Effect of Bilateral Oophorectomy on Women's Long-Term Health
Open accessAbstract
Bilateral oophorectomy at the time of hysterectomy for benign disease is commonly practiced in order to prevent the subsequent development of ovarian cancer or other ovarian pathology that might require additional surgery. At present, bilateral oophorectomy is performed in 78% of women aged between 45 and 64 years having a hysterectomy, and a total of approximately 300,000 prophylactic oophorectomies are performed in the USA every year. Estrogen deficiency resulting from pre- and post-menopausal oophorectomies has been associated with higher risks of coronary heart disease, stroke, hip fracture, Parkinsonism, dementia, cognitive impairment, depression and anxiety in many studies. While ovarian cancer accounts for 14,800 deaths per year in the USA, coronary heart disease accounts for 350,000 deaths per year. In addition, 100,000 cases of dementia may be attributable annually to prior bilateral oophorectomy. At present, observational studies suggest that bilateral oophorectomy may do more harm than good. In women who are not at high risk of developing ovarian or breast cancer, removing the ovaries at the time of hysterectomy should be approached with caution.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Previous reports in the literature indicate that both ovarian conservation and oophorectomy are linked to increased CVD risk.
“The attenuation of the increased risk of composite CVD after the exclusion of women with hysterectomy supports previous reports in the literature that both ovarian conservation and oophorectomy are linked to increased CVD risk. 33”
From Risk of cardiovascular outcomes among women with endometriosis in the United Kingdom: a retrospective matched cohort study (2021) · cites this paper as [33]
Cites
Jemal, A., Siegel, R. L., Ward, E., Hao, Y., Xu, J., Murray, T., & Thun, M. J. (2008) · CA A Cancer Journal for Clinicians · doi:10.3322/ca.2007.0010 · Cited by 10,184 · see citing works
Shumaker, S. A., Legault, C., Rapp, S. R., Thal, L., Wallace, R. B., Ockene, J. K., Hendrix, S. L., Jones III, B. N., Assaf, A. R., Jackson, R. D., et al. (2003) · JAMA · doi:10.1001/jama.289.20.2651 · Cited by 2,178 · see citing works
Mortality after all major types of osteoporotic fracture in men and women: an observational study
Nguyen, T. V., Schneider, D. L., Sambrook, P. N., & Eisman, J. A. (1999) · The Lancet · doi:10.1016/s0140-6736(98)09075-8 · Cited by 1,926 · see citing works
Estrogen Actions in the Central Nervous System
McEwen, B. S., & Alves, S. E. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.3.0365 · Cited by 1,483 · see citing works
Shumaker, S. A. (2004) · JAMA · doi:10.1001/jama.291.24.2947 · Cited by 1,360 · see citing works
Menopause and the Risk of Coronary Heart Disease in Women
Colditz, G. A., Willett, W. C., Stampfer, M. J., ROSNER, B. A., Speizer, F. E., & Hennekens, C. H. (1987) · New England Journal of Medicine · doi:10.1056/nejm198704303161801 · Cited by 1,153 · see citing works
Androgen Levels in Adult Females: Changes with Age, Menopause, and Oophorectomy
Davison, S. L., Bell, R., Donath, S., Montalto, J. G., & Davis, S. R. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0212 · Cited by 998 · see citing works
Transdermal testosterone treatment in women with impaired sexual function after oophorectomy.
Shifren, J. L., Braunstein, G. D., Simon, J. A., Casson, P. R., Buster, J. E., Redmond, G. P., Burki, R. E., Ginsburg, E. S., Rosen, R. C., Leiblum, S. R., et al. (2000) · New England Journal of Medicine · doi:10.1056/nejm200009073431002 · Cited by 954 · see citing works
Estrogen Therapy in Postmenopausal Women
Yaffe, K. S., Sawaya, G. F., Lieberburg, I. M., & Grady, D. G. (1998) · JAMA · doi:10.1001/jama.279.9.688 · Cited by 941 · see citing works
Effect of Estrogen Plus Progestin on Global Cognitive Function in Postmenopausal Women
Rapp, S. R., Espeland, M. A., Shumaker, S. A., Henderson, V. W., Brunner, R. L., Manson, J. E., Gass, M. L. S., Stefanick, M. L., Lane, D. S., Hays-Grudo, J., et al. (2003) · JAMA · doi:10.1001/jama.289.20.2663 · Cited by 927 · see citing works
Hormone Replacement Therapy and Incidence of Alzheimer Disease in Older Women The Cache County Study
Zandi, P. P. (2002) · JAMA · doi:10.1001/jama.288.17.2123 · Cited by 908 · see citing works
Menopause and Coronary Heart Disease
Gordon, T., Kannel, W. B., Hjortland, M. C., & McNAMARA, P. M. (1978) · Annals of Internal Medicine · doi:10.7326/0003-4819-89-2-157 · Cited by 904 · see citing works
Stampfer, M. J., Colditz, G. A., Willett, W. C., Speizer, F. E., & Hennekens, C. H. (1988) · New England Journal of Medicine · doi:10.1056/nejm198808043190503 · Cited by 892 · see citing works
Mortality and morbidity after hip fractures.
Keene, G. S., Parker, M., & Pryor, G. A. (1993) · BMJ · doi:10.1136/bmj.307.6914.1248 · Cited by 880 · see citing works
Rocca, W. A., Bower, J. H., Maraganore, D. M., Ahlskog, J. E., Grossardt, B. R., de Andrade, M., & Melton, L. J. (2007) · Neurology · doi:10.1212/01.wnl.0000276984.19542.e6 · Cited by 827 · see citing works
Self-citationEspeland, M. A. (2004) · JAMA · doi:10.1001/jama.291.24.2959 · Cited by 794 · see citing works
Atsma, F., Bartelink, M.-L. E. L., Grobbee, D. E., & van der Schouw, Y. T. (2006) · Menopause · doi:10.1097/01.gme.0000218683.97338.ea · Cited by 744 · see citing works
The Nurses' Health Study: 20-Year Contribution to the Understanding of Health Among Women
Colditz, G. A., Manson, J. E., & Hankinson, S. E. (1997) · Journal of Women s Health · doi:10.1089/jwh.1997.6.49 · Cited by 739 · see citing works
Sherwin, B. B. (1988) · Psychoneuroendocrinology · doi:10.1016/0306-4530(88)90060-1 · Cited by 705 · see citing works
Endogenous Hormones and the Risk of Hip and Vertebral Fractures among Older Women
Cummings, S. R., Browner, W. S., Bauer, D. C., Stone, K. L., Ensrud, K. E., Jamal, S. A., & Ettinger, B. B. (1998) · New England Journal of Medicine · doi:10.1056/nejm199809103391104 · Cited by 660 · see citing works
Hormone Replacement Therapy and Cognition
LeBlanc, E. S., Janowsky, J. S., Chan, B. K. S., & Nelson, H. D. (2001) · JAMA · doi:10.1001/jama.285.11.1489 · Cited by 658 · see citing works
Parker, W. H., Broder, M. S., Chang, E., Feskanich, D., Farquhar, C., Liu, Z., Shoupe, D., Berek, J. S., Hankinson, S., & Manson, J. E. (2009) · Obstetrics & Gynecology · doi:10.1097/aog.0b013e3181a11c64 · Cited by 640 · see citing works
Self-citationAge at menopause as a risk factor for cardiovascular mortality
van der Schouw, Y. T., van der Graaf, Y., Steyerberg, E. W., Eijkemans, M. J. C., & Banga, J. D. (1996) · The Lancet · doi:10.1016/s0140-6736(96)90075-6 · Cited by 616 · see citing works
Estrogen reduces neuronal generation of Alzheimer β-amyloid peptides
Xu, H., Gouras, G. K., Greenfield, J. P., Vincent, B., Näslund, J., Mazzarelli, L., Fried, G., Jovanovic, J. N., Seeger, M., Relkin, N. R., et al. (1998) · Nature Medicine · doi:10.1038/nm0498-447 · Cited by 557 · see citing works
Survival patterns after oophorectomy in premenopausal women: a population-based cohort study
Rocca, W. A., Grossardt, B. R., de Andrade, M., Malkasian, G. D., & Melton, L. J. (2006) · The Lancet Oncology · doi:10.1016/s1470-2045(06)70869-5 · Cited by 548 · see citing works
Self-citationJUDD, H. L., JUDD, G. E., LUCAS, W. E., & YEN, S. S. C. (1974) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-39-6-1020 · Cited by 511 · cited 1× · see citing works
“Postmenopausal ovaries continue to produce significant amounts of the androgens testosterone and androstenedione, which are converted to estrogen peripherally [1,2].”
BackgroundBurger, H. G., Dudley, E. C., Cui, J., Dennerstein, L., & Hopper, J. L. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.8.6740 · Cited by 439 · see citing works
Hogervorst, E., Williams, J. M., Budge, M. M., Riedel, W. J., & Jolles, J. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00410-3 · Cited by 438 · see citing works
The role of androgen in the maintenance of sexual functioning in oophorectomized women.
Sherwin, B. B., & Gelfand, M. M. (1987) · Psychosomatic Medicine · doi:10.1097/00006842-198707000-00009 · Cited by 394 · see citing works
Estrogen, Menopause, and the Aging Brain: How Basic Neuroscience Can Inform Hormone Therapy in Women
Morrison, J. H., Brinton, R. D., Schmidt, P. J., & Gore, A. C. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3369-06.2006 · Cited by 388 · see citing works
Laughlin, G. A., Barrett-Connor, E. L., Kritz‐Silverstein, D. C., & von Mühlen, D. G. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.2.6405 · Cited by 381 · see citing works
AN EPIDEMIOLOGIC STUDY OF HIP FRACTURE IN POSTMENOPAUSAL WOMEN
Kreiger, N., Kelsey, J. L., Holford, T. R., & O’Connor, T. (1982) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113388 · Cited by 336 · see citing works
Increased risk of parkinsonism in women who underwent oophorectomy before menopause
Rocca, W. A., Bower, J. H., Maraganore, D. M., Ahlskog, J. E., Grossardt, B. R., de Andrade, M., & Melton, L. J. (2007) · Neurology · doi:10.1212/01.wnl.0000280573.30975.6a · Cited by 308 · see citing works
Self-citationDiagnosis and treatment of atrophic vaginitis.
Bachmann, G. A., & Nevadunsky, N. S. (2000) · PubMed · Cited by 291 · see citing works
Ovarian Androgen Production in Postmenopausal Women
Fogle, R. H., Stanczyk, F. Z., Zhang, X., & Paulson, R. J. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-0581 · Cited by 286 · see citing works
Hormone Therapy and Risk of Alzheimer Disease
Resnick, S. M., & Henderson, V. W. (2002) · JAMA · doi:10.1001/jama.288.17.2170 · Cited by 286 · see citing works
Raisz, L. G., Wiita, B., Artis, A., Bowen, A., Schwartz, S., Trahiotis, M., Shoukri, K., & Smith, J. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.1.8550780 · Cited by 279 · see citing works
Postmenopausal hormone therapy and Alzheimer's disease risk: interaction with age
Henderson, V. W. (2004) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2003.024927 · Cited by 265 · see citing works
Ovarian Conservation at the Time of Hysterectomy for Benign Disease
Parker, W. H., Broder, M. S., Liu, Z., Shoupe, D., Farquhar, C. M., & Berek, J. S. (2005) · Obstetrics and Gynecology · doi:10.1097/01.aog.0000167394.38215.56 · Cited by 263 · see citing works
Self-citationVaginal atrophy in the postmenopausal woman. The importance of sexual activity and hormones
Leiblum, S. R. (1983) · JAMA · doi:10.1001/jama.249.16.2195 · Cited by 263 · see citing works
Howard, B. V., Kuller, L., Langer, R., Manson, J. E., Allen, C., Assaf, A., Cochrane, B. B., Larson, J. C., Lasser, N., Rainford, M., et al. (2005) · Circulation · doi:10.1161/01.cir.0000159344.21672.fd · Cited by 248 · see citing works
Menstrual Factors and Risk of Breast Cancer
Brinton, L. A., Schairer, C., Hoover, R. N., & Fraumeni, J. F. (1988) · Cancer Investigation · doi:10.3109/07357908809080645 · Cited by 247 · see citing works
Løkkegaard, E., Jovanovic, Z., Heitmann, B. L., Keiding, N., Ottesen, B., & Pedersen, A. T. (2006) · Maturitas · doi:10.1016/j.maturitas.2005.04.009 · Cited by 243 · see citing works
(1981) · PubMed · Cited by 235 · see citing works
Caffeine, postmenopausal estrogen, and risk of Parkinson’s disease
Ascherio, A., Chen, H., Schwarzschild, M. A., Zhang, S. M., Colditz, G. A., & Speizer, F. E. (2003) · Neurology · doi:10.1212/01.wnl.0000046523.05125.87 · Cited by 233 · see citing works
Markowska, A. L., & Savonenko, A. V. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-24-10985.2002 · Cited by 230 · see citing works
Gibbs, R. B., & Aggarwal, P. (1998) · Hormones and Behavior · doi:10.1006/hbeh.1998.1451 · Cited by 212 · see citing works
Vaginal Atrophy in the Postmenopausal Woman
Leiblum, S. R. (1983) · JAMA · doi:10.1001/jama.1983.03330400041022 · Cited by 208 · see citing works
Endogenous Estrogen Exposure and Cardiovascular Mortality Risk in Postmenopausal Women
de Kleijn, M. J. J. (2002) · American Journal of Epidemiology · doi:10.1093/aje/155.4.339 · Cited by 201 · see citing works
The Malignant Potential of Small Cystic Ovarian Tumors in Women over 50 Years of Age
Bailey, C. L., Ueland, F. R., Land, G. L., DePriest, P. D., Gallion, H. H., Kryscio, R. J., & van Nagell, J. R. (1998) · Gynecologic Oncology · doi:10.1006/gyno.1998.4965 · Cited by 196 · see citing works
Böös, J. N., von Schoultz, B., & Carlström, K. (1993) · Journal of Psychosomatic Obstetrics & Gynecology · doi:10.3109/01674829309084451 · Cited by 188 · see citing works
Long-term risk of depressive and anxiety symptoms after early bilateral oophorectomy
Rocca, W. A., Grossardt, B. R., Geda, Y. E., Gostout, B. S., Bower, J. H., Maraganore, D. M., de Andrade, M., & Melton, L. J. (2018) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0000000000001229 · Cited by 169 · see citing works
Self-citationArmstrong, K., Schwartz, J. S., Randall, T. C., Rubin, S. C., & Weber, B. (2004) · Journal of Clinical Oncology · doi:10.1200/jco.2004.06.090 · Cited by 161 · see citing works
Risk of Parkinson disease in women
Ragonese, P., D’Amelio, M., Salemi, G., Aridon, P., Gammino, M., Epifanio, A., Morgante, F., & Savettieri, G. (2004) · Neurology · doi:10.1212/wnl.62.11.2010 · Cited by 158 · see citing works
Long-term risk of depressive and anxiety symptoms after early bilateral oophorectomy
Rocca, W. A., Grossardt, B. R., Geda, Y. E., Gostout, B. S., Bower, J. H., Maraganore, D. M., de Andrade, M., & Melton, L. J. (2008) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e318174f155 · Cited by 154 · see citing works
Self-citationMemory Functioning at Menopause: Impact of Age in Ovariectomized Women
Nappi, R. E., Sinforiani, E., Mauri, M. F., Bono, G., Polatti, F., & Nappi, G. (1999) · Gynecologic and Obstetric Investigation · doi:10.1159/000010058 · Cited by 151 · see citing works
Total and Free Estrogens and Androgens in Postmenopausal Women with Hip Fractures*
DAVIDSON, B. J., Ross, R. K., Paganini‐Hill, A., Hammond, G. D., Siiteri, P. K., & Judd, H. L. (1982) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-54-1-115 · Cited by 133 · see citing works
Reproductive Factors and Risk of Myocardial Infarction
Palmer, J. R., Rosenberg, L. A., & Shapiro, S. (1992) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a116513 · Cited by 133 · see citing works
Fracture Risk After Bilateral Oophorectomy in Elderly Women
Melton, L. J., Khosla, S., Malkasian, G. D., Achenbach, S. J., Oberg, A. L., & Riggs, B. L. (2003) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2003.18.5.900 · Cited by 126 · see citing works
Effect of Surgical Menopause on Cognitive Functions
Farrag, A.-K. F., Khedr, E. M., Abdel‐Aleem, H., & Rageh, T. A. (2002) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000048652 · Cited by 124 · see citing works
Paclitaxel-induced apoptosis in MCF-7 breast-cancer cells
Saunders, D. E., Lawrence, W. D., CHRISTENSEN, C. W., Wappler, N. L., Ruan, H., & Deppe, G. (1997) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19970117)70:2 · Cited by 121 · see citing works
Chen, S., Nilsen, J., & Brinton, R. D. (2006) · Endocrinology · doi:10.1210/en.2006-0495 · Cited by 121 · see citing works
Elit, L., Esplen, M. J., Butler, K., & Narod, S. A. (2001) · Familial Cancer · doi:10.1023/a:1021119405814 · Cited by 120 · see citing works
Gonadal Function and the Development of Coronary Heart Disease
Ritterband, A. B., Jaffe, I. A., Densen, P. M., Magagna, J. F., & REED, E. (1963) · Circulation · doi:10.1161/01.cir.27.2.237 · Cited by 105 · see citing works
Ovarian cancer in women with prior hysterectomy: a 14-year experience at the University of Miami.
Sightler, S. E., Boike, G. M., Estape, R. E., & Averette, H. E. (1991) · PubMed · Cited by 104 · see citing works
Advancing the Study of Stroke in Women
Bushnell, C., Hurn, P. D., Colton, C. A., Miller, V. M., del Zoppo, G., Elkind, M. S. V., Stern, B. J., Herrington, D. M., Ford-Lynch, G., Gorelick, P. B., et al. (2006) · Stroke · doi:10.1161/01.str.0000236053.37695.15 · Cited by 102 · see citing works
Shifren, J. L., & Avis, N. E. (2007) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e318032c505 · Cited by 100 · see citing works
Risk of myocardial infarction after oophorectomy and hysterectomy
Falkeborn, M., Schairer, C., Naessén, T., & Persson, I. (2000) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(00)00187-6 · Cited by 96 · see citing works
Mack, W. J., Slater, C. C., Xiang, M., Shoupe, D., Løbo, R. A., & Hodis, H. N. (2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2004.01.034 · Cited by 87 · see citing works
Self-citationHysterectomy, Oophorectomy in Premenopause, and Risk of Breast Cancer
Parazzini, F., Braga, C., Vecchia, C. L., Negri, E., Acerboni, S., & Franceschi, S. (1997) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(97)00295-0 · Cited by 83 · see citing works
Hartge, P. A., Whittemore, A. S., Itnyre, J., McGowan, L., & Cramer, D. W. (1994) · PubMed · Cited by 83 · see citing works
Christ, J. E., & Lotze, E. C. (1975) · PubMed · Cited by 75 · see citing works
Type of menopause, patterns of hormone therapy use, and hot flashes
Gallicchio, L. M., Whiteman, M. K., Tomic, D., Miller, K. P., LANGENBERG, P. W., & Flaws, J. A. (2006) · Fertility and Sterility · doi:10.1016/j.fertnstert.2005.10.033 · Cited by 73 · see citing works
Cardiovascular morbidity in relation to ovarian function after hysterectomy
Luoto, R. M., Kaprio, J. A., Reunanen, A., & Rutanen, E. ‐. (1995) · Obstetrics and Gynecology · doi:10.1016/0029-7844(94)00456-n · Cited by 73 · see citing works
Increased Mortality for Neurological and Mental Diseases following Early Bilateral Oophorectomy
Rivera, C. M., Grossardt, B. R., Rhodes, D. J., & Rocca, W. A. (2009) · Neuroepidemiology · doi:10.1159/000211951 · Cited by 71 · see citing works
Self-citationAndrogen deficiency in the oophorectomized woman
Shifren, J. L. (2002) · Fertility and Sterility · doi:10.1016/s0015-0282(02)02970-9 · Cited by 70 · see citing works
The risk of breast cancer following reproductive surgery
Kreiger, N., Sloan, M., Cotterchio, M., & Kirsh, V. A. (1999) · European Journal of Cancer · doi:10.1016/s0959-8049(98)00343-8 · Cited by 70 · see citing works
Reproductive factors as predictors of bone density and fractures in women at the age of 70
Johansson, C., Mellström, D., & Milsom, I. (1993) · Maturitas · doi:10.1016/0378-5122(93)90122-x · Cited by 64 · see citing works
Oophorectomy in Premenopausal Women
Teplin, V., Vittinghoff, E., Lin, F., Learman, L. A., Richter, H. E., & Kuppermann, M. (2007) · Obstetrics and Gynecology · doi:10.1097/01.aog.0000252700.03133.8b · Cited by 63 · see citing works
HYSTERECTOMY, TUBAL STERILIZATION, AND THE RISK OF BREAST CANCER
Irwin, K. L., LEE, N. C., Peterson, H. B., RUBIN, G. L., Wingo, P. A., Mandel, M. G., & THE CANCER AND STEROID HORMONE STUDY GROUP (1988) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114912 · Cited by 62 · see citing works
The residual ovary syndrome: a 20-year experience
Dekel, A., Efrat, Z., Orvieto, R., Levy, T., Dicker, D., Gal, R., & Ben‐Rafael, Z. (1996) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/0301-2115(96)00250-3 · Cited by 62 · see citing works
Estrogen regulates neprilysin activity in rat brain
Huang, J., Guan, H., Booze, R. M., Eckman, C. B., & Hersh, L. B. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.05.085 · Cited by 60 · see citing works
Hysterectomy, Oophorectomy, and Cognitive Function in Older Women
Kritz‐Silverstein, D. C., & Barrett-Connor, E. L. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50008.x · Cited by 55 · see citing works
Hysterectomy versus hysterectomy plus oophorectomy for premenopausal women
Orozco, L. J., Tristan, M. G., Vreugdenhil, M. M. T., & Salazar, A. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005638.pub3 · Cited by 52 · see citing works
Hodis, H. N., & Mack, W. J. (2002) · The American Journal of Cardiology · doi:10.1016/s0002-9149(02)02407-4 · Cited by 46 · see citing works
Use of Estrogens for the Prevention and Treatment of Alzheimer’s Disease
Monk, D., & Brodaty, H. (2000) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000017206 · Cited by 45 · see citing works
Siegfried, T. (2007) · Nature · doi:10.1038/445359a · Cited by 45 · see citing works
Khatibi, A., Agardh, C. –., Shakir, Y. A., Nerbrand, C., Nyberg, P., Lidfeldt, J., & Samsioe, G. (2007) · Climacteric · doi:10.1080/13697130701377265 · Cited by 43 · see citing works
The Effects of Common Genetic Variants in Oncogenes on Ovarian Cancer Survival
Quaye, L., Gayther, S. A., Ramus, S. J., DiCioccio, R. A., McGuire, V. M., Høgdall, E. V. S., Høgdall, C. K., Blaakr, J., Easton, D. F., Ponder, B. A. J., et al. (2008) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-08-0819 · Cited by 41 · see citing works
Effects of Estrogen Deficiency in Women Castrated When Young
Svanberg, L. (1982) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016348209155324 · Cited by 36 · see citing works
Hsia, J. A., Barad, D. H., Margolis, K. L., Rodabough, R. J., McGovern, P. G., Limacher, M. C., Oberman, A., & Smoller, S. (2003) · The American Journal of Cardiology · doi:10.1016/s0002-9149(03)00621-0 · Cited by 36 · see citing works
Oophorectomy as a risk factor for coronary heart disease
Jacoby, V. L., Grady, D., & Sawaya, G. F. (2009) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2008.08.045 · Cited by 31 · see citing works
Self-citationPostmenopausal Bilateral Oophorectomy Is Not Associated With Increased Fracture Risk in Older Women
Antoniucci, D. M., Sellmeyer, D. E., Cauley, J. A., Ensrud, K. E., Schneider, J. L., Vesco, K. K., Cummings, S. R., & Melton, L. J. (2005) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.041220 · Cited by 31 · see citing works
Hysterectomy and oophorectomy are unrelated to bone loss in older women
Kritz‐Silverstein, D. C., von Mühlen, D. G., & Barrett-Connor, E. L. (2003) · Maturitas · doi:10.1016/s0378-5122(03)00242-1 · Cited by 30 · see citing works
Biological characterization of ovarian cancer: prognostic and therapeutic implications
Legge, F., Ferrandina, G., Salutari, V., & Scambia, G. (2005) · Annals of Oncology · doi:10.1093/annonc/mdi916 · Cited by 30 · see citing works
Bone resorption versus estrogen loss following oophorectomy and menopause
Ohta, H., Makita, K., Komukai, S., & Nozawa, S. (2002) · Maturitas · doi:10.1016/s0378-5122(02)00180-9 · Cited by 29 · see citing works
Aziz, A., Bergquist, C., Brännström, M., Nordholm, L. A., & Silfverstolpe, G. (2005) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/j.0001-6349.2005.00658.x · Cited by 27 · see citing works
Wegienka, G., Havstad, S. L., & Kelsey, J. L. (2006) · Journal of Women s Health · doi:10.1089/jwh.2006.15.369 · Cited by 25 · see citing works
Holub, Z., Jandourek, M., Jabor, A., Kliment, L., & Wágnerová, M. (2000) · PubMed · Cited by 23 · see citing works
Dogma, Skepsis, and the Analytic Method
Olive, D. L. (2005) · Obstetrics and Gynecology · doi:10.1097/01.aog.0000173317.49461.52 · Cited by 22 · see citing works
Hysterectomy versus hysterectomy plus oophorectomy for premenopausal women
Orozco, L. J., Salazar, A., Clarke, J., & Tristan, M. G. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005638.pub2 · Cited by 22 · see citing works
Rozario, D., Brown, I., Fung, M. F. K., & Temple, L. (1997) · The American Journal of Surgery · doi:10.1016/s0002-9610(97)00012-3 · Cited by 20 · see citing works
Acute effects of a surgical menopause on serum concentrations of lipoprotein(a)
Cheung, L.-P., Pang, M. W., Lam, C. W. K., Tomlinson, B., Chung, T. K. H., & Haines, C. J. (1998) · Climacteric · doi:10.3109/13697139809080679 · Cited by 18 · see citing works
Bennett, D. A. (2007) · Neuroepidemiology · doi:10.1159/000109999 · Cited by 17 · see citing works
Hysterectomy--analysis of 2901 personally performed procedures.
Ac, N. (1984) · PubMed · Cited by 17 · see citing works
Carotid pulsatility indices in surgical menopause
Mihmanlı, V., Mihmanlı, İ., Kantarcı, F., Aydın, T., YILMAZ, M. H., & Öĝüt, G. (2002) · Archives of Gynecology and Obstetrics · doi:10.1007/s004040100229 · Cited by 16 · see citing works
Management of surgically hypogonadal patients unable to take sex hormone replacement therapy
Nieman, L. K. (2003) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(03)00011-2 · Cited by 15 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Cardiovascular Risks Associated with Gender and Aging
Rodgers, J. L., Jones, J., Bolleddu, S. I., Vanthenapalli, S., Rodgers, L. E., Shah, K., Karia, K., & Panguluri, S. K. (2019) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd6020019 · Cited by 1,081 · see citing works
Iorga, A., Cunningham, C. M., Moazeni, S., Ruffenach, G., Umar, S., & Eghbali, M. (2017) · Biology of Sex Differences · doi:10.1186/s13293-017-0152-8 · Cited by 914 · see citing works
Sex Hormones and Sex Chromosomes Cause Sex Differences in the Development of Cardiovascular Diseases
Arnold, A. P., Cassis, L. A., Eghbali, M., Reue, K., & Sandberg, K. L. (2017) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.116.307301 · Cited by 339 · see citing works
Kuchenbaecker, K. B., McGuffog, L., Barrowdale, D., Lee, A., Soucy, P., Healey, S., Dennis, J., Lush, M., Robson, M., Spurdle, A., et al. (2017) · Journal of the National Cancer Institute · doi:10.1093/jnci/djw302 · Cited by 294 · see citing works
Endometriosis and cancer: a systematic review and meta-analysis
Kvaskoff, M., Mahamat-Saleh, Y., Farland, L. V., Shigesi, N., Terry, K. L., Harris, H. R., Roman, H., Becker, C. M., As-Sanie, S., Zondervan, K. T., et al. (2021) · Human Reproduction Update · doi:10.1093/humupd/dmaa045 · Cited by 303 · see citing works
Rocca, W. A., Grossardt, B. R., & Shuster, L. T. (2011) · Brain Research · doi:10.1016/j.brainres.2010.10.031 · Cited by 283 · see citing works
Self-citationMinireview: translational animal models of human menopause: challenges and emerging opportunities
Diaz Brinton, R. (2012) · Endocrinology · doi:10.1210/en.2012-1340 · Cited by 272 · see citing works
Sex hormones modulate circulating antioxidant enzymes: Impact of estrogen therapy
Bellanti, F., Matteo, M., Rollo, T., de Rosario, F., Greco, P., Vendemiale, G., & Serviddio, G. (2013) · Redox Biology · doi:10.1016/j.redox.2013.05.003 · Cited by 255 · see citing works
Oophorectomy, estrogen, and dementia: A 2014 update
Rocca, W. A., Grossardt, B. R., & Shuster, L. T. (2014) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2014.01.020 · Cited by 230 · see citing works
Self-citationBilateral Oophorectomy and Breast Cancer Risk inBRCA1andBRCA2Mutation Carriers
Kotsopoulos, J., Huzarski, T., Gronwald, J., Singer, C. F., Møller, P., Lynch, H. T., Armel, S. R., Karlan, B. Y., Foulkes, W. D., Neuhausen, S. L., et al. (2016) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djw177 · Cited by 197 · see citing works
Prophylactic salpingectomy in premenopausal low-risk women for ovarian cancer: Primum non nocere
Morelli, M., Venturella, R., Mocciaro, R., Cello, A. D., Rania, E., Lico, D., D’Alessandro, P., & Zullo, F. (2013) · Gynecologic Oncology · doi:10.1016/j.ygyno.2013.03.023 · Cited by 193 · see citing works
Rahman, A., Jackson, H. C., Hristov, H., Isaacson, R., Saif, N., Shetty, T., Etingin, O. R., Henchcliffe, C., Brinton, R. D., & Mosconi, L. (2019) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2019.00315 · Cited by 190 · see citing works
Premature menopause or early menopause and risk of ischemic stroke
Rocca, W. A., Grossardt, B. R., Miller, V. M., Shuster, L. T., & Brown, R. D. (2012) · Menopause · doi:10.1097/gme.0b013e31822a9937 · Cited by 188 · see citing works
“The studies summarized in Table 1 and Figure 1 suggest that the increased risk of stroke or IS is observed both for women who underwent premature or early natural menopause(18,19,22,23) and for women who underwent bilateral oophorectomy.(15,21,23,24)”
BackgroundMethodSelf-citationManchanda, R., Patel, S., Gordeev, V. S., Antoniou, A. C., Smith, S., Lee, A., Hopper, J. L., MacInnis, R. J., Turnbull, C., Ramus, S. J., et al. (2017) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djx265 · Cited by 180 · see citing works
Stone, R. L., Carey, E. T., Fader, A. N., Fitzgerald, J. J., Hammons, L. M., Nensi, A., Park, A. J., Ricci, S., Rosenfield, R. L., Scheib, S. A., et al. (2020) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2020.08.006 · Cited by 154 · see citing works
Estrogen neuroprotection and the critical period hypothesis
Scott, E. L., Zhang, Q.-G., Wang, R., Vadlamudi, R. K., & Brann, D. W. (2011) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2011.10.001 · Cited by 152 · see citing works
Kim, J., & Münster, P. N. (2024) · Annals of Oncology · doi:10.1016/j.annonc.2024.10.824 · Cited by 121 · see citing works
The post-reproductive Fallopian tube: better removed?
Dietl, J., Wischhusen, J., & Häusler, S. F. (2011) · Human Reproduction · doi:10.1093/humrep/der274 · Cited by 98 · see citing works
The SWAN Song: Study of Women’s Health Across the Nation’s Recurring Themes
Santoro, N., & Sutton-Tyrrell, K. (2011) · Obstetrics and Gynecology Clinics of North America · doi:10.1016/j.ogc.2011.05.001 · Cited by 97 · see citing works
Okoth, K., Wang, J., Zemedikun, D., Thomas, G., Nirantharakumar, K., & Adderley, N. (2021) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.16692 · Cited by 88 · see citing works
Watcharin, S., Sovijit, W., Pu, S., Usuda, K., Inoüe, R., Watanabe, G., Yamaguchi, H., & Nagaoka, K. (2019) · Neuroscience Research · doi:10.1016/j.neures.2019.04.005 · Cited by 89 · see citing works
Sex-Specific Features of Calcific Aortic Valve Disease
Summerhill, V. I., Moschetta, D., Orekhov, A. N., Poggio, P., & Myasoedova, V. A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21165620 · Cited by 84 · see citing works
Manchanda, R., Legood, R., Antoniou, A. C., Gordeev, V. S., & Menon, U. (2016) · Journal of Medical Genetics · doi:10.1136/jmedgenet-2016-103800 · Cited by 79 · see citing works
Modifiers of breast and ovarian cancer risks for BRCA1 and BRCA2 mutation carriers
Milne, R. L., & Antoniou, A. C. (2016) · Endocrine Related Cancer · doi:10.1530/erc-16-0277 · Cited by 79 · see citing works
ASCT2 regulates glutamine uptake and cell growth in endometrial carcinoma
Marshall, A. D., van Geldermalsen, M., Otte, N. J., Lum, T., Vellozzi, M., Thoeng, A., Pang, A., Nagarajah, R., Zhang, B. K., Wang, Q., et al. (2017) · Oncogenesis · doi:10.1038/oncsis.2017.70 · Cited by 79 · see citing works
Ovarian cancer: Pathogenesis and current recommendations for prophylactic surgery
Budiana, I. N. G., Angelina, M., & Pemayun, T. G. A. (2019) · Journal of the Turkish-German Gynecological Association · doi:10.4274/jtgga.galenos.2018.2018.0119 · Cited by 77 · see citing works
Salpingectomy as a Means to Reduce Ovarian Cancer Risk
Daly, M. B., Drescher, C. W., Yates, M. S., Jeter, J., Karlan, B. Y., Alberts, D. S., & Lu, K. H. (2015) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-14-0293 · Cited by 71 · see citing works
Wilson, L. F., Pandeya, N., Byles, J., & Mishra, G. D. (2017) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796016001220 · Cited by 72 · see citing works
What We Know about the Long-Term Risks of Hysterectomy for Benign Indication—A Systematic Review
Madueke-Laveaux, O. S., Elsharoud, A., & Al-Hendy, A. A. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10225335 · Cited by 69 · see citing works
Regulation of the Mouse Medial Prefrontal Cortical Synapses by Endogenous Estradiol
Galvin, C., & Ninan, I. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.56 · Cited by 68 · see citing works
Lee, A., Yang, X., Tyrer, J. P., Gentry‐Maharaj, A., Ryan, A., Mavaddat, N., Cunningham, A. P., Carver, T. J., Archer, S., Leslie, G., et al. (2021) · Journal of Medical Genetics · doi:10.1136/jmedgenet-2021-107904 · Cited by 65 · see citing works
Challenging and Complex Decisions in the Management of the BRCA Mutation Carrier
Stan, D. L., Shuster, L. T., Wick, M. J., Swanson, C. L., Pruthi, S., & Bakkum-Gamez, J. N. (2013) · Journal of Women s Health · doi:10.1089/jwh.2013.4407 · Cited by 58 · see citing works
Sex hormones and stroke: Beyond estrogens
Sohrabji, F., Okoreeh, A. K., & Panta, A. (2018) · Hormones and Behavior · doi:10.1016/j.yhbeh.2018.10.010 · Cited by 59 · see citing works
Osteoporosis: A Long-Term and Late-Effect of Breast Cancer Treatments
Shapiro, C. L. (2020) · Cancers · doi:10.3390/cancers12113094 · Cited by 56 · see citing works
Non-cancer endpoints in BRCA1/2 carriers after risk-reducing salpingo-oophorectomy
Cohen, J. V., Chiel, L. E., Boghossian, L., Jones, M., Stopfer, J. E., Powers, J. M., Rebbeck, T. R., Nathanson, K. L., & Domchek, S. M. (2011) · Familial Cancer · doi:10.1007/s10689-011-9480-8 · Cited by 54 · see citing works
de Kort, B. J., Koch, S. E., Wissing, T. B., Krebber, M. M., Bouten, C. V. C., & Smits, A. I. P. M. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.113960 · Cited by 58 · see citing works
Zeibich, L., Koebele, S. V., Bernaud, V. E., Ilhan, Z., Dirks, B., Northup-Smith, S. N., Neeley, R. E., Maldonado, J., Nirmalkar, K., Files, J. A., et al. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.702628 · Cited by 43 · see citing works
Management of sexual problems in cancer patients and survivors
Varela, V. S., Zhou, E. S., & Bober, S. L. (2013) · Current Problems in Cancer · doi:10.1016/j.currproblcancer.2013.10.009 · Cited by 50 · see citing works
BRCAMutation Carriers: Breast and Ovarian Cancer Screening Guidelines and Imaging Considerations
Elezaby, M. A., Lees, B. F., Maturen, K. E., Barroilhet, L. M., Wisinski, K. B., Schrager, S., Wilke, L. G., & Sadowski, E. A. (2019) · Radiology · doi:10.1148/radiol.2019181814 · Cited by 49 · see citing works
Surgically Induced Menopause—A Practical Review of Literature
Secoşan, C. A., Balint, O., Pirtea, L., Grigoraş, D., Bălulescu, L., & Ilina, R. Ş. (2019) · Medicina · doi:10.3390/medicina55080482 · Cited by 48 · see citing works
Fares, E., Parks, R. J., MacDonald, J. K., Egar, J., & Howlett, S. E. (2011) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2011.09.002 · Cited by 47 · see citing works
Feasibility of prophylactic salpingectomy during vaginal hysterectomy
Antosh, D. D., High, R. A., Brown, H. W., Oliphant, S. S., Abed, H., Philip, N., & Grimes, C. L. (2017) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2017.07.017 · Cited by 45 · see citing works
Cardiovascular risk factors and diseases in women undergoing hysterectomy with ovarian conservation
Laughlin-Tommaso, S. K., Khan, Z., Weaver, A. L., Schleck, C. D., Rocca, W. A., & Stewart, E. A. (2015) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0000000000000506 · Cited by 45 · see citing works
Self-citationRisk-Reducing Breast and Gynecological Surgery for BRCA Mutation Carriers: A Narrative Review
Bertozzi, S., Londero, A. P., Xholli, A., Azioni, G., Vora, R. D., Paudice, M., Bucimazza, I., Cedolini, C., & Cagnacci, A. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12041422 · Cited by 44 · see citing works
Craig, C. D., Monk, B. J., Farley, J. H., & Chase, D. M. (2013) · Supportive Care in Cancer · doi:10.1007/s00520-013-2029-7 · Cited by 39 · see citing works
Laughlin-Tommaso, S. K., Fuchs, E. L., Wellons, M., Lewis, C. E., Calderon‐Margalit, R., Stewart, E. A., & Schreiner, P. J. (2018) · Journal of Women s Health · doi:10.1089/jwh.2018.7122 · Cited by 39 · see citing works
Ovarian Cancer Prevention in High-risk Women
Temkin, S. M., Bergstrom, J., Samimi, G., & Minasian, L. M. (2017) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0000000000000318 · Cited by 39 · see citing works
Therapeutic Approaches for Women Predisposed to Breast Cancer
Nathanson, K. L., & Domchek, S. M. (2010) · Annual Review of Medicine · doi:10.1146/annurev-med-010910-110221 · Cited by 35 · see citing works
Level of Estrogen in Females—The Different Impacts at Different Life Stages
Yu, Z., Jiao, Y., Zhao, Y.-H., & Gu, W. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12121995 · Cited by 34 · see citing works
Zhou, E. S., Nekhlyudov, L., & Bober, S. L. (2015) · PubMed Central · doi:10.3978/j.issn.2223-4683.2014.11.07 · Cited by 30 · see citing works
Choi, H. G., Jung, Y. J., & Lee, S. W. (2019) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2019.02.018 · Cited by 30 · see citing works
Fournier, S., Gulemetova, R., Baldy, C., Joseph, V., & Kinkead, R. (2015) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00418.2014 · Cited by 29 · see citing works
Marder, W., Fisseha, S., Ganser, M. A., & Somers, E. C. (2012) · Clinical Medicine Insights Reproductive Health · doi:10.4137/cmrh.s10415 · Cited by 27 · see citing works
Fertility-sparing treatment in women with endometrial cancer
Won, S., Kim, M. K., & Seong, S. J. (2020) · Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine · doi:10.5653/cerm.2020.03629 · Cited by 26 · see citing works
BRCA1/2 test results impact risk management attitudes, intentions, and uptake
O’Neill, S. C., Valdimarsdottir, H. B., DeMarco, T. A., Peshkin, B. N., Graves, K. D., Brown, K., Hurley, K. E., Isaacs, C. J., Hecker, S., & Schwartz, M. D. (2010) · Breast Cancer Research and Treatment · doi:10.1007/s10549-010-0881-4 · Cited by 26 · see citing works
Menopause, hormone therapy and cognition: maximizing translation from preclinical research
Bimonte‐Nelson, H. A., Bernaud, V. E., & Koebele, S. V. (2021) · Climacteric · doi:10.1080/13697137.2021.1917538 · Cited by 25 · see citing works
Stratégies thérapeutiques des tumeurs ovariennes présumées bénignes
Bourdel, N., & Canis, M. J. (2013) · Journal de gynécologie, obstétrique et biologie de la reproduction. Supplément/Journal de gynécologie obstétrique et biologie de la reproduction · doi:10.1016/j.jgyn.2013.09.035 · Cited by 26 · see citing works
Bone-modifying Agents (BMAs) in Breast Cancer
Shapiro, C. L. (2021) · Clinical Breast Cancer · doi:10.1016/j.clbc.2021.04.009 · Cited by 25 · see citing works
Oophorectomy and rate of dementia: a prospective cohort study
Uldbjerg, C. S., Wilson, L. F., Koch, T., Christensen, J., Dehlendorff, C., Priskorn, L., Abildgaard, J., Simonsen, M. K., Lim, Y.-H., Jørgensen, J. T., et al. (2022) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0000000000001943 · Cited by 24 · see citing works
One size does not fit all: how type of menopause and hormone therapy matters for brain health
Gravelsins, L. L., & Galea, L. A. M. (2025) · The British Journal of Psychiatry · doi:10.1192/bjp.2025.52 · Cited by 22 · see citing works
Taking context to heart: Momentary emotions, menstrual cycle phase, and cardiac autonomic regulation
Simon, S. G., Sloan, R. P., Thayer, J. F., & Jamner, L. D. (2021) · Psychophysiology · doi:10.1111/psyp.13765 · Cited by 23 · see citing works
Ovary Development: Insights From a Three-Dimensional Imaging Revolution
Soygur, B., & Laird, D. J. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.698315 · Cited by 23 · see citing works
Farkas, S., Szabó, A., Török, B., Sólyomvári, C., Fazekas, C. L., Bánrévi, K., Correia, P., Chaves, T., & Zelena, D. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.985424 · Cited by 24 · see citing works
Does routine gynecological surgery contribute to an early menopause?
Fenton, A. J., & Panay, N. (2011) · Climacteric · doi:10.3109/13697137.2012.647623 · Cited by 21 · see citing works
Wang, X., Ma, J., Zhang, S., Li, Z., Hong, Z., Jiang, L., Duan, W., & Liu, J. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.731609 · Cited by 20 · see citing works
Gynecological–endocrinological aspects in women carriers of BRCA1/2 gene mutations
Doren, A., Vecchiola, A., Aguirre, B., & Villaseca, P. (2018) · Climacteric · doi:10.1080/13697137.2018.1514006 · Cited by 21 · see citing works
Liu, X., Xiao, Y., Zhu, Q., Cui, Y., Hao, H., Wang, M., Cowan, P. J., Korthuis, R. J., Li, G., Sun, Q., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22137200 · Cited by 18 · see citing works
Ovarian Cancer and BRCA1/2 Testing: Opportunities to Improve Clinical Care and Disease Prevention
Karakasis, K., Burnier, J. V., Bowering, V. L., Oza, A. M., & Lheureux, S. (2016) · Frontiers in Oncology · doi:10.3389/fonc.2016.00119 · Cited by 17 · see citing works
Archer, S., Fennell, N., Colvin, E., Laquindanum, R., Mills, M. A., Dennis, R., Donoso, F. S., Gold, R., Fan, A. C., Downes, K., et al. (2022) · Cancers · doi:10.3390/cancers14112716 · Cited by 17 · see citing works
Anckaerts, C., van Gastel, J., Leysen, V., Hinz, R., Azmi, A., Simoens, P., Shah, D., Kara, F., Langbeen, A., Bols, P. E. J., et al. (2018) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2018.10.012 · Cited by 17 · see citing works
Lee, A., Yang, X., Tyrer, J. P., Gentry‐Maharaj, A., Ryan, A., Mavaddat, N., Cunningham, A. P., Carver, T. J., Archer, S., Leslie, G., et al. (2020) · medRxiv · doi:10.1101/2020.12.04.20244046 · Cited by 17 · see citing works
Estrogens dynamically regulate neurogenesis in the dentate gyrus of adult female rats
Yagi, S., Mohammad, A., Wen, Y., Burrowes, A. A. B., Blankers, S. A., & Galea, L. A. M. (2024) · Hippocampus · doi:10.1002/hipo.23633 · Cited by 16 · see citing works
Zupi, E., Centini, G., Lazzeri, L., Finco, A., Exacoustós, C., Afors, K., Zullo, F., & Petraglia, F. (2015) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2015.04.004 · Cited by 16 · see citing works
Conduit, C., Milne, R. L., Friedlander, M. L., & Phillips, K. (2021) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-21-0141 · Cited by 16 · see citing works
van Egdom, L. S. E., de Kock, M. A., Apon, I., Mureau, M. A. M., Verhoef, C. K., Hazelzet, J. A., & Koppert, L. B. (2019) · Breast Cancer · doi:10.1007/s12282-019-01033-7 · Cited by 15 · see citing works
Koebele, S. V., Hiroi, R., Plumley, Z. M. T., Melikian, R., Prakapenka, A. V., Patel, S., Carson, C. G., Kirby, D., Mennenga, S. E., Mayer, L. P., et al. (2021) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2021.696838 · Cited by 15 · see citing works
Chung, H., Hayashi, K., Dobson, A. J., Sandin, S., Ideno, Y., Hardy, R., Weiderpass, E., & Mishra, G. D. (2025) · Human Reproduction · doi:10.1093/humrep/deaf068 · Cited by 14 · see citing works
Contributing factors for menopausal symptoms after surgical staging for endometrial cancer
Matsuo, K., Gualtieri, M. R., Cahoon, S. S., Toboni, M. D., Machida, H., Moeini, A., Hasegawa, K., Shoupe, D., & Roman, L. D. (2016) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0000000000000576 · Cited by 14 · see citing works
Self-citationTrends of Opportunistic Salpingectomy
Ding, D., Ci, H., Chu, T., Wei, Y., Chen, P., & Hong, M.-K. (2018) · JSLS Journal of the Society of Laparoscopic & Robotic Surgeons · doi:10.4293/jsls.2018.00004 · Cited by 14 · see citing works
Ovary as a Biomarker of Health and Longevity: Insights from Genetics
Pangas, S. A., & Rajkovic, A. (2017) · Seminars in Reproductive Medicine · doi:10.1055/s-0037-1603571 · Cited by 14 · see citing works
Tawfik, M. K., & Ameen, A. M. (2019) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2018-0571 · Cited by 14 · see citing works
Hypertension in Turner syndrome: a review of proposed mechanisms, management and new directions
Jones, L., Blair, J., Hawcutt, D. B., Lip, G. Y. H., & Shantsila, A. (2023) · Journal of Hypertension · doi:10.1097/hjh.0000000000003321 · Cited by 13 · see citing works
Muhit, A. M. M., Woon, L. S., Nor, N. S. N. M., Sidi, H., Kalok, A. H. M., Kampan, N. C., & Shafiee, M. N. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192315545 · Cited by 13 · see citing works
Bužinskienė, D., Marčiukaitytė, R., Šidlovska, E., & Rudaitis, V. (2023) · Medicina · doi:10.3390/medicina59061097 · Cited by 13 · see citing works
Psychosocial Determinants of Marital Satisfaction Among Gynecologic Cancer Survivors in Malaysia
Hatta, S., Woon, L. S., Nor, N. S. N. M., & Nasir, S. M. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.744922 · Cited by 13 · see citing works
Circulating androgens are associated with mood disturbances in young postmenopausal women
Lambrinoudaki, I. V., Bouziou, G., Armeni, E., Spyropoulou, A., Koundi, K. L., Rizos, D., Augoulea, A., Alexandrou, A. P., Creatsa, M. G., Panoulis, C., et al. (2014) · Climacteric · doi:10.3109/13697137.2014.984674 · Cited by 13 · see citing works
Validation of the BOADICEA model for epithelial tubo-ovarian cancer risk prediction in UK Biobank
Yang, X., Wu, Y., Ficorella, L., Wilcox, N., Dennis, J., Tyrer, J. P., Carver, T. J., Pashayan, N., Tischkowitz, M. D., Pharoah, P. D. P., et al. (2024) · British Journal of Cancer · doi:10.1038/s41416-024-02851-z · Cited by 11 · see citing works
Kauffman, R. P., Young, C., & Castracane, V. D. (2021) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2021.111181 · Cited by 13 · see citing works
Gender Differences in Patients With Stable Chest Pain
Sharma, S. P., Manintveld, O. C., Budde, R. P. J., Hirsch, A., Lenzen, M. J., & Galema, T. W. (2022) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2022.01.054 · Cited by 12 · see citing works
Gümüşsoy, S., Gümüşsoy, M., Hortu, İ., & Ergenoğlu, A. M. (2020) · European Archives of Oto-Rhino-Laryngology · doi:10.1007/s00405-020-06164-8 · Cited by 11 · see citing works
Li, T., Jia, S., Hou, D., Wang, X., Li, D., Liu, Y., Cui, D., Liu, X., Hou, C.-M., Wang, P., et al. (2021) · ASN NEURO · doi:10.1177/17590914211014731 · Cited by 11 · see citing works
Ladd, M. K., Peshkin, B. N., Senter, L. A., Baldinger, S. R., Isaacs, C. J., Segal, H., Philip, S. R., Phillips, C., Shane-Carson, K., Martin, A., et al. (2018) · Translational Behavioral Medicine · doi:10.1093/tbm/iby101 · Cited by 11 · see citing works
A Novel Predictive Multi-Marker Test for the Pre-Surgical Identification of Ovarian Cancer
Stephens, A. N., Hobbs, S. J., Kang, S., Bilandzic, M., Rainczuk, A., Oehler, M. K., Jobling, T. W., Plebanski, M., & Allman, R. (2023) · Cancers · doi:10.3390/cancers15215267 · Cited by 10 · see citing works
Crestol, A., de Lange, A. G., Schindler, L. S., Subramaniapillai, S., Nerland, S., Oppenheimer, H., Westlye, L. T., Andreassen, O. A., Agartz, I., Tamnes, C. K., et al. (2024) · Hormones and Behavior · doi:10.1016/j.yhbeh.2024.105596 · Cited by 9 · see citing works
The Appraisement of Antioxidant and Oxidant Status in Women Undergoing Surgical Menopause
Kaur, A., Negi, P., Sarna, V., Prasad, R., Chavan, B., Malhotra, A., & Kaur, G. (2016) · Indian Journal of Clinical Biochemistry · doi:10.1007/s12291-016-0591-8 · Cited by 10 · see citing works
Ovarian cancer: Pathogenesis and current recommendations for prophylactic surgery
Budiana, I. N. G., Angelina, M., & Pemayun, T. G. A. (2018) · Journal of the Turkish-German Gynecological Association · doi:10.4274/jtgga.2018.0119 · Cited by 9 · see citing works
Kotsopoulos, J., Seca, M., Gronwald, J., Huzarski, T., Møller, P., Kim, R. H., Singer, C. F., Karlan, B. Y., Aeilts, A. M., y Cajal, T. R., et al. (2025) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djaf363 · Cited by 8 · see citing works
Park, J. S., Lee, S., Han, J. W., Kim, T. I., Nam, E. J., & Park, H. S. (2018) · Clinical Breast Cancer · doi:10.1016/j.clbc.2018.02.007 · Cited by 7 · see citing works
Is there any difference in hearing function between surgical and natural menopause?
Özgedik, D., Kırbaç, A., & Belgi̇n, E. (2022) · Women & Health · doi:10.1080/03630242.2022.2029801 · Cited by 7 · see citing works
- Authors
- Parker, W. H., Jacoby, V., Shoupe, D., & Rocca, W.
- Affiliations
- University of California, Los Angeles (US)
- University of California, San Francisco (US)
- University of Southern California (US)
- Mayo Clinic (US)
- Corresponding author
- Parker, William H
- Jacoby, Vanessa
- Shoupe, Donna
- Rocca, Walter
- Venue
- Women's Health
- Publisher
- SAGE Publications
- Published
- 2009-09
- Volume
- 5
- Issue
- 5
- Pages
- 565-576
- ISSN
- 1745-5057 (ISSN-L)
- 1745-5065
- OpenAlex
- W2170988125
- Cited by
- 161
- References
- 107
- Citations by year
- 2026: 5 · 2025: 10 · 2024: 11 · 2023: 11 · 2022: 15 · 2021: 18 · 2020: 11 · 2019: 14 · 2018: 9 · 2017: 10 · 2016: 8 · 2015: 9 · 2014: 4 · 2013: 9 · 2012: 5
- FWCI
- 0.74
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Women s Health (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Estrogen and related hormone effects
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Keywords
- bilateral oophorectomy, hysterectomy, prophylactic oophorectomy, estrogen deficiency, menopause, coronary artery disease, stroke, hip fracture, dementia, cognitive impairment, depression, anxiety, parkinsonism, ovarian cancer prevention, long-term health effects
- MeSH terms
- Affect, Decision Making, Female, Health Status, Hip Fractures, Humans, Hysterectomy, Middle Aged, Osteoporosis, Ovariectomy, Ovary, Quality of Life, Time Factors, Women's Health, Treatment Outcome, Risk Assessment, Sexuality
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
