., Tsai, S. B., Allen, M., Weingart, S. N., & Iezzoni, L. I. (2009) · Medical Care · doi:10.1097/mlr.0b013e3181844dd0 · Cited by 89 · see citing works
Systematic review of multidisciplinary chronic pain treatment facilities
Fashler, S. R., Cooper, L. K., Oosenbrug, E. D., Burns, L. C., Razavi, S., Goldberg, L., & Katz, J. (2016) · Pain Research and Management · doi:10.1155/2016/5960987 · Cited by 88 · see citing works
RAHelp: an online intervention for individuals with rheumatoid arthritis
Shigaki, C. L., Smarr, K. L., Siva, C., Ge, B., Musser, D., & Johnson, R. (2013) · Arthritis Care & Research · doi:10.1002/acr.22042 · Cited by 86 · see citing works
Kristjánsdóttir, Ó. B., Fors, E. A., Eide, E., Finset, A., Stensrud, T. L., van Dulmen, S., Wigers, S. H., & Eide, H. (2013) · Journal of Medical Internet Research · doi:10.2196/jmir.2442 · Cited by 78 · see citing works
Martorella, G., Côté, J., Racine, M., & Choinière, M. (2012) · Journal of Medical Internet Research · doi:10.2196/jmir.2070 · Cited by 65 · see citing works
Self-citationInternet-Based Aftercare for Patients with Back Pain—A Pilot Study
Moessner, M., Schiltenwolf, M., & Neubauer, E. (2012) · Telemedicine and e-Health · doi:10.1089/tmj.2011.0221 · Cited by 33 · see citing works
Web-Based Behavioral Interventions for the Management of Chronic Pain
Williams, D. A. (2011) · Current Rheumatology Reports · doi:10.1007/s11926-011-0212-8 · Cited by 29 · see citing works
Moessner, M., Aufdermauer, N., Baier, C., Göbel, H., Kuhnt, O., Neubauer, E., Poesthorst, H., & Kordy, H. (2013) · PPmP - Psychotherapie · Psychosomatik · Medizinische Psychologie · doi:10.1055/s-0033-1351266 · Cited by 23 · see citing works
Ashraf, E. M. (2015) · Journal of Public Health and Epidemiology · doi:10.5897/jphe2014.0702 · Cited by 14 · see citing works
The effect of tailored Web-based interventions on pain in adults: a systematic review protocol
Martorella, G., Gélinas, C., Bérubé, M., Boitor, M., Fredericks, S., & LeMay, S. (2016) · Systematic Reviews · doi:10.1186/s13643-016-0233-5 · Cited by 5 · see citing works
Self-citation
Flagged first, then by citations
Research works printed but not linked: 3
- 2011, Relieving Pain in America: A Blueprint for Transforming Prevention, Care, Education and Research
- The Cochrane CollaborationRevMan: computer program version 5.320142017-08-30Copenhagen, DenmarkThe Nordic Cochrane Centrehttp://community.cochrane.org/tools/review-production-tools/revman-5
- Sterne, J, 2008, Cochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series
Cited by
Sorted by citations
Eccleston, C., Blyth, F. M., Dear, B. F., Fisher, E. A., Keefe, F. J., Lynch, M. E., Palermo, T. M., Reid, M. C., & Williams, A. C. D. C. (2020) · Pain · doi:10.1097/j.pain.0000000000001885 · Cited by 480 · see citing works
The efficacy of e-health in the self-management of chronic low back pain: A meta analysis
Du, S., Liu, W., Cai, S., Hu, Y., & Dong, J. (2019) · International Journal of Nursing Studies · doi:10.1016/j.ijnurstu.2019.103507 · Cited by 195 · see citing works
The social threats of COVID-19 for people with chronic pain
Karos, K., McParland, J. L., Bunzli, S., Devan, H., Hirsh, A., Kapos, F. P., Keogh, E., Moore, D., Tracy, L. M., & Ashton-James, C. E. (2020) · Pain · doi:10.1097/j.pain.0000000000002004 · Cited by 149 · see citing works
Impact of COVID-19 pandemic on chronic pain management: Looking for the best way to deliver care
Puntillo, F., Giglio, M., Brienza, N., Viswanath, O., Urits, I., Kaye, A. D., Pergolizzi, J. V., Paladini, A., & Varrassi, G. (2020) · Best practice & research. Clinical anaesthesiology · doi:10.1016/j.bpa.2020.07.001 · Cited by 102 · see citing works
Moman, R. N., Dvorkin, J., Pollard, E. M., Wanderman, R., Murad, M. H., Warner, D. O., & Hooten, W. M. (2019) · Pain Medicine · doi:10.1093/pm/pnz164 · Cited by 93 · see citing works
McCracken, L. M. (2023) · European Journal of Pain · doi:10.1002/ejp.2091 · Cited by 81 · see citing works
Benefits of Mobile Apps for Cancer Pain Management: Systematic Review
Zheng, C., Chen, X., Weng, L., Guo, L., Xu, H., Lin, M., Xue, Y., Lin, X., Yang, A., Yu, L., et al. (2020) · JMIR mHealth and uHealth · doi:10.2196/17055 · Cited by 69 · see citing works
Fernandes, L. G., Oliveira, R. F. F., Marinelli, P., Fagundes, F. R. C., Soares, R. J., & Saragiotto, B. T. (2022) · Brazilian Journal of Physical Therapy · doi:10.1016/j.bjpt.2022.100464 · Cited by 62 · see citing works
Atreya, S. Y., Kumar, G., Samal, J., Bhattacharya, M., Banerjee, S., Mallick, P., Chakraborty, D., Gupta, S., & Sarkar, S. (2020) · Indian Journal of Palliative Care · doi:10.4103/ijpc.ijpc_145_20 · Cited by 51 · see citing works
Mauck, M. C., Aylward, A. F., Barton, C. E., Birckhead, B., Carey, T., Dalton, D. M., Fields, A. J., Fritz, J., Hassett, A. L., Hoffmeyer, A., et al. (2022) · PAIN Reports · doi:10.1097/pr9.0000000000001019 · Cited by 49 · see citing works
Fritz, J. M., Davis, A. F., Burgess, D. J., Coleman, B. C., Cook, C. E., Farrokhi, S., Goertz, C., Heapy, A. A., Lisi, A. J., McGeary, D. D., et al. (2020) · Pain · doi:10.1097/j.pain.0000000000002139 · Cited by 40 · see citing works
Terpstra, J. A., van der Vaart, R., van Beugen, S., van Eersel, R. A., Gkika, I., Erdős, D., Schmidt, J., Radstake, C., Kloppenburg, M., van Middendorp, H., et al. (2022) · Internet Interventions · doi:10.1016/j.invent.2022.100587 · Cited by 38 · see citing works
Birckhead, B. J., Eberlein, S. A., Alvarez, G., Gale, R., Dupuy, T. P., Makaroff, K. E., Fuller, G., Liu, X., Yu, K., Black, J. T., et al. (2021) · BMJ Open · doi:10.1136/bmjopen-2021-050545 · Cited by 37 · see citing works
Suso-Ribera, C., Castilla, D., Zaragozá, I., Mesas, Á., Server, A., Medel, J., & García-Palacios, A. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17186568 · Cited by 38 · see citing works
Bendelin, N., Björkdahl, P., Risell, M., Nelson, K. Z., Gerdle, B., Andersson, G., & Buhrman, M. (2020) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-020-03198-1 · Cited by 33 · see citing works
“[38], a growing knowledge suggests that adjusted treatment might be necessary for self-managing pain over time [21].”
BackgroundPain relief in the palm of your hand: Harnessing mobile health to manage pediatric pain
Hunter, J. F., Kain, Z. N., & Fortier, M. A. (2018) · Pediatric Anesthesia · doi:10.1111/pan.13547 · Cited by 32 · see citing works
Telerehabilitation for musculoskeletal pain – An overview of systematic reviews
Vieira, L. M. S. M. D. A., Andrade, M. A., & Sato, T. D. O. (2023) · Digital Health · doi:10.1177/20552076231164242 · Cited by 31 · see citing works
Pain management programmes via video conferencing: a rapid review
Walumbe, J., Belton, J., & Denneny, D. (2021) · Scandinavian Journal of Pain · doi:10.1515/sjpain-2020-0112 · Cited by 29 · see citing works
Telehealth and Online Cognitive Behavioral Therapy–Based Treatments for High-Impact Chronic Pain
DeBar, L., Mayhew, M., Wellman, R., Balderson, B. H. K., Dickerson, J. F., Elder, C. R., Justice, M., Keefe, F. J., McMullen, C. K., Owen‐Smith, A. A., et al. (2025) · JAMA · doi:10.1001/jama.2025.11178 · Cited by 30 · see citing works
Fernandes, L. G., Devan, H., Kamper, S. J., Williams, C. M., & Saragiotto, B. T. (2020) · Systematic Reviews · doi:10.1186/s13643-020-01390-x · Cited by 23 · see citing works
Teo, C. H., Ng, C. J., Lo, S. K., Lim, C. D., & White, A. (2019) · JMIR mhealth and uhealth · doi:10.2196/10216 · Cited by 23 · see citing works
Characteristics of Nonpharmacological Interventions for Pain Management in the ICU: A Scoping Review
Martorella, G. (2019) · AACN Advanced Critical Care · doi:10.4037/aacnacc2019281 · Cited by 23 · see citing works
Self-citationTransition from Acute to Chronic Pain: Where Cells, Systems and Society Meet
Glare, P., Overton, S., & Aubrey, K. (2020) · Pain Management · doi:10.2217/pmt-2019-0039 · Cited by 20 · see citing works
Dhillon, K. H., Manji, J., Tapia, M., Prasad, J., Kleid, S. M., Flatman, S., Nguyen, K., McLean, T., & Magarey, M. J. R. (2022) · ANZ Journal of Surgery · doi:10.1111/ans.17722 · Cited by 21 · see citing works
Mayhew, M., Balderson, B. H. K., Cook, A. J., Dickerson, J. F., Elder, C. R., Firemark, A. J., Haller, I. V., Justice, M., Keefe, F. J., McMullen, C. K., et al. (2023) · Trials · doi:10.1186/s13063-023-07165-8 · Cited by 20 · see citing works
Cheng, D. K., Lai, K. S. P., Pico-Espinosa, O. J., Rice, D., Chung, C. L. R., Modarresi, G., & Sud, A. (2021) · Pain medicine (Malden, Mass.) · doi:10.1093/pm/pnab248 · Cited by 15 · see citing works
Shade, M. Y., Yan, C., Jones, V. K., & Boron, J. A. B. (2024) · JMIR Formative Research · doi:10.2196/64763 · Cited by 20 · see citing works
Adhikari, S. D., Biswàs, S., Mishra, S., Kumar, V., Bharati, S. J., Gupta, N., Garg, R. K., & Bhatnagar, S. (2021) · Indian Journal of Palliative Care · doi:10.25259/ijpc_45_21 · Cited by 20 · see citing works
Martorella, G., Graven, L. J., Schluck, G., Berube, M., & Gélinas, C. (2018) · SAGE Open Nursing · doi:10.1177/2377960818806270 · Cited by 16 · see citing works
Self-citationMackey, L. M., Blake, C. M., Squiers, L., Casey, M., Power, C. K., Victory, R., Hearty, C., & Fullen, B. M. (2019) · Musculoskeletal Care · doi:10.1002/msc.1386 · Cited by 16 · see citing works
Doorley, J. D., Greenberg, J., Stauder, M. J., & Vranceanu, A. (2021) · Mindfulness · doi:10.1007/s12671-021-01729-y · Cited by 15 · see citing works
Occupational e-Mental Health – eine Übersicht zu Ansätzen, Evidenz und Implementierung
Lehr, D., & Boß, L. (2019) · Springer eBooks · doi:10.1007/978-3-662-59044-7_11 · Cited by 14 · see citing works
Lazaridou, A., Paschali, M., Vilsmark, E. S., Wilkins, T., Napadow, V., & Edwards, R. R. (2022) · BMC Women s Health · doi:10.1186/s12905-022-01840-9 · Cited by 12 · see citing works
Non-pharmacological management of neuropathic pain in older adults: a systematic review
Holmes, A., & Chang, Y. (2023) · Pain Medicine · doi:10.1093/pm/pnad112 · Cited by 11 · see citing works
Brown, J., Doherty, D., Claus, A. P., Gilbert, K., & Nielsen, M. (2021) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2021.10.018 · Cited by 11 · see citing works
Goudman, L., Smedt, A. D., Huygens, R., Noppen, M. M. P., Vanschoenwinkel, M., Hatem, S. M., & Moens, M. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10225353 · Cited by 11 · see citing works
Berube, M., Verret, M., Bourque, L., Côté, C. L., Guénette, L., Richard‐Denis, A., Ouellet, S., Singer, L. N., Gauthier, L. R., Gagnon, M., et al. (2024) · Pain · doi:10.1097/j.pain.0000000000003288 · Cited by 10 · see citing works
Self-citationScholten, S., & Glombiewski, J. A. (2024) · Current Opinion in Psychology · doi:10.1016/j.copsyc.2024.101958 · Cited by 10 · see citing works
Martorella, G., Hanley, A. W., Pickett, S. M., & Gélinas, C. (2021) · JMIR Research Protocols · doi:10.2196/30951 · Cited by 16 · see citing works
Self-citationReilly, E. D., Kathawalla, U., Robins, H., Heapy, A. A., Hogan, T. P., Waring, M. E., Quigley, K. S., Drebing, C. E., Bickmore, T., Volonte, M., et al. (2023) · JMIR Research Protocols · doi:10.2196/45887 · Cited by 9 · see citing works
Oirschot, G. V., Pomphrey, A., Dunne, C., Murphy, K., Blood, K., & Doherty, C. (2024) · JMIR Rehabilitation and Assistive Technologies · doi:10.2196/48154 · Cited by 8 · see citing works
Reilly, E. D., Kelly, M. M., Grigorian, H. L., Waring, M. E., Quigley, K. S., Hogan, T. P., Heapy, A. A., Drebing, C. E., Volonte, M., Kathawalla, U., et al. (2024) · JMIR Formative Research · doi:10.2196/56437 · Cited by 9 · see citing works
Hayashi, K., Miki, K., Shiro, Y., Tetsunaga, T., Takasusuki, T., Hosoi, M., & Yukioka, M. (2025) · Scientific Reports · doi:10.1038/s41598-024-85056-x · Cited by 9 · see citing works
Effectiveness of tailored interventions on quality of life in cancer survivors: A systematic review
Lee, Y., Choi, G. W., & Kim, B. (2025) · Patient Education and Counseling · doi:10.1016/j.pec.2025.108674 · Cited by 10 · see citing works
Engagement in Digital Self-management Interventions for Chronic Pain
MacLean, R. R., Shor, R., Reilly, E. D., Reuman, L., Solar, C. A., Halat, A. M., & Higgins, D. M. (2025) · Clinical Journal of Pain · doi:10.1097/ajp.0000000000001289 · Cited by 11 · see citing works
Berube, M., Gélinas, C., Feeley, N., Martorella, G., Côté, J., Laflamme, G. Y., Rouleau, D. M., & Choinière, M. (2018) · JMIR Formative Research · doi:10.2196/10323 · Cited by 9 · see citing works
Self-citationSim, A., McNeilage, A. G., Gholamrezaei, A., Rebbeck, T., & Ashton-James, C. (2024) · BMJ Open · doi:10.1136/bmjopen-2024-085778 · Cited by 8 · see citing works
Martorella, G., Hanley, A. W., Tong, H., Miao, H., Worts, P. R., Bellamy, D., & Ahn, H. B. (2024) · Mindfulness · doi:10.1007/s12671-024-02329-2 · Cited by 7 · see citing works
Self-citationWildemeersch, D., D’Hondt, M., Bernaerts, L., Mertens, P., Saldien, V., Hendriks, J. M., Walcarius, A.-S., Sterkens, L., & Hans, G. H. (2018) · JMIR Perioperative Medicine · doi:10.2196/10996 · Cited by 8 · see citing works
Croon, R. D., Bezabih, A. M., Geuens, J., Wildemeersch, D., Oeyen, D., Verbert, K., & Abeele, V. V. (2019) · IEEE International Conference on Healthcare Informatics (ICHI) · doi:10.1109/ichi.2019.8904661 · Cited by 7 · see citing works
Technological Interventions for Pain Management
Suso-Ribera, C., Castilla, D., Martínez-Borba, V., Jaén, I., Botella, C., Baños, R. M., & García-Palacios, A. (2022) · Comprehensive Clinical Psychology · doi:10.1016/b978-0-12-818697-8.00009-1 · Cited by 6 · see citing works
Interactive AI Routines for Pain Symptoms and Loneliness in Older Adults
Shade, M. Y., Yan, C., Jones, V. K., & Boron, J. B. (2025) · Pain Management Nursing · doi:10.1016/j.pmn.2025.04.003 · Cited by 7 · see citing works
Janevic, M. R., Murnane, E. L., Fillingim, R. B., Kerns, R. D., & Reid, M. C. (2023) · Psychosomatic Medicine · doi:10.1097/psy.0000000000001200 · Cited by 6 · see citing works
Li, L. W., Yi, T. H., & Khaing, N. E. E. (2024) · BMC Digital Health · doi:10.1186/s44247-024-00073-0 · Cited by 5 · see citing works
Reuman, L., Solar, C. A., MacLean, R. R., Halat, A. M., Rajeevan, H., Williams, D. A., Heapy, A. A., Bair, M. J., Krein, S. L., Kerns, R. D., et al. (2022) · Translational Behavioral Medicine · doi:10.1093/tbm/ibab165 · Cited by 5 · see citing works
Greenberg, J., Singh, T., Popok, P., Kulich, R. J., & Vranceanu, A. (2021) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2020.0499 · Cited by 5 · see citing works
Villar-Alises, O., García‐Muñoz, C., Matias-Soto, J., & Martínez-Calderón, J. (2024) · Journal of Orthopaedic and Sports Physical Therapy · doi:10.2519/jospt.2024.12844 · Cited by 4 · see citing works
Gupta, A. K., Paul, S., Soni, A., Kumar, P., Nath, B., & Jotdar, A. (2021) · International Journal of Community Medicine and Public Health · doi:10.18203/2394-6040.ijcmph20211785 · Cited by 4 · see citing works
Bendelin, N., Gerdle, B. U. C., & Andersson, G. (2023) · Scandinavian Journal of Pain · doi:10.1515/sjpain-2022-0139 · Cited by 4 · see citing works
Telerehabilitation for neck pain
Fandim, J. V., de Oliveira, L. A., Yamato, T. P., Kamper, S. J., Costa, L. O. P., Maher, C. G., & Saragiotto, B. T. (2025) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd014428.pub2 · Cited by 3 · see citing works
Lee, J. W. K., Mowat, R. M., Blamires, J., & Foster, M. (2025) · Journal of Advanced Nursing · doi:10.1111/jan.16716 · Cited by 3 · see citing works
Berube, M., Verret, M., Martorella, G., Gagnon, M., Bourque, L., Déry, M.-P., Hudon, A., Singer, L. N., Richard‐Denis, A., Ouellet, S., et al. (2023) · JBI Evidence Synthesis · doi:10.11124/jbies-22-00298 · Cited by 3 · see citing works
Self-citationHe, J., Tse, M. Y. M., Kwok, T. T.-O., Wu, T. C. M., & Tang, S. (2025) · Healthcare · doi:10.3390/healthcare13030289 · Cited by 3 · see citing works
Shi, C., Zhang, T., Du, X., Lu, S., & Witthöft, M. (2024) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2024.02.001 · Cited by 2 · see citing works
Identifying chronic pain subgroups in the UK biobank for persona development: A clustering analysis
Hsu, T. C., Whelan, P., Armitage, C. J., & McBeth, J. (2025) · Digital Health · doi:10.1177/20552076251333497 · Cited by 2 · see citing works
Mailis, A., Ang, S. B., Renna, T. D., Kazatsker, M. M., MacGregor, E. A., Misasi, G., Poli, J. G., Simoncini, T., Wolfman, W., & Nappi, R. E. (2026) · Climacteric · doi:10.1080/13697137.2026.2722558 · Cited by 2 · see citing works
Mauck, M. C., Aylward, A. F., Barton, C. E., Birckhead, B. J., Carey, T. S., Dalton, D. M., Fields, A. J., Fritz, J. M., Hassett, A. L., Hoffmeyer, A., et al. (2024) · Der Schmerz · doi:10.1007/s00482-024-00798-x · Cited by 2 · see citing works
The use of an E-pain technology in the management of chronic pain. Case report
Lima, L. D. O., & dos Reis, F. J. J. (2018) · Brazilian Journal Of Pain · doi:10.5935/2595-0118.20180036 · Cited by 2 · see citing works
Odake, Y., Fukutani, N., Shimoura, K., Morino, T., Matsumura, N., Niu, Q., Shinohara, Y., Mukaiyama, K., Nagai‐Tanima, M., & Aoyama, T. (2021) · Environmental and Occupational Health Practice · doi:10.1539/eohp.2020-0024-oa · Cited by 2 · see citing works
A Review of the Design of Multimedia Patient Educational Materials in Low Back Pain Research
Oirschot, G. V., & Doherty, C. (2024) · Physical Therapy Research · doi:10.1298/ptr.r0032 · Cited by 2 · see citing works
Ristau, J., Okobi, A., Miller, M. J., Cheng, J., Deviren, S., Schwarz, E. B., Fairchild, T., Tsoh, J. Y., Aguilera, A., Zheng-Huang, C. J., et al. (2026) · Trials · doi:10.1186/s13063-025-09402-8 · Cited by 1 · see citing works
Trò, R., Orecchia, A., Disma, N. M., Uva, P., Cavanna, R., Zanardi, N., Torre, M., & Fato, M. (2024) · JMIR Formative Research · doi:10.2196/56674 · Cited by 1 · see citing works
Pyke, R. E. (2018) · Sexual Medicine Reviews · doi:10.1016/j.sxmr.2018.07.002 · Cited by 1 · see citing works
Senior WISE intervention: Gender differences in bodily pain and trait anxiety
McDougall, G. J., Pituch, K. A., Martorella, G., & Monroe, T. B. (2021) · Archives of Psychiatric Nursing · doi:10.1016/j.apnu.2021.05.001
Self-citationTackling pain after cardiac surgery: It takes a village!
Martorella, G. (2021) · International Health Trends and Perspectives · doi:10.32920/ihtp.v1i2.1449
Self-citationNew coping strategies and self-education for chronic pain management: E-health
Pardo, V. M., San‐Antolín, M., López‐López, D., Vallejo, R., Losa‐Iglesias, M. E., Morales, C. R., Rodríguez‐Sanz, D., Martínez‐Jiménez, E. M., & Calvo‐Lobo, C. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820237-1.00052-1
Telerehabilitation for Pain Management
Kurz, J., & Hussey, D. K. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-82486-6.00013-7
Berube, M., Gélinas, C., Feeley, N., Martorella, G., Côté, J., Laflamme, G. Y., Rouleau, D. M., & Choinière, M. (2018) · doi:10.2196/preprints.10323
Self-citationBerube, M., Gélinas, C., Feeley, N., Martorella, G., C�t�, J., Laflamme, G. Y., Rouleau, D. M., & Choinière, M. (2018) · doi:10.2196/preprints.10323.a
Self-citationBendelin, N. (2023) · Linköping University medical dissertations · doi:10.3384/9789180750288
Eriksson‐Liebon, M. (2024) · Linköping University medical dissertations · doi:10.3384/9789180755597
Singla, A. K., Khosla, D., Kumar, D., Madan, R., Goyal, S., Kumar, N., & Kapoor, R. K. (2024) · PubMed Central · doi:10.60787/nmj-63-1-132
Evaluating Older Adults’ Engagement and Usability with AI Driven Interventions (Preprint)Preprint
Shade, M. Y., Yan, C., Jones, V., & Boron, J. A. B. (2024) · doi:10.2196/preprints.64763
Chew, M. T., İlhan, E., Dennis, S. M., Nicholson, L. L., Kobayashi, S., & Chan, C. L. (2025) · Health Expectations · doi:10.1111/hex.70186
Lazaridou, A., Paschali, M., Vilsmark, E. S., Wilkins, T., Napadow, V., & Edwards, R. (2022) · Figshare · doi:10.6084/m9.figshare.20208460
LIANG, L.-B., Zhao, H.-Y., Cao, H., Wang, L.-H., Shi, M.-R., Wang, S., Wu, C., & Li, K.-P. (2026) · BMC Health Services Research · doi:10.1186/s12913-026-14539-6
Reilly, E. D., Mueller, L. N., Crossman, D. M., Grigorian, H. L., Schrader, S. W., Kelly, M. M., Bernice, K., & Ellison, M. L. (2026) · JMIR Formative Research · doi:10.2196/93871
Geßner, J., Strobl, E., Gross, C. H., & Weise, C. (2026) · Research Square · doi:10.21203/rs.3.rs-10801339/v1
- Authors
- Martorella, G., Boitor, M., Berube, M., Fredericks, S., Le May, S., & Gélinas, C.
- Affiliations
- Toronto Metropolitan University (CA)
- Jewish General Hospital (CA)
- ORCID
- Venue
- Journal of Medical Internet Research
- Publisher
- JMIR Publications Inc.
- Published
- 2017-11-10
- Volume
- 19
- Issue
- 11
- Pages
- e385
- ISSN
- 1438-8871 (ISSN-L)
- PMC
- PMC5701966
- OpenAlex
- W2767214959
- Semantic Scholar
- 7c0046537c030c80c9c4c3fd55fd61289c8bc204
- Cited by
- 88
- References
- 67
- Citations by year
- 2026: 5 · 2025: 10 · 2024: 16 · 2023: 9 · 2022: 8 · 2021: 13 · 2020: 11 · 2019: 8 · 2018: 8
- FWCI
- 0.86
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Journal of Medical Internet Research (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric Pain Management Techniques
- Keywords
- pain management, chronic pain, pain intensity, pain-related disability, pain catastrophizing, anxiety, depression, physical function, psychological functioning, e-health, personalized interventions
- MeSH terms
- Adult, Female, Humans, Male, Internet, Pain Management
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-09.
Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-09.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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