The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
KSRP, many functions for a single protein
Abstract
KSRP is a single-strand nucleic acids binding protein that affects RNA fate at multiple levels. KSRP modular structure and its complex pattern of post-translational modifications underpin the interaction with a wide spectrum of RNA target sequences, as well as with other RNA-binding proteins and molecular adaptors. These interactions are important to the regulation of different steps of mRNA metabolism and, in turn, modulate several aspects of cellular proliferation and differentiation. In this review we will discuss in detail KSRP ability to i) promote decay of labile mRNAs interacting with some components of the mRNA decay machinery and ii) favor the maturation of a select group of microRNA precursors.
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“Some ARE-BPs are decay-promoting factors, such as KH-type splicing regulatory proteins (KSRPs), that interact with AREs and recruit RNA degradation machinery to the mRNA.”
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2 retracted
Fukuda, T., Yamagata, K., Fujiyama, S., Matsumoto, T., Koshida, I., Yoshimura, K., Mihara, M., Naitou, M., Endoh, H., Nakamura, T., et al. (2007) · Nature Cell Biology · doi:10.1038/ncb1577 · Cited by 428
RetractedA TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function
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RetractedMicroRNA expression profiles classify human cancers
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(2008) · doi:10.1038/nrg2290 · Cited by 5,199
Many roads to maturity: microRNA biogenesis pathways and their regulation
Winter, J., Jung, S., Keller, S., Gregory, R. I., & Diederichs, S. (2009) · Nature Cell Biology · doi:10.1038/ncb0309-228 · Cited by 2,656
Impaired microRNA processing enhances cellular transformation and tumorigenesis
Kumar, M. S., Lu, J., Mercer, K. L., Golub, T. R., & Jacks, T. (2007) · Nature Genetics · doi:10.1038/ng2003 · Cited by 1,463
Selective Blockade of MicroRNA Processing by Lin28
Viswanathan, S. R., Daley, G. Q., & Gregory, R. I. (2008) · Science · doi:10.1126/science.1154040 · Cited by 1,437
The highways and byways of mRNA decay
Garneau, N. L., Wilusz, J., & Wilusz, C. J. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2104 · Cited by 1,294
The Many Pathways of RNA Degradation
Houseley, J., & Tollervey, D. (2009) · Cell · doi:10.1016/j.cell.2009.01.019 · Cited by 1,229
Extensive post-transcriptional regulation of microRNAs and its implications for cancer
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Research works printed but not linked: 2
- R. Gherzi, M. Trabucchi, M. Ponassi, T. Ruggiero, G. Corte, C. Moroni, C.-Y. Chen, K.S. Khabar, J.S. Andersen, and Briata P: The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K- AKT signaling. PLoS Biol. 5, e5 (2006)
- M. Nechama, Y. Peng, O. Bell, P. Briata, R. Gherzi, D.R. Schoenberg, and T. Naveh-Many: KSRP-PMR1- exosome association determines parathyroid hormone mRNA levels and stability in transfected cells. BMC Cell Biol. 10, 70 (2009)
Cited by
Li, Y., Dalli, J., Chiang, N., Baron, R. M., Quintana, C., & Serhan, C. N. (2013) · Immunity · doi:10.1016/j.immuni.2013.10.011 · Cited by 126
Singh, A. B., Kan, C. F. K., Shende, V., Dong, B., & Liu, J. (2014) · Journal of Lipid Research · doi:10.1194/jlr.m049429 · Cited by 35
Singh, A. B., Li, H., Kan, C. F. K., Dong, B., Nicolls, M. R., & Liu, J. (2014) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.112.301131 · Cited by 32
Metadata
- Authors
- Briata, P.
- Venue
- Frontiers in Bioscience
- Publisher
- IMR Press
- Published
- 2011
- Volume
- 16
- Issue
- 1
- Pages
- 1787
- ISSN
- 1093-9946
- 1093-4715
- DOI
- 10.2741/3821
- Cited by
- 49
- References
- 55
- Language
- en
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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