The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.
Advances in Hyaluronic Acid for Biomedical Applications
Open accessAbstract
Hyaluronic acid (HA) is a large non-sulfated glycosaminoglycan that is the main component of the extracellular matrix (ECM). Because of its strong and diversified functions applied in broad fields, HA has been widely studied and reported previously. The molecular properties of HA and its derivatives, including a wide range of molecular weights but distinct effects on cells, moisture retention and anti-aging, and CD44 targeting, promised its role as a popular participant in tissue engineering, wound healing, cancer treatment, ophthalmology, and cosmetics. In recent years, HA and its derivatives have played an increasingly important role in the aforementioned biomedical fields in the formulation of coatings, nanoparticles, and hydrogels. This article highlights recent efforts in converting HA to smart formulation, such as multifunctional coatings, targeted nanoparticles, or injectable hydrogels, which are used in advanced biomedical application.
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Cites
Biomedical applications of hydrogels: A review of patents and commercial products
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Hyaluronic Acid Hydrogels for Biomedical Applications
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Hyaluronic acid—Based wound dressings: A review
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Application of hyaluronic acid as carriers in drug delivery
Huang, G., & Huang, H. (2018) · Drug Delivery · doi:10.1080/10717544.2018.1450910 · Cited by 474
Vasvani, S., Kulkarni, P., & Rawtani, D. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.11.066 · Cited by 473
The application of hyaluronic acid in bone regeneration
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Chitosan and hyaluronic-based hydrogels could promote the infected wound healing
Bai, Q., Gao, Q., Hu, F., Zheng, C., Chen, W., Sun, N., Liu, J., Zhang, Y., Wu, X., & Lu, T. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.123271 · Cited by 125
Piotrowska, U., Szatko, J., Nowakowska, A., Klimaszewska, E., Ogorzałek, M., & Sobczak, M. (2025) · Marine Drugs · doi:10.3390/md23120467 · Cited by 14
Effects of a Combination of Polynucleotide and Hyaluronic Acid for Treating Osteoarthritis
Choi, S. H., Kim, H. C., Jang, S. G., Lee, Y. J., Heo, J. Y., Kweon, G. R., & Ryu, M. J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25031714 · Cited by 14
Yu, Z., Zhu, C., Zhang, H., Liu, C., Wei, R., Duan, R., Liu, Y., Bian, X., Piao, H., Wang, W., et al. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.144072 · Cited by 3
Metadata
- Authors
- Yasin, A., Ren, Y., Li, J., Sheng, Y., Cao, C., & Zhang, K.
- Venue
- Frontiers in Bioengineering and Biotechnology
- Publisher
- Frontiers Media SA
- Published
- 2022-07-04
- Volume
- 10
- Pages
- 910290-910290
- ISSN
- 2296-4185 (ISSN-L)
- OpenAlex
- W4283792878
- Cited by
- 259
- References
- 74
- FWCI
- 14.48
- Type
- journal article
- Language
- en
- Open access
- gold
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- Yasin, A., Ren, Y., Li, J., Sheng, Y., Cao, C., & Zhang, K. (2022). Advances in Hyaluronic Acid for Biomedical Applications. Frontiers in Bioengineering and Biotechnology. https://doi.org/10.3389/fbioe.2022.910290
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.