Cited by 875Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and MetabolismRegulation of Appetite and Obesity

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Adiponectin Expression From Human Adipose Tissue

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Kern, Philip A., Di Gregorio, Gina B., Lu, Tong, Rassouli, Negah, Ranganathan, Gouri·2003·Diabetes

DOI 10.2337/diabetes.52.7.1779

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Abstract

Adiponectin is a 29-kDa adipocyte protein that has been linked to the insulin resistance of obesity and lipodystrophy. To better understand the regulation of adiponectin expression, we measured plasma adiponectin and adipose tissue adiponectin mRNA levels in nondiabetic subjects with varying degrees of obesity and insulin resistance. Plasma adiponectin and adiponectin mRNA levels were highly correlated with each other (r = 0.80, P < 0.001), and obese subjects expressed significantly lower levels of adiponectin. However, a significant sex difference in adiponectin expression was observed, especially in relatively lean subjects. When men and women with a BMI <30 kg/m2 were compared, women had a twofold higher percent body fat, yet their plasma adiponectin levels were 65% higher (8.6 ± 1.1 and 14.2 ± 1.6 μg/ml in men and women, respectively; P < 0.02). Plasma adiponectin had a strong association with insulin sensitivity index (SI) (r = 0.67, P < 0.0001, n = 51) that was not affected by sex, but no relation with insulin secretion. To separate the effects of obesity (BMI) from SI, subjects who were discordant for SI were matched for BMI, age, and sex. Using this approach, insulin-sensitive subjects demonstrated a twofold higher plasma level of adiponectin (5.6 ± 0.6 and 11.2 ± 1.1 μg/ml in insulin-resistant and insulin-sensitive subjects, respectively; P < 0.0005). Adiponectin expression was not related to plasma levels of leptin or interleukin-6. However, there was a significant inverse correlation between plasma adiponectin and tumor necrosis factor (TNF)-α mRNA expression (r = −0.47, P < 0.005), and subjects with the highest levels of adiponectin mRNA expression secreted the lowest levels of TNF-α from their adipose tissue in vitro. Thus, adiponectin expression from adipose tissue is higher in lean subjects and women, and is associated with higher degrees of insulin sensitivity and lower TNF-α expression.

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Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
Hotamisligil, G. S., Shargill, N. S., & Spiegelman, B. M. (1993) · Science · doi:10.1126/science.7678183 · Cited by 7,518
Prevalence and trends in obesity among US adults, 1999–2000
Flegal, K. M. (2002) · JAMA · doi:10.1001/jama.288.14.1723 · Cited by 6,190
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
Yamauchi, T., Kamon, J., Waki, H., Terauchi, Y., Kubota, N., Hara, K., Mori, Y., Ide, T., Murakami, K., Tsuboyama-Kasaoka, N., et al. (2001) · Nature Medicine · doi:10.1038/90984 · Cited by 4,915
A simple, rapid, and sensitive DNA assay procedure
Labarca, C. G., & Paigen, K. (1980) · Analytical Biochemistry · doi:10.1016/0003-2697(80)90165-7 · Cited by 4,870
Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity
Arita, Y., Kihara, S., Ouchi, N., Takahashi, M., Maeda, K., Miyagawa, J.-I., Hotta, K., Shimomura, I., Nakamura, T., Miyaoka, K., et al. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.0255 · Cited by 4,856
Insulin Resistance: A Multifaceted Syndrome Responsible for NIDDM, Obesity, Hypertension, Dyslipidemia, and Atherosclerotic Cardiovascular Disease
DeFronzo, R. A., & Ferrannini, E. (1991) · Diabetes Care · doi:10.2337/diacare.14.3.173 · Cited by 4,555
Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.
Hotamisligil, G. S., Arner, P., Caro, J. F., Atkinson, R. L., & Spiegelman, B. M. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117936 · Cited by 3,543
Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance and Hyperinsulinemia
Weyer, C., Funahashi, T., Tanaka, S., Hotta, K., Matsuzawa, Y., Pratley, R. E., & Tataranni, P. A. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.5.7463 · Cited by 3,541
Obesity and insulin resistance
Kahn, B. B., & Flier, J. S. (2000) · Journal of Clinical Investigation · doi:10.1172/jci10842 · Cited by 3,345
A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes
Scherer, P. E., Williams, S. P., Fogliano, M., Baldini, G., & Lodish, H. F. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.45.26746 · Cited by 3,238

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Shikany, J. M., Lewis, C. E., Freedman, B. I., Arnett, D. K., Leiendecker‐Foster, C., Jones, T. L., Redden, D. T., & Oberman, A. (2007) · Metabolism · doi:10.1016/j.metabol.2007.03.020 · Cited by 10
Plasma adiponectin is modestly decreased during 24‐hour insulin infusion but not after inhibition of lipolysis by Acipimox
Dullaart, R. P. F., Riemens, S. C., Meinardi, J. R., Wolffenbuttel, B. H. R., & Sluiter, W. J. (2005) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/00365510500209090 · Cited by 10
Effects of weight loss and pharmacotherapy on inflammatory markers of cardiovascular disease
Miller, W. M., Janosz, K. E. N., Yanez, J., & McCullough, P. A. (2005) · Expert Review of Cardiovascular Therapy · doi:10.1586/14779072.3.4.743 · Cited by 10
Adiponectin as a sepsis biomarker in dogs: Diagnostic and prognostic value
Torrente, C., Manzanilla, E. G., Bosch, L., Villaverde, C., Pastor, J., Fernández, R. R. D. G. I., & Tvarijonaviciute, A. (2020) · Veterinary Clinical Pathology · doi:10.1111/vcp.12858 · Cited by 9
Deficiency of exchange protein directly activated by cAMP (EPAC)-1 in mice augments glucose intolerance, inflammation, and gut dysbiosis associated with Western diet
Virwani, P. D., Cai, L., Yeung, P. K. K., Qian, G., Chen, Y., Zhou, L., Wong, J. W. H., Wang, Y., Ho, J. W. K., Lau, K. K., et al. (2022) · Microbiome · doi:10.1186/s40168-022-01366-0 · Cited by 10
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Elevated fasting serum insulin level predicts future development of hypertension
Park, S. K., Jung, J. Y., Choi, W. J., Kim, Y. H., Kim, H. S., Ham, W. T., Shin, H., & Ryoo, J. (2014) · International Journal of Cardiology · doi:10.1016/j.ijcard.2014.01.087 · Cited by 9
Relationships of Total Adiponectin and Molecular Weight Fractions of Adiponectin With Free Testosterone in African Men and Premenopausal Women
Cui, J., Wu, X., Andrel, J. A., & Falkner, B. E. (2010) · Journal of Clinical Hypertension · doi:10.1111/j.1751-7176.2010.00383.x · Cited by 9
HUBUNGAN INDEKS MASSA TUBUH DENGAN KADAR LEPTIN DAN ADIPONEKTIN
Subarjati, A., & Nuryanto, N. (2015) · Journal of Nutrition College · doi:10.14710/jnc.v4i4.10121 · Cited by 9
Differences in Adipose Tissue and Lean Mass Distribution in Patients with Collagen VI Related Myopathies Are Associated with Disease Severity and Physical Ability
Rodríguez, M. A., Barquero, L. M. D. R., Ortez, C., Jou, C., Vigo, M., Medina, J., Febrer, A., Ramon‐Krauel, M., Díaz‐Manera, J., Olivé, M., et al. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00268 · Cited by 10
Deletion of translin (Tsn) induces robust adiposity and hepatic steatosis without impairing glucose tolerance
Shah, A. P., Johnson, M. D., Fu, X., Boersma, G. J., Shah, M. P., Wolfgang, M. J., Tamashiro, K. L., & Baraban, J. M. (2019) · International Journal of Obesity · doi:10.1038/s41366-018-0315-7 · Cited by 9
Normal Adipose Tissue Biology: Adipocytokines and Inflammation
Kim, J., & Bajaj, M. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-386456-7.02006-2 · Cited by 9
Clinical Implication of Adiponectin
Lim, S. K., & Jang, H. C. (2008) · Korean Diabetes Journal · doi:10.4093/kdj.2008.32.2.85 · Cited by 8
Lymphotoxin-α is a novel adiponectin expression suppressor following myocardial ischemia/reperfusion
Lau, W. B., Zhang, Y., Zhao, J., Liu, B., Wang, X., Yuan, Y., Christopher, T. A., Lopez, B., Gao, E., Koch, W. J., et al. (2013) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00012.2013 · Cited by 8
RETRACTED ARTICLE: Serum Zinc and Adiponectin Levels in Patients with Polycystic Ovary Syndrome, Adjusted for Anthropometric, Biochemical, Dietary Intake, and Physical Activity Measures
Mazloomi, S., Alizadeh, N., Aminzare, M., Niroomand, S., & Mousavi, S. N. (2017) · Biological Trace Element Research · doi:10.1007/s12011-017-0951-0 · Cited by 8
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Sadashiv, Tiwari, S., Paul, B. N., Kumar, S., Chandra, A., Dhananjai, S., & Negi, M. P. S. (2013) · HORMONES · doi:10.1007/bf03401293 · Cited by 8
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Zhang, Z., Wang, W., Jin, L., Cao, X., Jian, G., Wu, N., Xu, X., Yao, Y., & Wang, D. (2017) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2017/3275096 · Cited by 8
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Huang, S., Xu, Y., Peng, W., Cheng, J., Li, H., Shen, L., & Xia, L. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27743 · Cited by 8
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Koziołek, M., Krzyżanowska‐Świniarska, B., Mączyńska, I., Miazgowski, T., & Giedrys‐Kalemba, S. (2008) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-007-0446-6 · Cited by 8
From obesity to cardiovascular disease: pathological basis and clinical implications
Nardin, M., Mehran, R., Oliva, A., Kedhi, E., Galasso, G., Nardin, S., Savonitto, S., Condorelli, G., & Luca, G. D. (2026) · The American Journal of Medicine · doi:10.1016/j.amjmed.2026.04.041 · Cited by 7
Comparison of Adiponectin Levels in Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder, Obesity, Constitutional Thinness, and Healthy Controls: A Network Meta-Analysis
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Wiciński, M., Ozorowski, M., Wódkiewicz, E., Otto, S. W., Kubiak, K., & Malinowski, B. (2021) · Current Issues in Molecular Biology · doi:10.3390/cimb43030114 · Cited by 7
Adipose and Skeletal Muscle Expression of Adiponectin and Liver Receptor Homolog-1 With Weight Loss and Aerobic Exercise
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Hoareau, L., & Roche, R. (2010) · Drug Discovery Today Disease Mechanisms · doi:10.1016/j.ddmec.2011.01.002 · Cited by 8
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Satyanarayana, D. P., Roy, M., Parmar, C., Vadithya, M., ravuri, D. S., Manaswi, C., & Dravid, P. S. (2014) · IOSR Journal of Dental and Medical Sciences · doi:10.9790/0853-13561720 · Cited by 7
Higher plasma leptin largely explains increased C‐reactive protein levels in women
Dullaart, R. P. F., Vries, R. D., Dikkeschei, L. D., & Sluiter, W. J. (2007) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2007.01775.x · Cited by 7
Diet and Exercise in the Treatment of Fatty Liver
Magkos, F., Lavoie, J.-M., Kantartzis, K., & Gastaldelli, A. (2011) · Journal of Nutrition and Metabolism · doi:10.1155/2012/257671 · Cited by 7
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Hazelwood, E., Goudswaard, L. J., Lee, M. A., Vabistsevits, M., Pournaras, D. J., Brenner, H., Buchanan, D. D., Gruber, S. B., Gsur, A., Li, L., et al. (2025) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djaf201 · Cited by 7
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Schendel, S. A. (2017) · Aesthetic Surgery Journal · doi:10.1093/asj/sjx059 · Cited by 6
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Wakshlag, J. J., Streeter, R. M., Struble, A. M., Mann, S., Bauer, J. E., Nydam, D. V., Todhunter, R. J., Castelhano, M. G., & Cummings, B. P. (2015) · Veterinary Medicine Research and Reports · doi:10.2147/vmrr.s60478 · Cited by 6
Obesity and Immunity
Guest, C. B., Gao, Y., O’Connor, J. C., & Freund, G. G. (2007) · Elsevier eBooks · doi:10.1016/b978-012088576-3/50054-x · Cited by 6
Metabolic risk factors in formerly obese women – effects of a pronounced weight loss by gastric band operation compared with weight loss by diet alone
Ritt, M., Piza, H., Rhomberg, M., Aigner, F., & Lechleitner, M. (2005) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2004.00415.x · Cited by 6
Effects of lifestyle and genetic factors on the levels of serum adiponectin, a novel marker of the metabolic syndrome, in Finnish servicemen
Mousavinasab, F. (2007) · Cited by 6
Mangiferin mitigates dexamethasone-induced insulin resistance in rats: insight into vascular dysfunction and hepatic steatosis
Alsaedi, A. Q., Nader, M. A., El-Kashef, D. H., & Abdelmageed, M. E. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1572758 · Cited by 5
Irradiated obese adipocytes are prone to oxidative stress, inflammation, senescence, and fibrosis
Takkar, S., Kosmacek, E. A., McDowell, J. A., Liermann-Wooldrik, K. T., Chatterjee, A., & Oberley‐Deegan, R. E. (2025) · Scientific Reports · doi:10.1038/s41598-025-23533-7 · Cited by 6
Clinical Nutrition University: Muscle physiology and bioenergetics
Barazzoni, R. (2011) · e-SPEN the European e-Journal of Clinical Nutrition and Metabolism · doi:10.1016/j.eclnm.2011.02.002 · Cited by 5
Increased epicardial adipose tissue thickness associated with increased metabolic risk and the presence of heart failure in patients with Chronic Chagas disease
Peverengo, L. M., Castro, M. G., Zamora, M. A. G., Savarino, R., Peverengo, L. M., Prochetto, E., Marcipar, I. S., Arias, P., & Vicco, M. H. (2020) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1093/trstmh/traa189 · Cited by 6
The connections of sialic acids and diabetes mellitus: therapeutic or diagnostic value?
Ibrahim, M. A., Isah, M. B., Inim, M. D., Abdullahi, A. D., & Adamu, A. (2024) · Glycobiology · doi:10.1093/glycob/cwae053 · Cited by 5
Loss of Lkb1 in CD11c+ myeloid cells protects mice from diet-induced obesity while enhancing glucose intolerance and IL-17/IFN-γ imbalance
Sun, Y., Wang, B., Hu, Q., Zhang, H., Lai, X., Wang, T., Zhao, C., Wang, J., Zhang, X., Niu, Q., et al. (2023) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-023-04707-w · Cited by 5
[Adiponectin, insulin and glucose concentrations in overweight and obese subjects after a complex carbohydrates (fiber) diet].
Rodríguez, D. C. G., Liseti Solano, R., & Martínez, J. C. G. (2009) · PubMed · Cited by 5
Differential regulation of TNF receptor 1 and receptor 2 in adiponectin expression following myocardial ischemia
Wang, Y., Zhao, J., Zhang, Y., Lau, W. B., Jiao, L., Liu, B., Yuan, Y., Wang, X., Tao, L., Gao, E., et al. (2013) · International Journal of Cardiology · doi:10.1016/j.ijcard.2013.01.222 · Cited by 5
Relationship between adiponectin receptor 1 gene polymorphisms and ischemic stroke.
Han, Q., Shu, Z., Liang, X., Mi, R., Yang, L., & Li, P. (2015) · PubMed · Cited by 5
Leptin Levels and Insulin Dependence in Latent Autoimmune Diabetes in Adults
Delitala, A., Sanciu, F., Errigo, A., Delitala, G., & Pes, G. M. (2017) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2017.0059 · Cited by 5
Exploration of the Relationship between Adipocytokines, Tradition Risk Markers, Nontraditional Risk Markers and Anthropometric Measurements in T2DM Patients
Al‐Sowayan, N. S. (2015) · Journal of Biomedical Science and Engineering · doi:10.4236/jbise.2015.83018 · Cited by 5
Adiponectin levels may help assess the clinical repercussions of obesity irrespective of body mass index
Dermitzaki, E., Avgoustinaki, P. D., Spyridaki, E. C., Simos, P. G., Malliaraki, N. E., Venihaki, M., Tsatsanis, C., & Margioris, A. N. (2017) · HORMONES · doi:10.1007/bf03401521 · Cited by 5
Modulation of the somatotropic axis, adiponectin and cytokine secretion during highly pathogenic porcine reproductive and respiratory syndrome virus type 1 (HP-PRRSV-1) infection
Saleri, R., Cavalli, V., Ferrari, L., Ogno, G., Canelli, E., Martelli, P. R., & Borghetti, P. (2019) · Research in Veterinary Science · doi:10.1016/j.rvsc.2019.04.007 · Cited by 5
Glitazone loaded fat enhances adiponectin production and inhibits breast cancer cell proliferation
Shea, J., Terry, C. M., Edwards, K., & Agarwal, J. P. (2019) · Molecular Biology Reports · doi:10.1007/s11033-019-05094-x · Cited by 5
Effects of Piper sarmentosum on Metabolic Syndrome and Its Related Complications: A Review of Preclinical Evidence
Ekeuku, S. O., Azlina, M. F. N., & Chin, K. (2021) · Applied Sciences · doi:10.3390/app11219860 · Cited by 5
Angiopoietin-Like Protein 8/Leptin Crosstalk Influences Cardiac Mass in Youths With Cardiometabolic Risk: The BCAMS Study
Wang, D., Feng, D., Wang, Y., Dong, P., Wang, Y., Zhong, L., Li, B., Fu, J., Xiao, X., Speakman, J. R., et al. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.788549 · Cited by 5
Nonalcoholic Fatty Liver Disease
Cheung, O., & Sanyal, A. J. (2010) · Molecular pathology library · doi:10.1007/978-1-4419-7107-4_34 · Cited by 5
Plasma adiponectin and carotid intima–media thickness in non-obese patients with type 2 diabetes
Saif, A., Abdelhamid, A., Assem, M., & Mousa, S. (2015) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2015.05.013 · Cited by 5
ADIPONECTINA Y SUS EFECTOS PLEIOTRÓPICOS EN EL SISTEMA CARDIOVASCULAR. Revisión
Marcos, M. L., Francisco, J. R., Marín, A., & Romero-Vecchione, E. (2009) · Actualidad Contable FACES · Cited by 5
ЖИРНЫЙ ХВОСТ У ОВЕЦ: МЕТОДЫ ИЗУЧЕНИЯ ГЕНЕТИЧЕСКИХ МЕХАНИЗМОВ ФОРМИРОВАНИЯ ФЕНОТИПА И ИДЕНТИФИЦИРОВАННЫЕ ГЕНЫ-КАНДИДАТЫ (обзор)
Эрнста, Ф. Ф. Ж. —. В. И. А. Л. К., & ДЕНИСКОВА, Т. Е. (2019) · Sel skokhozyaistvennaya Biologiya · doi:10.15389/agrobiology.2019.6.1065rus · Cited by 4
Adipose Tissue-Derived Mediators in Multiple Myeloma: Linking Obesity to Bone Disease via Inflammatory Pathways
Stroe-Ionescu, A.-Ş., Tănase, A., Rotaru, I., Goanta, J. G., Pătraşcu, A. M., Boldeanu, M. V., Assani, M.-Z., Siloşi, I., Boldeanu, L., & Maria, D. T. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26125618 · Cited by 4
Serum Myostatin Levels are Elevated in Overweight Patients
Zhu, H. J., Yang, H. B., Wang, X. Q., Pan, H., Zhang, D. X., Li, N. S., Wang, L. J., & Gong, F. (2014) · The Open Obesity Journal · doi:10.2174/1876823701406010031 · Cited by 4
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Acquah, S., Eghan, B., & Boampong, J. N. (2016) · Biomedical Journal · doi:10.1016/j.bj.2016.09.003 · Cited by 4
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Rose, B. D., Rimm, E. B., Zhang, X., Sun, Q., Huang, T., Young, R. L., & Ivey, K. L. (2023) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2023.04.015 · Cited by 4
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DeBari, M. K., Johnston, E. K., Scott, J. V., Ilzuka, E., Sun, W., Webster‐Wood, V. A., & Abbott, R. D. (2024) · Cells · doi:10.3390/cells13151240 · Cited by 6
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Park, B.-M., Yoon, O.-J., & Lee, D.-H. (2017) · Korean Journal of Clinical Laboratory Science · doi:10.15324/kjcls.2017.49.1.28 · Cited by 4
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Authors: Kern, P. A., Di Gregorio, G. B., Lu, T., Rassouli, N., & Ranganathan, G.
Affiliations: Central Arkansas Veterans Healthcare System (US)
Central Arkansas Veterans Healthcare System and the Department of Medicine, Division of Endocrinology, University of Arkansas for Medical Sciences, Little Rock, Arkansas
ORCID: Kern, Philip A.
Venue: Diabetes
Publisher: American Diabetes Association
Published: 2003-07-01
Volume: 52
Issue: 7
Pages: 1779-1785
ISSN: 0012-1797 (ISSN-L)
1939-327X
DOI: 10.2337/diabetes.52.7.1779
OpenAlex: W2470404765
Cited by: 875
References: 48
Citations by year: 2026: 9 · 2025: 13 · 2024: 13 · 2023: 23 · 2022: 26 · 2021: 25 · 2020: 34 · 2019: 33 · 2018: 37 · 2017: 37 · 2016: 37 · 2015: 36 · 2014: 48 · 2013: 47 · 2012: 52
FWCI: 35.75
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Diabetes (publishedVersion)
PubMed (publishedVersion)
UKnowledge (University of Kentucky) (submittedVersion)
Funders: University of Arkansas
University of Arkansas for Medical Sciences
National Institutes of Health
School of Medicine, Indiana University
National Institute of Diabetes and Digestive and Kidney Diseases (DK 39176)
National Center for Research Resources (M01RR014288)
NIH Clinical Center
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
Keywords: adiponectin, adipose tissue, obesity, insulin resistance, sex differences, insulin sensitivity index, TNF-α, plasma adiponectin, leptin, interleukin-6
MeSH terms: Adipose Tissue, Female, Humans, Insulin Resistance, Male, Obesity, Proteins, Reference Values, RNA, Messenger, Sex Characteristics, Tumor Necrosis Factor-alpha, Body Mass Index, Intercellular Signaling Peptides and Proteins, Adiponectin

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