The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Pain reduction by electrical brain stimulation in man: Part 1: Acute administration in periaqueductal and periventricular sites
Abstract
✓ Acute studies performed in five patients indicate that electrical stimulation of the brain could be a powerful tool for the reduction or control of intractable pain. While chronic or spontaneous pain could be relieved by stimulation of the periaqueductal gray matter, the accompanying side effects render it impossible to stimulate this site regularly. On the other hand, stimulation of medial thalamic sites, particularly medial to the nucleus parafascicularis, yielded good relief of chronic pain at parameters which did not cause many undesirable side effects. The same parameters also produced inhibition of acute pain in two of the five patients.
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Citations
Cites
Surgery in the Rat during Electrical Analgesia Induced by Focal Brain Stimulation
Reynolds, D. V. (1969) · Science · doi:10.1126/science.164.3878.444 · Cited by 1,389
Electrical inhibition of pain by stimulation of the dorsal columns: preliminary clinical report.
Shealy, C. N., Mortimer, J. T., & RESWICK, J. B. (1990) · PubMed · Cited by 1,237
Analgesia from Electrical Stimulation in the Brainstem of the Rat
Mayer, D. J., Wolfle, T. L., Akil, H., Carder, B., & Liebeskind, J. C. (1971) · Science · doi:10.1126/science.174.4016.1351 · Cited by 772
Self-citationPain reduction by focal electrical stimulation of the brain: An anatomical and behavioral analysis
Mayer, D. J., & Liebeskind, J. C. (1974) · Brain Research · doi:10.1016/0006-8993(74)90534-4 · Cited by 719
Sensations Evoked by Stimulation in the Midbrain of Man
Nashold, B. S., Wilson, W. P., & Slaughter, D. G. (1969) · Journal of Neurosurgery · doi:10.3171/jns.1969.30.1.0014 · Cited by 549
Richardson, D. E., & Akil, H. (1977) · Journal of Neurosurgery · doi:10.3171/jns.1977.47.2.0184 · Cited by 443
Self-citationLiebeskind, J. C., Guilbaud, G., Besson, J.-M., & Oliveras, J.-L. (1973) · Brain Research · doi:10.1016/0006-8993(73)90748-8 · Cited by 439
Monoaminergic mechanisms of stimulation-produced analgesia
Akil, H., & Liebeskind, J. C. (1975) · Brain Research · doi:10.1016/0006-8993(75)90062-1 · Cited by 345
Self-citationAntagonism of stimulation-produced analgesia by p-CPA, a serotonin synthesis inhibitor
Akil, H., & Mayer, D. J. (1972) · Brain Research · doi:10.1016/0006-8993(72)90338-1 · Cited by 286
Self-citationMesencephalic central gray lesions and fear-motivated behavior in rats
Liebman, J. M., Mayer, D. J., & Liebeskind, J. C. (1970) · Brain Research · doi:10.1016/0006-8993(70)90062-4 · Cited by 241
Cited by
Ossipov, M. H., Dussor, G. O., & Porreca, F. (2010) · Journal of Clinical Investigation · doi:10.1172/jci43766 · Cited by 1,159
Translational principles of deep brain stimulation
Kringelbach, M. L., Jenkinson, N., Owen, S. L. F., & Aziz, T. Z. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2196 · Cited by 853
Descending pain modulation and chronification of pain
Ossipov, M. H., Morimura, K., & Porreca, F. (2014) · Current Opinion in Supportive & Palliative Care · doi:10.1097/spc.0000000000000055 · Cited by 815
Hosobuchi, Y., Adams, J. E., & Linchitz, R. (1977) · Science · doi:10.1126/science.301658 · Cited by 757
Probing and regulating dysfunctional circuits using deep brain stimulation
Lozano, A. M., & Lipsman, N. (2013) · Neuron · doi:10.1016/j.neuron.2013.01.020 · Cited by 665
Metadata
- Authors
- Richardson, D. E., & Akil, H.
- Venue
- Journal of Neurosurgery
- Published
- 1977-08
- Volume
- 47
- Issue
- 2
- Pages
- 178-183
- ISSN
- 0022-3085 (ISSN-L)
- OpenAlex
- W2789756371
- Cited by
- 441
- References
- 12
- FWCI
- 25.44
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Pain reduction by electrical brain stimulation in man: Part 1: Acute administration in periaqueductal and periventricular sites. https://app.cochat.ai/papers/10.3171/jns.1977.47.2.0178
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- Richardson, D. E., & Akil, H. (1977). Pain reduction by electrical brain stimulation in man: Part 1: Acute administration in periaqueductal and periventricular sites. Journal of Neurosurgery. https://doi.org/10.3171/jns.1977.47.2.0178
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
