influence.ME: Tools for Detecting Influential Data in Mixed Effects Models
Open accessAbstract
influence.ME provides tools for detecting influential data in mixed effects models.The application of these models has become common practice, but the development of diagnostic tools has lagged behind.influence.ME calculates standardized measures of influential data for the point estimates of generalized mixed effects models, such as DFBETAS, Cook's distance, as well as percentile change and a test for changing levels of significance.influence.ME calculates these measures of influence while accounting for the nesting structure of the data.The package and measures of influential data are introduced, a practical example is given, and strategies for dealing with influential data are suggested.
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Written from the paper’s full text.
TL;DR
The paper introduces influence.ME, an R package for detecting influential cases in generalized mixed effects models estimated with lme4, providing DFBETAS, Cook’s distance, percentile change, and a test for changing significance while accounting for nesting. In a 23-school example, deleting school 7472 changed the school-level structure effect from non-significant to significant.
Key findings
- influence.ME calculates standardized influence measures for mixed effects models: DFBETAS, Cook’s distance, percentile change, and a significance-change test (`sigtest`), plus plotting and `exclude.influence` for deleting identified cases.
- In the example with 519 students in 23 schools, the original model estimated the structure effect as -2.0950 (SE 1.3237, t = -1.583, not significant) and the homework effect as 2.3938 (SE 0.2771, t = 8.640).
- The DFBETAS cut-off was 2/√23 = .41; school 7472 had a structure DFBETAS of 1.254990963, exceeding the cut-off. The Cook’s distance cut-off was 4/23 = .17; school 7472 had a Cook’s distance of 1.575002.
- After excluding school 7472, the model used 496 observations in 22 groups and estimated the structure effect as -3.8949 (SE 1.4342, t = -2.716), now statistically significant. For lower-level observations, the Cook’s distance cut-off was 4/519 = .0077; students 88 and 89 exceeded it for the structure estimate, but `sigtest` showed no significance changes.
Methods
- The paper describes the influence.ME package and demonstrates it with the `school23` data, a subset of NELS-88 containing 519 students nested in 23 schools, using a linear mixed model: `math ~ homework + structure + (1 | school.ID)` estimated with lme4.
- The `influence` function iteratively deletes each higher-level group, or with `obs=TRUE` each lower-level observation, and re-estimates the model; the resulting `estex` object is passed to `dfbetas`, `cooks.distance`, `pchange`, `sigtest`, and plotting functions.
- DFBETAS measures change in a single parameter standardized by the excluding-case standard error; Cook’s distance summarizes change across selected parameters; percentile change reports percentage change; `sigtest` compares test statistics after deletion to a user-specified value.
Limitations
- Stated: the leverage measure was not developed for generalized mixed effects models, so the package emphasizes influence on point estimates; the Langford and Lewis `delete=FALSE` procedure does not work with factor variables; the `influence` function can evaluate higher-level cases or single observations but not both at once; lower-level detection is often infeasible with many lower-level observations; the procedure can be computationally intensive; no cut-off is provided for percentile change.
- Evident: the worked example assumes math, homework, and structure are correctly measured at the interval level, and the paper does not report simulation or benchmark comparisons of the package’s performance.
Model-written summary. Check it against the paper before relying on it.
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Cites
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Claims the paper makes
0 of 16 cited sources checked · 0 supported · 0 flagged
- Findingnone given
influence.ME calculates these measures of influence while accounting for the nesting structure of the data.
“influence.ME calculates these measures of influence while accounting for the nesting structure of the data.”
Quote in the paperSubstantial claim - Findingcitation
influence.ME is an R-package that provides tools for detecting influential cases in mixed effects regression models estimated with lme4.
“We introduce influence.ME (Nieuwenhuis, Pelzer, and te Grotenhuis, 2012), an R-package that provides tools for detecting influential cases in mixed effects regression models estimated with lme4 (Bates and Maechler, 2010).”
Quote in the paperSubstantial claim0 of 2 sources checked- cites Nieuwenhuis, Pelzer, and te Grotenhuis, 2012
Not checked in the free run.
- cites Bates and Maechler, 2010
Not checked in the free run.
- Findingown data
In the school23 model, students spending more time on math homework score better on a math test.
“Based on these estimates, we may conclude that students spending more time on their math homework score better on a math test.”
Quote in the paperNot a substantial claim - Findingnone given
influence.ME provides a basic test for detecting whether single cases change the level of significance of an estimate, and therefore the ability to make inferences from the estimated model.
“It does, however, provide a basic test for detecting whether single cases change the level of significance of an estimate, and therefore the ability to make inferences from the estimated model.”
Quote in the paperSubstantial claim - Findingnone given
influence.ME contributes to existing options by providing several measures of influential data for generalized mixed effects models.
“The influence.ME package introduced here contributes to these existing options, by providing several measures of influential data for generalized mixed effects models.”
Quote in the paperSubstantial claim
- Findingreasoning
influence.ME provides a test for changes in the statistical significance of the fixed parameters in the mixed effects model.
“Although influence.ME cannot provide the leverage measure to detect this, it provides a test for changes in the statistical significance of the fixed parameters in the mixed effects model.”
Quote in the paperSubstantial claim - Findingown data
The DFBETAS for the structure variable exceeds the cutoff value of .41.
“The DFBETAS for the structure variable clearly exceeds the cut-off value of .41.”
Quote in the paperNot a substantial claim - Findingown data
In the original school23 model, class structure is not statistically significantly associated with math test scores.
“Regarding class structure, however, we do not find a statistically significant association with math test scores.”
Quote in the paperNot a substantial claim - Findingown data
Deletion of none of the students affected the level of significance of the structure variable or any other variable in the model.
“Using the sigtest function, however, showed that the deletion of none of the students from the data affected the level of significance of the structure variable, nor of any of the other variables in the model.”
Quote in the paperNot a substantial claim - Findingown data
The estimates of the homework variable change substantially with deletion of several schools, as indicated by high DFBETAS.
“Also, the estimates of the homework variable changes substantially with the deletion of several schools, as indicated by the high values of DF-BETAS.”
Quote in the paperNot a substantial claim - Premisecitation
The analysis of residuals cannot be used for the detection of influential cases.
“The analysis of residuals cannot be used for the detection of influential cases (Crawley, 2007).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Crawley, 2007
Not checked in the free run.
- Premisecitation
Van der Meer, te Grotenhuis, and Pelzer (2010) were unable to find any country-level comparative studies involving more than 54 countries.
“For instance, Van der Meer, te Grotenhuis, and Pelzer (2010) were unable to find any country-level comparative studies involving more than 54 countries.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Van der Meer, te Grotenhuis, and Pelzer (2010)
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- Interpretationcitation
With a relatively low number of countries, a single country can easily be overly influential on the parameter estimates of one or more country-level variables.
“With such a relatively low number of countries, a single country can easily be overly influential on the parameter estimates of one or more of the country-level variables.”
Quote in the paperSubstantial claim - Interpretationreasoning
Existing procedures that do not account for nesting fail to detect that higher-level cases may be influential on estimates of variables measured at that level.
“As a result, these existing procedures fail to detect that higher-level cases may be influential on estimates of variables measured at specifically that level.”
Quote in the paperSubstantial claim- Rests on an assumption: Most existing procedures for detecting influential data do not account for the nesting structure of the data.
- Interpretationreasoning
Influential cases run against distributional assumptions associated with regression models and limit the validity and generalizability of regression models in which they are present.
“This runs against distributional assumptions associated with regression models, and as a result limits the validity and generalizability of regression models in which influential cases are present.”
Quote in the paperSubstantial claim - Premisereasoning
In social science applications of mixed models, testing for influential data is especially important because these models are frequently based on large numbers of observations at the individual level while the number of higher-level groups is relatively small.
“In social science applications of mixed models the testing for influential data is especially important, since these models are frequently based on large numbers of observations at the individual level while the number of higher level groups is relatively small.”
Quote in the paperSubstantial claim - Interpretationreasoning
The simple inclusion or exclusion of such a single case may lead to substantially different regression estimates.
“The simple inclusion or exclusion of such a single case may then lead to substantially different regression estimates.”
Quote in the paperSubstantial claim - Premisereasoning
An influential case is not always an outlier.
“However, an influential case is not always an outlier.”
Quote in the paperSubstantial claim - Premisecitation
Langford and Lewis (1998) developed a procedure in which the mixed effects model is modified to neutralize the group's influence on the higher-level estimate while allowing lower-level observations nested within that group to help estimate lower-level predictors.
“Langford and Lewis (1998) developed a procedure in which the mixed effects model is modified to neutralize the group's influence on the higher-level estimate, while at the same time allowing the lower-level observations nested within that group to help estimate the effects of the lowerlevel predictors in the model.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Langford and Lewis (1998)
Not checked in the free run.
- Premisenone given
Even when cases are not influential on the point estimates of the regression model, cases can still influence the standard errors of these estimates.
“As discussed above, even when cases are not influential on the point estimates (BETAS) of the regression model, cases can still influence the standard errors of these estimates.”
Quote in the paperNot a substantial claim - Interpretationreasoning
The amount of influence a case exerts on the regression slope is determined by how well its observed score is fitted by the specified regression model and by its scores on the independent variables.
“The reason for this is that the amount of influence a case exerts on the regression slope is not only determined by how well its (observed) score is fitted by the specified regression model, but also by its score(s) on the independent variable(s).”
Quote in the paperSubstantial claim - Premisereasoning
Single cases can also bias the confidence intervals of regression estimates.
“Single cases, however, can also bias the confidence intervals of these estimates.”
Quote in the paperSubstantial claim - Interpretationreasoning
The specific procedure suggested by Langford and Lewis (1998) does not work when factor-variables are used in the regression model.
“As a result of the specific modification of the model-specification, this specific procedure suggested by Langford and Lewis (1998) does not work when factor-variables are used in the regression model.”
Quote in the paperSubstantial claim - Interpretationreasoning
Inferences made to the population from models in which such cases are present may be incorrect.
“Inferences made to the population from models in which such cases are present may be incorrect.”
Quote in the paperSubstantial claim - Interpretationreasoning
If a case has very extreme scores on the independent variables but is fitted very well by a regression model and has a low deleted standardized residual, it is not necessarily overly influencing the outcomes of the regression model.
“However, if a case has very extreme scores on the independent variable(s) but is fitted very well by a regression model, and if this case has a low deleted (standardized) residual, this case is not necessarily overly influencing the outcomes of the regression model.”
Quote in the paperSubstantial claim - Premisereasoning
Outliers are not necessarily influential cases.
“Just as influential cases are not necessarily outliers, outliers are not necessarily influential cases.”
Quote in the paperSubstantial claim - Interpretationcitation
Adding important variables to the model may solve the problem of influential data.
“Thus, adding important variables to the model may solve the problem of influential data.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Lieberman (2005)
Not checked in the free run.
- Interpretationown data
High DFBETAS for the homework variable suggest substantial differences between schools in average homework time.
“The observation that high values of DFBETAS were found for the homework variable, suggests that substantial differences between these schools exist in terms of how much time students spend on average on their homework.”
Quote in the paperNot a substantial claim - Interpretationown data
After excluding school 7472, higher levels of class structure are associated with lower math test scores, controlling for homework.
“So, now these model outcomes indicate that higher levels of class structure indeed are associated with lower math test scores, even when controlled for the students' homework efforts.”
Quote in the paperSubstantial claim - Interpretationreasoning
If additional variables in the model can account for an observation's extreme scores on one or more variables, the case may no longer be an influential one.
“Nevertheless, if additional variables in the model can account for the fact that an observation has extreme scores on one or more variables, the case may no longer be an influential one.”
Quote in the paperSubstantial claim
- May combine two claims. 15
- Classified as probably not a substantial claim. 56
- The quote only partly states this claim. 2
May combine two claims.
Findingnone giveninfluence.ME calculates standardized measures of influential data for the point estimates of generalized mixed effects models, including DFBETAS, Cook's distance, percentile change, and a test for changing levels of significance.
“influence.ME calculates standardized measures of influential data for the point estimates of generalized mixed effects models, such as DFBETAS, Cook's distance, as well as percentile change and a test for changing levels of significance.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
Findingnone giveninfluence.ME provides tools for detecting influential data in mixed effects models.
“influence.ME provides tools for detecting influential data in mixed effects models.”
- Also stated in: § Additional information · plain
“influence.ME provides tools for detecting influential data in mixed effects models.”
Quote in the paperSubstantial claim- Rests on an assumption: The application of mixed effects models has become common practice, but the development of diagnostic tools lags behind.
- Also stated in: § Additional information · plain
Classified as probably not a substantial claim. May combine two claims.
Findingnone givenThe paper introduces the measure of percentile change and a test for changing levels of significance of the fixed parameters.
“In addition, we introduce the measure of percentile change and a test for changing levels of significance of the fixed parameters.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenIn influence.ME, values for Cook's distance in mixed effects models are calculated using the function cooks.distance, which takes the object returned from influence as input.
“In influence.ME, values for Cook's distance in mixed effects models are calculated using the function cooks.distance,which takes the object returned from influence as input.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims. The quote only partly states this claim.
Findingnone giveninfluence.ME offers four standardized measures of influence: DFBETAS, Cook's distance, percentile change, and a test for changes in significance.
“influence.ME offers four such measures, which are detailed in this section.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based).
FindingreasoningDetecting influence of lower-level observations is supported for applications in various disciplines where mixed effects models are typically applied to only a limited number of observations per group.
“Detecting influence of lower-level observations is supported for applications in various disciplines where mixed effects models are typically applied to only a limited number of observations per group.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
FindingreasoningThe current installment of influence.ME emphasizes detecting the influence of cases on the point estimates of generalized mixed effect models.
“Consequently, the current installment of influence.ME emphasizes detecting the influence of cases on the point estimates of generalized mixed effect models.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataThe school23 data.frame provides information on the performance of 519 students in 23 schools.
“The influence.ME package contains the school23 data.frame, that provides information on the performance of 519 students in 23 schools.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone giveninfluence.ME provides the Langford and Lewis (1998) functionality, accessed by specifying delete=FALSE as an option to the influence function.
“influence.ME provides this functionality, which is accessed by specifying delete=FALSE as an option to the influence function.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
FindingcitationThe plot function takes the output of the influence function to create a dotplot of a selected measure of influence.
“The plot function takes the output of the influence function to create a dotplot of a selected measure of influence (cf.Sarkar, 2008).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Sarkar, 2008
Not checked in the free run.
Classified as probably not a substantial claim.
Findingnone giveninfluence.ME allows for detecting the influence of lower-level cases in the mixed effects model.
“Finally, influence.ME also allows for detecting the influence of lower-level cases in the mixed effects model.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
Findingnone givenThe sigtest function tests whether excluding the influence of a single case changes the statistical significance of any of the variables in the model.
“The sigtest function tests whether excluding the influence of a single case changes the statistical significance of any of the variables in the model.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
FindingreasoningThe returned object of class estex can be passed to functions calculating standardized measures of influence such as DFBETAS and Cook's Distance.
“The returned object of class”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenAll four measures of influence discussed above can be plotted.
“All four measures of influence discussed above, can also be plotted.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based).
Findingnone givenThe influence function returns an object with information on how much the parameter estimates in a mixed effects model change after the observations of higher-level groups and their individual-level observations were removed iteratively.
“The influence function described above returns an object with information on how much the parameter estimates in a mixed effects model change, after the (influence of) observations of higher-level groups and their individual-level observations were removed from it iteratively.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
FindingreasoningStudent's class and school are equivalent in the school23 data because only one class per school is available.
“Student's class and school are equivalent in this data, since only one class per school is available.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenIn influence.ME, values for DFBETAS in mixed effects models can be calculated using the function dfbetas, which takes the object returned from influence as input.
“In influence.ME, values for DFBETAS in mixed effects models can be calculated using the function dfbetas, which takes the object returned from influence as input.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenThe default option of dfbetas is to calculate DFBETAS for estimates of all fixed effects in the model.
“The default option of dfbetas is to calculate DFBETAS for estimates of all fixed effects in the model.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
Findingnone givenThe influence function in influence.ME performs the procedure of deleting all observations nested within a single higher level group, re-estimating the regression model, and evaluating the change in estimated regression parameters automatically, returning an object with parameter estimates excluding the influence of each higher level group separately.
“The influence function in the influence.ME package performs this procedure automatically, and returns an object containing information on the parameter estimates excluding the influence of each higher level group separately.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenThe significance test in sigtest is based on the test statistic provided by the lme4 package.
“This test of significance is based on the test statistic provided by the lme4 package.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.
Findingnone givenThe influence function can either determine the influence of higher-level cases, or of single observations, but not both at the same time.
“The influence function can either determine the influence of higher-level cases, or of single observations, but not both at the same time.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataCook's distance and sigtest results both indicate that school 7472 overly influences the regression outcomes regarding the school-level structure variable.
“In the case of our example, the results for Cook's Distance and the results of this test for changing levels of significance both indicate that school number 7472 overly influences the regression outcomes regarding the school-level structure variable.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataBoth the structure and homework variables are highly susceptible to the influence of single schools.
“Based on Figure 2, it is clear that both the structure and the homework variables are highly susceptible to the influence of single schools.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataFor the structure variable, the estimate is influenced most strongly by observations in school 7472.
“The estimate for class structure in this model seems to be influenced most strongly by observations in school number 7472.”
Quote in the paperNot a substantial claimMay combine two claims. The quote only partly states this claim.
Findingown dataDeleting school 7472 from the model makes the structure variable's effect statistically significant, with the test statistic changing from -1.583 to -2.72.
“More importantly, though, the negative effect of the structure variable now is statistically significant, whereas it was not in the original model.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataVisual examination of aggregated school-level data suggests one school with class structure level 2 is an outlier and may overly influence the linear regression line.
“In this plot, it is clear that one single school represented in the lower-left corner of the graph seems to be an outlier, and -more importantly -the non-linear curve shown in this graph clearly indicates this single school with class structure level of 2 may overly influence a linear regression line estimated based on these data.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataDeletion of none of the schools changed the level of significance of the homework variable.
“These results are not shown here, but indicated that the deletion of none of the schools changed the level of significance of the homework variable.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Findingnone givenStudents 88 and 89 exert too much influence on the estimate of the structure variable.
“The output is not shown here, but the reader can verify that students with numbers 88 and 89 exert too much influence on the estimate of the structure variable.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
Premisenone givenTesting for influential cases in mixed effects regression models is important because influential data negatively influence the statistical fit and generalizability of the model.
“Testing for influential cases in mixed effects regression models is important, because influential data negatively influence the statistical fit and generalizability of the model.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Premisenone givenThe application of mixed effects regression models has become common practice in the field of social sciences.
“The application of mixed effects regression models has become common practice in the field of social sciences.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based).
Interpretationnone givenIf a single case has extremely high or low scores on the dependent variable relative to its expected value, or on one or more independent variables, it may overly influence the regression parameters by pulling the estimated regression line towards itself.
“However, if a single case has extremely high or low scores on the dependent variable relative to its expected value -given other variables in the model, one or more of the independent variables, or both -this case may overly influence the regression parameters by 'pulling' the estimated regression line towards itself.”
Quote in the paperNot a substantial claim- Rests on an assumption: All cases used to estimate a regression model exert some level of influence on the regression parameters.
Classified as probably not a substantial claim.
PremisecitationAs used in the social sciences, mixed effects regression models take into account that observations on individual respondents are nested within higher-level groups such as schools, classrooms, states, and countries.
“As used in the social sciences, mixed effects regression models take into account that observations on individual respondents are nested within higherlevel groups such as schools, classrooms, states, and countries (Snijders and Bosker, 1999), and are often referred to as multilevel regression models.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Snijders and Bosker, 1999
Not checked in the free run.
Classified as probably not a substantial claim.
Premisenone givenThese base R plots are not available for mixed effects models.
“These plots, however, are not available for mixed effects models.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
PremisecitationValues exceeding the DFBETAS cut-off value are regarded as overly influencing the regression outcomes for that specific estimate.
“Values exceeding this cut-off value are regarded as overly influencing the regression outcomes for that specific estimate.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Interpretationnone givenRegarding mixed models, DFBETAS relates to the influence a higher-level unit has on the parameter estimate.
“Regarding mixed models, this relates to the influence a higher-level unit has on the parameter estimate.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
InterpretationreasoningA higher leverage means more extreme scores on the independent variables and a greater potential of overly influencing the regression outcomes.
“A higher leverage means more extreme scores on the independent variable(s), and a greater potential of overly influencing the regression outcomes.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based).
Premisenone givenIn detecting influential data in mixed effects models, the key focus is on changes in the estimates of variables measured at the group-level.
“In detecting influential data in mixed effects models, the key focus is on changes in the estimates of variables measured at the group-level.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based).
Premisenone givenThe measure of leverage was not developed for generalized mixed effects models.
“The limitation is that, unfortunately, as far as we are aware, the measure of leverage was not developed for generalized mixed effects models.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
Premisenone givenCook's distance provides a summary measure for the influence a higher level unit exerts on all parameter estimates simultaneously, or a selection thereof.
“Cook's distance provides a summary measure for the influence a higher level unit exerts on all parameter estimates simultaneously, or a selection thereof.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
PremisereasoningTo apply the logic of detecting influential data to generalized mixed effects models, one has to measure the influence of a particular higher level group on the estimates of a predictor measured at that level.
“To apply the logic of detecting influential data to generalized mixed effects models, one has to measure the influence of a particular higher level group on the estimates of a predictor measured at that level.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S4 (based).
Premisenone givenMost mixed effects regression models estimate the effects of both lower-level and higher-level variables simultaneously.
“However, most mixed effects regression models estimate the effects of both lower-level and higher-level variables simultaneously.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
InterpretationreasoningSince the procedure of the influence function entails re-estimating mixed effects models several times, it can be computationally intensive.
“Since the procedure of the influence function entails re-estimating mixed effects models several times, this can be computationally intensive.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationDFBETAS is a standardized measure that indicates the level of influence observations have on single parameter estimates.
“DFBETAS is a standardized measure that indicates the level of influence observations have on single parameter estimates (Fox, 2002).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Fox, 2002
Not checked in the free run.
May combine two claims.
Interpretationnone givenSince neither outliers nor cases with high leverage are necessarily influential, a different procedure is required for detecting influential cases.
“Since neither outliers, nor cases with a high leverage, are necessarily influential, a different procedure is required for detecting influential cases.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationAs a rule of thumb, a cut-off value for DFBETAS is 2/√n, where n is the number of groups in the grouping factor under evaluation.
“As a rule of thumb, a cut-off value is given for DFBETAS (Belsley et al., 1980): 2/ √ n in which n, the number of observations, refers to the number of groups in the grouping factor under evaluation (and not to the number of observations nested within the group under investigation).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Belsley et al., 1980
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationThe LMERConvenienceFunctions package provides model criticism plots, including the density of the model residuals and the fitted values versus the standardized residuals.
“The LMERConvenienceFunctions package provides model criticism plots, including the density of the model residuals and the fitted values versus the standardized residuals (Tremblay, 2012).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Tremblay, 2012
Not checked in the free run.
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PremisecitationDFBETAS is a standardized measure of the absolute difference between the estimate with a particular case included and the estimate without that particular case.
“First, DFBETAS is a standardized measure of the absolute difference between the estimate with a particular case included and the estimate without that particular case (Belsley, Kuh, and Welsch, 1980).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Belsley, Kuh, and Welsch, 1980
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Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.
Interpretationnone givenCases with high leverage but a low deleted residual compress standard errors, while cases with low leverage and a high deleted residual inflate standard errors.
“Cases with high leverage but a low deleted residual compress standard errors, while cases with low leverage and a high deleted residual inflate standard errors.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationCook's distance provides an overall measurement of the change in all parameter estimates, or a selection thereof.
“Second, Cook's distance provides an overall measurement of the change in all parameter estimates, or a selection thereof (Cook, 1977).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Cook, 1977
Not checked in the free run.
Classified as probably not a substantial claim.
Premisenone givenThe basic rationale behind measuring influential cases is that when single cases are iteratively omitted from the data, models based on these data should not produce substantially different estimates.
“The basic rationale behind measuring influential cases is based on the principle that when single cases are iteratively omitted from the data, models based on these data should not produce substantially different estimates.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Interpretationnone givenIf Cook's distance is calculated based on a single parameter, the Cook's distance equals the squared value of DFBETAS for that parameter.
“As a final note, it is pointed out that if Cook's distance is calculated based on a single parameter, the Cook's distance equals the squared value of DFBE-TAS for that parameter.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisereasoningThe nature of the test statistic varies between different distributional families in generalized mixed effects models.
“The nature of this statistic varies between different distributional families in the generalized mixed effects models.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Premisenone givenThe base R installation provides various plots for regression models, including residuals versus fitted scores, Cook's distances, and leverage versus deleted residuals.
“The base R installation provides various plots for regression models, including but not limited to plots showing residuals versus the fitted scores, Cook's distances, and the leverage versus the deleted residuals.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Premisenone givenThe LMERConvenienceFunctions package only is applicable for linear mixed effects models.
“However, while this package works with the lme4 package, it only is applicable for linear mixed effects models.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationThe school23 data are a subset of the NELS-88 data.
“These data are a subset of the NELS-88 data (National Education Longitudinal Study of 1988).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites NELS-88
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
InterpretationreasoningNo cut-off value is provided for percentile change because determining what percent change is too large depends on the goal for which the model was estimated and the nature of the hypotheses tested.
“No cut-off value is provided, for determining what percent change in parameter estimate is considered too large will primarily depend on the goal for which the model was estimated and, more specifically, the nature of the hypotheses that are tested.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
InterpretationreasoningIf the model parameters change substantially after a single case is excluded, this case may be regarded as too influential.
“If the model parameters change substantially after a single case is excluded, this case may be regarded as too influential.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Interpretationnone givenIn social science applications of mixed effects models, with a great number of lower-level observations nested in a limited number of groups, detecting influence of lower-level observations will not always be feasible.
“In social science applications of mixed effects models, with a great number of lower-level observations nested in a limited number of groups, this will not always be feasible.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
Interpretationnone giveninfluence.ME calculates standardized measures of influential data such as DFBETAS and Cook's distance, as well as percentile change and a test for changing statistical significance of fixed parameter estimates.
“influence.ME calculates standardized measures of influential data such as DFBETAS and Cook's distance, as well as percentile change and a test for changing in statistical significance of fixed parameter estimates.”
Quote in the paperSubstantial claim- Rests on an assumption: The application of mixed effects models has become common practice, but the development of diagnostic tools lags behind.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationThe cut-off value of DFBETAS equals 2/√n, which in this case equals .41.
“The cut-off value of DFBETAS equals 2/ √ n (Belsley et al., 1980), which in this case equals 2/ √ 23 = .41.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Belsley et al., 1980
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationThe presence of outliers may indicate that one or more important variables were omitted from the model.
“He argues that the presence of outliers may indicate that one or more important variables were omitted from the model.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Lieberman (2005)
Not checked in the free run.
May combine two claims.
Interpretationnone givenCases can influence point estimates without affecting their level of significance, or affect the level of significance without overly affecting the point estimate itself.
“Cases can influence the point estimates without affecting their level of significance, or affect the level of significance without overly affecting the point estimate itself.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Interpretationnone givenAn influential case is not necessarily an outlier in a regression model.
“We discussed above that an influential case is not necessarily an outlier in a regression model.”
Quote in the paperNot a substantial claim
The paper relies on this without support.
Diagnostic tools to evaluate fitted mixed effects models lag behind their increasing popularity.
“Despite these models' increasing popularity, diagnostic tools to evaluate fitted models lag behind.”
The paper relies on this without support.
Most existing procedures for detecting influential data do not account for the nesting structure of the data.
“However, most existing procedures do not account for the nesting structure of the data.”
The paper relies on this without support.
All cases used to estimate a regression model exert some level of influence on the regression parameters.
“All cases used to estimate a regression model exert some level of influence on the regression parameters.”
The authors state this as an assumption.
The math, homework, and structure variables were correctly measured at the interval level.
“For the purpose of our example, we assume here that the math, homework, and structure variables were correctly measured at the interval level.”
The paper relies on this without support.
The application of mixed effects models has become common practice, but the development of diagnostic tools lags behind.
“The application of these models has become common practice, but the development of diagnostic tools lag behind.”
The paper relies on this without support.
Overly influential data are a problem especially encountered in models based on a limited number of cases.
“Since overly influential data are a problem especially encountered in models based on a limited number of cases, a straightforward remedy would be to observe more cases in the population of interest.”
The paper relies on this without support.
If data are used to estimate too complex models, or if parameterization is incorrect, influential cases are more likely to occur.
“If the data are used to estimate too complex models, or if parameterization is incorrect, influential cases are more likely to occur.”
The paper relies on this without support.
In social science applications of mixed effects models, higher-level groups are often readily accessible cases such as schools and countries, making it possible to obtain additional measurements to remedy influential data.
“However, in social science applications of mixed effects models, the higher-level groups are often readily accessible cases such as schools and countries.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
No evidence of influential outlying data was found.
“We screened for outliers within the multilevel modeling framework using the R package influence.ME (Nieuwenhuis, Pelzer, & Grotenhuis, 2012) and found no evidence of influential outlying data (all Cook’s distance < 1; Tabachnick & Fidell, 2007).”
From Enhancing social connectedness in anxiety and depression through amplification of positivity: Preliminary treatment outcomes and process of change (2020) · cites this paper as Nieuwenhuis, Pelzer, & Grotenhuis, 2012
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Cook's distances are shown in ascending order despite descending sort
MinorThe paper says sort=TRUE returns Cook's distances in descending order, but the displayed output runs from 6.825871e-06 up to 1.575002, in ascending order.
“In addition, the user can specify sort=TRUE to have the values for Cook's distance returned in descending order.”
“[,1] 24371 6.825871e-06 72292 1.524927e-05 ... 54344 2.256612e-01 7829 3.081222e-01 7472 1.575002e+00”
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Within‐individual repeatability in telomere length: A meta‐analysis in nonmammalian vertebrates
Kärkkäinen, T., Briga, M., Laaksonen, T., & Stier, A. (2021) · Molecular Ecology · doi:10.1111/mec.16155 · Cited by 40 · see citing works
Audience effect on domestic dogs’ behavioural displays and facial expressions
Pedretti, G., Canori, C., Marshall‐Pescini, S., Palme, R., Pelosi, A., & Valsecchi, P. (2022) · Scientific Reports · doi:10.1038/s41598-022-13566-7 · Cited by 40 · see citing works
Kelly, T. R., MacGillivray, H. L., Sarquis‐Adamson, Y., Watson, M. J., Hobson, K. A., & MacDougall‐Shackleton, E. A. (2016) · Behavioral Ecology and Sociobiology · doi:10.1007/s00265-016-2191-2 · Cited by 40 · see citing works
Garamszegi, L. Z., Mueller, J. C., Markó, G., Szász, E., Zsebők, S., Herczeg, G., Eens, M., & Török, J. (2014) · Ecology and Evolution · doi:10.1002/ece3.1041 · Cited by 39 · see citing works
Dröscher, I., & Kappeler, P. M. (2014) · Behavioral Ecology and Sociobiology · doi:10.1007/s00265-014-1810-z · Cited by 38 · see citing works
Bufford, J. L., Hulme, P. E., Sikes, B. A., Cooper, J., Johnston, P. R., & Duncan, R. P. (2016) · New Phytologist · doi:10.1111/nph.14077 · Cited by 37 · see citing works
Luke, S. G., Darowski, E. S., & Gale, S. D. (2018) · Memory & Cognition · doi:10.3758/s13421-018-0798-4 · Cited by 36 · see citing works
Andersson, E., Crowley, J. J., Lindefors, N., Ljótsson, B., Hedman‐Lagerlöf, E., Boberg, J., Alaoui, S. E., Karlsson, R., Lu, Y., Mattheisen, M., et al. (2018) · Molecular Psychiatry · doi:10.1038/s41380-018-0289-9 · Cited by 36 · see citing works
Sanchez, M., Milà, C., Sreekanth, V., Balakrishnan, K., Sambandam, S., Nieuwenhuijsen, M. J., Kinra, S., Marshall, J. D., & Tonne, C. C. (2019) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/s41370-019-0150-5 · Cited by 35 · see citing works
Below the canopy: global trends in forest vertebrate populations and their drivers
Green, E. J., McRae, L., Freeman, R., Harfoot, M. B. J., Hill, S. L. L., Baldwin-Cantello, W., & Simonson, W. D. (2020) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2020.0533 · Cited by 35 · see citing works
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Honey bees increase social distancing when facing the ectoparasite Varroa destructor
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Is there such a thing as too long childcare leave?
Nieuwenhuis, R., Need, A., & van der Kolk, H. (2017) · International Journal of Sociology and Social Policy · doi:10.1108/ijssp-07-2015-0074 · Cited by 34 · see citing works
Self-citationAge and social affinity effects on contact call interactions in free-ranging spider monkeys
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Klaus, J., Mädebach, A., Oppermann, F., & Jescheniak, J. D. (2016) · Quarterly Journal of Experimental Psychology · doi:10.1080/17470218.2016.1167926 · Cited by 33 · see citing works
Talking to Cows: Reactions to Different Auditory Stimuli During Gentle Human-Animal Interactions
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Hood, A. S. C., Aryawan, A. A. K., Advento, A. D., Purnomo, D., Wahyuningsih, R., Luke, S. H., Ps, S., Snaddon, J. L., Foster, W. A., Caliman, J., et al. (2019) · Frontiers in Forests and Global Change · doi:10.3389/ffgc.2019.00051 · Cited by 32 · see citing works
O’Connor, R. S., Pogam, A. L., Young, K. G., Robitaille, F., Choy, E. S., Love, O. P., Elliott, K. H., Hargreaves, A. L., Berteaux, D., Tam, A., et al. (2021) · Ecology and Evolution · doi:10.1002/ece3.7141 · Cited by 32 · see citing works
Hedgerows as a habitat for forest plant species in the agricultural landscape of Europe
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Dominance, gender, and season influence food patch use in a group-living, solitary foraging canid
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Social immunity modulates competition between coinfecting pathogens
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Accelerated seed dispersal along linear disturbances in the Canadian oil sands region
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- Authors
- Nieuwenhuis, R., Grotenhuis, M., & Pelzer, B.
- Venue
- The R Journal
- Publisher
- The R Foundation
- Published
- 2012
- Volume
- 4
- Issue
- 2
- Pages
- 38
- ISSN
- 2073-4859 (ISSN-L)
- OpenAlex
- W1549371580
- Semantic Scholar
- c6d41ed109eb79b026ba2d1fb769b6ebf525ebd4
- Cited by
- 442
- References
- 18
- Citations by year
- 2026: 29 · 2025: 36 · 2024: 45 · 2023: 38 · 2022: 64 · 2021: 63 · 2020: 33 · 2019: 28 · 2018: 24 · 2017: 26 · 2016: 22 · 2015: 17 · 2014: 12 · 2013: 5
- FWCI
- 10.39
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- The R Journal (publishedVersion, cc-by)
- Lincoln (University of Nebraska) (submittedVersion, cc-by)
- Radboud Repository (Radboud University) (submittedVersion)
- University of Twente Research Information (submittedVersion)
- Radboud Repository (Radboud University) (submittedVersion, other-oa)
- University of Twente Research Information (submittedVersion, other-oa)
- Topics
- Physical Sciences › Mathematics › Statistics and Probability › Advanced Statistical Methods and Models
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Bayesian Inference
- Physical Sciences › Computer Science › Artificial Intelligence › Data Analysis with R
- Keywords
- mixed models, generalized linear mixed models, Cook's distance, nested data, influence diagnostics, R package
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-09.
Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-09.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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