Comorbidity and its impact on disability
Abstract
Older people often suffer from comorbidity, or several chronic conditions simultaneously. Disability rises rapidly as the number of chronic conditions grows, although very ill people who acquire another condition experience attenuated increases. High prevalence conditions such as arthritis tend to have a low or occasionally moderate impact for community residents, while low prevalence ones such as osteoporosis have a high impact; paired conditions sometimes give extra propulsion to disability, as when cerebrovascular disease and hip fracture co-occur. Further research is needed to pin-point combinations of conditions posing great risks and to identify demographic segments in which comorbidity has elevated effects.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Prior studies have shown comorbidities increase disability risk.
“prior studies have already shown that co-morbidities increase the risk of disability.(1, 24, 25)”
From Urinary incontinence and disability in community-dwelling women: A cross-sectional study: Urinary Incontinence and Disability in Ambulatory Women (2015) · cites this paper as [25]
Cites
Statistical Methods for Rates and Proportions
Fleiss, J. L., Levin, B., & Paik, M. C. (2003) · Wiley Series in Probability and Statistics · doi:10.1002/0471445428 · Cited by 18,646 · see citing works
The pre-therapeutic classification of co-morbidity in chronic disease
Feinstein, A. R. (1970) · Journal of Chronic Diseases · doi:10.1016/0021-9681(70)90054-8 · Cited by 1,544 · see citing works
International Classification of Impairments, Disabilities and Handicaps
Ford, B. (1984) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1984.tb103888.x · Cited by 1,284 · see citing works
The importance of classifying initial co-morbidity in evaluating the outcome of diabetes mellitus
Kaplan, M. H., & Feinstein, A. R. (1974) · Journal of Chronic Diseases · doi:10.1016/0021-9681(74)90017-4 · Cited by 668 · see citing works
ANALYTICAL POTENTIAL FOR MULTIPLE CAUSE-OF-DEATH DATA
Israel, R. A., ROSENBERG, H. M., & Curtin, L. R. (1986) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114375 · Cited by 278 · see citing works
The Supplement on Aging to the 1984 National Health Interview Survey.
Fitti, J. E., & Kovar, M. G. (1987) · PubMed · Cited by 254 · see citing works
Rowe, J. W. (1985) · New England Journal of Medicine · doi:10.1056/nejm198503283121305 · Cited by 211 · see citing works
Recent Trends in Mortality Analysis.
B., J., Mantón, K. G., & Stallard, E. (1985) · Population and Development Review · doi:10.2307/1973501 · Cited by 172 · see citing works
From sneezes to adieux: Stages of health for American men and women
Verbrugge, L. M. (1986) · Social Science & Medicine · doi:10.1016/0277-9536(86)90187-5 · Cited by 98 · see citing works
Self-citationMULTIPLE DISORDERS IN THE ELDERLY
Wilson, L. A., Lawson, I. R., & Brass, W. (1962) · The Lancet · doi:10.1016/s0140-6736(62)90627-x · Cited by 78 · see citing works
(1983) · Journal of Gerontology · doi:10.1093/geronj/38.1.122a · Cited by 61 · see citing works
The Health Consequences of Multiple Morbidity in the Elderly
Seeman, T. E., Guralnik, J. M., Kaplan, G. A., Knudsen, L., & Cohen, R. D. (1989) · Journal of Aging and Health · doi:10.1177/089826438900100104 · Cited by 54 · see citing works
Health and Disease among the Oldest Old: A Clinical Perspective
Minaker, K. L., & Rowe, J. W. (1985) · The Milbank Memorial Fund Quarterly Health and Society · doi:10.2307/3349883 · Cited by 43 · see citing works
MULTIPLE PATHOLOGY IN NONAGENARIANS.
Th, H. (1963) · PubMed · Cited by 38 · see citing works
Chappell, N. L. (1981) · Journal of Health and Social Behavior · doi:10.2307/2136371 · Cited by 35 · see citing works
The effect of comorbidity on appropriateness ratings for two gastrointestinal procedures
Kahn, K. L. (1988) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(88)90085-6 · Cited by 22 · see citing works
The Relationship Between Age and the Number of Symptoms Reported by Patients
Denney, D., Kole, D. M., & Matarazzo, R. G. (1965) · Journal of Gerontology · doi:10.1093/geronj/20.1.50 · Cited by 9 · see citing works
Spicer, C. C. (1967) · Springer eBooks · doi:10.1007/978-1-4899-6365-9_5 · Cited by 7 · see citing works
Mantón, K. G. (1985) · PubMed · Cited by 3 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Fried, L. P., Ferrucci, L., Darer, J., Williamson, J. D., & Anderson, G. (2004) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/59.3.m255 · Cited by 4,032 · see citing works
How to measure comorbiditya critical review of available methods
DEGROOT, V, BECKERMAN, H., LANKHORST, G., & BOUTER, L. (2003) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(02)00585-1 · Cited by 1,757 · see citing works
Causes and consequences of comorbidity
Gijsen, R., Hoeymans, N., Schellevis, F. G., Ruwaard, D., Satariano, W. A., & van den Bos, G. A. M. (2001) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(00)00363-2 · Cited by 962 · see citing works
Comorbidity or multimorbidity: what's in a name? A review of literature
van den Akker, M., Buntinx, F., & Knottnerus, J. A. (1996) · European Journal of General Practice · doi:10.3109/13814789609162146 · Cited by 857 · see citing works
Diederichs, C., Berger, K., & Bartels, D. B. (2011) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glq208 · Cited by 693 · see citing works
Seven chronic conditions: their impact on US adults' activity levels and use of medical services
Verbrugge, L. M., & Patrick, D. L. (1995) · American Journal of Public Health · doi:10.2105/ajph.85.2.173 · Cited by 356 · see citing works
Self-citationDisability trends among elderly persons and implications for the future
Waidmann, T. A., & Liu, K. (2000) · The Journals of Gerontology Series B: Psychological Sciences and Social Sciences · doi:10.1093/geronb/55.5.s298 · Cited by 212 · see citing works
Gadermann, A. M., Alonso, J., Vilagut, G., Zaslavsky, A. M., & Kessler, R. C. (2012) · Depression and Anxiety · doi:10.1002/da.21924 · Cited by 210 · see citing works
The influence of co-morbidity on health-related quality of life in asthma and COPD patients
WIJNHOVEN, H. A. H., KRIEGSMAN, D. M. W., HESSELINK, A. E., DE HAAN, M., & SCHELLEVIS, F. G. (2003) · Respiratory Medicine · doi:10.1053/rmed.2002.1463 · Cited by 118 · see citing works
Co-morbidity in rheumatoid arthritis
Mikuls, T. R. (2003) · Best Practice & Research Clinical Rheumatology · doi:10.1016/s1521-6942(03)00041-x · Cited by 122 · see citing works
Alonso, J., Vilagut, G., Chatterji, S., Heeringa, S., Schoenbaum, M., Bedirhan Üstün, T., Rojas-Farreras, S., Angermeyer, M., Bromet, E., Bruffaerts, R., et al. (2011) · Psychological Medicine · doi:10.1017/s0033291710001212 · Cited by 61 · see citing works
Greer, J. A., Xu, R., Propert, K. J., & Arya, L. A. (2015) · Neurourology and Urodynamics · doi:10.1002/nau.22615 · Cited by 24 · see citing works
“We did notmeasure the individual effect of specific co-morbid disease processes on disability, however, the focus of this study was the relationship of urinary incontinence with disabilities with co-morbidities as a possible confounding factor; furthermore, prior studies have already shown that comorbidities increase…”
Result
- Authors
- Verbrugge, L. M., Lepkowski, J. M., & Imanaka, Y.
- Affiliations
- University of Michigan (US)
- ORCID
- Imanaka, Yuichi
- Venue
- The Milbank Quarterly
- Publisher
- JSTOR
- Published
- 1989
- Volume
- 67
- Issue
- 3/4
- Pages
- 450
- ISSN
- 0887-378X (ISSN-L)
- OpenAlex
- W2064876139
- Cited by
- 427
- References
- 19
- Citations by year
- 2026: 4 · 2025: 3 · 2024: 4 · 2023: 5 · 2022: 5 · 2021: 5 · 2020: 9 · 2019: 10 · 2018: 7 · 2017: 9 · 2016: 13 · 2015: 10 · 2014: 14 · 2013: 18 · 2012: 18
- FWCI
- 6.67
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Milbank Quarterly (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (1r01ag006616-01a1)
- National Institute on Aging (R01 AG0-6616)
- Topics
- Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Keywords
- comorbidities, disability, older adults, chronic disease, arthritis, osteoporosis, cerebrovascular disease, hip fracture, disease combinations, disability risk
- MeSH terms
- Activities of Daily Living, Aged, Chronic Disease, Ethnicity, Female, Persons with Disabilities, Humans, Male, Middle Aged, Sex Factors, United States, Comorbidity, Prevalence
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
