Cited by 407Diabetes Management and EducationDiabetes Management and ResearchMedication Adherence and Compliance

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Correlates of Insulin Injection Omission

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Peyrot, Mark, Rubin, Richard R., Kruger, Davida F., Travis, Luther B.·2010·Diabetes Care

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Abstract

OBJECTIVE: The purpose of this study was to assess factors associated with patient frequency of intentionally skipping insulin injections. RESEARCH DESIGN AND METHODS: Data were obtained through an Internet survey of 502 U.S. adults self-identified as taking insulin by injection to treat type 1 or type 2 diabetes. Multiple regression analysis assessed independent associations of various demographic, disease, and injection-specific factors with insulin omission. RESULTS: Intentional insulin omission was reported by more than half of respondents; regular omission was reported by 20%. Significant independent risk factors for insulin omission were younger age, lower income and higher education, type 2 diabetes, not following a healthy diet, taking more daily injections, interference of injections with daily activities, and injection pain and embarrassment. Risk factors differed between type 1 and type 2 diabetic patients, with diet nonadherence more prominent in type 1 diabetes and age, education, income, pain, and embarrassment more prominent in type 2 diabetes. CONCLUSIONS: Whereas most patients did not report regular intentional omission of insulin injections, a substantial number did. Our findings suggest that it is important to identify patients who intentionally omit insulin and be aware of the potential risk factors identified here. For patients who report injection-related problems (interference with daily activities, injection pain, and embarrassment), providers should consider recommending strategies and tools for addressing these problems to increase adherence to prescribed insulin regimens. This could improve clinical outcomes.

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“…month Olamoyegun et al. (2018) 44 27.2% of PwD missed insulin doses intentionally (5.2% often missed) and 20.2% missed doses unintentionally (2.8% often) Peyrot et al. (2010) 24,a 57% of PwD skipped insulin injections they knew they should take Peyrot et al. (2012) 16 33.2% of PwD (global GAPP1…”
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Authors: Peyrot, M., Rubin, R. R., Kruger, D. F., & Travis, L. B.
Affiliations: Johns Hopkins University (US)
Henry Ford Health (US)
The University of Texas Medical Branch at Galveston (US)
Corresponding author: Peyrot, Mark
ORCID: Peyrot, Mark
Kruger, Davida F.
Venue: Diabetes Care
Publisher: American Diabetes Association
Published: 2010-02-01
Volume: 33
Issue: 2
Pages: 240-245
ISSN: 0149-5992 (ISSN-L)
1935-5548
DOI: 10.2337/dc09-1348
PMC: PMC2809256
OpenAlex: W2103829708
Cited by: 407
References: 24
Citations by year: 2026: 14 · 2025: 15 · 2024: 17 · 2023: 18 · 2022: 18 · 2021: 17 · 2020: 21 · 2019: 30 · 2018: 33 · 2017: 31 · 2016: 38 · 2015: 29 · 2014: 33 · 2013: 37 · 2012: 22
FWCI: 22.33
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-nd
Locations: Diabetes Care (publishedVersion, cc-by-nc-nd)
PubMed Central (publishedVersion, cc-by-nc-nd)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
Keywords: insulin omission, insulin injection, type 1 diabetes, type 2 diabetes, insulin adherence, injection pain, socioeconomic factors, age, insulin regimens
MeSH terms: Adult, Aged, Behavior, Cardiovascular Diseases, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetic Angiopathies, Ethnicity, Female, Health Surveys, Humans, Hypertension, Hypoglycemic Agents, Income, Insulin, Male, Middle Aged, Perception, Regression Analysis, Risk-Taking, Self Care, Racial Groups

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