The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Applications and emerging trends of hyaluronic acid in tissue engineering, as a dermal filler and in osteoarthritis treatment
Open accessAbstract
Hyaluronic acid (HA) is a naturally occurring biodegradable polymer with a variety of applications in medicine including scaffolding for tissue engineering, dermatological fillers, and viscosupplementation for osteoarthritis treatment. HA is available in most connective tissues in body fluids such as synovial fluid and the vitreous humor of the eye. HA is responsible for several structural properties of tissues as a component of extracellular matrix (ECM) and is involved in cellular signaling. Degradation of HA is a step-wise process that can occur via enzymatic or non-enzymatic reactions. A reduction in HA mass or molecular weight via degradation or slowing of synthesis affects physical and chemical properties such as tissue volume, viscosity, and elasticity. This review addresses the distribution, turnover, and tissue-specific properties of HA. This information is used as context for considering recent products and strategies for modifying the viscoelastic properties of HA in tissue engineering, as a dermal filler, and in osteoarthritis treatment.
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Cites
Hydrogels for tissue engineering: scaffold design variables and applications
Drury, J. L., & Mooney, D. J. (2003) · Biomaterials · doi:10.1016/s0142-9612(03)00340-5 · Cited by 5,136
Toll-like receptors: critical proteins linking innate and acquired immunity
Akira, S., Takeda, K., & Kaisho, T. (2001) · Nature Immunology · doi:10.1038/90609 · Cited by 4,777
Hyaluronan: from extracellular glue to pericellular cue
Toole, B. P. (2004) · Nature Reviews Cancer · doi:10.1038/nrc1391 · Cited by 2,125
Hyaluronic acid (hyaluronan): A review
Necas, J., Bartosikova, L., Brauner, P., & Kolar, J. (2008) · Veterinární medicína · doi:10.17221/1930-vetmed · Cited by 998
Hyaluronan in Tissue Injury and Repair
Jiang, D., Liang, J., & Noble, P. W. (2007) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.23.090506.123337 · Cited by 835
Controlled Degradation and Mechanical Behavior of Photopolymerized Hyaluronic Acid Networks
Burdick, J. A., Chung, C., Jia, X., Randolph, M. A., & Langer, R. (2005) · Biomacromolecules · doi:10.1021/bm049508a · Cited by 777
Hyaluronan Fragments Act as an Endogenous Danger Signal by Engaging TLR2
Scheibner, K. A., Lutz, M. A., Boodoo, S., Fenton, M. J., Powell, J. D., & Horton, M. R. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.2.1272 · Cited by 708
Looking Older: Fibroblast Collapse and Therapeutic Implications
Fisher, G. J., Varani, J., & Voorhees, J. J. (2008) · Archives of Dermatology · doi:10.1001/archderm.144.5.666 · Cited by 540
Cited by
Afewerki, S., Sheikhi, A., Kannan, S., Ahadian, S., & Khademhosseini, A. (2019) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10124 · Cited by 409
Advances in Hyaluronic Acid for Biomedical Applications
Yasin, A., Ren, Y., Li, J., Sheng, Y., Cao, C., & Zhang, K. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.910290 · Cited by 259
Biomaterials / bioinks and extrusion bioprinting
Chen, X. B., Fazel Anvari-Yazdi, A., Duan, X., Zimmerling, A., Gharraei, R., Sharma, N. K., Sweilem, S., & Ning, L. (2023) · Bioactive Materials · doi:10.1016/j.bioactmat.2023.06.006 · Cited by 244
Extracellular Matrix‐Based Strategies for Immunomodulatory Biomaterials Engineering
Rowley, A. T., Nagalla, R. R., Wang, S., & Liu, W. F. (2019) · Advanced Healthcare Materials · doi:10.1002/adhm.201801578 · Cited by 193
Rheological considerations of pharmaceutical formulations: focus on viscoelasticity
Budai, L., Budai, M., Fülöpné Pápay, Z. E., Vilimi, Z., & Antal, I. (2023) · Gels · doi:10.3390/gels9060469 · Cited by 91
Metadata
- Authors
- Fakhari, A., & Berkland, C.
- Venue
- Acta Biomaterialia
- Publisher
- Elsevier BV
- Published
- 2013-07
- Volume
- 9
- Issue
- 7
- Pages
- 7081-7092
- ISSN
- 1742-7061 (ISSN-L)
- OpenAlex
- W2024056569
- Cited by
- 518
- References
- 8
- FWCI
- 12.71
- Type
- journal article
- Language
- en
- Open access
- green
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- Fakhari, A., & Berkland, C. (2013). Applications and emerging trends of hyaluronic acid in tissue engineering, as a dermal filler and in osteoarthritis treatment. Acta Biomaterialia. https://doi.org/10.1016/j.actbio.2013.03.005
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
