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Development of New Cell Lines for Animal Cell Biotechnology

Macdonald, Caroline·1990·Critical Reviews in Biotechnology

Abstract

Mammalian cell culture has been an important technique in laboratory-scale experimentation for many decades. Developments in large-scale culture have been due to the need to grow large numbers of cells to support the growth of viruses for vaccine production, and more recently, for growing hybridoma cells as a source of monoclonal antibody. Increasingly, however, pharmaceutical products such as hormones, enzymes, growth factors, and clotting factors are being produced from cell lines which have been manipulated by recombinant DNA techniques. It is clear, therefore, that the high cost of growing mammalian cells on a large scale does not necessarily prohibit their use for biotechnology, and indeed there is considerable evidence to suggest that animal cell biotechnology will continue to be a major growth area in the future.

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Metadata

Authors
Macdonald, C.
Affiliations
Department of Bioscience and Biotechnology, University of Strathclyde, Glasgow, UK
Venue
Critical Reviews in Biotechnology
Published
1990-01
Volume
10
Issue
2
Pages
155-178
ISSN
  • 0738-8551
  • 1549-7801
Cited by
25
References
1
Language
en

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CoChat. (2026). Citation check: Development of New Cell Lines for Animal Cell Biotechnology. https://app.cochat.ai/papers/10.3109/07388559009068265
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Macdonald, C. (1990). Development of New Cell Lines for Animal Cell Biotechnology. Critical Reviews in Biotechnology. https://doi.org/10.3109/07388559009068265