Cited by 336Toxic Organic Pollutants ImpactEnvironmental Toxicology and EcotoxicologyEffects and risks of endocrine disrupting chemicals

The DOI matches its Crossref record; 160 of the 175 references it cites were found in a registry or an index.

Stepping Backward to Improve Assessment of PCB Congener Toxicities

Open access

Hansen, Larry G.·1998·Environmental Health Perspectives

DOI 10.2307/3433919

Open this paper in CoChat — free account Open PDF

Abstract

Polychlorinated biphenyls (PCBs) are ubiquitous global contaminants that have been intensively investigated for three decades.They are broad-acting toxicants occurring in complex mixtures and accurate risk assessment has proven to be elusive.Focusing on a limited set of end points and emphasizing a fixed set of congeners have led to more streamlined data sets that are meant to expedite hazard characterization and risk assessment for the most potent congeners-aryl hydrocarbon receptor (AhR) agonists.Unfortunately, this has made it impossible to confirm or deny significant contributions from the more prevalent components of the mixtures.PCBs may be only coincidentally present, rather than causal, in some diseases.Still, attempts to determine associations with incomplete residue data may lead to erroneous conclusions and make accurate risk assessment even more elusive.Responses not mediated through the AhR are presented and emphasize large data gaps.Dissimilar analytical reports emphasize that selection of analytes is not consistent.Collectively, these data confirm that AhR-focused objectives unintentionally created the impression that nonplanar PCBs have little if any potential for hazards to humans and wildlife.Near steady-state exposure of healthy adults are probably of minor consequence except for emerging correlations with non-Hodgkin's lymphoma; however, pulses of exposure to more labile mixtures may contribute to developmental effects without leaving a residue record.More broadly based criteria are suggested and harmonization of data collection and presentation are desirable.A more comprehensive list of PCB congeners is proposed that would provide more adequate data upon which to base associations with adverse outcomes.-

Integrity signals

Registry

Crossref · 10.2307/3433919

Cites

160 of 160 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β
Kuiper, G. G. J. M., Carlsson, B., Grandien, K., Enmark, E., Häggblad, J., Nilsson, S., & Gustafsson, J.-A. (1997) · Endocrinology · doi:10.1210/endo.138.3.4979 · Cited by 4,442
The Merck index
Budavari, S. (1998) · Royal Society of Chemistry eBooks · Cited by 2,741
2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity
Poland, A., & Knutson, J. C. (1982) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pa.22.040182.002505 · Cited by 2,515
Illustrated handbook of physical-chemical properties and environmental fate for organic chemicals
Mackay, D., Shiu, W. Y., & Ching, K. (1992) · Lewis Publishers eBooks · Cited by 1,786
Polychlorinated Biphenyls (PCBs): Environmental Impact, Biochemical and Toxic Responses, and Implications for Risk Assessment
Safe, S. H. (1994) · Critical Reviews in Toxicology · doi:10.3109/10408449409049308 · Cited by 1,760
The E-SCREEN assay as a tool to identify estrogens: an update on estrogenic environmental pollutants.
Soto, A. M., Sonnenschein, C., Chung, K. L., Fernández, M. F., Olea, N., & Serrano, F. (1995) · Environmental Health Perspectives · doi:10.1289/ehp.95103s7113 · Cited by 1,743
Analysis of polychlorinated biphenyls (PCB) by glass capillary gas chromatography
Ballschmiter, K., & Zell, M. (1980) · Fresenius Zeitschrift für Analytische Chemie · doi:10.1007/bf00469758 · Cited by 1,441
Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450
Burke, M. D., Thompson, S., Elcombe, C. R., Halpert, J. R., Haaparanta, T., & Mayer, R. T. (1985) · Biochemical Pharmacology · doi:10.1016/0006-2952(85)90355-7 · Cited by 1,275
Blood Levels of Organochlorine Residues and Risk of Breast Cancer
Wolff, M. S., Toniolo, P. G., Lee, E. W., Rivera, M., & Dubin, N. (1993) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/85.8.648 · Cited by 836
Analytical Chemistry of Pcbs
Erickson, M. D. (1986) · Medical Entomology and Zoology · Cited by 810
Relative Binding Affinity-Serum Modified Access (RBA-SMA) Assay Predicts the Relative In Vivo Bioactivity of the Xenoestrogens Bisphenol A and Octylphenol
Nagel, S. C., Saal, F. S. V., Thayer, K. A., Dhar, M., Boechler, M., & Welshons, W. V. (1997) · Environmental Health Perspectives · doi:10.1289/ehp.9710570 · Cited by 793
Toxic equivalency factors for dioxin-like PCBs
Ahlborg, U. G., Becking, G. C., Birnbaum, L., Brouwer, A., Derks, H., Feeley, M., Golor, G., Hanberg, A., Larsen, J. C., Liem, A. K. D., et al. (1994) · Chemosphere · doi:10.1016/0045-6535(94)90324-7 · Cited by 721
Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses
Saal, F. S. V., Timms, B. G., Montano, M. M., Palanza, P., Thayer, K. A., Nagel, S. C., Dhar, M. D., Ganjam, V. K., Parmigiani, S., & Welshons, W. V. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.5.2056 · Cited by 701
Environmental occurrence, abundance, and potential toxicity of polychlorinated biphenyl congeners: considerations for a congener-specific analysis.
McFarland, V., & Clarke, J. U. (1989) · Environmental Health Perspectives · doi:10.1289/ehp.8981225 · Cited by 700
Complete PCB congener distributions for 17 aroclor mixtures determined by 3 HRGC systems optimized for comprehensive, quantitative, congener‐specific analysis
Frame, G. M., Cochran, J. W., & Bøwadt, S. (1996) · Journal of High Resolution Chromatography · doi:10.1002/jhrc.1240191202 · Cited by 556
Tripartite steroid hormone receptor pharmacology: interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones.
Katzenellenbogen, J., O'Malley, B., & Katzenellenbogen, B. (1996) · Molecular Endocrinology · doi:10.1210/mend.10.2.8825552 · Cited by 537
Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens
McDonnell, D. P., Clemm, D. L., Hermann, T. W., Goldman, M. E., & Pike, J. (1995) · Molecular Endocrinology · doi:10.1210/mend.9.6.8592512 · Cited by 526
The Environmental Estrogen Bisphenol A Stimulates Prolactin Release in Vitro and in Vivo
Steinmetz, R. W., Brown, N. G., Allen, D. L., Bigsby, R. M., & Ben‐Jonathan, N. (1997) · Endocrinology · doi:10.1210/endo.138.5.5132 · Cited by 520
Breast Cancer and Serum Organochlorines: a Prospective Study Among White, Black, and Asian Women
Krieger, N., Wolff, M. S., Hiatt, R. A., Rivera, M., Vogelman∥, J. H., & Orentreich∥, N. (1994) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/86.8.589 · Cited by 489
Estrogen receptor-binding activity of polychlorinated hydroxybiphenyls: conformationally restricted structural probes.
Korach, K. S., Sarver, P. J., Chae, K., McLachlan, J. A., & McKinney, J. D. (1988) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)13092-7 · Cited by 425
Microcontaminants and reproductive impairment of the Forster's tern on Green Bay, Lake Michigan-1983
Kubiak, T. J., Harris, H. J., Smith, L. M., Schwartz, T. R., Stalling, D. L., Trick, J., Sileo, L., Docherty, D. E., & Erdman, T. C. (1989) · Archives of Environmental Contamination and Toxicology · doi:10.1007/bf01225009 · Cited by 406
The E-SCREEN Assay as a Tool to Identify Estrogens: An Update on Estrogenic Environmental Pollutants
Soto, A. M., Sonnenschein, C., Chung, K. L., Fernández, M. F., Olea, N., & Serrano, F. O. (1995) · Environmental Health Perspectives · doi:10.2307/3432519 · Cited by 401
The Ah receptor: Mediator of the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds☆
Okey, A. B., Riddick, D. S., & HARPER, P. (1994) · Toxicology Letters · doi:10.1016/0378-4274(94)90139-2 · Cited by 380
Cytochrome P-450 monooxygenase systems in aquatic species: carcinogen metabolism and biomarkers for carcinogen and pollutant exposure.
Stegeman, J. J., & Lech, J. J. (1991) · Environmental Health Perspectives · doi:10.1289/ehp.90-1519513 · Cited by 371
Estrogenic activity of DDT analogs and polychlorinated biphenyls
Bitman, J., & Cecil, H. C. (1970) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf60172a019 · Cited by 352
PCBs: Structure-Function Relationships and Mechanism of Action
Safe, S. H., Bandiera, S. M., Sawyer, T. W., Robertson, L. W., Safe, L. M., Parkinson, A., Thomas, P. E., Ryan, D. E., Reik, L. M., Levin, W., et al. (1985) · Environmental Health Perspectives · doi:10.2307/3429944 · Cited by 326
Polychlorinated biphenyls as hormonally active structural analogues.
McKinney, J. D., & Waller, C. L. (1994) · Environmental Health Perspectives · doi:10.1289/ehp.94102290 · Cited by 309
Selective retention of hydroxylated PCB metabolites in blood.
Bergman, Å., Klasson‐Wehler, E., & Kuroki, H. (1994) · Environmental Health Perspectives · doi:10.1289/ehp.94102464 · Cited by 304
2,3,7,8‐Tetrachlorodibenzo‐p‐dioxin (TCDD) and Related Compounds as Antioestrogens: Characterization and Mechanism of Action
Safe, S. H., Astroff, B., Harris, M. A., Zacharewski, T. R., Dickerson, R. L., Romkes, M., & Biegel, L. B. (1991) · Pharmacology & Toxicology · doi:10.1111/j.1600-0773.1991.tb01321.x · Cited by 287
High Organochlorine Body Burden in Women With Estrogen Receptor-Positive Breast Cancer
Dewailly, É., Dodin, S., Verreault, R., Ayotte, P., Sauve, L., Morin, J., & Brisson, J. (1994) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/86.3.232 · Cited by 284
Bioaccumulation patterns of hydrocarbons and polychlorinated biphenyls in bivalves, crustaceans, and fishes
Porte, C., & Albaig�s, J. (1994) · Archives of Environmental Contamination and Toxicology · doi:10.1007/bf00203552 · Cited by 269
Estrogenic and antiestrogenic actions of PCBs in the female rat: In vitro and in vivo studies
Jansen, H. T., Cooke, P. S., Porcelli, J., Liu, T., & Hansen, L. G. (1993) · Reproductive Toxicology · doi:10.1016/0890-6238(93)90230-5 · Cited by 267
Self-citation
Neurotoxicity of polychlorinated biphenyls: Structure-activity relationship of individual congeners
Shain, W. G., Bush, B., & Seegal, R. F. (1991) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(91)90131-w · Cited by 246
Alterations in Rat Brain Thyroid Hormone Status Following Pre- and Postnatal Exposure to Polychlorinated Biphenyls (Aroclor 1254)
Morse, D. C., Klasson‐Wehler, E., Wesseling, W., Koeman, J. H., & Brouwer, A. (1996) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1996.0034 · Cited by 242
Proposed PCB congener groupings for epidemiological studies.
Wolff, M. S., Camann, D., Gammon, M. D., & Stellman, S. D. (1997) · Environmental Health Perspectives · doi:10.1289/ehp.9710513 · Cited by 227
Effects of perinatal exposure to specific PCB congeners on thyroid hormone concentrations and thyroid histology in the rat
NESS, D. K., Schantz, S. L., Moshtaghian, J., & Hansen, L. G. (1993) · Toxicology Letters · doi:10.1016/0378-4274(93)90023-q · Cited by 201
Self-citation
Polychlorinated biphenyls: congener-specific analysis of a commercial mixture and a human milk extract
Safe, S. H., Safe, L. M., & Mullin, M. D. (1985) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00061a007 · Cited by 197
A nested case-control study of non-Hodgkin lymphoma and serum organochlorine residues
Rothman, N., Cantor, K. P., Blair, A. E., Bush, D. E., Brock, J. W., Helzlsouer, K. J., Zahm, S. H., Needham, L. L., Pearson, G. R., Hoover, R. N., et al. (1997) · The Lancet · doi:10.1016/s0140-6736(97)02088-6 · Cited by 195
Comprehensive, quantitative, congener-specific analyses of eight aroclors and complete PCB congener assignments on DB-1 capillary GC columns
Frame, G. M., Wagner, R. E., CARNAHAN, J. C. J., Brown, J. F., May, R. J., Smullen, L. A., & Bedard, D. L. (1996) · Chemosphere · doi:10.1016/0045-6535(96)00214-7 · Cited by 187
Estrogen Receptor Expression in Developing Epididymis, Efferent Ductules, and Other Male Reproductive Organs*
Cooke, P. S., Young, P., Hess, R. A., & Cunha, G. R. (1991) · Endocrinology · doi:10.1210/endo-128-6-2874 · Cited by 186
Occurrence and bioaccumulation of organochlorine compounds in fishes from Siskiwit Lake, Isle Royale, Lake Superior
Swackhamer, D. L., & Hites, R. A. (1988) · Environmental Science & Technology · doi:10.1021/es00170a010 · Cited by 179
Polychlorobiphenyls (PCBs), polychlorodibenzo-p-dioxins (PCDDs) and polychlorodibenzofurans (PCDFs) in human milk, blood and adipose tissue
Jensen, A. A. (1987) · The Science of The Total Environment · doi:10.1016/0048-9697(87)90250-6 · Cited by 160
Antiestrogenic Activity of Hydroxylated Polychlorinated Biphenyl Congeners Identified in Human Serum
Moore, M., Mustain, M., Daniel, K. D., Chen, I., Safe, S. H., Zacharewski, T. R., Gillesby, B. E., Joyeu×, A., & Balaguer, P. (1997) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1996.8022 · Cited by 160
Hypothyroidism and Abnormalities in the Kinetics of Thyroid Hormone Metabolism in Rats Treated Chronically with Polychlorinated Biphenyl and Polybrominated Biphenyl*
Byrne, J. J., Carbone, J. P., & HANSON, E. A. (1987) · Endocrinology · doi:10.1210/endo-121-2-520 · Cited by 158
Effects of dichlorodiphenyltrichloroethane (DDT) analogs and polychlorinated biphenyl (PCB) mixtures on 17β-[3H]estradiol binding to rat uterine receptor
Nelson, J. A. (1974) · Biochemical Pharmacology · doi:10.1016/0006-2952(74)90436-5 · Cited by 156
Different competition of thyroxine binding to transthyretin and thyroxine-binding globulin by hydroxy-PCBs, PCDDs and PCDFs
Lans, M. C., Spiertz, C., Brouwer, A., & Koeman, J. H. (1994) · European Journal of Pharmacology Environmental Toxicology and Pharmacology · doi:10.1016/0926-6917(94)90054-x · Cited by 149
3,4,3',4'-Tetrachlorobiphenyl acts as an estrogen in vitro and in vivo
Nesaretnam, K., Corcoran, D., Dils, R., & Darbre, P. D. (1996) · Molecular Endocrinology · doi:10.1210/mend.10.8.8843409 · Cited by 139
Determinants of polychlorinated biphenyls (PCBs), polybrominated biphenyls (PBBs), and dichlorodiphenyl trichloroethane (DDT) levels in the sera of young children.
Jacobson, J. L., Humphrey, H. E. B., Jacobson, S. W., Schantz, S. L., Mullin, M. D., & Welch, R. (1989) · American Journal of Public Health · doi:10.2105/ajph.79.10.1401 · Cited by 136
Quantitative characterization of polychlorinated biphenyl mixtures (aroclors® 1248, 1254 and 1260) by gas chromatograpy using capillary columns
Albro, P. W., Corbett, J. T., & Schroeder, J. L. (1981) · Journal of Chromatography A · doi:10.1016/s0021-9673(00)81818-x · Cited by 135
On the substrate specificity of cytochrome P450IIIA1.
Namkung, M. J., Yang, H. L., Hulla, J. E., & Juchau, M. R. (1988) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)09889-x · Cited by 134
Effects of a Polychlorinated Biphenyl Mixture (Aroclor 1254) and DDT on Biliary Thyroxine Excretion in Rats1
Bastomsky, C. H. (1974) · Endocrinology · doi:10.1210/endo-95-4-1150 · Cited by 133
Determination of PCB Metabolic, Excretion, and Accumulation Rates for Use as Indicators of Biological Response and Relative Risk
Brown, J. F. (1994) · Environmental Science & Technology · doi:10.1021/es00062a013 · Cited by 133
Characterization of the Polychlorinated Biphenyls in the Sediments of Woods Pond: Evidence for Microbial Dechlorination of Aroclor 1260 in Situ
Bedard, D. L., & May, R. J. (1995) · Environmental Science & Technology · doi:10.1021/es950262e · Cited by 133
Uterotrophic activity of polychlorinated biphenyls (PCB) and induction of precocious reproductive aging in neonatally treated female rats
Gellert, R. J. (1978) · Environmental Research · doi:10.1016/0013-9351(78)90149-4 · Cited by 129
Regulation of cytochrome P-450p by phenobarbital and phenobarbital-like inducers in adult rat hepatocytes in primary monolayer culture and in vivo
Schuetz, E. G., Wrighton, S. A., Safe, S. H., & Guzelian, P. S. (1986) · Biochemistry · doi:10.1021/bi00353a027 · Cited by 129
Disposition of polychlorinated biphenyl congeners in occupationally exposed persons*1
WOLFF, M. (1982) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(82)90128-4 · Cited by 124
Monooxygenase Induction and Chlorobiphenyls in the Deep-Sea Fish Coryphaenoides armatus
Stegeman, J. J., Kloepper-Sams, P. J., & Farrington, J. W. (1986) · Science · doi:10.1126/science.231.4743.1287 · Cited by 120
PCB and dioxin levels in plasma and human milk of 418 dutch women and their infants. Predictive value of PCB congener levels in maternal plasma for fetal and infant's exposure to PCBs and dioxins
Koopman-Esseboom, C., Huisman, M., Weisglas‐Kuperus, N., van der Paauw, C. G., Tuinstra, L. G. M. T., Boersma, E. R., & Sauer, P. J. J. (1994) · Chemosphere · doi:10.1016/0045-6535(94)90428-6 · Cited by 119
Distribution of polychlorinated biphenyl congeners and other halocarbons in whole fish and muscle among Lake Ontario salmonids
Niimi, A. J., & Oliver, B. G. (1989) · Environmental Science & Technology · doi:10.1021/es00178a010 · Cited by 118
Over-water and over-land polychlorinated biphenyls in Green Bay, Lake Michigan
Hornbuckle, K. C., Achman, D. R., & Eisenreich, S. J. (1993) · Environmental Science & Technology · doi:10.1021/es00038a008 · Cited by 118
Dietary Exposure of Mink to Carp from Saginaw Bay. 3. Characterization of Dietary Exposure to Planar Halogenated Hydrocarbons, Dioxin Equivalents, and Biomagnification
Tillitt, D. E., Gale, R. W., Meadows, J. C., Zajicek, J. L., Peterman, P. H., Heaton, S. N., Jones, P. D., Bursian, S. J., Kubiak, T. J., Giesy, J. P., et al. (1995) · Environmental Science & Technology · doi:10.1021/es9503140 · Cited by 118
Ortho-substituted polychlorinated biphenyls alter calcium regulation by a ryanodine receptor-mediated mechanism: structural specificity toward skeletal- and cardiac-type microsomal calcium release channels.
WONG, P. W. K., & Pessah, I. N. (1996) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)08790-5 · Cited by 116
Human milk as a bioindicator for body burden of PCDDs, PCDFs, organochlorine pesticides, and PCBs.
Fürst, P., Fürst, C., & Wilmers, K. (1994) · Environmental Health Perspectives · doi:10.1289/ehp.102-1566908 · Cited by 114
Exposure of remote maritime populations to coplanar PCBs.
Dewailly, É., Ryan, J., Laliberté, C., Bruneau, S., Weber, J. P., Gingras, S., & Carrier, G. (1994) · Environmental Health Perspectives · doi:10.1289/ehp.94102s1205 · Cited by 106
THE STRUCTURE-ACTIVITY RELATIONSHIPS OF HALOGENATED BIPHENYLS AS ENZYME INDUCERS
Goldstein, J. A. (1979) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1979.tb56599.x · Cited by 104
Anti-estrogen interaction with uterine estrogen receptors. Studies with a radiolabeled anti-estrogen (CI-628).
Katzenellenbogen, B. S., Katzenellenbogen, J. A., Ferguson, E. R., & Krauthammer, N. (1978) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)38159-0 · Cited by 103
Organochlorines in the water and biota of Lake Baikal, Siberia
Kucklick, J. R., Bidleman, T. F., McConnell, L. L., Walla, M. D., & Ivanov, G. P. (1994) · Environmental Science & Technology · doi:10.1021/es00050a006 · Cited by 100
Toxic equivalency factors for dioxin-like PCBs
Ahlborg, U. G., & Hanberg, A. (1994) · Environmental Science and Pollution Research · doi:10.1007/bf02986503 · Cited by 97
A Mechanistic Model of Effects of Dioxin on Thyroid Hormones in the Rat
Kohn, M. C., Sewall, C. H., Lucier, G. W., & Portier, C. J. (1996) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1996.0004 · Cited by 95
Coplanar PCBs in human milk in the Province of Québec, Canada: Are they more toxic than dioxin for breast fed infants?
Dewailly, É., Weber, J. P., Gingras, S., & Laliberté, C. (1991) · Bulletin of Environmental Contamination and Toxicology · doi:10.1007/bf01700935 · Cited by 94
Digestive Tract Absorption of Polychlorinated Dibenzo-p-dioxins, Dibenzofurans, and Biphenyls in a Nursing Infant
McLachlan, M. S. (1993) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1993.1222 · Cited by 94
Hydroxylated Polychlorinated Biphenyl Metabolites Are Anti-estrogenic in a Stably Transfected Human Breast Adenocarcinoma (MCF7) Cell Line
Kramer, V. J., Helferich, W. G., Bergman, Å., Klasson‐Wehler, E., & Giesy, J. P. (1997) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1997.8163 · Cited by 90
Expression of multiple forms of cytochrome P450 mRNAs in primary cultures of rat hepatocytes maintained on matrigel.
Kocarek, T. A., Schuetz, E. G., & Guzelian, P. S. (1993) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)13617-1 · Cited by 90
Inhibition of microsomal and mitochondrial Ca2+-sequestration in rat cerebellum by polychlorinated biphenyl mixtures and congeners
Kodavanti, P. R. S., Ward, T. R., McKinney, J. D., & Tilson, H. A. (1996) · Archives of Toxicology · doi:10.1007/s002040050254 · Cited by 90
Isomer-specific identification of PCB congeners in technical mixtures and environmental samples by HRGC-ECD and HRGC-MSD
Ballschmiter, K., Schäfer, W. M., & Buchert, H. (1987) · Fresenius Zeitschrift für Analytische Chemie · doi:10.1007/bf00474072 · Cited by 88
Determination of polychlorinated biphenyls in human foodstuffs and tissues: Suggestions for a selective congener analytical approach
Jones, K. C. (1988) · The Science of The Total Environment · doi:10.1016/0048-9697(88)90367-1 · Cited by 88
Increased (3H) Phorbol Ester Binding in Rat Cerebellar Granule Cells by Polychlorinated Biphenyl Mixtures and Congeners: Structure-Activity Relationships
Kodavanti, P. R. S., Ward, T. R., McKinney, J. D., & Tilson, H. A. (1995) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1995.1018 · Cited by 87
Alterations in drug metabolism in workers exposed to polychlorinated biphenyls
Alvares, A. P., Fischbein, A. S., Anderson, K. E., & Kappas, A. (1977) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt1977222140 · Cited by 85
Congener‐specific determination of polychlorinated biphenyls and organochlorine pesticides in human milk from Norwegian mothers living in Oslo
Johansen, H. R., Becher, G., Polder, A., & Skaare, J. U. (1994) · Journal of Toxicology and Environmental Health · doi:10.1080/15287399409531870 · Cited by 84
The Challenge Posed by Endocrine-Disrupting Chemicals
Ashby, J., Houthoff, E., Kennedy, S., Stevens, J. T., Bars, R., Jekat, F. W., Campbell, P. M., Miller, J. V., Carpanini, F. M. B., & Randall, G. L. (1997) · Environmental Health Perspectives · doi:10.1289/ehp.97105164 · Cited by 84
Using three-dimensional quantitative structure-activity relationships to examine estrogen receptor binding affinities of polychlorinated hydroxybiphenyls.
Waller, C. L., Minor, D. L., & McKinney, J. D. (1995) · Environmental Health Perspectives · doi:10.1289/ehp.95103702 · Cited by 83
THE STRUCTURE-ACTIVITY RELATIONSHIPS OF HALOGENATED BIPHENYLS AS ENZYME INDUCERS
Goldstein, J. A. (1979) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1979.tb13142.x · Cited by 80
Editorial: Estrogens from Plastic—Are We Being Exposed?
Feldman, D. I. (1997) · Endocrinology · doi:10.1210/endo.138.5.5213 · Cited by 78
Polychlorinated biphenyl levels in the tissues of exposed and nonexposed humans.
Schecter, A. J., Stanley, J. S., Boggess, K. E., Masuda, Y., Mes, J. C., Wolff, M. S., Fürst, P., Fürst, C., Wilson-Yang, K. M., & Chisholm, B. (1994) · Environmental Health Perspectives · doi:10.1289/ehp.94102s1149 · Cited by 78
Relative Binding Affinity-Serum Modified Access (RBA-SMA) Assay Predicts the Relative In Vivo Bioactivity of the Xenoestrogens Bisphenol A and Octylphenol
Nagel, S. C., Saal, F. S. V., Thayer, K. A., et al. (1997) · Environmental Health Perspectives · doi:10.2307/3433065 · Cited by 77
Enzyme Induction and Acute Endocrine Effects in Prepubertal Female Rats Receiving Environmental PCB/PCDF/PCDD Mixtures
Li, M., & Hansen, L. (1996) · Environmental Health Perspectives · doi:10.1289/ehp.96104712 · Cited by 73
Self-citation
Levels of polychlorinated dibenzofurans, dibenzodioxins, PCBS, DDT and DDE, hexachlorobenzene, dieldrin, hexachlorocyclohexanes and oxychlordane in human breast milk from the United States, Thailand, Vietnam, and Germany
Schecter, A. J., Fürst, P., Krüger, C., Meemken, H.-A., Groebel, W., & Constable, J. D. (1989) · Chemosphere · doi:10.1016/0045-6535(89)90154-9 · Cited by 71
Patterns of accumulation of airborne organochlorine contaminants in lichens from the Upper Great Lakes Region of Ontario
Muir, D. C. G., Segstro, M. D., Welbourn, P. M., Toom, D., Eisenreich, S. J., Macdonald, C. R., & Whelpdale, D. M. (1993) · Environmental Science & Technology · doi:10.1021/es00043a022 · Cited by 70
Dietary Exposure of Mink to Carp from Saginaw Bay.
Tillitt, D. E., Gale, R. W., Heaton, J. C. S. N., Bursian, E. E. S. J., & Fish, U. S. (1996) · Cited by 70
Induction of cytochrome P450 3A and heat shock protein by tributyltin in blue crab, Callinectes sapidus
Oberdörster, E., Rittschof, D., & McClellan‐Green, P. D. (1998) · Aquatic Toxicology · doi:10.1016/s0166-445x(97)00067-2 · Cited by 68
Neutrophil Function after Exposure to Polychlorinated Biphenyls in vitro
Ganey, P. E., Sirois, J. E., Denison, M. S., Robinson, J. P., & Roth, R. A. (1993) · Environmental Health Perspectives · doi:10.1289/ehp.93101430 · Cited by 66
Higher concentrations of specific polychlorinated biphenyl congeners in adipose tissue from non-Hodgkin's lymphoma patients compared with controls without a malignant disease
Hardell, L., vanBavel, B., Lindström, G., Fredrikson, M. G., Hagberg, H., Liljegren, G., Nordström, M., & Johansson, B. H. (1996) · International Journal of Oncology · doi:10.3892/ijo.9.4.603 · Cited by 64
Comparison of methods for the gas-chromatographic determination of PCB congeners and chlorinated pesticides in marine reference materials
Schantz, M. M., Parris, R. M., Kurz, J., Ballschmiter, K., & Wise, S. A. (1993) · Analytical and Bioanalytical Chemistry · doi:10.1007/bf00321288 · Cited by 63
Cell-Specific Induction of c-fos Expression in the Pituitary Gland by Estrogen
Allen, D. L., Mitchner, N. A., Uveges, T. E., Nephew, K. P., Khan, S., & Ben‐Jonathan, N. (1997) · Endocrinology · doi:10.1210/en.138.5.2128 · Cited by 63
Toxicokinetic and Toxicodynamic Influences on Endocrine Disruption by Polychlorinated Biphenyls.
Soontornchat, S., Li, M., Cooke, P., & Hansen, L. (1994) · Environmental Health Perspectives · doi:10.1289/ehp.94102568 · Cited by 61
Self-citation
Structure-dependent induction of CYP2B by polychlorinated biphenyl congeners in female Sprague-Dawley rats
Connor, K. T., Safe, S. H., Jefcoate, C. R. E., & Larsen, M. C. (1995) · Biochemical Pharmacology · doi:10.1016/0006-2952(95)02087-x · Cited by 60
Occupational exposure to polychlorinated biphenyls in electrical workers. I. Environmental and blood polychlorinated biphenyls concentrations.
Maroni, M., Colombi, A., Cantoni, S., Ferioli, E., & Foà, V. (1981) · Occupational and Environmental Medicine · doi:10.1136/oem.38.1.49 · Cited by 58
Neutrophil Degranulation and Superoxide Production Induced by Polychlorinated Biphenyls Are Calcium Dependent
Brown, A. P., & Ganey, P. E. (1995) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1995.1062 · Cited by 57
Multiple dose toxicokinetic influence on the estrogenicity of 2,2?,4,4?,5,5?-hexachlorobiphenyl
Li, M., Zhao, Y., & Hansen, L. (1994) · Bulletin of Environmental Contamination and Toxicology · doi:10.1007/bf00199030 · Cited by 56
Self-citation
Role of CYP3A in Ethanol-Mediated Increases in Acetaminophen Hepatotoxicity
Kostrubsky, V. E., Szakacs, J. G., Jeffery, E. H., Wood, S. G., Bement, W. J., Wrighton, S. A., Sinclair, P. R., & Sinclair, J. F. (1997) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1996.8081 · Cited by 54
Environmental Occurrence, Abundance, and Potential Toxicity of Polychlorinated Biphenyl Congeners: Considerations for a Congener-Specific Analysis
McFarland, V., & Clarke, J. U. (1989) · Environmental Health Perspectives · doi:10.2307/3430833 · Cited by 54
Assessment of exposure to polychlorinated biphenyls: Analysis of selected isomers in blood and adipose tissue
Luotamo, M., Järvisalo, J. O., & Aitio, A. (1991) · Environmental Research · doi:10.1016/s0013-9351(05)80095-7 · Cited by 53
The uterotropic activity of commercial and isomerically-pure chlorobiphenyls in the rat.
Ecobichon, D. J., & MacKenzie, D. O. (1974) · PubMed · Cited by 52
Biochemical markers in feral roach (Rutilus rutilus) in relation to the bioaccumulation of organic trace pollutants
van der Oost, R., van Gastel, L., Worst, D., Hanraads, M., Satumalay, K., van Schooten, F., Heida, H., & Vermeulen, N. P. E. (1994) · Chemosphere · doi:10.1016/0045-6535(94)90048-5 · Cited by 51
Induction of CYP2B1 and 3A1, and associated monooxygenase activities by tamoxifen and certain analogues in the livers of female rats and mice
White, L. N. H., Davies, A. M., Smith, L. L., Dawson, S., & Matteis, F. D. (1993) · Biochemical Pharmacology · doi:10.1016/0006-2952(93)90372-4 · Cited by 50
Polychlorobiphenyl (PCB) congeners in striped bass (Morone saxatilis) from marine and estuarine waters of New York State determined by capillary gas chromatography
Bush, B., Streeter, R. W., & Sloan, R. J. (1990) · Archives of Environmental Contamination and Toxicology · doi:10.1007/bf01059812 · Cited by 50
The Role of Oxidative Metabolism in Hexachlorobenzene-Induced Porphyria and Thyroid Hormone Homeostasis: A Comparison with Pentachlorobenzene in a 13-Week Feeding Study
den Besten, C., Bennik, M. H. J., Bruggeman, I. M., Schielen, P. C. J. I., Kuper, C. F., Brouwer, A., Koeman, J. H., Vos, J. G., & Vanbladeren, P. J. (1993) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1993.1059 · Cited by 48
CB pattern in the harbour porpoise: Bioaccumlation, metabolism and evidence for cytochrome p450 IIB activity
Bruhn, R., Kannan, N., Petrick, G., Schutz-Bull, D. E., & Duinker, J. C. (1995) · Chemosphere · doi:10.1016/0045-6535(95)00221-s · Cited by 48
Analysis of the molecular pharmacology of estrogen receptor agonists and antagonists provides insights into the mechanism of action of estrogen in bone
McDonnell, D. P., & Norris, J. D. (1997) · Osteoporosis International · doi:10.1007/bf01674810 · Cited by 47
Induction of hepatic microsomal drug-metabolizing enzymes by methylsulphonyl metabolites of polychlorinated biphenyl congeners in rats
Kato, Y., Haraguchi, K., Kawashima, M., Yamada, S., Masuda, Y., & Kimura, R. (1995) · Chemico-Biological Interactions · doi:10.1016/0009-2797(94)03564-o · Cited by 46
AN EXPANDED APPROACH TO THE STUDY AND MEASUREMENT OF PCBs AND SELECTED PLANAR HALOGENATED AROMATIC ENVIRONMENTAL POLLUTANTS
Stalling, D. L., Huckins, J. N., Petty, J. D., Johnson, J. L., & Sanders, H. O. (1979) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1979.tb56592.x · Cited by 46
Analysis of polychlorobiphenyl congeners in Wisconsin fish
Maack, L., & Sonzogni, W. C. (1988) · Archives of Environmental Contamination and Toxicology · doi:10.1007/bf01061977 · Cited by 45
Endocrine System
Capen, C. C., DeLellis, R. A., & Yarrington, J. T. (1991) · Elsevier eBooks · doi:10.1016/b978-0-12-330220-5.50026-7 · Cited by 45
Concentrations of Blood and Hair Mercury and Serum PCBs in an Ojibwa Population That Consumes Great Lakes Region Fish
Gerstenberger, S., Tavris, D. R., Hansen, L. K., Pratt-Shelley, J., & Dellinger, J. A. (1997) · Journal of Toxicology Clinical Toxicology · doi:10.3109/15563659709043370 · Cited by 44
Self-citation
Interlaboratory studies of the determination of selected chlorobiphenyl congeners with capillary gas chromatography using splitless‐ and on‐column injection techniques
Tuinstra, L. G. M. T., Roos, A. H., Griepink, B. F. A., & Wells, D. E. (1985) · Journal of High Resolution Chromatography · doi:10.1002/jhrc.1240080824 · Cited by 40
A congener specific method for the analysis of polychlorinated biphenyls (PCBs) in human milk
Duarte‐Davidson, R., Burnett, V., Waterhouse, K. S., & Jones, K. C. (1991) · Chemosphere · doi:10.1016/0045-6535(91)90101-i · Cited by 38
Toxicity equivalency factors for PCBs?
Barnes, D., Alford-Stevens, A., Birnbaum, L. S., Kutz, F. W., Wood, W., & Patton, D. (1991) · PubMed · Cited by 36
Expression of Ryanodine Receptors in the Pituitary Gland: Evidence for a Role in Gonadotropin-Releasing Hormone Signaling
Sundaresan, S., Weiss, J., Bauer-Dantoin, A. C., & Jameson, J. L. (1997) · Endocrinology · doi:10.1210/endo.138.5.5153 · Cited by 34
Responses of Prepubertal Female Rats to Environmental PCBs with High and Low Dioxin Equivalencies
Li, M. (1996) · Fundamental and Applied Toxicology · doi:10.1006/faat.1996.0166 · Cited by 32
Influence of Harbor Contamination on the Level and Composition of Polychlorinated Biphenyls in Produce in Greater New Bedford, Massachusetts
Cullen, A. C., Vorhees, D. J., & Altshul, L. (1996) · Environmental Science & Technology · doi:10.1021/es9505614 · Cited by 32
Phenobarbital Induction of CYP2B1, CYP2B2, and CYP3A1 in Rat Liver: Genetic Differences in a Common Regulatory Mechanism
Larsen, M. C., & Jefcoate, C. R. E. (1995) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1995.1419 · Cited by 31
Distribution, Dilution, and Elimination of Polychlorinated Biphenyl Analogs in Growing Swine
Hansen, L., & Welborn, M. E. (1977) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600660410 · Cited by 30
Self-citation
Selective Retention of Hydroxylated PCB Metabolites in Blood
Bergman, Å., Klasson‐Wehler, E., & Kuroki, H. (1994) · Environmental Health Perspectives · doi:10.2307/3432042 · Cited by 30
MORPHOMETRY CHANCES IN THE PREPUBERTAL FEMALE RAT THYROID GLAND FOLLOWING ACUTE EXPOSURE TO 2,2′,4,4′-TETRACHLOROBIPHENYL AND AROCLOR 1242
Saeed, A., & Hansen, L. G. (1997) · Journal of Toxicology and Environmental Health · doi:10.1080/00984109708984040 · Cited by 30
Self-citation
PCB metabolism, persistence, and health effects after occupational exposure: implications for risk assessment
Brown, J. F., Lawton, R. W., & Morgan, C. (1994) · Chemosphere · doi:10.1016/0045-6535(94)90396-4 · Cited by 30
The human population - An ultimate receptor for aquatic contaminants
Humphrey, H. E. B. (1987) · Springer eBooks · doi:10.1007/978-94-009-4053-6_8 · Cited by 29
Altered in vivo toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (tcdd) in c-src deficient mice
Matsumura, F., Enan, E. E., Dunlap, D. Y., Pinkerton, K. E., & Peake, J. L. (1997) · Biochemical Pharmacology · doi:10.1016/s0006-2952(97)00036-1 · Cited by 28
Environmental polychlorinated biphenyls: Acute toxicity of landfill soil extract to female prepubertal rats
Hansen, L., Li, M., Saeed, A., & Bush, B. (1995) · Archives of Environmental Contamination and Toxicology · doi:10.1007/bf00212498 · Cited by 27
Self-citation
Vascular plants as sensitive indicators of lead and PCB transport from local sources in the Canadian Arctic
Dushenko, W. T., Grundy, S., & Reimer, K. J. (1996) · The Science of The Total Environment · doi:10.1016/0048-9697(96)05154-6 · Cited by 26
POLYCHLORINATED BIPHENYL CONGENERS AND SELECTED ORGANOCHLORINES IN LAKE SUPERIOR FISH, USA
Gerstenberger, S., Gallinat, M. P., & Dellinger, J. A. (1997) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5620161104 · Cited by 25
Using Three-Dimensional Quantitative Structure-Activity Relationships to Examine Estrogen Receptor Binding Affinities of Polychlorinated Hydroxybiphenyls
Waller, C. L., Minor, D. L., & McKinney, J. D. (1995) · Environmental Health Perspectives · doi:10.2307/3432862 · Cited by 24
Editorial: Estrogens from Plastic--Are We Being Exposed?
Feldman, D. (1997) · Endocrinology · doi:10.1210/en.138.5.1777 · Cited by 24
Determination of chlorobiphenyls, with the separation of non-ortho, mono-ortho and di-ortho chloro congeners in fish and sea mammals
Wells, D. E., & Echarri, I. (1994) · Analytica Chimica Acta · doi:10.1016/0003-2670(94)85089-5 · Cited by 24
PCB levels in bird blood and relationship to MFO responses
Marsili, L., Fossi, M. C., Casini, S., & Focardi, S. E. (1996) · Chemosphere · doi:10.1016/0045-6535(96)00222-6 · Cited by 23
SELECTIVE ACCUMULATION AND DEPLETION OF POLYCHLORINATED BIPHENYL COMPONENTS: FOOD ANIMAL IMPLICATIONS
Hansen, L. G. (1979) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1979.tb13148.x · Cited by 23
Self-citation
MORPHOMETRIC CHANGES IN THE PREPUBERTAL FEMALE RAT THYROID GLAND FOLLOWING ACUTE EXPOSURE TO 2,2',4,4'-TETRACHLOROBIPHENYL AND AROCLOR 1242
Saeed, A., & Hansen, L. G. (1997) · Journal of Toxicology and Environmental Health · doi:10.1080/009841097159944 · Cited by 22
Self-citation
Subchronic Dietary Exposure to Aroclor 1254 in Rats: Accumulation of PCBs in Liver, Blood, and Adipose Tissue and Its Relationship to Induction of Various Hepatic Drug-Metabolizing Enzymes
Dragnev, K. H., Beebe, L. E., Jones, C. R., Fox, S. D., Thomas, P. E., Nims, R. W., & Lubet, R. A. (1994) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1994.1055 · Cited by 21
Uterotropic and enzyme induction effects of 2,2?,5-trichlorobiphenyl
Li, M., & Hansen, L. (1995) · Bulletin of Environmental Contamination and Toxicology · doi:10.1007/bf00192590 · Cited by 21
Self-citation
Chlorobiphenyl (PCB) composition of extracts of subsurface soil, superficial dust and air from a contaminated landfill
Hansen, L., Green, D., Cochran, J., Vermette, S., & Bush, B. (1997) · Fresenius Journal of Analytical Chemistry · doi:10.1007/s002160050186 · Cited by 20
Self-citation
Proposed PCB Congener Groupings for Epidemiological Studies
Wolff, M. S., Camann, D., Gammon, M. D., & Stellman, S. D. (1997) · Environmental Health Perspectives · doi:10.2307/3433043 · Cited by 19
Polychlorinated biphenyl congeners in adipose tissue lipid and serum of past and present transformer repair workers and a comparison group*1
Fait, A. (1989) · Fundamental and Applied Toxicology · doi:10.1016/0272-0590(89)90060-2 · Cited by 18
Specimc polychlorinated biphenyl congener distribution in breast milk of Canadian women
Mes, J., Davies, D. J., Doucet, J., Weber, D. F., & Mullen, E. M. (1993) · Environmental Technology · doi:10.1080/09593339309385324 · Cited by 18
Critical evaluation of methods for detection and assessment of estrogenic compounds in mammals: strengths and limitations for application to risk assessment
Kupper, D. (1987) · Reproductive Toxicology · doi:10.1016/0890-6238(87)90010-4 · Cited by 17
The Regulation by Gender, Strain, Dose, and Feeding Status of the Induction of Multiple Forms of Cytochrome P450 Isozymes in Rat Hepatic Microsomes by 2,4,5,2′,4′,5′-Hexachlorobiphenyl
Ikegwuonu, F. I., Ganem, L. G., Larsen, M. C., Shen, X., & Jefcoate, C. R. E. (1996) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1996.0140 · Cited by 17
Glass Capillary Gas Chromatography for Sensitive, Accurate Polychlorinated Biphenyl Analysis
Bush, B., Connor, S., & Snow, J. (1982) · Journal of AOAC INTERNATIONAL · doi:10.1093/jaoac/65.3.555 · Cited by 17
The Challenge Posed by Endocrine-Disrupting Chemicals
Ashby, J., Houthoff, E., Kennedy, S., et al. (1997) · Environmental Health Perspectives · doi:10.2307/3433233 · Cited by 17
Persistence of 2,3,6-substituted pentachlorobiphenyls in the lung parenchyma: A new structure-dependent tissue localization of polychlorinated biphenyls in mice
Brandt, I., Mohammed, A., & Slanina, P. (1981) · Toxicology · doi:10.1016/0300-483x(81)90146-3 · Cited by 16
Concentrations of PCB congeners in sera from workers with past and present exposure
Luotamo, M., Patterson, D. G., Needham, L. L., & Aitio, A. (1993) · Chemosphere · doi:10.1016/0045-6535(93)90290-l · Cited by 15
Species and congener specific induction of hepatic cytochrome P4504A by polychlorinated biphenyls
Huang, S., & Gibson, G. G. (1992) · Biochemical Pharmacology · doi:10.1016/0006-2952(92)90588-a · Cited by 15
Neutrophil Function after Exposure to Polychlorinated Biphenyls in vitro
Ganey, P. E., Sirois, J. E., Denison, M. S., et al. (1993) · Environmental Health Perspectives · doi:10.2307/3431901 · Cited by 15
Expression and inducibility of cytochrome P450 proteins in the liver of chick embryo
Machala, M., Nezveda, K., Irizar, A., Bu-Abbas, A., & Ioannides, C. (1996) · Archives of Toxicology · doi:10.1007/s002040050358 · Cited by 12
Enzyme Induction and Acute Endocrine Effects in Prepubertal Female Rats Receiving Environmental PCB/PCDF/PCDD Mixtures
Li, M., & Hansen, L. G. (1996) · Environmental Health Perspectives · doi:10.2307/3433216 · Cited by 10
Self-citation
Toxicokinetics of 2,2′,4,4′- and 3,3′,4,4′-Tetrachlorobiphenyl in House Flies Following Topical Administration
Saghir, S. A., KORITZ, G. D., & Hansen, L. (1994) · Pesticide Biochemistry and Physiology · doi:10.1006/pest.1994.1037 · Cited by 7
Self-citation
Polychlorinated biphenyl (PCB) congener effects on the longevity of the housefly
Wm, T., Hansen, L., & Schaeffer, D. J. (1992) · Bulletin of Environmental Contamination and Toxicology · doi:10.1007/bf00197490 · Cited by 7
Self-citation
Characterization of the polychlorinated biphenyls in the sediments of Woods Pond: Evidence for microbial dechlorination of Aroclor 1260 in situ
Bedard, D. L., & May, R. J. (1996) · Environmental Pollution · doi:10.1016/s0269-7491(97)84225-x · Cited by 7
Capillary Gas Chromatographic-Mass Spectrometric Determination of Individual Chlorobiphenyls in Technical Aroclors
Tuinstra, L. G. M. T., & Traag, W. A. (1983) · Journal of AOAC INTERNATIONAL · doi:10.1093/jaoac/66.3.708 · Cited by 7
QUALITY ASSURANCE QUALITY CONTROL PROCEDURES FOR CHLORINATED HYDROCARBONS IN HUMAN BREAST ADIPOSE TISSUE
Tes, S. A. E. J. D. (1996) · Journal of Toxicology and Environmental Health · doi:10.1080/009841096160646 · Cited by 6
Effects of polychlorinated biphenyls (PCBs) on hepatic enzyme induction, uterotropic responses, and thyroid hormone levels in prepubertal female rats
Li, M. (1996) · Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign) · Cited by 5
Accumulation and depletion of polychlorinated biphenyl (PCB) congeners in the housefly (Musca domestica, L.)
Hansen, L., & Storr-Hansen, E. (1992) · Bulletin of Environmental Contamination and Toxicology · doi:10.1007/bf00197489 · Cited by 5
Self-citation
Polychlorinated Biphenyl Congeners in Adipose Tissue Lipid and Serum of Past and Present Transformer Repair Workers and a Comparison Group
Fait, A., GROSSMAN, E., Self, S. G., Jeffries, J., PELLIZZAR, E. D., & Emmett, E. A. (1989) · Toxicological Sciences · doi:10.1093/toxsci/12.1.42 · Cited by 1

Flagged first, then by citations

15 of the 175 references couldn’t be matched to a known paper.

Sorted by citations

Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement
Diamanti-Kandarakis, E., Bourguignon, J.-P., Giudice, L. C., Hauser, R., Prins, G. S., Soto, A. M., Zoeller, R. T., & Gore, A. C. (2009) · Endocrine Reviews · doi:10.1210/er.2009-0002 · Cited by 4,585
The 2005 World Health Organization Reevaluation of Human and Mammalian Toxic Equivalency Factors for Dioxins and Dioxin-like Compounds
Van den Berg, M., Birnbaum, L. S., Denison, M., De Vito, M., Farland, W., Feeley, M., Fiedler, H., Hakansson, H., Hanberg, A., Haws, L., et al. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfl055 · Cited by 3,785
Endocrine-Disrupting Chemicals and Public Health Protection: A Statement of Principles from The Endocrine Society
Zoeller, R. T., Brown, T. R., Doan, L. L., Gore, A. C., Skakkebæk, N. E., Soto, A. M., Woodruff, T. J., & Saal, F. S. V. (2012) · Endocrinology · doi:10.1210/en.2012-1422 · Cited by 1,185
Effects of PCB exposure on neuropsychological function in children.
Schantz, S. L., Widholm, J. J., & Rice, D. C. (2003) · Environmental Health Perspectives · doi:10.1289/ehp.5461 · Cited by 503
Metabolism and metabolites of polychlorinated biphenyls
Grimm, F. A., Hu, D., Kania‐Korwel, I., Lehmler, H., Ludewig, G., Hornbuckle, K. C., Duffel, M. W., Bergman, Å., & Robertson, L. W. (2015) · Critical Reviews in Toxicology · doi:10.3109/10408444.2014.999365 · Cited by 445

See all 336

Authors: Hansen, L. G.
Venue: Environmental Health Perspectives
Publisher: JSTOR
Published: 1998-02
Volume: 106
Issue: suppl 1
Pages: 171
ISSN: 0091-6765 (ISSN-L)
DOI: 10.2307/3433919
OpenAlex: W2073813648
Cited by: 336
References: 175
Citations by year: 2026: 1 · 2025: 3 · 2024: 2 · 2023: 5 · 2022: 5 · 2021: 3 · 2020: 10 · 2019: 4 · 2018: 8 · 2017: 7 · 2016: 5 · 2015: 10 · 2014: 16 · 2013: 17 · 2012: 11
FWCI: 3.32
Type: journal article
Language: en
Open access: gold
doi.org
Licence: public-domain
Locations: Environmental Health Perspectives (publishedVersion, public-domain)
Environmental Health Perspectives (publishedVersion)
PubMed (publishedVersion)
Topics: Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
Keywords: polychlorinated biphenyls, PCB congeners, risk assessment, aryl hydrocarbon receptor agonists, PCB mixtures, hazard characterization, non-Hodgkin lymphoma, early life exposure, data harmonization
MeSH terms: Animals, Body Burden, Cytochrome P-450 Enzyme System, Enzyme Induction, Humans, Polychlorinated Biphenyls, Thyroid Hormones, Receptors, Aryl Hydrocarbon, Risk Assessment

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Stepping Backward to Improve Assessment of PCB Congener Toxicities

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks