Endoscopic-assisted repair of craniosynostosis
Open accessAbstract
OBJECT: The goal of the craniofacial surgeon has always been the correction of form and function with prevention of associated morbidity and death. Through the pioneering work of Jimenez and Barone, minimally invasive approaches to the surgical correction of craniosynostosis are now gaining wider acceptance. Here the authors review the technique for endoscopic-assisted repair of craniosynostosis from the perspective of a new minimally invasive approach. They also assess the safety, efficacy, and results of the early treatment of infants with craniosynostosis in a small series of children who underwent surgery at this institution. METHODS: Data regarding synostosis type, operative time, patient age, blood loss, transfusion rates, duration of hospitalization, and complications were collected. Nineteen patients (12 girls and seven boys) between the ages of 1.2 and 5 months of age were treated with the endoscope-assisted technique. The mean operative time was 97 minutes. Five (26%) of 19 children received a blood transfusion. Most patients were discharged home the morning after surgery. The clinical courses of two patients who required additional major craniofacial reconstructions are discussed. There were no deaths, dural sinus tears, cerebrospinal fluid leaks, neurological injuries, or infections, and there were no complications related to the use of helmet therapy. Seventeen of the 19 patients achieved excellent cosmetic results with a single surgery. CONCLUSIONS: This small series supports larger experiences and indicates that early treatment of craniosynostosis with minimally invasive, endoscope-assisted techniques is safe; limits blood transfusion, hospital stay, and operative time; and represents a valuable alternative to the traditional calvarial reconstruction methods.
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Endoscopic treatment is based on the ability of the developing brain to reshape the skull, and the corrective helmet provides support by inhibiting the longitudinal growth vector and stimulating the lateral growth vector.
“Endoscopic treatment is based on the ability of the developing brain to reshape the skull, and the corrective helmet provides adequate support by inhibiting the longitudinal growth vector of the skull and thereby stimulating the lateral growth vector [71,72].”
From Isolated Sagittal Craniosynostosis: A Comprehensive Review (2024) · cites this paper as [72]
The Introduction describes skull growth being restricted by a fused suture, and Posthospital Care and Cranial Orthoses describes postoperative helmets used during head growth. The Conclusions call helmet therapy important to good results. Our copy does not state that the developing brain reshapes the skull or that the helmet inhibits longitudinal growth and stimulates lateral growth. (LLM, conf=0.82)
Experimental — accuracy not yet measuredSeveral studies have shown the efficacy of endoscopic treatment of ISS and comparable results to those after open cranial remodelling.
“Several studies have shown the efficacy of endoscopic treatment of ISS and comparable results to those after open cranial remodelling [71,72,73].”
From Isolated Sagittal Craniosynostosis: A Comprehensive Review (2024) · cites this paper as [72]
The Results (page not provided) report good cosmetic results after endoscopic treatment in 17 of 19 infants, including 11 with isolated sagittal synostosis. The Discussion describes excellent long-term cosmetic outcomes after open procedures, but the paper does not establish that the two approaches have comparable results. (LLM, conf=0.84)
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“Endoscopic treatment is based on the ability of the developing brain to reshape the skull, and the corrective helmet provides adequate support by inhibiting the longitudinal growth vector of the skull and thereby stimulating the lateral growth vector [71,72].”
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Moderne Behandlung von Kraniosynostosen
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- Authors
- Murad, G. J. A., Clayman, M., Seagle, M. B., White, S., Perkins, L. A., & Pincus, D. W.
- Affiliations
- University of Florida Health (US)
- ORCID
- Murad, Gregory J. A.
- Venue
- Neurosurgical FOCUS
- Published
- 2005-12
- Volume
- 19
- Issue
- 6
- Pages
- 1-10
- ISSN
- 1092-0684 (ISSN-L)
- OpenAlex
- W1999995461
- Cited by
- 160
- References
- 23
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 1 · 2023: 2 · 2022: 4 · 2021: 4 · 2020: 4 · 2019: 77 · 2018: 7 · 2017: 5 · 2016: 4 · 2015: 5 · 2014: 8 · 2013: 6 · 2012: 6
- FWCI
- 0.90
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Neurosurgical FOCUS (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Craniofacial Disorders and Treatments
- Health Sciences › Medicine › Surgery › Reconstructive Facial Surgery Techniques
- Health Sciences › Medicine › Surgery › Pectus Deformity Diagnosis and Treatment
- Keywords
- craniosynostosis, endoscopic-assisted surgery, infants, surgical outcomes, blood transfusion, operative time, craniofacial reconstruction, helmet therapy
- MeSH terms
- Age Factors, Blood Transfusion, Cerebrospinal Fluid Rhinorrhea, Craniosynostoses, Endoscopy, Facial Bones, Female, Head Protective Devices, Humans, Infant, Length of Stay, Male, Postoperative Complications, Skull, Treatment Outcome, Postoperative Hemorrhage, Neurosurgical Procedures, Plastic Surgery Procedures
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