Cited by 28Digital Mental Health InterventionsArtificial Intelligence in Healthcare and EducationAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

A novel cognitive behavioral therapy–based generative AI tool (Socrates 2.0) to facilitate Socratic dialogue: protocol for a mixed methods feasibility study

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Held, Philip, Pridgen, Sarah A, Chen, Yaozhong, Akhtar, Zuhaib, Amin, Darpan, Pohorence, Sean·2024·JMIR Research Protocols

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Abstract

BACKGROUND: Digital mental health tools, designed to augment traditional mental health treatments, are becoming increasingly important due to a wide range of barriers to accessing mental health care, including a growing shortage of clinicians. Most existing tools use rule-based algorithms, often leading to interactions that feel unnatural compared with human therapists. Large language models (LLMs) offer a solution for the development of more natural, engaging digital tools. In this paper, we detail the development of Socrates 2.0, which was designed to engage users in Socratic dialogue surrounding unrealistic or unhelpful beliefs, a core technique in cognitive behavioral therapies. The multiagent LLM-based tool features an artificial intelligence (AI) therapist, Socrates, which receives automated feedback from an AI supervisor and an AI rater. The combination of multiple agents appeared to help address common LLM issues such as looping, and it improved the overall dialogue experience. Initial user feedback from individuals with lived experiences of mental health problems as well as cognitive behavioral therapists has been positive. Moreover, tests in approximately 500 scenarios showed that Socrates 2.0 engaged in harmful responses in under 1% of cases, with the AI supervisor promptly correcting the dialogue each time. However, formal feasibility studies with potential end users are needed. OBJECTIVE: This mixed methods study examines the feasibility of Socrates 2.0. METHODS: On the basis of the initial data, we devised a formal feasibility study of Socrates 2.0 to gather qualitative and quantitative data about users' and clinicians' experience of interacting with the tool. Using a mixed method approach, the goal is to gather feasibility and acceptability data from 100 users and 50 clinicians to inform the eventual implementation of generative AI tools, such as Socrates 2.0, in mental health treatment. We designed this study to better understand how users and clinicians interact with the tool, including the frequency, length, and time of interactions, users' satisfaction with the tool overall, quality of each dialogue and individual responses, as well as ways in which the tool should be improved before it is used in efficacy trials. Descriptive and inferential analyses will be performed on data from validated usability measures. Thematic analysis will be performed on the qualitative data. RESULTS: Recruitment will begin in February 2024 and is expected to conclude by February 2025. As of September 25, 2024, overall, 55 participants have been recruited. CONCLUSIONS: The development of Socrates 2.0 and the outlined feasibility study are important first steps in applying generative AI to mental health treatment delivery and lay the foundation for formal feasibility studies. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/58195.

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  • Compared to an earlier single-agent version, the addition of two supervisory AI agents appears to improve dialogue quality by reducing redundant, off-topic, overly lengthy answers and repetitive conversational loops.

    “Compared to an earlier single-agent version of the tool, the addition of the 2 supervisory AI agents appears to improve dialogue quality by reducing the risk of redundant, off-topic, or overly lengthy answers and repetitive conversational loops (ie, segments in which similar questions or statements are repeated without progressing the dialogue) [13].”

    From AI-Facilitated Cognitive Reappraisal via Socrates 2.0: Mixed Methods Feasibility Study. (2025) · cites this paper as [13]

    The Introduction’s “Socrates 1.0” section describes the earlier single-agent tool as verbose, prone to getting off task, and caught in conversational loops. The “Socrates 2.0” section says the added agents appeared to improve dialogue quality and reduce looping, with supervisor feedback helping keep conversations focused. Our copy does not establish that the added agents reduced redundant or overly lengthy answers specifically. (LLM, conf=0.84)

    Experimental — accuracy not yet measured
  • LLM-based digital tools that emulate therapists' Socratic dialogue style may be more engaging than static worksheets and thereby increase adherence to out-of-session practice and help users engage in cognitive reappraisal exercises.

    “LLM-based digital tools that emulate therapists’ Socratic dialogue style may be more engaging than static worksheets and thereby increase adherence to out-of-session practice and ultimately help users engage in cognitive reappraisal exercises [13].”

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Authors
Held, P., Pridgen, S. A., Chen, Y., Akhtar, Z., Amin, D., & Pohorence, S.
Affiliations
Rush University Medical Center (US)
Corresponding author
Held, Philip
Venue
JMIR Research Protocols
Published
2024-10-10
Volume
13
Pages
e58195
ISSN
1929-0748 (ISSN-L)
OpenAlex
W4401788886
Cited by
28
References
32
Citations by year
2026: 19 · 2025: 9
FWCI
11.06
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • JMIR Research Protocols (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • U.S. Department of Defense (W81XWH2210739, W81XWH)
  • Agency for Healthcare Research and Quality (R21 HS028511)
Topics
  • Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
Socratic dialogue, cognitive behavioral therapy, generative AI, large language models, multi-agent systems, digital mental health tools, feasibility, acceptability, usability, user satisfaction, chatbots, access to mental health care, hallucination mitigation
MeSH terms
Artificial Intelligence, Mental Disorders, Feasibility Studies, Humans, Cognitive Behavioral Therapy

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