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Cited by 1,084

The DOI matches its Crossref record; 185 of the 185 references it cites were found in a registry or an index.

Diabetes-Related Microvascular and Macrovascular Diseases in the Physical Therapy Setting

Open access
Cade, W Todd·2008·Physical Therapy

Abstract

Physical therapists commonly treat people with diabetes for a wide variety of diabetes-associated impairments, including those from diabetes-related vascular disease. Diabetes is associated with both microvascular and macrovascular diseases affecting several organs, including muscle, skin, heart, brain, and kidneys. A common etiology links the different types of diabetes-associated vascular disease. Common risk factors for vascular disease in people with diabetes, specifically type 2 diabetes, include hyperglycemia, insulin resistance, dyslipidemia, hypertension, tobacco use, and obesity. Mechanisms for vascular disease in diabetes include the pathologic effects of advanced glycation end product accumulation, impaired vasodilatory response attributable to nitric oxide inhibition, smooth muscle cell dysfunction, overproduction of endothelial growth factors, chronic inflammation, hemodynamic dysregulation, impaired fibrinolytic ability, and enhanced platelet aggregation. It is becoming increasingly important for physical therapists to be aware of diabetes-related vascular complications as more patients present with insulin resistance and diabetes. The opportunities for effective physical therapy interventions (such as exercise) are significant.

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Metadata

Authors
Cade, W. T.
Venue
Physical Therapy
Published
2008-11-01
Volume
88
Issue
11
Pages
1322-1335
ISSN
  • 0031-9023 (ISSN-L)
  • 1538-6724
OpenAlex
W2155905771
Cited by
1,084
References
185
FWCI
4.79
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Diabetes-Related Microvascular and Macrovascular Diseases in the Physical Therapy Setting. https://app.cochat.ai/papers/10.2522/ptj.20080008
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Cade, W. T. (2008). Diabetes-Related Microvascular and Macrovascular Diseases in the Physical Therapy Setting. Physical Therapy. https://doi.org/10.2522/ptj.20080008

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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