SGK1 Kinase Upregulates GLUT1 Activity and Plasma Membrane Expression

Mechanism of activation of protein kinase B by insulin and IGF‐1.

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Protein Kinase SGK Mediates Survival Signals by Phosphorylating the Forkhead Transcription Factor FKHRL1 (FOXO3a)

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Phosphorylation of Nedd4‐2 by Sgk1 regulates epithelial Na+ channel cell surface expression

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Serum and glucocorticoid‐inducible kinase (SGK) is a target of the PI 3‐kinase‐stimulated signaling pathway

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Characterization of <i>sgk</i>, a Novel Member of the Serine/Threonine Protein Kinase Gene Family Which Is Transcriptionally Induced by Glucocorticoids and Serum

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Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

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Insulin regulation of glucose uptake: a complex interplay of intracellular signalling pathways

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Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase

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Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume

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Activation of GLUT1 by metabolic and osmotic stress: potential involvement of AMP-activated protein kinase (AMPK)

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Regulation and Physiological Roles of Serum- and Glucocorticoid-Induced Protein Kinase Isoforms

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Stimulus-Dependent Regulation of Serum and Glucocorticoid Inducible Protein Kinase (SGK) Transcription, Subcellular Localization and Enzymatic Activity

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Cell Volume in the Regulation of Cell Proliferation and Apoptotic Cell Death

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The Use of Xenopus laevis Oocytes for the Functional Characterization of Heterologously Expressed Membrane Proteins

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Facilitated glucose transporter protein type 1 (GLUT1) deficiency syndrome: impaired glucose transport into brain – a review

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Regulation of Glucose Transporter SGLT1 by Ubiquitin Ligase Nedd4‐2 and Kinases SGK1, SGK3, and PKB

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Standard Isolation of Primary Adipose Cells from Mouse Epididymal Fat Pads Induces Inflammatory Mediators and Down-regulates Adipocyte Genes

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Hyperosmotic Stress Stimulates Promoter Activity and Regulates Cellular Utilization of the Serum- and Glucocorticoid-inducible Protein Kinase (Sgk) by a p38 MAPK-dependent Pathway*

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Opposite Translational Control of GLUT1 and GLUT4 Glucose Transporter mRNAs in Response to Insulin

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Insulin-stimulated GLUT4 Translocation Is Mediated by a Divergent Intracellular Signaling Pathway

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Requirement for Phosphoinositide 3-Kinase in Insulin-Stimulated GLUT4 Translocation in 3T3-L1 Adipocytes

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Activation of Serum- and Glucocorticoid-induced Protein Kinase (Sgk) by Cyclic AMP and Insulin

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Regulation of Channels by the Serum and Glucocorticoid-Inducible Kinase - Implications for Transport, Excitability and Cell Proliferation

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Cell Cycle and Hormonal Control of Nuclear-Cytoplasmic Localization of the Serum- and Glucocorticoid-inducible Protein Kinase, Sgk, in Mammary Tumor Cells

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Protein Kinase B Stimulates the Translocation of GLUT4 but Not GLUT1 or Transferrin Receptors in 3T3-L1 Adipocytes by a Pathway Involving SNAP-23, Synaptobrevin-2, and/or Cellubrevin

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Dehydroepiandrosterone Stimulates Glucose Uptake in Human and Murine Adipocytes by Inducing GLUT1 and GLUT4 Translocation to the Plasma Membrane

Perrini, S., Natalicchio, A., Laviola, L., Belsanti, G., Montrone, C., Cignarelli, A., Minielli, V., Grano, M., Pergola, G. D., GIORGINO, R., et al. (2004) · Diabetes · doi:10.2337/diabetes.53.1.41 · Cited by 115 · see citing works

Regulation of the glutamate transporter EAAT1 by the ubiquitin ligase Nedd4‐2 and the serum and glucocorticoid‐inducible kinase isoforms SGK1/3 and protein kinase B

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Enrichment enhances the expression of sgk, a glucocorticoid‐induced gene, and facilitates spatial learning through glutamate AMPA receptor mediation

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Analysis of insulin signalling by RNAi-based gene silencing

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Stimulation of Xenopus oocyte Na+,K+ATPase by the serum and glucocorticoid-dependent kinase sgk1

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SGK1 increases Na,K-ATP cell-surface expression and function in Xenopus laevis oocytes

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Properties and regulation of glutamine transporter SN1 by protein kinases SGK and PKB

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Alteration of serum/glucocorticoid regulated kinase-1 (sgk-1) gene expression in rat hippocampus after transient global ischemia

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Regulation of intestinal phosphate cotransporter NaPi IIb by ubiquitin ligase Nedd4–2 and by serum- and glucocorticoid-dependent kinase 1

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Retinal Colocalization and In Vitro Interaction of the Glutamate Receptor EAAT3 and the Serum- and Glucocorticoid-Inducible Kinase SGK1

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Stimulation of the EAAT4 glutamate transporter by SGK protein kinase isoforms and PKB

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Regulation and Physiological Roles of Serum- and Glucocorticoid-Induced Protein Kinase Isoforms

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Stimulation of renal Na+ dicarboxylate cotransporter 1 by Na+/H+ exchanger regulating factor 2, serum and glucocorticoid inducible kinase isoforms, and protein kinase B

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Ectopic Expression of Protein Kinase CβII, -δ, and -ϵ, but Not -βI or -ζ, Provide for Insulin Stimulation of Glucose Uptake in NIH-3T3 Cells

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Prolonged glucose infusion into conscious rats inhibits early steps in insulin signalling and induces translocation of GLUT4 and protein kinase C in skeletal muscle

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Fractionation of endocytic vesicles and glucose-transporter-containing vesicles in rat adipocytes

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Different mammalian facilitative glucose transporters expressed in Xenopus oocytes.

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(Patho)physiological Significance of the Serum- and Glucocorticoid-Inducible Kinase Isoforms

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Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release

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GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer

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Reversal of tumor immune inhibition using a chimeric cytokine receptor.

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Significance of SGK1 in the regulation of neuronal function

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Distinct Akt phosphorylation states are required for insulin regulated Glut4 and Glut1-mediated glucose uptake

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Akt Mediates the Effect of Insulin on Epithelial Sodium Channels by Inhibiting Nedd4-2*

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The physiological impact of the serum and glucocorticoid-inducible kinase SGK1

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Pathomechanisms of Type 2 Diabetes Genes

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Targeting SGK1 in diabetes

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Periodontitis and Insulin Resistance: Casual or Causal Relationship?

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Mitochondrial Perturbations Couple mTORC2 to Autophagy in C. elegans

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Controlling cell growth and survival through regulated nutrient transporter expression

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Glucocorticoid receptor signaling in astrocytes is required for aversive memory formation

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Resistance of mice lacking the serum- and glucocorticoid-inducible kinase SGK1 against salt-sensitive hypertension induced by a high-fat diet

Huang, D. Y., Boini, K. M., Oßwald, H., Friedrich, B., Artunç, F., Ullrich, S., Rajamanickam, J., Palmada, M., Wulff, P., Kuhl, D., et al. (2006) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00299.2005 · Cited by 71 · see citing works

SGK1 signaling promotes glucose metabolism and survival in extracellular matrix detached cells

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Association of SGK1 Gene Polymorphisms with Type 2 Diabetes

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Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity

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Renal glucose transporters: novel targets for hyperglycemia management

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Differential Regulation of Serum- and Glucocorticoid-Inducible Kinase 1 (SGK1) Splice Variants Based on Alternative Initiation of Transcription

Simon, P. D., Schneck, M., Hochstetter, T., Koutsouki, E., Mittelbronn, M. G. A., Merseburger, A. S., Weigert, C., Niess, A. M., & Lang, F. J. W. (2007) · Cellular Physiology and Biochemistry · doi:10.1159/000110432 · Cited by 51 · see citing works

DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders

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Role of SGK1 kinase in regulating glucose transport via glucose transporter GLUT4

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Activation of serum/glucocorticoid-induced kinase 1 (SGK1) underlies increased glycogen levels, mTOR activation, and autophagy defects in Lafora disease

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Serum- and Glucocorticoid-Inducible Kinase 1 Mediates Salt Sensitivity of Glucose Tolerance

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Initiatives to Promote Effective Self-Care Skills in Children and Adolescents with Diabetes Mellitus

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Restoring glucose uptake rescues neutrophil dysfunction and protects against systemic fungal infection in mouse models of kidney disease

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Nox-generated ROS modulate glucose uptake in a leukaemic cell line

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SGK1-sensitive renal tubular glucose reabsorption in diabetes

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Basic fibroblast growth factor regulates glucose metabolism through glucose transporter 1 induced by hypoxia-inducible factor-1α in adipocytes

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Impaired Mast Cell Activation in Gene-Targeted Mice Lacking the Serum- and Glucocorticoid-Inducible Kinase SGK1

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Serum glucocorticoid inducible kinase (SGK)-1 protects endothelial cells against oxidative stress and apoptosis induced by hyperglycaemia Francesca FerrelliDonatella PastoreBarbara CapuaniMarco F. LombardoMarcel Blot-Chabaud • Andrea CoppolaKatia BaselloAngelica GalliGiulia DonadelMaria RomanoSara Caratelli • Francesca PacificiRoberto ArrigaNicola Di DanielePaolo SbracciaGiuseppe Sconocchia • Alfonso BelliaManfredi TesauroMassimo FedericiDavid Della-MorteDavide Lauro

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