Psychiatric Findings in Suspected and Confirmed Middle East Respiratory Syndrome Patients Quarantined in Hospital: A Retrospective Chart Analysis
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OBJECTIVE: Little is known about the psychiatric complications or risk factors for depression in suspected or confirmed Middle East Respiratory Syndrome (MERS) patients quarantined in hospital. METHODS: A retrospective chart review was performed of all the patients admitted to the acute MERS inpatient unit at the NMC during the 2015 outbreak. RESULTS: 30 (75%) were confirmed to be MERS-CoV positive among 40 admitted cases. Among the 24 MERS survivors, 17 (70.8%) exhibited psychiatric symptoms and 10 (41.7%) received a psychiatric diagnosis and medication during their hospital stay. Suspected MERS patients did not exhibit psychiatric symptoms or receive a psychiatric diagnosis. 27 suspected or confirmed MERS patients (age 41.15±18.64, male 37.0%) completed psychological assessments. A multiple linear regression analysis revealed that the Korean National Health and Nutrition Examination Survey-Short form and the Impact of Event Scale-Revised scores were significantly positively correlated with Patient Health Questionnaire-9 scores. CONCLUSION: Our findings indicate that the acute treatment of MERS-CoV infections in quarantine had a significant impact on the patients' mental health. Furthermore, assessment of the risk factors for depression may identify vulnerable patients who require psychiatric care and attention during hospital quarantine.
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COVID-19 related psychiatric symptoms have been largely described during and after the occurrence of other respiratory pandemics, such as MERS and SARS.
“Moreover, COVID-19 related psychiatric symptoms (including anger, anxiety, suicidal ideas, hallucinations, insomnia, impaired memory, poor concentration, time disorientation, fear/panic, pressured speech, mood alterations, pessimistic thinking, crying spell and persecutory ideas) have been largely described during and after the occurrence of other respiratory pandemics, such as MERS [151] and SARS”
From Hyperactivation of P2X7 receptors as a culprit of COVID-19 neuropathology (2021) · cites this paper as [151]
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- Authors
- Kim, H.-C., Yoo, S.-Y., Lee, B.-H., Lee, S. H., & Shin, H.-S.
- Affiliations
- National Medical Center (KR)
- Corresponding author
- Lee, So Hee
- Shin, Hyoung-Shik
- Venue
- Psychiatry Investigation
- Publisher
- Korean Neuropsychiatric Association
- Published
- 2018-04-25
- Volume
- 15
- Issue
- 4
- Pages
- 355-360
- ISSN
- 1738-3684 (ISSN-L)
- 1976-3026
- PMC
- PMC5912494
- OpenAlex
- W2795049241
- Cited by
- 146
- References
- 10
- Citations by year
- 2025: 3 · 2024: 1 · 2023: 20 · 2022: 32 · 2021: 43 · 2020: 45 · 2019: 2
- FWCI
- 26.44
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- Locations
- Psychiatry Investigation (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Funders
- Korea Health Industry Development Institute
- Ministry of Health and Welfare (HI15C3227)
- Topics
- Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
- Health Sciences › Medicine › Neurology › Long-Term Effects of COVID-19
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Keywords
- MERS, MERS-CoV, depression, psychiatric symptoms, mental health, risk factors for depression, psychological distress, Impact of Event Scale-Revised, Korea National Health and Nutrition Examination Survey, PHQ-9
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