Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans

Zhang, Xinmei, Yeung, Dennis C.Y., Karpisek, Michal, Stejskal, David, Zhou, Zhi-Guang, Liu, Feng, Wong, Rachel L.C., Chow, Wing-Sun +3 more·2008·Diabetes

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  3. Association of serum fibroblast growth factor 21 and urinary glucose excretion in hospitalized patients with type 2 diabetes
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  5. Plasma Tsukushi Concentration Is Associated with High Levels of Insulin and FGF21 and Low Level of Total Cholesterol in a General Population without Medication
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  7. Acromegaly is associated with high fibroblast growth factor-21 levels
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  9. Serum FGF21 in boys with idiopathic short stature: relationship to lipid profile, onset of puberty and growth*
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  13. Fibroblast Growth Factor 21: Mechanisms, Therapeutic Potential, and Clinical Translation in Metabolic Dysfunction
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  14. Investigation of the Characteristics of Crimean Congo Hemorrhagic Fever Cases Reported in Afyonkarahisar Province
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  15. AOX delays the onset of the lethal phenotype in a mouse model of Uqcrh (complex III) disease
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  16. Activin E upregulates uncoupling protein 1 and fibroblast growth factor 21 in brown adipocytes
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  17. Treating metabolic dysfunction‐associated steatohepatitis: The fat‐trimming FGF21 approach
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  18. Hepatokine leukocyte cell‐derived chemotaxin 2 as a biomarker of insulin resistance, liver enzymes, and metabolic dysfunction‐associated steatotic liver disease in the general population
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  19. Circulating fibroblast growth factor 21 is associated with blood pressure in the Chinese population: a community-based study
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  25. Treatment with FGFR2-IIIc monoclonal antibody suppresses weight gain and adiposity in KKAy mice
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  27. Plasma FGF21 Levels Are Not Associated with Weight Loss or Improvements in Metabolic Health Markers upon 12 Weeks of Energy Restriction: Secondary Analysis of an RCT
    Anouk Gijbels, Sophie Schutte, Diederik Esser, Charlotte C. J. R. Michielsen, Els Siebelink, Monica Mars, Marco Mensink, Lydia A. Afman · 2022 · Nutrients
  28. High circulating fibroblast growth factor-21 levels as a screening marker in fatty pancreas patients
    Fei Han, Ling Yin, Xiaoping Yu, Renyan Xu, Mingxiang Tian, Xinnong Liu, Lu Zhou, Liang‐Hao Hu, Weijuan Gong, Weiming Xiao et al. · 2023 · PeerJ
  29. Hepatic miR‑215 target Rictor and modulation of hepatic insulin signalling in rats
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  30. NEW INSIGHTS INTO BROWN ADIPOSE TISSUE AS A PHARMACOLOGICAL TARGET IN OBESITY
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  32. The role of the glucagon‐FGF21 axis in improving beta cell function during glucose intolerance and SGLT2 inhibition
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  33. Maternal obesity impairs fetal brown adipogenesis by attenuating fetal FGF21 signaling
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  34. Plasma Levels of Fibroblast Growth Factor 21 and Adverse Kidney Outcomes
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  35. FGF21 restores metabolic function in Alzheimer’s disease via activation of PI3K/Akt signaling
    Feng Zhao, Hui Yang, Huamei Liu, Heming Yu, Yang Zhao · 2025 · Neurological Research
  36. Can Myokines Serve as Supporters of Muscle–Brain Connectivity in Obesity and Type 2 Diabetes? Potential of Exercise and Nutrition Interventions
    Heaji Lee, Yunsook Lim · 2025 · Nutrients
  37. Whole-brain Mapping Reveals Diet-dependent Neuronal Activation and Selective Resistance to Exogenous FGF21
    Jieyi Meng, Xi Chen, Yi Zhu · 2025 · Endocrinology
  38. Exploring the correlation between serum fibroblast growth factor-21 levels and Sarcopenia: a systematic review and meta-analysis
    Hao Liu, Xiayun He, Xiaoyan Deng, Jing-Lu Yan · 2023 · BMC Musculoskeletal Disorders
  39. The association of FGF-21 with the risk of newly diagnosed type-2 diabetes mellitus: a cross-sectional study in Southern China
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  40. Fibroblast Growth Factor 21 Predicts Type 2 Diabetes in Taiwanese
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  41. Mitochondrial Respiratory Disorders: A Perspective on their Metabolite Biomarkers and Implications for Clinical Diagnosis and Therapeutic Intervention.
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  42. Hepatic Fat Content Is Associated with Fasting-Induced Fibroblast Growth Factor 21 Secretion in Mice Fed Soy Proteins
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  43. Bibliometric analysis of fibroblast growth factor 21 research over the period 2000 to 2021
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  44. Sitagliptin reduces FAP-activity and increases intact FGF21 levels in patients with newly detected glucose abnormalities
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  45. Serum Level of Fibroblast Growth Factor 21 in Type 2 Diabetic Patients with and without Metabolic Syndrome
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  46. Association of circulating FGF-21 levels in the first week of life and postnatal growth in hospitalized preterm infants
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  47. Fibroblast growth factor-21 levels in metabolic syndrome: Another instrument in a widening tool belt?
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  53. BIOMARKER QUANTITATION: ANALYTICAL CONSIDERATIONS FOR LIGAND BINDING ASSAY REGRESSION CURVES AND QUALITY CONTROL SAMPLES
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  83. The effects of SGLT2 inhibitors on metabolic phenotype and FGF-21 expression from the adipose tissue and the liver are less pronounced in ob/ob mice
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  84. Serum FGF21 Levels in Obese Korean Children and Adolescents (J Obes Metab Syndr 2017;26:204-9)
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  87. Fibroblast growth factor-21: A link for glucose homeostasis
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  91. Soluble angiotensin-converting enzyme 2 association with lipid metabolism
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  94. Fibroblast Growth Factor 21 as a Novel Metabolic Regulator
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  97. Mitochondrial and Stress-Related Psychobiological Regulation of FGF21 in Humans
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  100. Serum fibroblast growth factor 21: Lack of association with gestational diabetes and pregnancy outcomes
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