Insulin adherence in patients with diabetes: risk factors for injection omission
Abstract
Aims The purpose of this study was to evaluate adherence to insulin therapy in patients with diabetes. The underlying factors affecting insulin injection omission among patients with type 1 or 2 diabetes were also investigated.Methods This cross-sectional study has been conducted on 507 patients with diabetes. Adherence to insulin therapy was measured by the 8-Item Moriskey Medication Adherence Scale (MMS) and the autocompliance method. Furthermore, socio-demographic, disease and injection-related barriers to insulin injection were assessed.Results Based on the Morisky Green test, 14.3% and 28.8% of patients with type 1 and 2 diabetes respectively had low adherence to insulin therapy. However, almost all patients were adherent according to the autocompliance method. Different factors showed a significant association with insulin compliance in both groups.Conclusions The current study suggests acceptable adherence to insulin therapy among patients with type 1, and poor adherence in patients with type 2, diabetes. Our findings regarding barriers with significant effect on insulin adherence may be useful to identify patients at risk for low compliance, and to guide the design of proper strategies to improve adherence and the consequential clinical outcomes.
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For people with insulin-requiring diabetes, dosing instructions may be complex and confusing.
“For people with insulin-requiring diabetes, dosing instructions may be complex and confusing (3-6).”
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- Authors
- Farsaei, S., Radfar, M., Heydari, Z., Abbasi, F., & Qorbani, M.
- Affiliations
- Isfahan University of Medical Sciences (IR)
- Endocrinology and Metabolism Clinical Sciences Institute (IR)
- Children's Medical Center (IR)
- Iran University of Medical Sciences (IR)
- Corresponding author
- Radfar, Mania
- Venue
- Primary care diabetes
- Publisher
- Elsevier BV
- Published
- 2014-12
- Volume
- 8
- Issue
- 4
- Pages
- 338-345
- ISSN
- 1751-9918 (ISSN-L)
- OpenAlex
- W1963717917
- Cited by
- 106
- References
- 34
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 8 · 2023: 9 · 2022: 13 · 2021: 8 · 2020: 9 · 2019: 14 · 2018: 13 · 2017: 9 · 2016: 10 · 2015: 3
- FWCI
- 7.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Primary care diabetes (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Tehran University of Medical Sciences (10736-33-02-89)
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- insulin adherence, insulin therapy, type 1 diabetes, type 2 diabetes, medication adherence, Morisky Medication Adherence Scale, risk factors
- MeSH terms
- Adolescent, Adult, Aged, Child, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Female, Humans, Hypoglycemic Agents, Injections, Insulin, Health Knowledge, Attitudes, Practice, Male, Middle Aged, Surveys and Questionnaires, Risk Factors, Medication Adherence, Young Adult
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