Cited by 131Attention Deficit Hyperactivity DisorderSchizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

The DOI matches its Crossref record; 42 of the 43 references it cites were found in a registry or an index.

Twenty-four-week treatment with extended release methylphenidate improves emotional symptoms in adult ADHD

Rösler, Michael, Retz, Wolfgang, Fischer, Roland, Ose, Claudia, Alm, Barbara, Deckert, Jürgen, Philipsen, Alexandra, Herpertz, Sabine, Ammer, Richard·2010·The World Journal of Biological Psychiatry

DOI 10.3109/15622971003624197

Open this paper in CoChat — free account

Abstract

OBJECTIVES: Treatment investigations with methylphenidate in adults with ADHD focus preferentially on the classical psychopathology: inattention, hyperactivity and impulsivity. ADHD-associated emotional symptoms, which are frequently present at least in ADHD subpopulations, were studied rarely. The vast majority of the placebo-controlled trials had observation periods between 4 and 8 weeks. To assess the medium- to long-term effects of extended release methylphenidate (MPH-ER) on emotional symptoms and other psychopathology frequently seen in ADHD patients, we conducted a large-scale, multicenter treatment study. METHODS: We performed a randomised, 24-week, double-blind, placebo-controlled study in adults with ADHD. The diagnosis was made on the basis of the DSM-IV criteria, which were confirmed by clinical history and a structured psychopathological interview and the use of rating instruments. 363 patients were randomized to MPH-ER or placebo at a ratio of 2:1. The duration of the titration period was 5 weeks followed by a maintainance phase of 19 weeks. The efficacy measures were the observer rated 10-item Emotional Dysregulation Scale (EDS) derived from the Wender-Reimherr Adult Attention Deficit Disorder Scale (WRAADDS) and a self-report, six-item Emotional Lability Scale (ELS) extracted from the long version of the Conners Adult ADHD Self Report Scale (CAARS:S:L). In addition we used the SCL-90-R for the assessment of ADHD associated and comorbid psychopathology. RESULTS: MPH-ER was statistically superior to placebo in reducing emotional symptoms as assessed by the EDS and the ELS. Obsessive-compulsive symptoms and those of problems with self-concept declined until the end of the observation period. The decline was more pronounced in MPH-ER treated individuals. The effects remained robust during the entire maintenance period until week 24. Symptoms of anxiety, depression, anger and hostility, phobia, paranoid ideations and psychoticism were not improved. CONCLUSIONS: MPH-ER appears to be an efficacious treatment for emotional symptoms with ADHD. Also obsessive-compulsive symptoms and problems with self-concept were affected positively.

Integrity signals

Registry

Crossref · 10.3109/15622971003624197

Cites

42 of 42 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Untitled work
(1998) · Cited by 2,026
Age-dependent decline of symptoms of attention deficit hyperactivity disorder: impact of remission definition and symptom type
Biederman, J. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.5.816 · Cited by 1,498
Adult Outcome of Hyperactive Boys: Educational Achievement, Occupational Rank, and Psychiatric Status
Mannuzza, S. (1993) · Archives of General Psychiatry · doi:10.1001/archpsyc.1993.01820190067007 · Cited by 1,368
Cross-national prevalence and correlates of adult attention-deficit hyperactivity disorder
Fayyad, J., De Graaf, R., Kessler, R., Alonso, J., Angermeyer, M., Demyttenaere, K., De Girolamo, G., Haro, J. M., Karam, E. G., Lara, C., et al. (2007) · British Journal of Psychiatry · doi:10.1192/bjp.bp.106.034389 · Cited by 1,321
Pharmacotherapy of Attention-Deficit Hyperactivity Disorder across the Life Cycle
SPENCER, T., BIEDERMAN, J., WILENS, T., HARDING, M., O'DONNELL, D., & GRIFFIN, S. (1996) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199604000-00008 · Cited by 830
Atomoxetine in adults with ADHD: two randomized, placebo-controlled studies
Michelson, D., Adler, L., Spencer, T., Reimherr, F. W., West, S. A., Allen, A. J., Kelsey, D., Wernicke, J., Dietrich, A., & Milton, D. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01671-2 · Cited by 790
SKID I. Strukturiertes Klinisches Interview für DSM-IV. Achse I: Psychische Störungen. Interviewheft und Beurteilungsheft. Eine deutschsprachige, erweiterte Bearb. d. amerikanischen Originalversion des SKID I
Wïttchen, H., Wunderlich, U., Gruschwitz, S., & Zaudig, M. (1997) · Max Planck Institute for Plasma Physics · Cited by 769
Psychiatric status of hyperactives as adults: a controlled prospective 15-year follow-up of 63 hyperactive children
WEISS, G., HECHTMAN, L., MILROY, T., & PERLMAN, T. (1985) · Journal of the American Academy of Child Psychiatry · doi:10.1016/s0002-7138(09)60450-7 · Cited by 753
ATTENTION-DEFICIT HYPERACTIVITY DISORDER IN ADULTS
Wender, P. H. (1998) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(05)70039-3 · Cited by 728
Prevalence, Clinical Correlates, and Longitudinal Course of Severe Mood Dysregulation in Children
Brotman, M. A., Schmajuk, M., Rich, B. A., Dickstein, D. P., Guyer, A. E., Costello, E. J., EGGER, H. L., Angold, A. C., Pine, D. S., & Leibenluft, E. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.08.042 · Cited by 491

Show all 43 references

Research works printed but not linked: 2

Biederman J, 2004, J Clin Psychiatry, 65, 3
Weiss MD, 2004, J Clin Psychiatry, 65, 27

Sorted by citations

Emotion Dysregulation in Attention Deficit Hyperactivity Disorder
Shaw, P., Stringaris, A., Nigg, J., & Leibenluft, E. (2014) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2013.13070966 · Cited by 1,232
Adult ADHD and comorbid disorders: clinical implications of a dimensional approach
Katzman, M. A., Bilkey, T. S., Chokka, P. R., Fallu, A., & Klassen, L. J. (2017) · BMC Psychiatry · doi:10.1186/s12888-017-1463-3 · Cited by 732
A Review of Heterogeneity in Attention Deficit/Hyperactivity Disorder (ADHD)
Luo, Y., Weibman, D., Halperin, J. M., & Li, X. (2019) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2019.00042 · Cited by 394
Practitioner Review: Emotional Dysregulation in Attention-deficit/Hyperactivity Disorder—Implications for Clinical Recognition and Intervention
Faraone, S. V., Rostain, A. L., Blader, J., Busch, B., Childress, A. C., Connor, D. F., & Newcorn, J. H. (2019) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12899 · Cited by 400
Maternal emotion and cognitive control capacities and parenting: A conceptual framework
Crandall, A., Deater-Deckard, K. D., & Riley, A. W. (2015) · Developmental Review · doi:10.1016/j.dr.2015.01.004 · Cited by 417
Adult attention-deficit hyperactivity disorder: key conceptual issues
Asherson, P., Buitelaar, J., Faraone, S. V., & Rohde, L. A. (2016) · The Lancet Psychiatry · doi:10.1016/s2215-0366(16)30032-3 · Cited by 347
Evidence-based guidelines for the pharmacological management of attention deficit hyperactivity disorder: update on recommendations from the British Association for Psychopharmacology
Bolea-Alamañac, B., Nutt, D. J., Adamou, M., Asherson, P., Bazire, S., Coghill, D., Heal, D., Müller, U., Nash, J., Santosh, P., et al. (2014) · Journal of Psychopharmacology · doi:10.1177/0269881113519509 · Cited by 287
Emotion dysregulation in adults with attention deficit hyperactivity disorder: a meta-analysis
Beheshti, A., Chavanon, M.-L., & Christiansen, H. (2020) · BMC Psychiatry · doi:10.1186/s12888-020-2442-7 · Cited by 247
Emotional lability, comorbidity and impairment in adults with attention-deficit hyperactivity disorder
Skirrow, C., & Asherson, P. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.10.011 · Cited by 230
Long-term efficacy and safety of treatment with stimulants and atomoxetine in adult ADHD: A review of controlled and naturalistic studies
Fredriksen, M., Halmøy, A., Faraone, S. V., & Haavik, J. (2013) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2012.07.016 · Cited by 173
Emotional dysregulation in adult ADHD: what is the empirical evidence?
Retz, W., Stieglitz, R., Corbisiero, S., Retz‐Junginger, P., & Rösler, M. (2012) · Expert Review of Neurotherapeutics · doi:10.1586/ern.12.109 · Cited by 188
Understanding deficient emotional self-regulation in adults with attention deficit hyperactivity disorder: a controlled study
Surman, C. B. H., Biederman, J., Spencer, T., Miller, C. A., McDermott, K. M., & Faraone, S. V. (2013) · ADHD Attention Deficit and Hyperactivity Disorders · doi:10.1007/s12402-012-0100-8 · Cited by 155
Pharmacotherapy of emotional dysregulation in adults with ADHD: a systematic review and meta-analysis
Lenzi, F., Cortese, S., Harris, J., & Masi, G. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.08.010 · Cited by 141
Is emotional dysregulation part of the psychopathology of ADHD in adults?
Corbisiero, S., Stieglitz, R.-D., Retz, W., & Rösler, M. (2013) · ADHD Attention Deficit and Hyperactivity Disorders · doi:10.1007/s12402-012-0097-z · Cited by 139
Differential diagnosis, comorbidity, and treatment of attention-deficit/hyperactivity disorder in relation to bipolar disorder or borderline personality disorder in adults
Asherson, P. J., Young, A. H., Eich‐Höchli, D., Moran, P., Porsdal, V., & Deberdt, W. G. (2014) · Current Medical Research and Opinion · doi:10.1185/03007995.2014.915800 · Cited by 140
An update on the pharmacotherapy of attention-deficit/hyperactivity disorder in adults
Wilens, T. E., Morrison, N. R., & Prince, J. B. (2011) · Expert Review of Neurotherapeutics · doi:10.1586/ern.11.137 · Cited by 117
ADHD and Anxiety: Clinical Significance and Treatment Implications
Reimherr, F. W., Marchant, B. K., Gift, T. E., & Steans, T. A. (2017) · Current Psychiatry Reports · doi:10.1007/s11920-017-0859-6 · Cited by 113
ADHD in Children and Adults: Diagnosis and Prognosis
Leffa, D. T., Caye, A., & Rohde, L. A. (2022) · Current topics in behavioral neurosciences · doi:10.1007/7854_2022_329 · Cited by 127
An update on the debated association between ADHD and bipolar disorder across the lifespan
Skirrow, C., Hosang, G. M., FARMER, A. E., & Asherson, P. J. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.04.003 · Cited by 112
Emotional Dysregulation in Adults With Attention‐Deficit/Hyperactivity Disorder–Validity, Predictability, Severity, and Comorbidity
Corbisiero, S., Mörstedt, B., Bitto, H., & Stieglitz, R. (2016) · Journal of Clinical Psychology · doi:10.1002/jclp.22317 · Cited by 96
Adult ADHD: A new disease?
Zalsman, G., & Shilton, T. (2016) · International Journal of Psychiatry in Clinical Practice · doi:10.3109/13651501.2016.1149197 · Cited by 103
Attention-deficit/hyperactivity disorder in elite athletes: a narrative review
Han, D. H., Mcduff, D. R., Thompson, D., Hitchcock, M., Reardon, C. L., & Hainline, B. W. (2019) · British Journal of Sports Medicine · doi:10.1136/bjsports-2019-100713 · Cited by 95
Genetic Associations Between the Symptoms of Attention-Deficit/Hyperactivity Disorder and Emotional Lability in Child and Adolescent Twins
Merwood, A., Chen, W., Rijsdijk, F., Skirrow, C., Larsson, H., Thapar, A., Kuntsi, J., & Asherson, P. (2014) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2013.11.006 · Cited by 84
Pharmacological interventions for adolescents and adults with ADHD: stimulant and nonstimulant medications and misuse of prescription stimulants
Weyandt, L. L., Oster, D. R., Marraccini, M. E., Guðmundsdóttir, B. G., Munro, B. A., Zavras, B. M., & Kuhar, B. G. (2014) · Psychology Research and Behavior Management · doi:10.2147/prbm.s47013 · Cited by 95
Multiscale assessment of treatment efficacy in adults with ADHD: A randomized placebo-controlled, multi-centre study with extended-release methylphenidate
Retz, W., Rösler, M., Ose, C., Scherag, A., Alm, B., Philipsen, A., Fischer, R., Ammer, R., & The Study Group (2012) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2010.540257 · Cited by 79
Using Stimulants to Treat ADHD-Related Emotional Lability
Posner, J., Kass, E., & Hulvershorn, L. (2014) · Current psychiatry reports · doi:10.1007/s11920-014-0478-4 · Cited by 66
Irritability in children and adolescents: past concepts, current debates, and future opportunities
Krieger, F., Leibenluft, E., Stringaris, A. K., & Polanczyk, G. V. (2013) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2013-s107 · Cited by 68
Effectiveness of one-year pharmacological treatment of adult attention-deficit/hyperactivity disorder (ADHD): An open-label prospective study of time in treatment, dose, side-effects and comorbidity
Fredriksen, M., Dahl, A. A., Martinsen, E. W., Klungsøyr, O., Haavik, J., & Peleikis, D. E. (2014) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2014.09.013 · Cited by 65
Efficacy of Cognitive Behavioral Therapy With and Without Medication for Adults With ADHD: A Randomized Clinical Trial
Cherkasova, M. V., French, L. R., Syer, C. A., Cousins, L. S., Galina, H., Ahmadi-Kashani, Y., & Hechtman, L. T. (2016) · Journal of Attention Disorders · doi:10.1177/1087054716671197 · Cited by 70
Exome sequencing and unrelated findings in the context of complex disease research: ethical and clinical implications.
Lyon, G. J., Jiang, T., van Wijk, R., Wang, W., Bodily, P., Xing, J., Tian, L., Robison, R. J., Clement, M., Yang, L., et al. (2011) · PubMed · Cited by 57
Effects of stimulants and atomoxetine on emotional lability in adults: A systematic review and meta-analysis
Moukhtarian, T. R., Cooper, R. E., Vassos, E., Moran, P., & Asherson, P. (2017) · European Psychiatry · doi:10.1016/j.eurpsy.2017.05.021 · Cited by 56
Long-Term Outcomes with Medications for Attention-Deficit Hyperactivity Disorder
Huang, Y., & Tsai, M.-H. (2011) · CNS Drugs · doi:10.2165/11589380-000000000-00000 · Cited by 54
Normalisation of frontal theta activity following methylphenidate treatment in adult attention-deficit/hyperactivity disorder
Skirrow, C., McLoughlin, G., Banaschewski, T., Brandeis, D., Kuntsi, J., & Asherson, P. J. (2014) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2014.09.015 · Cited by 50
Types of adult attention-deficit hyperactivity disorder (ADHD): baseline characteristics, initial response, and long-term response to treatment with methylphenidate
Reimherr, F. W., Marchant, B. K., Gift, T. E., Steans, T. A., & Wender, P. H. (2015) · ADHD Attention Deficit and Hyperactivity Disorders · doi:10.1007/s12402-015-0176-z · Cited by 59
Six-year follow-up study of combined type ADHD from childhood to young adulthood: Predictors of functional impairment and comorbid symptoms
Cadman, T., Findon, J. L., Eklund, H., Hayward, H., Howley, D., Cheung, C. H. M., Kuntsi, J., Glaser, K., Murphy, D., & Asherson, P. J. (2016) · European Psychiatry · doi:10.1016/j.eurpsy.2015.08.007 · Cited by 59
Long-term open-label response to atomoxetine in adult ADHD: influence of sex, emotional dysregulation, and double-blind response to atomoxetine
Marchant, B. K., Reimherr, F. W., Halls, C., Williams, E. D., Strong, R. E., Kondo, D. G., Soni, P., & Robison, R. J. (2011) · ADHD Attention Deficit and Hyperactivity Disorders · doi:10.1007/s12402-011-0054-2 · Cited by 49
Exploring deficient emotion regulation in adult ADHD: electrophysiological evidence
Shushakova, A., Ohrmann, P., & Pedersen, A. (2017) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-017-0826-6 · Cited by 50
Attention deficit/hyperactivity disorder symptoms in Italian bipolar adult patients: a preliminary report.
Perugi, G., Ceraudo, G., Vannucchi, G., Rizzato, S., Toni, C., & Dell'Osso, L. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.12.010 · Cited by 46
Emotion Dysregulation in Attention Deficit Hyperactivity Disorder
Shaw, P., Stringaris, A. K., Nigg, J. T., & Leibenluft, E. (2016) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.140102 · Cited by 53
Emotion dysregulation in attention-deficit/hyperactivity disorder and borderline personality disorder
Moukhtarian, T. R., Mintah, R. S., Moran, P., & Asherson, P. J. (2018) · Borderline Personality Disorder and Emotion Dysregulation · doi:10.1186/s40479-018-0086-8 · Cited by 54
The use of stimulant medications for non-core aspects of ADHD and in other disorders
Sinita, E., & Coghill, D. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.06.014 · Cited by 43
Validation of the Expanded Versions of the Adult ADHD Self-Report Scale v1.1 Symptom Checklist and the Adult ADHD Investigator Symptom Rating Scale
Silverstein, M. J., Faraone, S. V., Alperin, S., Leon, T. L., Biederman, J., Spencer, T. J., & Adler, L. A. (2018) · Journal of Attention Disorders · doi:10.1177/1087054718756198 · Cited by 43
Addressing the lack of studies in attention-deficit/hyperactivity disorder in adults
Ramos‐Quiroga, J. A., Nasillo, V., Fernández‐Aranda, F., & Casas, M. (2014) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.2014.908708 · Cited by 44
La dysrégulation émotionnelle est-elle une des composantes du trouble déficit d’attention/hyperactivité ?
Villemonteix, T., Purper‐Ouakil, D., & Romo, L. (2014) · L Encéphale · doi:10.1016/j.encep.2013.12.004 · Cited by 48
Neurobiological and psychophysiological correlates of emotional dysregulation in ADHD patients
Herrmann, M. J., Biehl, S. C., Jacob, C., & Deckert, J. (2010) · ADHD Attention Deficit and Hyperactivity Disorders · doi:10.1007/s12402-010-0047-6 · Cited by 42
Emotional lability: The discriminative value in the diagnosis of attention deficit/hyperactivity disorder in adults
Vidal, R., Valero, S., Nogueira, M., Palomar, G., Corrales, M., Richarte, V., Bosch, R., Gómez-Barros, N., Corominas, M., Casas, M., et al. (2014) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2014.07.001 · Cited by 36
Pharmacological treatment of adult ADHD in Europe
Retz, W., Retz‐Junginger, P., Thome, J., & Rösler, M. (2011) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2011.603229 · Cited by 37
Emotional dysregulation and health related quality of life in young adults with ADHD: A cross sectional study
Ben-Dor Cohen, M., Eldar, E., Maeir, A., & Nahum, M. (2021) · Health and Quality of Life Outcomes · doi:10.1186/s12955-021-01904-8 · Cited by 35
The use of stimulants and atomoxetine in adults with comorbid ADHD and bipolar disorder
Perugi, G., & Vannucchi, G. (2015) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2015.1079620 · Cited by 38
Six months methylphenidate treatment improves emotion dysregulation in adolescents with attention deficit/hyperactivity disorder: a prospective study
Gamlı, İ. S., & Tahiroğlu, A. Y. (2018) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s164807 · Cited by 35
Violent offending in borderline personality disorder and attention deficit/hyperactivity disorder
Sebastian, A., Retz, W., Tüscher, O., & Turner, D. (2019) · Neuropharmacology · doi:10.1016/j.neuropharm.2019.03.008 · Cited by 35
Current and emerging pharmacotherapy for the treatment of adult attention deficit hyperactivity disorder (ADHD)
Perugi, G., Pallucchini, A., Rizzato, S., Pinzone, V., & Rossi, P. D. (2019) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2019.1618270 · Cited by 35
Four-Year Outcome in Psychopharmacologically Treated Adults With Attention-Deficit/Hyperactivity Disorder
Lensing, M. B., Zeiner, P., Sandvik, L., & Opjordsmoen, S. (2013) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.12m07714 · Cited by 32
Long‐Term Pharmacotherapy of Adults With Attention Deficit Hyperactivity Disorder: A Literature Review and Clinical Study
Fredriksen, M., & Peleikis, D. E. (2015) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.12477 · Cited by 31
Prediction of methylphenidate treatment outcome in adults with attention-deficit/hyperactivity disorder (ADHD)
Retz, W., & Retz‐Junginger, P. (2014) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-014-0542-4 · Cited by 34
Treatment adherence and persistence in adult ADHD: Results from a twenty-four week controlled clinical trial with extended release methylphenidate
Sobanski, E., Retz, W., Fischer, R., Ose, C., Alm, B., Hennig, O., & Rösler, M. (2014) · European psychiatry · doi:10.1016/j.eurpsy.2013.08.004 · Cited by 32
Pharmacological treatment of attention-deficit/hyperactivity disorder: assessing outcomes
Adamo, N., Seth, S., & Coghill, D. (2015) · Expert Review of Clinical Pharmacology · doi:10.1586/17512433.2015.1050379 · Cited by 31
Correlation of symptomatic improvements with functional improvements and patient-reported outcomes in adults with attention-deficit/hyperactivity disorder treated with OROS methylphenidate
Rösler, M., Ginsberg, Y., Arngrim, T., Adamou, M., Niemelä, A., Dejonkheere, J., van Oene, J., & Schäuble, B. (2011) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2011.571283 · Cited by 28
The Psychopharmacology Algorithm Project at the Harvard South Shore Program: An Update on Unipolar Nonpsychotic Depression
Giakoumatos, C. I., & Osser, D. N. (2019) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000197 · Cited by 27
Emotional symptoms and their contribution to functional impairment in adults with attention-deficit/hyperactivity disorder
Mörstedt, B., Corbisiero, S., Bitto, H., & Stieglitz, R. (2015) · ADHD Attention Deficit and Hyperactivity Disorders · doi:10.1007/s12402-015-0181-2 · Cited by 26
The effects of atomoxetine on emotional control in adults with ADHD: An integrated analysis of multicenter studies
Asherson, P. J., Stes, S., Markhed, M. N., Berggren, L., Svanborg, P., Kutzelnigg, A., & Deberdt, W. G. (2015) · European Psychiatry · doi:10.1016/j.eurpsy.2014.12.002 · Cited by 25
Attention-deficit/hyperactivity disorder in adults: update on clinical presentation and care
Asherson, P. J., Manor, I., & Huß, M. (2014) · Neuropsychiatry · doi:10.2217/npy.14.16 · Cited by 27
Emotional Lability in Patients with Attention-Deficit/Hyperactivity Disorder: Impact of Pharmacotherapy
Childress, A. C., & Sallee, F. R. (2015) · CNS Drugs · doi:10.1007/s40263-015-0264-9 · Cited by 23
Methylphenidate HCL for the treatment of ADHD in children and adolescents
Childress, A. C. (2016) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2016.1182986 · Cited by 23
Methylphenidate Use for Emotional Dysregulation in Children and Adolescents with ADHD and ADHD and ASD: A Naturalistic Study
Ventura, P., de Giambattista, C., Trerotoli, P., Cavone, M., Di Gioia, A., & Margari, L. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11102922 · Cited by 22
Cortisol awakening response in adults with attention deficit hyperactivity disorder: Subtype differences and association with the emotional lability
Ramos‐Quiroga, J. A., Corominas, M., Gloria Palomar, A., Ferrer, R., Valero, S., Montse Corrales, F., Vanesa Richarte, B., & Casas, M. (2016) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2016.03.014 · Cited by 19
Randomised controlled trial of the short-term effects of OROS-methylphenidate on ADHD symptoms and behavioural outcomes in young male prisoners with attention-deficit/hyperactivity disorder (CIAO-II)
Asherson, P. J., Johansson, L. C., Holland, R., Fahy, T., Forester, A., Howitt, S., Lawrie, S. M., Strang, J., Young, S., Landau, S., et al. (2019) · Trials · doi:10.1186/s13063-019-3705-9 · Cited by 18
Perpetration of and Victimization in Cyberbullying and Traditional Bullying in Adolescents with Attention-Deficit/Hyperactivity Disorder: Roles of Impulsivity, Frustration Intolerance, and Hostility
Liu, T., Hsiao, R. C.-J., Chou, W., & Yen, C. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18136872 · Cited by 18
Identifying different patterns of emotion dysregulation in adult ADHD
Martz, É., Weiner, L., & Weibel, S. (2023) · Borderline Personality Disorder and Emotion Dysregulation · doi:10.1186/s40479-023-00235-y · Cited by 25
Self-Reported Depressive Symptoms and Suicidality in Adolescents with Attention-Deficit/Hyperactivity Disorder: Roles of Bullying Involvement, Frustration Intolerance, and Hostility
Liu, T., Hsiao, R. C.-J., Chou, W., & Yen, C. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18157829 · Cited by 28
Revisiting stimulant use for emotional dysregulation in attention-deficit/hyperactivity disorder (ADHD)
Brancati, G. E., Acierno, D., Barbuti, M., Elefante, C., Gemignani, S., Raia, A., & Perugi, G. (2023) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2023.2263645 · Cited by 16
Psychometric Properties of the Self-Report Wender-Reimherr Adult Attention Deficit Disorder Scale
Marchant, B. K., Reimherr, F. W., Wender, P. H., & Gift, T. E. (2015) · Annals of Clinical Psychiatry · doi:10.1177/104012371502700406 · Cited by 16
Extended-release methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults
Boesen, K., Paludan‐Müller, A. S., Gøtzsche, P. C., & Jørgensen, K. J. (2022) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012857.pub2 · Cited by 23
Stimulants, cognition and ADHD
Baroni, A., & Castellanos, F. X. (2015) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2015.04.010 · Cited by 14
The Impact of Emotional Lability Symptoms During Childhood in Adults With ADHD
Gisbert, L., Vanesa Richarte, B., Montse Corrales, F., Ibáñez, P., Bosch, R., Casas, M., & Ramos‐Quiroga, J. A. (2017) · Journal of Attention Disorders · doi:10.1177/1087054717719534 · Cited by 16
The Relationship Between Neuropsychological Deficits and Emotional Lability in Adults With ADHD
Gisbert, L., Vanesa Richarte, B., Montse Corrales, F., Ibáñez, P., Bosch, R., Bellina, M., Fadeuilhe, C., Casas, M., & Ramos‐Quiroga, J. A. (2018) · Journal of Attention Disorders · doi:10.1177/1087054718780323 · Cited by 14
Methylphenidate–risperidone combination in child psychiatry: A retrospective analysis of 44 cases
Javelot, H., Glay-Ribau, C., Ligier, F., Weiner, L., Didelot, N., Messaoudi, M., Socha, M., Lawson, F. B., & Kabuth, B. (2014) · Annales Pharmaceutiques Françaises · doi:10.1016/j.pharma.2013.12.009 · Cited by 13
Lower Cardiac Vagal Activity Predicts Self-Reported Difficulties With Emotion Regulation in Adolescents With ADHD
Kvadsheim, E., Fasmer, O. B., Osnes, B., Koenig, J., Adólfsdóttir, S., Eichele, H., Plessen, K. J., & Sørensen, L. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00244 · Cited by 11
Relationship Between ADHD-Like Traits and Emotion Dysregulation in the Adult General Population
Albesisi, S., & Overton, P. G. (2023) · Advances in Neurodevelopmental Disorders · doi:10.1007/s41252-023-00381-y · Cited by 13
Duygular ve Psikolojik Belirtiler Arasındaki İlişkiler
Vatan, S. (2016) · Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry · doi:10.18863/pgy.281117 · Cited by 15
Methylphenidate and emotional-motivational processing in attention-deficit/hyperactivity disorder
Conzelmann, A., Woidich, E., Mucha, R. F., Weyers, P., Müller, M., Lesch, K., Jacob, C., & Pauli, P. (2016) · Journal of Neural Transmission · doi:10.1007/s00702-016-1512-y · Cited by 10
Pharmacologic and non-pharmacologic interventions for emotional lability: A meta-analysis
Agapoff, J. R., Zhang, C., Meek, M., & van Schalkwyk, G. I. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105184 · Cited by 9
ADHD and Nicotine Use in Schizophrenia or Asperger Syndrome
Hallerbäck, M. U., Lugnegård, T., & Gillberg, C. (2012) · Journal of Attention Disorders · doi:10.1177/1087054712439099 · Cited by 9
Desregulación emocional en población con TDAH; una aproximación teórica/Emotional dysregulation in the population with ADHD. A Theoretical Approach
Alpizar, A. (2019) · Revista Costarricense de Psicología · doi:10.22544/rcps.v38i01.02 · Cited by 8
Influence of Substance Use Disorder on Treatment Retention of Adult-Attention-Deficit/Hyperactive Disorder Patients. A 5-Year Follow-Up Study
Pallucchini, A., Carli, M., Maremmani, A. G. I., Scarselli, M., Perugi, G., & Maremmani, I. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10091984 · Cited by 9
Drug Class Review: Pharmacologic Treatments for Attention Deficit Hyperactivity Disorder
McDonagh, M. S., & Peterson, K. (2011) · Cited by 7
Emotional dysregulation and stimulant medication in adult ADHD
Greenfield, M. S., Wang, Y., Hamilton, J. P., Thunberg, P., & Msghina, M. (2024) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.240009 · Cited by 10
Do ADHD Treatments Improve Executive Behavior Beyond Core ADHD Symptoms in Adults? Evidence From Systematic Analysis of Clinical Trials
Surman, C. B. H., & Walsh, D. M. (2023) · The Journal of Clinical Pharmacology · doi:10.1002/jcph.2209 · Cited by 8
College students with ADHD
Ramsay, J. R., & Rostain, A. L. (2014) · Cambridge University Press eBooks · doi:10.1017/cbo9781139035491.030 · Cited by 6
Do Treatments for Adult ADHD Improve Emotional Behavior? A Systematic Review and Analysis
Surman, C. B. H., & Walsh, D. M. (2022) · Journal of Attention Disorders · doi:10.1177/10870547221110926 · Cited by 6
Medikamentöse Therapie der Aufmerksamkeitsdefizit‑/Hyperaktivitätsstörung im Erwachsenenalter
Retz, W., Retz‐Junginger, P., Davydenko, S., & Rösler, M. (2020) · Der Nervenarzt · doi:10.1007/s00115-020-00891-3 · Cited by 5
Dikkat Eksikliği ve Hiperaktivite Bozukluğunda Duygu Düzenleme Güçlükleri ve Tedavisi
Öztürk, Y., Özyurt, G., Tufan, A. E., & Pekcanlar, A. A. (2017) · Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry · doi:10.18863/pgy.358101 · Cited by 9
ADHD in Adults: A Clinical Concern
Asherson, P. J. (2012) · Humana Press eBooks · doi:10.1007/978-1-62703-248-3_1 · Cited by 7
Managing ADHD in Adults with Common Comorbidities
Sobanski, E., Paslakis, G., Schredl, M., Daffner, S., & Alm, B. (2012) · Humana Press eBooks · doi:10.1007/978-1-62703-248-3_8 · Cited by 6
Trouble déficit d’attention/hyperactivité (TDA/H) et émotions : de la labilité émotionnelle au trouble bipolaire
Purper‐Ouakil, D., Vacher, C., & Villemonteix, T. (2014) · Annales Médico-psychologiques revue psychiatrique · doi:10.1016/j.amp.2014.03.004 · Cited by 4
Effectiveness of Pharmacological Treatments for Adult ADHD on Psychiatric Comorbidity: A Systematic Review
Tripodi, B., Carbone, M. G., Matarese, I., Rizzato, R., Rocca, F. D., Dominicis, F. D., & Callegari, C. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14248848 · Cited by 4
OROS-methylphenidate to reduce ADHD symptoms in male prisoners aged 16–25 years: a RCT
Asherson, P. J., Johansson, L., Holland, R., Bedding, M., Forrester, A., Giannulli, L., Ginsberg, Y., Howitt, S., Kretzschmar, I., Lawrie, S. M., et al. (2022) · Efficacy and Mechanism Evaluation · doi:10.3310/thei8200 · Cited by 4
Exploring the efficacy of dialectical behaviour therapy and methylphenidate on emotional comorbid symptoms in adults with attention Deficit/Hyperactivity disorder: Results of the COMPAS multicentre randomised controlled trial
López-Pinar, C., Selaskowski, B., Braun, N., Fornés, V., Euscher, R., Matthies, S., Jans, T., van Elst, L. T., Jacob, C., Huß, M., et al. (2023) · Psychiatry Research · doi:10.1016/j.psychres.2023.115610 · Cited by 4
Emotionsregulation
Riechmann, E., Sattler, F. A., Christiansen, H., & Chavanon, M. (2017) · Lernen und Lernstörungen · doi:10.1024/2235-0977/a000178 · Cited by 3
A Conceptual Review on ADHD and Adult ADHD (2): Psychopathology, Diagnostic and Therapeutic Implications of ADHD
An, Y., Song, Y., & Kang, U. G. (2022) · 신경정신의학 · doi:10.4306/jknpa.2022.61.2.45 · Cited by 3

Authors: Rösler, M., Retz, W., Fischer, R., Ose, C., Alm, B., Deckert, J., Philipsen, A., Herpertz, S., & Ammer, R.
Affiliations: Universitätsklinikum des Saarlandes (DE)
Medice (Germany) (DE)
Institut für Medizinische Informatik, Biometrie und Epidemiologie (DE)
Central Institute of Mental Health (DE)
University of Würzburg (DE)
University of Freiburg (DE)
University of Rostock (DE)
Corresponding author: Rösler, Michael
ORCID: Rösler, Michael
Retz, Wolfgang
Ose, Claudia
Deckert, Jürgen
Philipsen, Alexandra
Herpertz, Sabine
Ammer, Richard
Venue: The World Journal of Biological Psychiatry
Publisher: Informa UK Limited
Published: 2010-03-30
Volume: 11
Issue: 5
Pages: 709-718
ISSN: 1562-2975 (ISSN-L)
1814-1412
DOI: 10.3109/15622971003624197
OpenAlex: W1985528539
Cited by: 131
References: 43
Citations by year: 2026: 3 · 2025: 4 · 2024: 1 · 2023: 6 · 2022: 8 · 2021: 7 · 2020: 8 · 2019: 7 · 2018: 6 · 2017: 11 · 2016: 13 · 2015: 11 · 2014: 20 · 2013: 7 · 2012: 9
FWCI: 5.67
Type: journal article
Language: en
Open access: closed
Locations: The World Journal of Biological Psychiatry (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords: adult ADHD, extended-release methylphenidate, emotional symptoms, emotional dysregulation, emotional lability, obsessive-compulsive symptoms, self-concept, long-term treatment efficacy, comorbid psychopathology
MeSH terms: Adult, Central Nervous System Stimulants, Attention Deficit Disorder with Hyperactivity, Delayed-Action Preparations, Double-Blind Method, Emotions, Female, Follow-Up Studies, Humans, Long-Term Care, Male, Methylphenidate, Middle Aged, Obsessive-Compulsive Disorder, Personality Assessment, Psychometrics, Treatment Outcome, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Twenty-four-week treatment with extended release methylphenidate improves emotional symptoms in adult ADHD

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks