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Functional neuroimaging studies of the effects of psychotherapy.
Open accessAbstract
It has been long established that psychological interventions can markedly alter patients' thinking patterns, beliefs, attitudes, emotional states, and behaviors. Little was known about the neural mechanisms mediating such alterations before the advent of functional neuroimaging techniques. Since the turn of the new millenium, several functional neuroimaging studies have been conducted to tackle this important issue. Some of these studies have explored the neural impact of various forms of psychotherapy in individuals with major depressive disorder. Other neuroimaging studies have investigated the effects of psychological interventions for anxiety disorders. I review these studies in the present article, and discuss the putative neural mechanisms of change in psychotherapy. The findings of these studies suggest that mental and behavioral changes occurring during psychotherapeutic interventions can lead to a normalization of functional brain activity at a global level.
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“This is a fundamentally new perspective because psychotherapy research to date has only considered the patient’s brain as the locus of therapeutic effects (Etkin et al., 2005; Beauregard, 2014; Weingarten and Strauman, 2015).”
From Synchrony in Psychotherapy: A Review and an Integrative Framework for the Therapeutic Alliance (2016) · cites this paper as Beauregard, 2014
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Cites
Ongur, D. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.3.206 · Cited by 2,627
Neurobiology of emotion perception II: implications for major psychiatric disorders
Phillips, M. L., Drevets, W. C., Rauch, S. L., & Lane, R. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00171-9 · Cited by 1,736
Limbic connections of the orbital and medial prefrontal cortex in macaque monkeys
Carmichael, S. T., & Price, J. L. (1995) · Journal of Comparative Neurology · doi:10.1002/cne.903630408 · Cited by 1,197
Sheline, Y. I., Barch, D. M., Donnelly, J. M., Ollinger, J. M., Snyder, A. Z., & Mintun, M. A. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01263-x · Cited by 1,191
Goldapple, K., Segal, Z., Garson, C., Lau, M., Bieling, P., Kennedy, S., & Mayberg, H. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.1.34 · Cited by 1,068
Architectonic subdivision of the human orbital and medial prefrontal cortex
Öngür, D., Ferry, A. T., & Price, J. L. (2003) · Journal of Comparative Neurology · doi:10.1002/cne.10609 · Cited by 944
Fu, C. H. Y., Williams, S. C. R., Cleare, A. J., Brammer, M. J., Walsh, N. D., Kim, J., Andrew, C. M., Pich, E. M., Williams, P. M., Reed, L. J., et al. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.9.877 · Cited by 775
Neuroanatomical correlates of happiness, sadness, and disgust
Lane, R. D., Reiman, E. M., Ahern, G. L., SCHWARTZ, G. E. R., & Davidson, R. J. (1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.7.926 · Cited by 756
Neuroanatomical correlates of externally and internally generated human emotion
(1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.7.918 · Cited by 711
Schwartz, J. M. (1996) · Archives of General Psychiatry · doi:10.1001/archpsyc.1996.01830020023004 · Cited by 694
Functional anatomical abnormalities in limbic and prefrontal cortical structures in major depression
Drevets, W. C. (2000) · Progress in Brain Research · doi:10.1016/s0079-6123(00)26027-5 · Cited by 659
Targeted electrode-based modulation of neural circuits for depression.
Mayberg, H. S. (2009) · Journal of Clinical Investigation · doi:10.1172/jci38454 · Cited by 542
Furmark, T., Tillfors, M., Marteinsdottir, I., Fischer, H., Pissiota, A., Långström, B., & Fredrikson, M. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.5.425 · Cited by 530
Evidence for Abnormal Cortical Functional Connectivity During Working Memory in Schizophrenia
Meyer‐Lindenberg, A., Poline, J., Kohn, P. D., Holt, J. L., Egan, M. F., Weinberger, D. R., & Berman, K. F. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.11.1809 · Cited by 511
How psychotherapy changes the brain – the contribution of functional neuroimaging
Linden, D. E. J. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001816 · Cited by 491
The neural substrates of affective processing in depressed patients treated with venlafaxine
Davidson, R. J., Irwin, W., Anderle, M. J., & Kalin, N. H. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.1.64 · Cited by 487
Paquette, V., Lévesque, J., Mensour, B., Leroux, J.-M., Beaudoin, G., Bourgouin, P., & Beauregard, M. (2003) · NeuroImage · doi:10.1016/s1053-8119(02)00030-7 · Cited by 452
Self-citationThe Neural Basis of Mood-Congruent Processing Biases in Depression
Elliott, R., Rubinsztein, J. S., Sahakian, B. J., & Dolan, R. J. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.7.597 · Cited by 440
Kennedy, S. H., Konarski, J. Z., Segal, Z. V., Lau, M. A., Bieling, P. J., McIntyre, R. S., & Mayberg, H. S. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.5.778 · Cited by 420
Martin, S. D., Martin, E., Rai, S. S., Richardson, M. A., & Royall, R. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.7.641 · Cited by 324
Functional MRI Study of the Cognitive Generation of Affect
Teasdale, J. D., Howard, R. J., Cox, S. G., Ha, Y., Brammer, M. J., Williams, S., & Checkley, S. A. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.2.209 · Cited by 288
Neuroimaging and the functional neuroanatomy of psychotherapy
Roffman, J. L., Marci, C. D., Glick, D. M., Dougherty, D. D., & Rauch, S. L. (2005) · Psychological Medicine · doi:10.1017/s0033291705005064 · Cited by 288
Ablon, J. S., & Jones, E. E. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.5.775 · Cited by 280
Effects of cognitive-behavioral therapy on brain activation in specific phobia
Straube, T., Glauer, M., Dilger, S., Mentzel, H.-J., & Miltner, W. H. R. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.07.007 · Cited by 264
Toward a neurobiology of psychotherapy: basic science and clinical applications
Etkin, A., Pittenger, C., Polan, H. J., & Kandel, E. R. (2005) · The Journal of Neuropsychiatry and Clinical Neurosciences · doi:10.1176/jnp.17.2.145 · Cited by 244
Changes in Prefrontal-Limbic Function in Major Depression after 15 Months of Long-Term Psychotherapy
Buchheim, A., Viviani, R., Kessler, H., Kächele, H. U., Cierpka, M., Roth, G., George, C. C., Kernberg, O. F., Bruns, G. J., & Taubner, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033745 · Cited by 237
Symptom provocation and reduction in patients suffering from spider phobia
Schienle, A., Schäfer, A., Hermann, A., Rohrmann, S., & Vaitl, D. (2007) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-007-0754-y · Cited by 154
境, 洋., Kumano, H., Nishikawa, M., Sakano, Y., Kaiya, H., Imabayashi, E., Ohnishi, T., Matsuda, H., Yasuda, A., Sato, A., et al. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.06.017 · Cited by 140
Dichter, G. S., Felder, J. N., & Smoski, M. J. (2010) · Journal of Affective Disorders · doi:10.1016/j.jad.2010.03.022 · Cited by 139
Lindauer, R. J. L., Booij, J., Habraken, J. B. A., van Meijel, E. P. M., Uylings, H. B. M., Olff, M., Carlier, I. V. E., den Heeten, G. J., van Eck-Smit, B. L. F., & Gersons, B. P. R. (2008) · Psychological Medicine · doi:10.1017/s0033291707001432 · Cited by 131
Praško, J. P., Horáček, J., Záleský, R., Kopeček, M., Novák, T., Paskova, B., Skrdlantová, L., Bělohlávek, O., & Höschl, C. (2004) · PubMed · Cited by 130
Klumpp, H., Fitzgerald, D. A., & Phan, K. L. (2013) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2013.05.004 · Cited by 126
Lehto, S. M., Tolmunen, T., Joensuu, M., Saarinen, P., Valkonen‐Korhonen, M., Vanninen, R. L., Ahola, P., Tiihonen, J., Kuikka, J. T., & Lehtonen, J. (2007) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2007.08.013 · Cited by 102
Wang, T., Huang, X., Huang, P., Li, D., Lv, F., Zhang, Y., Zhou, L., Yang, D., & Xie, P. (2013) · PLoS ONE · doi:10.1371/journal.pone.0063081 · Cited by 40
PSYCHOTHERAPY RESEARCH AND NEUROBIOLOGY: CHALLENGE, CHANCE, OR ENRICHMENT?
Caspar, F. (2003) · Psychotherapy Research · doi:10.1093/ptr/kpg013 · Cited by 17
Functional neuroimaging: points of intersection between biology and psychotherapy.
Marano, G., Traversi, G., Nannarelli, C., Pitrelli, S., Mazza, S., & Mazza, M. (2012) · PubMed · Cited by 7
Brody, A. L., Saxena, S., Stoessel, P., Gillies, L. A., Fairbanks, L. A., Alborzian, S., Phelps, M. E., Huang, S.-C., Wu, H.-M., Ho, M. L., et al. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.7.631 · Cited by 5
Research works printed but not linked: 6
- Marano G., 2012, Clin Ter., 163, e443
- Schwartz JM., 2002, The Mind and the Brain: Neuroplasticity and the Power of Mental Force. New York, NY: Harper Collins (Regan Books);
- Nyanaponika T., 2000, The Vision of Dhamma: Buddhist Writings of Nyanaponika Thera. Seattle, WA: BPS Pariyatti Editions;
- Prasko J., 2004, Neuro Endocrinol Lett., 25, 340
- Beck AT., 2005, Anxiety Disorders and Phobias: a Cognitive Perspective. New York, NY: Basic Books;
- Beaulieu C., 2009, Diffusion MRI: From Quantitative Measurement to in Vivo Neuroanatomy. London, UK: Elsevier, 105
Cited by
Sorted by citations
Synchrony in Psychotherapy: A Review and an Integrative Framework for the Therapeutic Alliance
Koole, S. L., & Tschacher, W. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.00862 · Cited by 456
“These two modes of behaving in synchrony (Beauregard, 2014) could have differential effects in psychotherapy, but this remains to be investigated in future research.”
BackgroundThe Neurobiological Underpinnings of Psychoanalytic Theory and Therapy
Solms, M. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00294 · Cited by 174
Updated report on tools to measure outcomes of clinical trials in fragile X syndrome
Budimirovic, D. B., Berry‐Kravis, E., Erickson, C. A., Hall, S. S., Hessl, D. R., Reiss, A. L., King, M. K., Abbeduto, L., & Kaufmann, W. E. (2017) · Journal of Neurodevelopmental Disorders · doi:10.1186/s11689-017-9193-x · Cited by 159
Clinical and neural responses to cognitive behavioral therapy for functional tremor
Espay, A. J., Ries, S., Maloney, T., Vannest, J. J., Neefus, E., Dwivedi, A. K., Allendorfer, J. B., Wulsin, L. R., LaFrance, W. C., Jr., Lang, A. E., et al. (2019) · Neurology · doi:10.1212/wnl.0000000000008442 · Cited by 106
A perfect match: noninvasive brain stimulation and psychotherapy
Bajbouj, M., & Padberg, F. (2014) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-014-0540-6 · Cited by 72
Metadata
- Authors
- Beauregard, M.
- Affiliations
- University of Arizona (US)
- Corresponding author
- Beauregard, Mario
- Venue
- Dialogues in Clinical Neuroscience
- Publisher
- Informa UK Limited
- Published
- 2014-03-31
- Volume
- 16
- Issue
- 1
- Pages
- 75-81
- ISSN
- 1294-8322 (ISSN-L)
- 1958-5969
- PMC
- PMC3984893
- OpenAlex
- W1496288922
- Cited by
- 110
- References
- 37
- Citations by year
- 2026: 2 · 2025: 7 · 2024: 33 · 2023: 6 · 2022: 10 · 2021: 26 · 2020: 3 · 2019: 6 · 2018: 5 · 2017: 1 · 2016: 8 · 2015: 1 · 2014: 2
- FWCI
- 4.73
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- Locations
- Dialogues in Clinical Neuroscience (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Keywords
- psychotherapy, major depressive disorder, anxiety disorders, functional brain activity, psychological intervention, functional neuroimaging
- MeSH terms
- Brain, Humans, Psychotherapy, Functional Neuroimaging
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