The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Targeted Radiotherapy with Gold Nanoparticles: Current Status and Future Perspectives
Open accessAbstract
Radiation therapy (RT) is the treatment of cancer and other diseases with ionizing radiation. The ultimate goal of RT is to destroy all the disease cells while sparing healthy tissue. Towards this goal, RT has advanced significantly over the past few decades in part due to new technologies including: multileaf collimator-assisted modulation of radiation beams, improved computer-assisted inverse treatment planning, image guidance, robotics with more precision, better motion management strategies, stereotactic treatments and hypofractionation. With recent advances in nanotechnology, targeted RT with gold nanoparticles (GNPs) is actively being investigated as a means to further increase the RT therapeutic ratio. In this review, we summarize the current status of research and development towards the use of GNPs to enhance RT. We highlight the promising emerging modalities for targeted RT with GNPs and the corresponding preclinical evidence supporting such promise towards potential clinical translation. Future prospects and perspectives are discussed.
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Cites
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Using immunotherapy to boost the abscopal effect
Ngwa, W., Irabor, O. C., Schoenfeld, J. D., Hesser, J., Demaria, S., & Formenti, S. C. (2018) · Nature Reviews Cancer · doi:10.1038/nrc.2018.6 · Cited by 1,260
Self-citationCancer nanomedicine for combination cancer immunotherapy
Nam, J., Son, S., Park, K. S., Zou, W., Shea, L. D., & Moon, J. J. (2019) · Nature Reviews Materials · doi:10.1038/s41578-019-0108-1 · Cited by 940
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Chen, X., Song, J., Chen, X., & Yang, H. (2019) · Chemical Society Reviews · doi:10.1039/c8cs00921j · Cited by 401
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Metadata
- Authors
- Ngwa, W., Kumar, R., Sridhar, S., Korideck, H., Zygmanski, P., Cormack, R. A., Berbeco, R., & Makrigiorgos, G. M.
- Venue
- Nanomedicine
- Publisher
- Informa UK Limited
- Published
- 2014-05
- Volume
- 9
- Issue
- 7
- Pages
- 1063-1082
- ISSN
- 1743-5889 (ISSN-L)
- 1748-6963
- OpenAlex
- W2064090537
- Cited by
- 171
- References
- 7
- FWCI
- 11.87
- Type
- journal article
- Language
- en
- Open access
- green
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- Ngwa, W., Kumar, R., Sridhar, S., Korideck, H., Zygmanski, P., Cormack, R. A., Berbeco, R., & Makrigiorgos, G. M. (2014). Targeted Radiotherapy with Gold Nanoparticles: Current Status and Future Perspectives. Nanomedicine. https://doi.org/10.2217/nnm.14.55
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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