The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.
Glutathione levels in human tumors
Open accessAbstract
This review summarizes clinical studies in which glutathione was measured in tumor tissue from patients with brain, breast, gastrointestinal, gynecological, head and neck and lung cancer. Glutathione tends to be elevated in breast, ovarian, head and neck, and lung cancer and lower in brain and liver tumors compared to disease-free tissue. Cervical, colorectal, gastric, and esophageal cancers show both higher and lower levels of tumor glutathione. Some studies show an inverse relationship between patient survival and tumor glutathione. Based on this survey, we recommend approaches that may improve the clinical value of glutathione as a biomarker.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
(2012) · Hepatogastroenterology · doi:10.5754/hge12469 · Cited by 3,178
Jones, D. P. (2006) · Antioxidants & Redox Signaling · doi:10.1089/ars.2006.8.1865 · Cited by 1,726
Glutathione dysregulation and the etiology and progression of human diseases
Ballatori, N., Krance, S. M., Notenboom, S., Shi, S., Tieu, K., & Hammond, C. L. (2009) · bchm · doi:10.1515/bc.2009.033 · Cited by 1,114
Normal alveolar epithelial lining fluid contains high levels of glutathione
Cantin, A. M., North, S. L., Hubbard, R. C., & Crystal, R. G. (1987) · Journal of Applied Physiology · doi:10.1152/jappl.1987.63.1.152 · Cited by 797
Chemotherapy-Associated Oxidative Stress: Impact on Chemotherapeutic Effectiveness
Conklin, K. A. (2004) · Integrative Cancer Therapies · doi:10.1177/1534735404270335 · Cited by 752
The cell cycle is a redox cycle: Linking phase-specific targets to cell fate
Burhans, W. C., & Heintz, N. H. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.05.026 · Cited by 361
Pope, W. B., Prins, R. M., Albert Thomas, M., Nagarajan, R., Yen, K. E., Bittinger, M. A., Salamon, N., Chou, A. P., Yong, W. H., Soto, H., et al. (2012) · Journal of Neuro-Oncology · doi:10.1007/s11060-011-0737-8 · Cited by 318
Lipid peroxidation and antioxidant status in colorectal cancer
Skrzydlewska, E. (2005) · World Journal of Gastroenterology · doi:10.3748/wjg.v11.i3.403 · Cited by 278
Hansen, R. E., & Winther, J. R. (2009) · Analytical Biochemistry · doi:10.1016/j.ab.2009.07.051 · Cited by 270
Genetic polymorphism and function of glutathione S-transferases in tumor drug resistance
Lo, H.-W., & Ali-Osman, F. (2007) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2007.06.009 · Cited by 216
Cited by
Hayes, J. D., Dinkova-Kostova, A. T., & Tew, K. D. (2020) · Cancer Cell · doi:10.1016/j.ccell.2020.06.001 · Cited by 2,654
Recent Strategies to Develop Innovative Photosensitizers for Enhanced Photodynamic Therapy
Pham, T. C., Nguyen, V.-N., Choi, Y., Lee, S., & Yoon, J. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00381 · Cited by 1,813
Niu, B., Liao, K., Zhou, Y., Wen, T., Quan, G., Pan, X., & Wu, C. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.121110 · Cited by 1,168
Smart nanocarrier-based drug delivery systems for cancer therapy and toxicity studies: A review
Hossen, S., Hossain, M. K., Basher, M. K., Mia, M. N. H., Rahman, M. T., & Uddin, M. J. (2019) · Journal of Advanced Research · doi:10.1016/j.jare.2018.06.005 · Cited by 998
Role of Glutathione in Cancer: From Mechanisms to Therapies
Kennedy, L., Sandhu, J. K., Harper, M.-E., & Cuperlovic-Culf, M. (2020) · Biomolecules · doi:10.3390/biom10101429 · Cited by 880
Metadata
- Authors
- Gamcsik, M. P., Kasibhatla, M. S., Teeter, S. D., & Colvin, O. M.
- Venue
- Biomarkers
- Publisher
- Informa UK Limited
- Published
- 2012-08-20
- Volume
- 17
- Issue
- 8
- Pages
- 671-691
- ISSN
- 1354-750X (ISSN-L)
- 1366-5804
- OpenAlex
- W1980780168
- Cited by
- 600
- References
- 65
- FWCI
- 3.64
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Glutathione levels in human tumors. https://app.cochat.ai/papers/10.3109/1354750x.2012.715672
- The paper
- Gamcsik, M. P., Kasibhatla, M. S., Teeter, S. D., & Colvin, O. M. (2012). Glutathione levels in human tumors. Biomarkers. https://doi.org/10.3109/1354750x.2012.715672
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
