Epidemiological and Laboratory Evidence of PCB-lnduced Neurotoxicity
Abstract
The purpose of this review is to provide a selective, but critical, assessment of important findings derived from both epidemiological and laboratory studies suggesting that: (1) exposure to polychlorinated biphenyls (PCBs) and related halogenated aromatic hydrocarbons induces significant neurological and behavioral dysfunctions in humans and laboratory animals, particularly following exposure during gestation and lactation; (2) the neurochemical actions of PCBs depend on their structure and the developmental status of the animal at the time of exposure; and (3) the mechanisms responsible for these changes may involve alterations in basic cellular signaling processes and endocrine function that influence the synthesis and activity of important central nervous system neurotransmitters, the organization of the developing brain, and the behavioral responses to these environmental contaminants.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The weight of evidence from epidemiological studies supports a negative association between developmental exposure to PCBs and neuropsychological function in infancy and childhood.
“The weight of evidence from epidemiological studies supports a negative association between developmental exposure to PCBs and neuropsychological function in infancy and childhood [ 56 , 95–99 ].”
From DNA methylation: a mechanism linking environmental chemical exposures to risk of autism spectrum disorders? (2016) · cites this paper as [95]
Cites
Circuitry of Primate Prefrontal Cortex and Regulation of Behavior by Representational Memory
Goldman‐Rakic, P. S. (1987) · Comprehensive Physiology · doi:10.1002/cphy.cp010509 · Cited by 1,960 · see citing works
Safe, S. (1990) · Critical Reviews in Toxicology · doi:10.3109/10408449009089873 · Cited by 1,871 · see citing works
Safe, S. H. (1994) · Critical Reviews in Toxicology · doi:10.3109/10408449409049308 · Cited by 1,760 · see citing works
Cognitive Deficit Caused by Regional Depletion of Dopamine in Prefrontal Cortex of Rhesus Monkey
Brozoski, T. J., Brown, R. M., Rosvold, H. E., & Goldman, P. S. (1979) · Science · doi:10.1126/science.112679 · Cited by 1,500 · see citing works
Erickson, M. D. (1986) · Medical Entomology and Zoology · Cited by 810 · see citing works
Electrophysiology of Cognitive Processing
Hillyard, S. A., & Marta Kutas, A. (1983) · Annual Review of Psychology · doi:10.1146/annurev.ps.34.020183.000341 · Cited by 767 · see citing works
Sawaguchi, T., & Goldman‐Rakic, P. S. (1994) · Journal of Neurophysiology · doi:10.1152/jn.1994.71.2.515 · Cited by 649 · see citing works
Diamond, A., & Goldman-Rakic, P. S. (1989) · Experimental Brain Research · doi:10.1007/bf00248277 · Cited by 628 · see citing works
Jacobson, J. L., Jacobson, S. W., & Humphrey, H. E. B. (1990) · The Journal of Pediatrics · doi:10.1016/s0022-3476(05)81642-7 · Cited by 601 · see citing works
Murphy, B. L., Arnsten, A. F., Goldman-Rakic, P. S., & Roth, R. H. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.3.1325 · Cited by 590 · see citing works
High-resolution PCB analysis: synthesis and chromatographic properties of all 209 PCB congeners
Mullins, M. D., Pochini, C. M., McCrindle, S., Romkes, M., Safe, S. H., & Safe, L. M. (1984) · Environmental Science & Technology · doi:10.1021/es00124a014 · Cited by 586 · see citing works
Congenital Poisoning by Polychlorinated Biphenyls and Their Contaminants in Taiwan
Rogan, W. J., Gladen, B. C., Hung, K., Koong, S.-L., Shih, L.-Y., Taylor, J. S., Wu, Y., Yang, D. C., Ragan, N. B., & Hsu, C. (1988) · Science · doi:10.1126/science.3133768 · Cited by 543 · see citing works
Chemoarchitecture of the Brain
Nieuwenhuys, R. (1985) · Springer eBooks · doi:10.1007/978-3-642-70426-0 · Cited by 500 · see citing works
Zigmond, R. E., Schwarzschild, M. A., & Rittenhouse, A. R. (1989) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.12.030189.002215 · Cited by 486 · see citing works
Koopman-Esseboom, C., Morse, D. C., Weisglas‐Kuperus, N., Lutke-Schipholt, I. J., van der Paauw, C. G., Tuinstra, L. G. M. T., Brouwer, A., & Sauer, P. J. J. (1994) · Pediatric Research · doi:10.1203/00006450-199410000-00009 · Cited by 468 · see citing works
Neonatal effects of transplacental exposure to PCBs and DDE
Rogan, W. J., Gladen, B. C., McKinney, J. D., Carreras, N., Hardy, P., Thullen, J. D., Tinglestad, J., & Tully, M. R. (1986) · The Journal of Pediatrics · doi:10.1016/s0022-3476(86)80397-3 · Cited by 443 · see citing works
The influence of fatigue on health-related quality of life in patients with Parkinson's disease
Herlofson, K., & Larsen, J. O. (2003) · Acta Neurologica Scandinavica · doi:10.1034/j.1600-0404.2003.02033.x · Cited by 441 · see citing works
Prenatal exposure to polychlorinated biphenyls: Effects on birth size and gestational age
Fein, G. G., Jacobson, J. L., Jacobson, S. W., Schwartz, P. M., & Dowler, J. K. (1984) · The Journal of Pediatrics · doi:10.1016/s0022-3476(84)80139-0 · Cited by 441 · see citing works
The Effect of Intrauterine PCB Exposure on Visual Recognition Memory
Jacobson, S. W., Fein, G. G., Jacobson, J. L., Schwartz, P. M., & Dowler, J. K. (1985) · Child Development · doi:10.2307/1130097 · Cited by 437 · see citing works
Korach, K. S., Sarver, P. J., Chae, K., McLachlan, J. A., & McKinney, J. D. (1988) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)13092-7 · Cited by 425 · see citing works
Environmental and dietary estrogens and human health: is there a problem?
Safe, S. (1995) · Environmental Health Perspectives · doi:10.1289/ehp.95103346 · Cited by 418 · see citing works
Chemoarchitecture of the brain
(1987) · Comparative Biochemistry and Physiology Part A Physiology · doi:10.1016/0300-9629(87)90305-7 · Cited by 416 · see citing works
Greene, L. A., & Rein, G. (1977) · Brain Research · doi:10.1016/0006-8993(77)90005-1 · Cited by 414 · see citing works
Microcontaminants and reproductive impairment of the Forster's tern on Green Bay, Lake Michigan-1983
Kubiak, T. J., Harris, H. J., Smith, L. M., Schwartz, T. R., Stalling, D. L., Trick, J., Sileo, L., Docherty, D. E., & Erdman, T. C. (1989) · Archives of Environmental Contamination and Toxicology · doi:10.1007/bf01225009 · Cited by 406 · see citing works
Effects of exposure to PCBs and related compounds on growth and activity in children
Jacobson, J. L., Jacobson, S. W., & Humphrey, H. E. B. (1990) · Neurotoxicology and Teratology · doi:10.1016/0892-0362(90)90050-m · Cited by 399 · see citing works
Goldman, P. S., Rosvold, H. E., Vest, B., & Galkin, T. W. (1971) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0031649 · Cited by 381 · see citing works
Kuratsune, M., Yoshimura, T., Matsuzaka, J., & Yamaguchi, A. (1972) · Environmental Health Perspectives · doi:10.1289/ehp.7201119 · Cited by 372 · see citing works
Bedard, D. L., Unterman, R., Bopp, L. H., Brennan, M. J., Haberl, M. L., & Johnson, C. (1986) · Applied and Environmental Microbiology · doi:10.1128/aem.51.4.761-768.1986 · Cited by 361 · see citing works
Gladen, B. C., Rogan, W. J., Hardy, P., Thullen, J. D., Tingelstad, J. B., & Tully, M. R. (1988) · The Journal of Pediatrics · doi:10.1016/s0022-3476(88)80569-9 · Cited by 343 · see citing works
Polychlorinated biphenyls as hormonally active structural analogues.
McKinney, J. D., & Waller, C. L. (1994) · Environmental Health Perspectives · doi:10.1289/ehp.94102290 · Cited by 309 · see citing works
Goldey, E. S., Kehn, L. S., Lau, C. S., Rehnberg, G. L., & Crofton, K. M. (1995) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1995.1210 · Cited by 289 · see citing works
Safe, S. H., Astroff, B., Harris, M. A., Zacharewski, T. R., Dickerson, R. L., Romkes, M., & Biegel, L. B. (1991) · Pharmacology & Toxicology · doi:10.1111/j.1600-0773.1991.tb01321.x · Cited by 287 · see citing works
Huisman, M., Koopman-Esseboom, C., Fidler, V., Hadders‐Algra, M., van der Paauw, C. G., Tuinstra, L. G. M. T., Weisglas‐Kuperus, N., Sauer, P. J. J., Touwen, B. C. L., & Boersma, E. R. (1995) · Early Human Development · doi:10.1016/0378-3782(94)01611-r · Cited by 283 · see citing works
Cognitive impairments associated with early Parkinson's disease
Levin, B. E., Llabre, M. M., & Weiner, W. J. (1989) · Neurology · doi:10.1212/wnl.39.4.557 · Cited by 278 · see citing works
Kish, S. J., Shannak, K. S., Rajput, A. H., Deck, J. H. N., & Hornykiewicz, O. (1992) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1992.tb09766.x · Cited by 272 · see citing works
Brouwer, A., Ahlborg, U. G., van den Berg, M., Birnbaum, L. S., Boersma, E. R., Bosveld, B. A. T. C., Denison, M. S., Gray, L. E., Hagmar, L., Holene, E., et al. (1995) · European Journal of Pharmacology Environmental Toxicology and Pharmacology · doi:10.1016/0926-6917(95)90015-2 · Cited by 267 · see citing works
Self-citationGladen, B. C., & Rogan, W. J. (1991) · The Journal of Pediatrics · doi:10.1016/s0022-3476(05)81039-x · Cited by 262 · see citing works
Cognitive Development of Yu-Cheng ('Oil Disease') Children Prenatally Exposed to Heat-Degraded PCBs
Chen, Y.-C. J. (1992) · JAMA · doi:10.1001/jama.1992.03490220057028 · Cited by 253 · see citing works
Neurotoxicity of polychlorinated biphenyls: Structure-activity relationship of individual congeners
Shain, W. G., Bush, B., & Seegal, R. F. (1991) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(91)90131-w · Cited by 246 · see citing works
Self-citationSpink, D. C., Eugster, H., Lincoln, D. W., Schuetz, J. D., Schuetz, E. G., Johnson, J. A., Kaminsky, L. S., & Gierthy, J. F. (1992) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(92)90404-k · Cited by 244 · see citing works
Morse, D. C., Klasson‐Wehler, E., Wesseling, W., Koeman, J. H., & Brouwer, A. (1996) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1996.0034 · Cited by 242 · see citing works
Developmental Neurotoxicity of PCBs in Humans: What Do We Know and Where Do We Go From Here?
Schantz, S. L. (1996) · Neurotoxicology and Teratology · doi:10.1016/s0892-0362(96)90001-x · Cited by 224 · see citing works
Infant recognition memory and later intelligence
Fagan, J. F., & McGrath, S. P. (1981) · Intelligence · doi:10.1016/0160-2896(81)90002-7 · Cited by 222 · see citing works
PCBs, DDE, and child development at 18 and 24 months
Rogan, W. J., & Gladen, B. C. (1991) · Annals of Epidemiology · doi:10.1016/1047-2797(91)90010-a · Cited by 220 · see citing works
Schantz, S. L. (1995) · Fundamental and Applied Toxicology · doi:10.1006/faat.1995.1081 · Cited by 214 · see citing works
Discovery and epidemiology of PCB poisoning in Taiwan: a four-year followup.
Hsu, S. T., I, C., Hsu, S. K., Wu, S. S., Hsu, N. H., Yeh, C. C., & Wu, S. (1985) · Environmental Health Perspectives · doi:10.1289/ehp.59-1568088 · Cited by 213 · see citing works
Event-related potentials of the brain and cognitive processes: Approaches and applications
Brandeis, D., & Lehmann, D. (1986) · Neuropsychologia · doi:10.1016/0028-3932(86)90049-7 · Cited by 208 · see citing works
Seegal, R. F. (1990) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(90)90113-9 · Cited by 207 · see citing works
Self-citationNESS, D. K., Schantz, S. L., Moshtaghian, J., & Hansen, L. G. (1993) · Toxicology Letters · doi:10.1016/0378-4274(93)90023-q · Cited by 201 · see citing works
Ahlborg, U. G., Brouwer, A., Fingerhut, M. A., Jacobson, J. L., Jacobson, S. W., Kennedy, S. W., Kettrup, A., Koeman, J. H., Poiger, H., Rappe, C., et al. (1992) · European Journal of Pharmacology Environmental Toxicology and Pharmacology · doi:10.1016/0926-6917(92)90029-c · Cited by 196 · see citing works
Self-citationMorse, D. C., Groen, D., Veerman, M., Vanamerongen, C. J., Koëter, H. B. W. M., Vanprooije, A. E. S., Visser, T. J., Koeman, J. H., & Brouwer, A. (1993) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1993.1168 · Cited by 195 · see citing works
(1987) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(87)90073-3 · Cited by 182 · see citing works
The metabolism of chlorobiphenyls — A review
Sundström, G., Hutzinger, O., & Safe, S. (1976) · Chemosphere · doi:10.1016/0045-6535(76)90002-3 · Cited by 179 · see citing works
Huisman, M., Koopman-Esseboom, C., Lanting, C. I., van der Paauw, C. G., Tuinstra, L. G. M. T., Fidler, V., Weisglas‐Kuperus, N., Sauer, P. J. J., Boersma, E. R., & Touwen, B. C. L. (1995) · Early Human Development · doi:10.1016/0378-3782(95)01674-0 · Cited by 177 · see citing works
Simerly, R. B. (1989) · Molecular Brain Research · doi:10.1016/0169-328x(89)90075-2 · Cited by 171 · see citing works
Learning in monkeys exposed perinatally to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
Schantz, S. L., & Bowman, R. E. (1989) · Neurotoxicology and Teratology · doi:10.1016/0892-0362(89)90080-9 · Cited by 168 · see citing works
Direct inhibition of tyrosine hydroxylase activity by catechol estrogens.
Lloyd, T., & Weisz, J. (1978) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)34622-7 · Cited by 167 · see citing works
Neurotoxicology : approaches and methods
Chang, L. W., & Slikker, W. (1995) · Cited by 161 · see citing works
Discovery and Epidemiology of PCB Poisoning in Taiwan: A Four-Year Followup
Hsu, S.-T., Ma, C., Hsu, S. K., Wu, S., Hsu, N. H., Yeh, C.-C., & Wu, S.-B. (1985) · Environmental Health Perspectives · doi:10.2307/3429867 · Cited by 160 · see citing works
Kodavanti, P. R. S., Shin, D. S., Tilson, H. A., & Harry, G. J. (1993) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1993.1226 · Cited by 158 · see citing works
Evans, M. S., Noguchi, G. E., & Rice, C. P. (1991) · Archives of Environmental Contamination and Toxicology · doi:10.1007/bf01065333 · Cited by 155 · see citing works
Schwartz, P. M., Jacobson, S. W., Fein, G. G., Jacobson, J. L., & Price, H. A. (1983) · American Journal of Public Health · doi:10.2105/ajph.73.3.293 · Cited by 153 · see citing works
Effects of prenatal PCB exposure on cognitive processing efficiency and sustained attention.
Jacobson, J. L., Jacobson, S., Padgett, R. J., Brumitt, G. A., & Billings, R. L. (1992) · Developmental Psychology · doi:10.1037/0012-1649.28.2.297 · Cited by 150 · see citing works
Polychlorinated Biphenyls (PCBs): Mammalian and Environmental Toxicology
(1987) · Environmental toxin series · doi:10.1007/978-3-642-70550-2 · Cited by 147 · see citing works
The effects of polychlorinated biphenyls given prenatally on the neurobehavioral development of mice
Tilson, H. A., Davis, G. J., McLachlan, J. A., & Lucier, G. W. (1979) · Environmental Research · doi:10.1016/0013-9351(79)90122-1 · Cited by 146 · see citing works
Taylor, P. R., Stelma, J. M., & Lawrence, C. (1989) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115143 · Cited by 138 · see citing works
Effects of perinatal PCB exposure on discrimination-reversal learning in monkeys
Schantz, S. L., Levin, E. D., Bowman, R. E., Heironimus, M. P., & Laughlin, N. K. (1989) · Neurotoxicology and Teratology · doi:10.1016/0892-0362(89)90066-4 · Cited by 133 · see citing works
Darnerud, P. O., Morse, D. C., Klasson‐Wehler, E., & Brouwer, A. (1996) · Toxicology · doi:10.1016/0300-483x(95)03169-g · Cited by 133 · see citing works
Hoffman, D. J., Rattner, B. A., Sileo, L., Docherty, D. E., & Kubiak, T. J. (1987) · Environmental Research · doi:10.1016/s0013-9351(87)80019-1 · Cited by 131 · see citing works
A 6-year follow-up of behavior and activity disorders in the Taiwan Yu-cheng children.
Chen, Y. C., Yu, M. L., Rogan, W. J., Gladen, B. C., & Hsu, C. C. (1994) · American Journal of Public Health · doi:10.2105/ajph.84.3.415 · Cited by 128 · see citing works
Neurotoxicology of PCBs and related compounds.
Rogan, W. J., & Gladen, B. C. (1992) · PubMed · Cited by 127 · see citing works
PCBs: Human and environmental hazards
Bennett, G. F. (1984) · Journal of Hazardous Materials · doi:10.1016/0304-3894(84)87018-1 · Cited by 125 · see citing works
Seegal, R. F., Bush, B., & Brosch, K. O. (1991) · PubMed · Cited by 122 · see citing works
Self-citationComparison of effects of Aroclors 1016 and 1260 on non-human primate catecholamine function
Seegal, R. F., Bush, B., & Brosch, K. O. (1991) · Toxicology · doi:10.1016/0300-483x(91)90215-m · Cited by 116 · see citing works
Self-citationFishman, L. M. (1990) · Topics in Geriatric Rehabilitation · doi:10.1097/00013614-199004000-00018 · Cited by 114 · see citing works
Age‐induced cognitive disturbances in Parkinson's disease
Dubois, B., Pillon, B., Sternić, N., Lhermitte, F., & Agid, Y. (1990) · Neurology · doi:10.1212/wnl.40.1.38 · Cited by 113 · see citing works
Silkworth, J. B. (1984) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(84)90086-3 · Cited by 110 · see citing works
Ryan, J. J., Levesque, D., Panopio, L. G., Sun, W. F., Masuda, Y., & Kuroki, H. (1993) · Archives of Environmental Contamination and Toxicology · doi:10.1007/bf01146170 · Cited by 110 · see citing works
Chen, Y.-J., & Hsu, C. (1994) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.1994.tb11851.x · Cited by 110 · see citing works
Sawaguchi, T., Matsumura, M., & Kubota, K. (1989) · Experimental Brain Research · doi:10.1007/bf00249897 · Cited by 109 · see citing works
Guo, Y. L., Lambert, G. H., & Hsu, C. C. (1995) · Environmental Health Perspectives · doi:10.1289/ehp.95103s6117 · Cited by 106 · see citing works
Schneider, J. S., & Roeltgen, D. P. (1993) · Brain Research · doi:10.1016/0006-8993(93)90049-s · Cited by 102 · see citing works
Kodavanti, P. R. S., Shafer, T. J., Ward, T. R., Mundy, W. R., Freudenrich, T. M., Harry, G. J., & Tilson, H. A. (1994) · Brain Research · doi:10.1016/0006-8993(94)90797-8 · Cited by 101 · see citing works
Cognitive performance in early Parkinson's disease
Hietanen, M., & Teräväinen, H. (2009) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1986.tb03257.x · Cited by 99 · see citing works
Eriksson, P., Lundkvist, U., & Fredriksson, A. (1991) · Toxicology · doi:10.1016/0300-483x(91)90150-y · Cited by 95 · see citing works
Estimation of the aqueous solubility of some aromatic compounds
Yalkowsky, S. H., Valvani, S. C., & Mackay, D. (1983) · Springer eBooks · doi:10.1007/978-1-4612-5462-1_5 · Cited by 95 · see citing works
Effects of Polychlorinated Biphenyls (PCBs) and Dioxins on Growth and Development
Sauer, P. J. J., Huisman, M., Koopman-Esseboom, C., Morse, D. C., Prooije, A. E. S.-V., van den Berg, K. J., Tuinstra, L. G. M. T., van der Paauw, C. G., Boersma, E. R., Weisglas‐Kuperus, N., et al. (1994) · Human & Experimental Toxicology · doi:10.1177/096032719401301213 · Cited by 92 · see citing works
Agrawal, A. K., Tilson, H. A., & Bondy, S. C. (1981) · Toxicology Letters · doi:10.1016/0378-4274(81)90087-4 · Cited by 90 · see citing works
NEUROPATHOLOGY OF "SPINNING SYNDROME" INDUCED BY PRENATAL INTOXICATION WITH A PCB IN MICE
Chou, S. M., Miike, T., Payne, W. M., & Davis, G. J. (1979) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1979.tb56619.x · Cited by 90 · see citing works
Kodavanti, P. R. S., Ward, T. R., McKinney, J. D., & Tilson, H. A. (1996) · Archives of Toxicology · doi:10.1007/s002040050254 · Cited by 90 · see citing works
Seegal, R. F., Bush, B., & Brosch, K. O. (1994) · Toxicology · doi:10.1016/0300-483x(94)90054-x · Cited by 87 · see citing works
Self-citationForeman, M. M., & Porter, J. C. (1980) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1980.tb09957.x · Cited by 86 · see citing works
Lindefors, N. (1993) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/0278-5846(93)90018-n · Cited by 85 · see citing works
Lilienthal, H. (1991) · Fundamental and Applied Toxicology · doi:10.1016/0272-0590(91)90226-t · Cited by 81 · see citing works
de Ku, L. M. J., Sharma-Stokkermans, M., & Meserve, L. A. (1994) · Toxicology · doi:10.1016/0300-483x(94)90025-6 · Cited by 75 · see citing works
Dopamine may influence striatal GABA release via three separate mechanisms
Bernáth, S., & Zigmond, M. J. (1989) · Brain Research · doi:10.1016/0006-8993(89)91262-6 · Cited by 74 · see citing works
Seegal, R. F., Brosch, K. O., Bush, B., Ritz, M., & Shain, W. G. (1989) · PubMed · Cited by 70 · see citing works
Self-citationIn utero PCB/PCDF exposure: Relation of developmental delay to dysmorphology and dose
Yu, M.-L., Hsu, C., Gladen, B. C., & Rogan, W. J. (1991) · Neurotoxicology and Teratology · doi:10.1016/0892-0362(91)90011-k · Cited by 70 · see citing works
Swanson, G. M., Ratcliffe, H. E., & Fischer, L. J. (1995) · Regulatory Toxicology and Pharmacology · doi:10.1006/rtph.1995.1018 · Cited by 70 · see citing works
Effects of 3,4,3′,4′-tetrachlorobiphenyl on thyroid function and histology in marmoset monkeys
van den Berg, K. J., ZURCHER, C., & Brouwer, A. (1988) · Toxicology Letters · doi:10.1016/0378-4274(88)90010-0 · Cited by 70 · see citing works
Behavioral effects of pre- and postnatal exposure to a mixture of low chlorinated PCBs in rats
Lilienthal, H. (1990) · Fundamental and Applied Toxicology · doi:10.1016/0272-0590(90)90032-f · Cited by 67 · see citing works
Historical changes in serum PCB and DDT levels in an environmentally-exposed cohort
Hovinga, M. E., Sowers, M., & Humphrey, H. E. B. (1992) · Archives of Environmental Contamination and Toxicology · doi:10.1007/bf00212554 · Cited by 65 · see citing works
Thyroid function in “Yusho” patients exposed to polychlorinated biphenyls (PCB)
Murai, K., Okamura, K., Tsuji, H., Kajiwara, E., Watanabe, H., Akagi, K., & Fujishima, M. (1987) · Environmental Research · doi:10.1016/s0013-9351(87)80226-8 · Cited by 62 · see citing works
Neurochemical and Behavioral Sequelae of Exposure to Dioxins and PCBs
Seegal, R. F., & Schantz, S. L. (1994) · Springer eBooks · doi:10.1007/978-1-4899-1462-0_13 · Cited by 60 · see citing works
Self-citationEffects of dioxins on thyroid function in newborn babies
Pluim, H. J., Koppe, J. G., Olie, K., van der Slikke, J. W., Kok, J. H., Vulsma, T., van Tijn, D. A., & de Vijlder, J. J. M. (1992) · The Lancet · doi:10.1016/0140-6736(92)91638-o · Cited by 60 · see citing works
Polychlorinated Biphenyls: Environmental Occurrence and Analysis
Safe, S. H., Safe, L. M., & Mullin, M. D. (1987) · Environmental toxin series · doi:10.1007/978-3-642-70550-2_1 · Cited by 56 · see citing works
Persistence of PCB congeners in capacitor workers and yusho patients
Brown, J. F., Lawton, R. W., Ross, M. R., Feingold, J., Wagner, R. E., & Hamilton, S. B. (1989) · Chemosphere · doi:10.1016/0045-6535(89)90417-7 · Cited by 56 · see citing works
Gierthy, J. F., & Crane, D. D. (1984) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(84)90274-6 · Cited by 54 · see citing works
Metabolism and biochemical effects of 3,3′,4,4′-tetrachlorobiphenyl in pregnant and fetal rats
Morse, D. C., Klasson‐Wehler, E., van de Pas, M., de Bie, A. T. H. J., van BLADEREN, P. J., & Brouwer, A. (1995) · Chemico-Biological Interactions · doi:10.1016/0009-2797(94)03347-1 · Cited by 52 · see citing works
Health status of Japanese and Taiwanese after exposure to contaminated rice oil.
Masuda, Y. (1985) · Environmental Health Perspectives · doi:10.1289/ehp.8560321 · Cited by 51 · see citing works
Neurotoxicology of ortho-substituted polychlorinated biphenyls
Seegal, R. F., Bush, B., & Shain, W. G. (1991) · Chemosphere · doi:10.1016/0045-6535(91)90042-c · Cited by 48 · see citing works
Self-citationBastomsky, C. H., & Murthy, P. V. N. S. (1976) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y76-004 · Cited by 45 · see citing works
Neurochemical and behavioral effects of polychlorinated biphenyls in mice.
Dl, R., & Martin, B. R. (1981) · PubMed · Cited by 40 · see citing works
The Neurochemical Effects of PCB Exposure are Age-Dependent
Seegal, R. F. (1994) · Springer eBooks · doi:10.1007/978-3-642-78640-2_15 · Cited by 39 · see citing works
Self-citationUse of toxins to disrupt neurotransmitter circuitry in the developing brain
Johnston, M. V., Barks, J., Greenamyre, T., & Silverstein, F. S. (1988) · Progress in brain research · doi:10.1016/s0079-6123(08)60519-1 · Cited by 32 · see citing works
Environmental factors altering thyroid function and their assessment.
Barsano, C. P. (1981) · Environmental Health Perspectives · doi:10.1289/ehp.813871 · Cited by 32 · see citing works
Bobovnikova, T., Dibtseva, A., Mitroshkov, A., & Pleskachevskaia, G. A. (1993) · The Science of The Total Environment · doi:10.1016/0048-9697(93)90033-3 · Cited by 31 · see citing works
Anaerobic biodegradation of polychlorinated biphenyls by bacteria from hudson river sediments
Chen, M., Hong, C.-S., Bush, B., & Rhee, G. (1988) · Ecotoxicology and Environmental Safety · doi:10.1016/0147-6513(88)90022-x · Cited by 30 · see citing works
Environmental biotechnology—reducing risks from environmental chemicals through biotechnology
Pawłowski, Ł. (1989) · Waste Management · doi:10.1016/0956-053x(89)90071-8 · Cited by 27 · see citing works
Halogenated biphenyls as AHH inducers: Effects of different halogen substituents
Bandiera, S. M., Sawyer, T. W., Campbell, M. A., Robertson, L. W., & Safe, S. H. (1982) · Life Sciences · doi:10.1016/0024-3205(82)90479-9 · Cited by 22 · see citing works
PC12 cells: a model system for studying drug effects on dopamine synthesis and release.
Kittner, B., Bräutigam, M., & Herken, H. (1987) · PubMed · Cited by 22 · see citing works
[Change of PCDF and PCB concentrations in the blood of Yucheng and Yusho patients for 25 years].
増田, 義., 原口, 浩., Kuroki, H., & Ryan, J. J. (1995) · PubMed · doi:10.15017/7323436 · Cited by 14 · see citing works
Residues of polychlorinated biphenyls (PCBs) in fish, water and sediment from Shing Mun River.
Chui, V. W. D., Lam-Leung, S. Y., & Chan, T. C. (1991) · PubMed · Cited by 12 · see citing works
Human colostrum as a source of organohalogen xenobiotics for a breast-fed neonate
Sikorski, R., Paskowski, T., Radomański, T., Niewiadowska, A., & Semeniuk, S. (1990) · Reproductive Toxicology · doi:10.1016/0890-6238(90)90074-6 · Cited by 12 · see citing works
Chapter 5: Polychlorinated biphenyls
(1994) · Regulatory Toxicology and Pharmacology · doi:10.1016/s0273-2300(05)80021-2 · Cited by 10 · see citing works
Kamal, M., Weisgerber, I., Klein, W., & KORTE, F. (1976) · Journal of Environmental Science and Health Part B · doi:10.1080/03601237609372043 · Cited by 9 · see citing works
Panek, D. U., Azzaro, A. J., Stitzel, R. E., & Head, R. J. (1987) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/bf00172791 · Cited by 6 · see citing works
[Change of PCDF concentrations in the blood of Yusho patients in recent ten years].
Masuda, Y., Kuroki, H., Haraguchi, K., Saito, H., & Jj, R. (1993) · PubMed · Cited by 1 · see citing works
Flagged first, then by citations
2 of the 130 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
sagvolden, T., johansen, E. B., aase, H., & russell, V. A. (2005) · Behavioral and Brain Sciences · doi:10.1017/s0140525x05000075 · Cited by 1,035 · see citing works
Brominated Flame Retardants: A Novel Class of Developmental Neurotoxicants in Our Environment?
Eriksson, P., Jakobsson, E., & Fredriksson, A. (2001) · Environmental Health Perspectives · doi:10.1289/ehp.01109903 · Cited by 585 · see citing works
Developmental neurotoxicity of polybrominated diphenyl ether (PBDE) flame retardants
COSTA, L., & GIORDANO, G. (2007) · NeuroToxicology · doi:10.1016/j.neuro.2007.08.007 · Cited by 578 · see citing works
Giesy, J. P., & Kannan, K. (1998) · Critical Reviews in Toxicology · doi:10.1080/10408449891344263 · Cited by 496 · see citing works
Effects of Environmental Synthetic Chemicals on Thyroid Function
Brücker-Davis, F. (1998) · Thyroid · doi:10.1089/thy.1998.8.827 · Cited by 476 · see citing works
Rusiecki, J. A., Baccarelli, A., Bollati, V., Tarantini, L., Moore, L. E., & Bonefeld-Jorgensen, E. C. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.11338 · Cited by 352 · see citing works
Walkowiak, J., Wiener, J. A., Fastabend, A., Heinzow, B., Krämer, U., Schmidt, E., Steingrüber, H.-J., Wundram, S., & Winneke, G. (2001) · The Lancet · doi:10.1016/s0140-6736(01)06654-5 · Cited by 352 · see citing works
Viberg, H. (2003) · Toxicology and Applied Pharmacology · doi:10.1016/s0041-008x(03)00217-5 · Cited by 340 · see citing works
Eriksson, P., Viberg, H., Jakobsson, E., Örn, U., & Fredriksson, A. (2002) · Toxicological Sciences · doi:10.1093/toxsci/67.1.98 · Cited by 318 · see citing works
Dingemans, M. M. L., van den Berg, M., & Westerink, R. H. S. (2011) · Environmental Health Perspectives · doi:10.1289/ehp.1003035 · Cited by 310 · see citing works
Easton, M. D. L., Luszniak, D., & der Geest, E. V. (2002) · Chemosphere · doi:10.1016/s0045-6535(01)00136-9 · Cited by 292 · see citing works
Thyroid-Disrupting Chemicals: Interpreting Upstream Biomarkers of Adverse Outcomes
Miller, M. D., Crofton, K. M., Rice, D. C., & Zoeller, R. T. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0800247 · Cited by 283 · see citing works
Comparison of polychlorinated biphenyl levels across studies of human neurodevelopment.
Longnecker, M. P., Wolff, M. S., Gladen, B. C., Brock, J. W., Grandjean, P., Jacobson, J. L., Korrick, S., Rogan, W. J., Weisglas‐Kuperus, N., Hertz‐Picciotto, I., et al. (2002) · Environmental Health Perspectives · doi:10.1289/ehp.5463 · Cited by 262 · see citing works
Meerts, I. A. T. M. (2002) · Toxicological Sciences · doi:10.1093/toxsci/68.2.361 · Cited by 260 · see citing works
Effects of polychlorinated biphenyls on the nervous system
FAROON, O. M., Jones, D. E., & Rosa, C. T. D. (2000) · Toxicology and Industrial Health · doi:10.1177/074823370001600708 · Cited by 240 · see citing works
Minding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicity
Pessah, I. N., Cherednichenko, G., & Lein, P. J. (2010) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2009.10.009 · Cited by 231 · see citing works
Mariussen, E., & Fonnum, F. (2003) · Neurochemistry International · doi:10.1016/s0197-0186(03)00044-5 · Cited by 231 · see citing works
Neurotoxicity of polychlorinated biphenyls and related organohalogens
Pessah, I. N., Lein, P. J., Seegal, R. F., & Sagiv, S. K. (2019) · Acta Neuropathologica · doi:10.1007/s00401-019-01978-1 · Cited by 222 · see citing works
Self-citationBreastfeeding, Exposure to Organochlorine Compounds, and Neurodevelopment in Infants
Ribas‐Fitó, N., Cardo, E., Sala, M., Muga, M., Mazón, C. S. M., Verdú, A., Kogevinas, M., Grimalt, J. O., & Sunyer, J. (2003) · PEDIATRICS · doi:10.1542/peds.111.5.e580 · Cited by 216 · see citing works
Sandau, C. D., Ayotte, P., Dewailly, É., Duffe, J. A., & Norstrom, R. J. (2000) · Environmental Health Perspectives · doi:10.1289/ehp.00108611 · Cited by 211 · see citing works
Hany, J., Lilienthal, H., Sarasin, A., Roth-Härer, A., Fastabend, A., Dunemann, L., LICHTENSTEIGER, W., & Winneke, G. (1999) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1999.8710 · Cited by 205 · see citing works
Prenatal PCB exposure and neonatal behavioral assessment scale (NBAS) performance
Stewart, P., Reihman, J., Lonky, E., Darvill, T., & Pagano, J. J. (2000) · Neurotoxicology and Teratology · doi:10.1016/s0892-0362(99)00056-2 · Cited by 200 · see citing works
Johansen, E. B., Aase, H., Meyer, A., & Sagvolden, T. (2002) · Behavioural Brain Research · doi:10.1016/s0166-4328(01)00434-x · Cited by 195 · see citing works
Dewailly, É., Mulvad, G., Pedersen, H. S., Ayotte, P., Demers, A., Weber, J. P., & Hansen, J. C. (1999) · Environmental Health Perspectives · doi:10.1289/ehp.99107823 · Cited by 183 · see citing works
Chauhan, K. R., Kodavanti, P. R. S., & McKinney, J. D. (2000) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1999.8826 · Cited by 180 · see citing works
Neurochemical Targets and Behavioral Effects of Organohalogen Compounds: An Update
Mariussen, E., & Fonnum, F. (2006) · Critical Reviews in Toxicology · doi:10.1080/10408440500534164 · Cited by 175 · see citing works
Fonnum, F., & Mariussen, E. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06427.x · Cited by 173 · see citing works
Keil, K. P., & Lein, P. J. (2016) · Environmental Epigenetics · doi:10.1093/eep/dvv012 · Cited by 167 · see citing works
Kodavanti, P. R. S. (2005) · Dose-Response · doi:10.2203/dose-response.003.03.002 · Cited by 160 · see citing works
Mariussen, E., & Fonnum, F. (2001) · Toxicology · doi:10.1016/s0300-483x(00)00374-7 · Cited by 151 · see citing works
Bemis, J. C., & Seegal, R. F. (1999) · Environmental Health Perspectives · doi:10.1289/ehp.99107879 · Cited by 149 · see citing works
Self-citationEriksson, P. O., Fischer, C., Wallin, M., Jakobsson, E., & Fredriksson, A. (2005) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2005.10.001 · Cited by 143 · see citing works
Eriksson, P., Fischer, C., & Fredriksson, A. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfl109 · Cited by 141 · see citing works
Klocke, C. R., & Lein, P. J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21031013 · Cited by 135 · see citing works
Mariussen, E., Myhre, O., Reistad, T., & Fonnum, F. (2002) · Toxicology and Applied Pharmacology · doi:10.1006/taap.2002.9353 · Cited by 133 · see citing works
Thyroid hormone-like and estrogenic activity of hydroxylated PCBs in cell culture
Kitamura, S., Jinno, N., Suzuki, T., Sugihara, K., Ohta, S., Kuroki, H., & Fujimoto, N. (2005) · Toxicology · doi:10.1016/j.tox.2004.11.037 · Cited by 128 · see citing works
Greer, C., Grygoruk, A., Patton, D., Ley, B., Romero‐Calderón, R., Chang, H.-Y., Houshyar, R., Bainton, R. J., DiAntonio, A., & Krantz, D. E. (2005) · Journal of Neurobiology · doi:10.1002/neu.20146 · Cited by 113 · see citing works
Park, J.-S., Linderholm, L., Charles, M. J., Athanasiadou, M., Petrı́k, J., Kočan, A., Drobná, B., Trnovec, T., Bergman, Å., & Hertz‐Picciotto, I. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.8913 · Cited by 112 · see citing works
Environmental Toxicant Effects on Neuroendocrine Function
Gore, A. C. (2001) · Endocrine · doi:10.1385/endo:14:2:235 · Cited by 111 · see citing works
Fonnum, F., Mariussen, E., & Reistad, T. (2005) · Journal of Toxicology and Environmental Health · doi:10.1080/15287390500259020 · Cited by 109 · see citing works
Kaya, H., Hany, J., Fastabend, A., Roth-Härer, A., Winneke, G., & Lilienthal, H. (2002) · Toxicology and Applied Pharmacology · doi:10.1006/taap.2001.9318 · Cited by 107 · see citing works
Vartiainen, T., Jaakkola, J. J. K., Saarikoski, S., & Tuomisto, J. T. (1998) · Environmental Health Perspectives · doi:10.1289/ehp.9810661 · Cited by 105 · see citing works
Branchi, I., Capone, F. T., Vitalone, A., Madia, F., Santucci, D., Alleva, E., & Costa, L. G. (2005) · NeuroToxicology · doi:10.1016/j.neuro.2004.11.005 · Cited by 101 · see citing works
Richardson, J. R. (2004) · Toxicology Letters · doi:10.1016/j.toxlet.2003.12.006 · Cited by 100 · see citing works
Strøm, M., Hansen, S., Olsen, S. F., Haug, L. S., Rantakokko, P., Kiviranta, H., & Halldorsson, T. I. (2014) · Environment International · doi:10.1016/j.envint.2014.03.002 · Cited by 98 · see citing works
Meerts, I. A. T. M. (2004) · Toxicological Sciences · doi:10.1093/toxsci/kfh252 · Cited by 98 · see citing works
Howard, A. (2003) · Toxicology and Applied Pharmacology · doi:10.1016/s0041-008x(03)00156-x · Cited by 112 · see citing works
Kodavanti, P. R. S., Kannan, N., Yamashita, N., Derr-Yellin, E. C., Ward, T. R., Burgin, D. E., Tilson, H. A., & Birnbaum, L. S. (2001) · Environmental Health Perspectives · doi:10.1289/ehp.011091153 · Cited by 97 · see citing works
Lee, D. W., & Opanashuk, L. A. (2004) · NeuroToxicology · doi:10.1016/j.neuro.2004.05.005 · Cited by 92 · see citing works
Toxicity of polychlorinated biphenyls in aquatic environments – A review
Ngoubeyou, P. S. K., Wolkersdorfer, C., Ndibewu, P. P., & Augustyn, W. A. (2022) · Aquatic Toxicology · doi:10.1016/j.aquatox.2022.106284 · Cited by 89 · see citing works
Zoeller, R. T., & Crofton, K. M. (2000) · PubMed · Cited by 89 · see citing works
Ross, P. S., & Birnbaum, L. S. (2003) · Human and Ecological Risk Assessment An International Journal · doi:10.1080/727073292 · Cited by 86 · see citing works
Lesiak, A., Zhu, M., Chen, H., Appleyard, S. M., Impey, S., Lein, P. J., & Wayman, G. A. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.2884-13.2014 · Cited by 85 · see citing works
“Dendritic spines are the primary site of excitatory synaptic input, and their formation is critical for normal neural function (Segal, 2005).”
BackgroundKodavanti, P. R. S., & Tilson, H. A. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06872.x · Cited by 85 · see citing works
Handal, A. J., Lozoff, B., Breilh, J., & Harlow, S. D. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.9261 · Cited by 81 · see citing works
Lein, P. J., Yang, D., Bachstetter, A. D., Tilson, H. A., Harry, G. J., Mervis, R. F., & Kodavanti, P. R. S. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.9773 · Cited by 81 · see citing works
Mariussen, E., Andersen, J. M., & Fonnum, F. (1999) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1999.8806 · Cited by 81 · see citing works
He, P., Wang, A., Xia, T., Gao, P., Niu, Q., Guo, L., Xu, B., & Chen, X. (2008) · NeuroToxicology · doi:10.1016/j.neuro.2008.10.004 · Cited by 80 · see citing works
Chiral polychlorinated biphenyls: absorption, metabolism and excretion—a review
Kania‐Korwel, I., & Lehmler, H. (2015) · Environmental Science and Pollution Research · doi:10.1007/s11356-015-4150-2 · Cited by 79 · see citing works
Practitioner Review: Early adversity and developmental disorders
Taylor, E., & Rogers, J. W. (2005) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2004.00402.x · Cited by 80 · see citing works
Kyriklaki, A., Vafeiadi, M., Kampouri, M., Koutra, K., Roumeliotaki, T., Chalkiadaki, G., Anousaki, D., Rantakokko, P., Kiviranta, H., Fthenou, E., et al. (2016) · Environment International · doi:10.1016/j.envint.2016.09.012 · Cited by 76 · see citing works
Lin, C., Juan, S., Wang, C. Y., Sun, Y., Chou, C., Chang, S., Hu, S.-Y., Lee, W., & Lee, Y. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.05098.x · Cited by 70 · see citing works
Meerts, I. A. T. M. (2004) · Toxicological Sciences · doi:10.1093/toxsci/kfh251 · Cited by 69 · see citing works
Faqi, A. S., Dalsenter, P. R., Merker, H. J., & Chahoud, I. (1998) · Human & Experimental Toxicology · doi:10.1177/096032719801700702 · Cited by 68 · see citing works
Are Endocrine Disrupting Compounds a Threat to Farm Animal Health, Welfare and Productivity?
Rhind, S. M. (2005) · Reproduction in Domestic Animals · doi:10.1111/j.1439-0531.2005.00594.x · Cited by 67 · see citing works
Kodavanti, P. R. S., Derr-Yellin, E. C., Mundy, W. R., Shafer, T. J., Herr, D. W., Barone, S., Choksi, N. Y., MacPhail, R. C., & Tilson, H. A. (1998) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1998.8533 · Cited by 66 · see citing works
Osteoclast markers accumulate on cells developing from human peripheral blood mononuclear precursors
Faust, J., Lacey, D., Hunt, P., Burgess, T. L., Scully, S. A., Van, G. Y., Eli, A., Qian, Y., & Shalhoub, V. (1999) · Journal of Cellular Biochemistry · doi:10.1002/(sici)1097-4644(19990101)72:1 · Cited by 105 · see citing works
Self-citationSánchez-Alonso, J. A. (2003) · Toxicology Letters · doi:10.1016/s0378-4274(03)00238-8 · Cited by 65 · see citing works
Mariussen, E., Andersson, P. L., Tysklind, M., & Fonnum, F. (2001) · Toxicology and Applied Pharmacology · doi:10.1006/taap.2001.9231 · Cited by 65 · see citing works
SIGNAL TRANSDUCTION IN ENVIRONMENTAL NEUROTOXICITY
Costa, L. G. (1998) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.38.1.21 · Cited by 62 · see citing works
Eriksson, P. E., & Fredriksson, A. (1998) · Environmental Toxicology and Pharmacology · doi:10.1016/s1382-6689(97)10002-3 · Cited by 61 · see citing works
Bushnell, P. J. (2002) · Toxicological Sciences · doi:10.1093/toxsci/68.1.109 · Cited by 61 · see citing works
He, P., Wang, A., Niu, Q., Guo, L., Xia, T., & Chen, X. (2010) · Toxicology and Industrial Health · doi:10.1177/0748233710387002 · Cited by 60 · see citing works
POLYCHLORINATED NAPHTHALENES AND OTHER ORGANOCHLORINE CONTAMINANTS IN HUMAN ADIPOSE AND LIVER TISSUE
Noren, C. W. K. (1998) · Journal of Toxicology and Environmental Health · doi:10.1080/009841098159295 · Cited by 60 · see citing works
Caspersen, I. H., Aase, H., Biele, G., Brantsæter, A. L., Haugen, M. A., Kvalem, H. E., Skogan, A. H., Zeiner, P., Alexander, J., Meltzer, H. M., et al. (2016) · Environment International · doi:10.1016/j.envint.2016.06.033 · Cited by 59 · see citing works
Hany, J., Lilienthal, H., Roth-Härer, A., Ostendorp, G., Heinzow, B., & Winneke, G. (1999) · Neurotoxicology and Teratology · doi:10.1016/s0892-0362(98)00038-5 · Cited by 58 · see citing works
Neurocognitive Changes among Elderly Exposed to PCBs/PCDFs in Taiwan
Lin, K., Guo, N., Tsai, P., Yang, C., & Guo, Y. L. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10134 · Cited by 56 · see citing works
Tofighi, R., Johansson, C. H., Goldoni, M., Ibrahim, W. N. W., Gogvadze, V. G., Mutti, A., & Ceccatelli, S. (2010) · Neurotoxicity Research · doi:10.1007/s12640-010-9159-1 · Cited by 55 · see citing works
Boix, J., Cauli, O., Leslie, H. A., & Felipo, V. (2010) · Neurochemistry International · doi:10.1016/j.neuint.2010.10.014 · Cited by 55 · see citing works
Fischer, C., Fredriksson, A., & Eriksson, P. (2007) · Toxicology · doi:10.1016/j.tox.2007.11.006 · Cited by 55 · see citing works
Chávez, F. P., Gordillo, F., & Jerez, C. A. (2006) · Biotechnology Advances · doi:10.1016/j.biotechadv.2005.11.007 · Cited by 55 · see citing works
Eriksson, P., Ankarberg, E. H., Viberg, H., & Fredriksson, A. (2001) · Neurotoxicity Research · doi:10.1007/bf03033229 · Cited by 53 · see citing works
Organochlorines, lead, and mercury in Akwesasne Mohawk youth.
Schell, L. M., Hubicki, L., DeCaprio, A. P., Gallo, M. V., Ravenscroft, J., Tarbell, A. M., Jacobs, A., David, D., Worswick, P., & Akwesasne Task Force on the Environment (2003) · Environmental Health Perspectives · doi:10.1289/ehp.5990 · Cited by 53 · see citing works
Immunologic and neurodevelopmental susceptibilities of autism
Pessah, I. N., Seegal, R. F., Lein, P. J., LaSalle, J., Yee, B. K., Van De Water, J., & Berman, R. F. (2008) · NeuroToxicology · doi:10.1016/j.neuro.2008.02.006 · Cited by 51 · see citing works
Self-citationGlynn, A. W., Atuma, S. S., Aune, M., Darnerud, P. O., & Cnattingius, S. (2001) · Environmental Research · doi:10.1006/enrs.2001.4270 · Cited by 51 · see citing works
Schell, L. M., Gallo, M. V., DeCaprio, A. P., Hubicki, L., Denham, M., & Ravenscroft, J. (2004) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2004.01.010 · Cited by 51 · see citing works
Human Exposure to Polychlorinated Biphenyls and Health Effects
Kimbrough, R. D., & Krouskas, C. A. (2003) · Toxicological Reviews · doi:10.2165/00139709-200322040-00004 · Cited by 49 · see citing works
Yu, K., He, Y., Yeung, L. W. Y., Lam, P. K. S., Wu, R. S. S., & Zhou, B. (2008) · Toxicological Sciences · doi:10.1093/toxsci/kfn088 · Cited by 47 · see citing works
Sánchez-Alonso, J. A., López‐Aparicio, P., Recio, M. N., & Pérez-Albarsanz, M. A. (2004) · Toxicology Letters · doi:10.1016/j.toxlet.2004.05.012 · Cited by 47 · see citing works
Sharma, R., & Kodavanti, P. R. S. (2002) · Toxicology and Applied Pharmacology · doi:10.1006/taap.2001.9328 · Cited by 47 · see citing works
Vuong, A. M., Xie, C., Jandarov, R., Dietrich, K. N., Zhang, H., Sjödin, A., Calafat, A. M., Lanphear, B. P., McCandless, L. C., Braun, J. M., et al. (2020) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2020.113527 · Cited by 46 · see citing works
Sinjari, T., & Darnerud, P. O. (1998) · Xenobiotica · doi:10.1080/004982598239722 · Cited by 46 · see citing works
Altmann, L. (2001) · Toxicological Sciences · doi:10.1093/toxsci/61.2.321 · Cited by 46 · see citing works
Pan, I., Daniels, J. L., Herring, A. H., Rogan, W. J., Siega‐Riz, A. M., Goldman, B. D., & Sjödin, A. (2010) · Paediatric and Perinatal Epidemiology · doi:10.1111/j.1365-3016.2010.01114.x · Cited by 45 · see citing works
Mammalian wildlife as complementary models in environmental neurotoxicology
Basu, N., & Head, J. A. (2009) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2008.12.005 · Cited by 45 · see citing works
Colciago, A., Negri‐Cesi, P., Pravettoni, A., Mornati, O., Casati, L., & Celotti, F. (2006) · Reproductive Toxicology · doi:10.1016/j.reprotox.2006.07.002 · Cited by 45 · see citing works
Brunelli, L., Llansola, M., Felipo, V., Campagna, R., Airoldi, L., Paola, M. D., Fanelli, R., Mariani, A., Mazzoletti, M., & Pastorelli, R. (2012) · Journal of Proteomics · doi:10.1016/j.jprot.2012.02.023 · Cited by 44 · see citing works
Royland, J. E., & Kodavanti, P. R. S. (2008) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2008.04.023 · Cited by 44 · see citing works
Zhou, T., Rademacher, D. J., Steinpreis, R. E., & Weis, J. S. (1999) · Comparative Biochemistry and Physiology Part C Pharmacology Toxicology and Endocrinology · doi:10.1016/s0742-8413(99)00077-8 · Cited by 41 · see citing works
Ortho substituted polychlorinated biphenyls elevate intracellular [Ca2+] in human granulocytes
Voie, Ø. A., & Fonnum, F. (1998) · Environmental Toxicology and Pharmacology · doi:10.1016/s1382-6689(97)10064-3 · Cited by 41 · see citing works
- Authors
- Seegal, R. F.
- Affiliations
- New York State Department of Health (US)
- Corresponding author
- Seegal, Richard F.
- Venue
- Critical Reviews in Toxicology
- Publisher
- Informa UK Limited
- Published
- 1996-01
- Volume
- 26
- Issue
- 6
- Pages
- 709-737
- ISSN
- 0045-6446 (ISSN-L)
- 1040-8444
- 1547-6898
- OpenAlex
- W1975003944
- Cited by
- 242
- References
- 130
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2023: 3 · 2022: 6 · 2021: 2 · 2020: 6 · 2019: 4 · 2018: 4 · 2017: 7 · 2016: 6 · 2015: 6 · 2014: 5 · 2013: 4 · 2012: 8
- FWCI
- 2.84
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Critical Reviews in Toxicology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Pesticide Exposure and Toxicity
- Keywords
- polychlorinated biphenyls, neurotoxicity, developmental neurotoxicity, prenatal exposure, lactational exposure, halogenated aromatic hydrocarbons, brain development, neurotransmitter synthesis, endocrine disruption, signal transduction, behavioral dysfunction, structure-activity relationship
- MeSH terms
- Adult, Animals, Humans, Infant, Nervous System Diseases, Polychlorinated Biphenyls
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review