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Application of PBPK modelling in drug discovery and development at Pfizer
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“The prediction accuracy of PBPK models were assessed according to the fold-error between the observed value and the predicted value, which was also widely accepted [48,49].”
From Predicting Food–Drug Interactions between Piperine and CYP3A4 Substrate Drugs Using PBPK Modeling (2024) · cites this paper as [49]
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Cited by
Jones, H., Chen, Y., Gibson, C., Heimbach, T., Parrott, N., Peters, S., Snoeys, J., Upreti, V., Zheng, M., & Hall, S. (2015) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.37 · Cited by 488
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Predicting Pharmacokinetic Profiles Using in Silico Derived Parameters
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Metadata
- Authors
- Jones, H. M., Dickins, M., Youdim, K., Gosset, J. R., Attkins, N. J., Hay, T. L., Gurrell, I. K., Logan, Y. R., Bungay, P. J., Jones, B. C., & Gardner, I. B.
- Venue
- Xenobiotica
- Publisher
- Informa UK Limited
- Published
- 2011-10-30
- Volume
- 42
- Issue
- 1
- Pages
- 94-106
- ISSN
- 0049-8254
- 1366-5928
- Cited by
- 92
- References
- 12
- Language
- en
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- Jones, H. M., Dickins, M., Youdim, K., Gosset, J. R., Attkins, N. J., Hay, T. L., Gurrell, I. K., Logan, Y. R., Bungay, P. J., Jones, B. C., & Gardner, I. B. (2012). Application of PBPK modelling in drug discovery and development at Pfizer. Xenobiotica. https://doi.org/10.3109/00498254.2011.627477
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