The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Food allergies and food-induced anaphylaxis: role of cofactors
Abstract
Food allergies and food-induced anaphylaxis are important health problems. Several cofactors modulating the onset of anaphylaxis have been identified. In the presence of cofactors, allergic reactions may be induced at lower doses of food allergens and/or become severe. Exercise and concomitant infections are well-documented cofactors of anaphylaxis in children. Other factors such as consumption of nonsteroidal anti-inflammatory drugs, alcohol ingestion, and stress have been reported. Cofactors reportedly play a role in approximately 30% of anaphylactic reactions in adults and 14%–18.3% in children. Food-dependent exercise-induced anaphylaxis (FDEIA) is the best-studied model of cofactor-induced anaphylaxis. Wheat-dependent exercise-induced anaphylaxis, the most common FDEIA condition, has been studied the most. The mechanisms of action of cofactors have not yet been fully identified. This review aims to educate clinicians on recent developments in the role of cofactors and highlight the importance of recognizing cofactors in food allergies and food-induced anaphylaxis.
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“Similarly, exercise can amplify the severity of allergic reactions by increasing gastrointestinal permeability and altering blood flow dynamics, particularly to the digestive system.”
From Pollen–Food Allergy Syndrome: Allergens, Clinical Insights, Diagnostic and Therapeutic Challenges (2024) · cites this paper as [35]
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“Cofactors such as physical exercise, alcohol consumption, or the use of nonsteroidal anti-inflammatory drugs (NSAIDs) can exacerbate symptoms, potentially tipping mild reactions into severe systemic responses [35].”
From Pollen–Food Allergy Syndrome: Allergens, Clinical Insights, Diagnostic and Therapeutic Challenges (2024) · cites this paper as [35]
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Cited by
Sorted by citations
Pollen–Food Allergy Syndrome: Allergens, Clinical Insights, Diagnostic and Therapeutic Challenges
Haidar, L., Bănărescu, C. F., Uța, C., Moldovan, S. I., Zimbru, E.-L., Zimbru, R.-I., Ciurariu, E., Georgescu, M., & Panaitescu, C. (2024) · Applied Sciences · doi:10.3390/app15010066 · Cited by 21
Metadata
- Authors
- shin, M.
- ORCID
- shin, Meeyong
- Venue
- Clinical and Experimental Pediatrics
- Publisher
- Korean Pediatric Society
- Published
- 2021-08-15
- Volume
- 64
- Issue
- 8
- Pages
- 393-399
- ISSN
- 2713-4148
- PMC
- PMC8342881
- Cited by
- 36
- References
- 4
- Language
- en
- Funders
- Soonchunhyang University
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