Donor Hemovigilance Programme in managing Blood Transfusion Needs: Complications of Whole Blood Donation
Open accessAbstract
Background: Hemovigilance like quality systems and audits have become an integral part of Blood Transfusion Services in the developed countries and has contributed greatly to its development. Hemovigilance begins with donors and must enable the collection of information on reactions occurring during the donation of blood, selections of donors and to prevent such incidents. The aim of study was to help identify the trends of adverse events , occurring in blood donors at a tertiary-care hospital, to recommend best practices to improve donor care and safety Materials and Methods: This record-based study was conducted on all adverse events related to allogenic whole blood donations performed over 24 months. All whole blood donations were analyzed. All adverse events occurring during or at the end of the donation were noted using a standardized format and analyzed determining significance at p<0.05. Results: Overall rate was 0.3% with vasovagal reactions constituting 82%, and 18% mild syncopal reactions (p<0.001). Immediate vasovagal reaction with injury was very rare (0.007%). Vasovagal reactions showed a significant association with young age, female gender, first time donation status. Mean age of persons recording adverse effects was 30.23 ± 7.49 years as compared to those without adverse effects, 31.14 ± 8.56 years. Conclusion: Donor safety is an essential perquisite to increase voluntary blood donation. AE analysis helps in identifying the blood donors at risk of AE, applying appropriate motivational strategies, predonation counseling, care during and after donation, developing guidelines and hemovigilance programme in countries with limited resources. DOI: http://dx.doi.org/10.3126/jpn.v3i6.8993 Journal of Pathology of Nepal (2013) Vol. 3, 459-463
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Many studies have reported higher prevalence of vasovagal reactions among female donors in various donation setups.
“Many studies have reported higher prevalence of vasovagal reactions among the female donors in various donation setup (4,9,16,17,22,23, 24, 25, 26).”
From ADVERSE EVENTS IN BLOOD DONORS: SPECTRUM AND REMEDY (2023) · cites this paper as [26]
Cites
Newman, B. H., Pichette, S., Pichette, D., & Dzaka, E. (2003) · Transfusion · doi:10.1046/j.1537-2995.2003.00368.x · Cited by 186 · see citing works
Wiltbank, T. B., Giordano, G. F., Kamel, H., Tomasulo, P., & Custer, B. (2008) · Transfusion · doi:10.1111/j.1537-2995.2008.01745.x · Cited by 149 · see citing works
The American Red Cross donor hemovigilance program: complications of blood donation reported in 2006
Eder, A. F., Dy, B. A., Kennedy, J. M., Notari IV, E. P., Strupp, A., Wissel, M. E., Reddy, R., Gibble, J., Haimowitz, M. D., Newman, B. H., et al. (2008) · Transfusion · doi:10.1111/j.1537-2995.2008.01811.x · Cited by 149 · see citing works
Adverse reactions in blood and apheresis donors: experience from two Italian transfusion centres.
(2009) · PubMed Central · doi:10.2450/2008.0018-08 · Cited by 69 · see citing works
Marwaha, N., Agnihotri, N., & Sharma, R. (2012) · Asian Journal of Transfusion Science · doi:10.4103/0973-6247.98922 · Cited by 62 · see citing works
Complications related to blood donation: a population‐based study
Sørensen, B. S., Johnsen, S. P., & Jørgensen, J. O. L. (2007) · Vox Sanguinis · doi:10.1111/j.1423-0410.2007.01000.x · Cited by 56 · see citing works
Vasovagal reactions in whole blood donors at three REDS‐II blood centers in Brazil
Gonçalez, T. T., Sabino, É. C., Schlumpf, K. S., Wright, D. J., Leão, S. C., Sampaio, D., Takecian, P. L., Proitetti, A. B., Murphy, E. L., Busch, M. P., et al. (2011) · Transfusion · doi:10.1111/j.1537-2995.2011.03432.x · Cited by 43 · see citing works
Hemovigilance and blood safety
Jain, A., & Kaur, R. (2012) · Asian Journal of Transfusion Science · doi:10.4103/0973-6247.98911 · Cited by 39 · see citing works
Adverse reactions in whole blood donors: an Indian scenario.
(2011) · Europe PMC (PubMed Central) · doi:10.2450/2010.0002-10 · Cited by 34 · see citing works
Hemovigilance in developing countries
Ayob, Y. (2010) · Biologicals · doi:10.1016/j.biologicals.2009.10.002 · Cited by 24 · see citing works
Baroreflex sensitivity during noxious stimulation in vasovagal reactors to blood donation
France, C. R. (1995) · International Journal of Psychophysiology · doi:10.1016/0167-8760(94)00058-m · Cited by 21 · see citing works
Adverse reactions to blood donations: the READ project.
(2010) · PubMed Central · doi:10.2450/2009.0089-09 · Cited by 20 · see citing works
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Tiwari, A. K., Aggarwal, G., Dara, R., Arora, D., Srivastava, K., & Raina, V. (2016) · Transfusion and Apheresis Science · doi:10.1016/j.transci.2016.10.009 · Cited by 13 · see citing works
Navkudkar, A., Desai, P., & Rajadhakshaya, S. (2021) · Indian Journal of Medical Sciences · doi:10.25259/ijms_499_2020 · Cited by 2 · see citing works
ADVERSE EVENTS IN BLOOD DONORS: SPECTRUM AND REMEDY
Bhushan, R., Gupta, P., Mehra, A., & Iyengar, S. (2023) · PARIPEX-Indian Journal of Research · doi:10.36106/paripex/1800303
Addae, R. N. F., Sobre, P., Mumin, I. A., Siaw, A. S., Quansah, N. P., Asmah-Brown, A., Awittor, P. J., Boachie, J., & Adu, P. (2025) · Advances in Hematology · doi:10.1155/ah/3668746
“It is worth noting that developing countries still struggle to attract and retain blood donors or to ensure a sufcient and safe blood supply [11, 12].”
- Authors
- Mangwana, S.
- Corresponding author
- Mangwana, S
- Venue
- Journal of Pathology of Nepal
- Publisher
- Nepal Journals Online (JOL)
- Published
- 2013-10-24
- Volume
- 3
- Issue
- 6
- Pages
- 459-463
- ISSN
- 2091-0797 (ISSN-L)
- 2091-0908
- OpenAlex
- W2092113469
- Cited by
- 4
- References
- 12
- Citations by year
- 2025: 1 · 2023: 1 · 2021: 1 · 2016: 1
- FWCI
- 0.73
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by
- Locations
- Journal of Pathology of Nepal (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Social Sciences › Business, Management and Accounting › Management of Technology and Innovation › Blood donation and transfusion practices
- Health Sciences › Medicine › Biochemistry › Blood transfusion and management
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Organ Donation and Transplantation
- Keywords
- hemovigilance, whole blood donation, adverse events, vasovagal reaction, syncope, donor safety, blood donor selection, voluntary blood donation, risk factors
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