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Maternal Depressive Symptomatology: 16-Month Follow-up of Infant and Maternal Health-Related Quality of Life
Open accessAbstract
PURPOSE: The purpose of this study was to document risk factors for depressive symptoms during the postpartum period among working mothers and to determine longitudinal effects of depressive symptoms on maternal health-related quality of life and infant health and development. METHODS: Mother-infant dyads from a community-based cohort study of working mothers were recruited when infants were 4 months old and were interviewed every 4 months until infants were 16 months old. Depressive symptoms and health-related quality of life were assessed using the Center for Epidemiologic Studies Depression Scale and the Short Form-12 Health Survey, respectively. Infant development and health-related quality of life were measured with the Ages and Stages Questionnaire and the Infant-Toddler Quality of Life Questionnaire, respectively. RESULTS: Depressive symptoms were elevated among mothers who were younger, less educated, African American, unmarried, and impoverished. Mothers with significant depressive symptoms had significantly poorer physical and mental health-related quality of life, reported greater pain for their infant, and had more health-related concerns about their child. Maternal depressive symptoms at 4 months predicted infant poorer health-related quality of life at 8, 12, and 16 months. CONCLUSIONS: Several characteristics, including age, education level, race, marital status, and poverty, can help primary care physicians identify working mothers at risk for depressive symptoms. Identification of these symptoms is important; they are correlated with poorer maternal health-related quality of life and they predict poorer children's health-related quality of life.
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“Women with PPD had lower scores on all dimensions of quality of life (e.g. SF-36 or a generic Health-Related Quality of Life (HRQoL) questionnaire) than women without PPD.”
From Consequences of maternal postpartum depression: A systematic review of maternal and infant outcomes (2019) · cites this paper as [48]
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“Two studies reported greater overall pain in the infants of depressed mothers48 and a stronger infant pain response during routine vaccinations.123”
From Consequences of maternal postpartum depression: A systematic review of maternal and infant outcomes (2019) · cites this paper as [48]
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“Three studies48,86,88 demonstrated a significantly negative association between maternal depressive symptoms and quality of life.”
From Consequences of maternal postpartum depression: A systematic review of maternal and infant outcomes (2019) · cites this paper as [48]
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“Mothers with significant depressive symptoms had significantly worse physical (p = 0.02) and mental (< 0.0001) health-related quality of life.”
From Consequences of maternal postpartum depression: A systematic review of maternal and infant outcomes (2019) · cites this paper as [48]
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“However, one of the three studies showed that after controlling for mental health-related quality of life earlier in the postpartum period, there was no difference in the subsequent mental health-related quality of life according to the presence of significant depressive symptoms later in the postpartum period.48”
From Consequences of maternal postpartum depression: A systematic review of maternal and infant outcomes (2019) · cites this paper as [48]
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“One study demonstrated that maternal PPD at 4 months predicted worse health-related quality of life for the infant in the following months.48”
From Consequences of maternal postpartum depression: A systematic review of maternal and infant outcomes (2019) · cites this paper as [48]
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Consequences of maternal postpartum depression: A systematic review of maternal and infant outcomes
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A Systematic Review of Quality of Life Measures in Pregnant and Postpartum Mothers
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Metadata
- Authors
- Darcy, J. M., Grzywacz, J. G., Stephens, R. L., Leng, I., Clinch, C. R., & Arcury, T. A.
- Affiliations
- Wake Forest University Health Sciences (US)
- Corresponding author
- Grzywacz, J. G.
- Venue
- The Journal of the American Board of Family Medicine
- Published
- 2011-05-01
- Volume
- 24
- Issue
- 3
- Pages
- 249-257
- ISSN
- 1557-2625 (ISSN-L)
- 1558-7118
- PMC
- PMC3114440
- OpenAlex
- W2044852839
- Cited by
- 119
- References
- 41
- Citations by year
- 2026: 5 · 2025: 10 · 2024: 10 · 2023: 8 · 2022: 8 · 2021: 11 · 2020: 7 · 2019: 13 · 2018: 9 · 2017: 6 · 2016: 5 · 2015: 9 · 2014: 3 · 2013: 6 · 2012: 6
- FWCI
- 5.66
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Journal of the American Board of Family Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R21HD048601, HD48601)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Maternal and Neonatal Healthcare
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- maternal depressive symptoms, postpartum depression, working mothers, health-related quality of life, infant development, risk factors, poverty, marital status, race, educational attainment, infant pain
- MeSH terms
- Adolescent, Adult, Cross-Sectional Studies, Female, Health Status, Health Surveys, Humans, Infant, Infant Welfare, Infant, Newborn, Maternal Welfare, Mother-Child Relations, Pregnancy, Prospective Studies, Psychometrics, Quality of Life, Surveys and Questionnaires, Risk Factors, Time Factors, Multivariate Analysis, Chi-Square Distribution, Depression, Postpartum, Young Adult
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