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Cited by 591

The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.

The Gut Microbiota in Inflammatory Bowel Disease

Open access
Qiu, Peng, Ishimoto, Takatsugu, Fu, Lingfeng, Zhang, Jun, Zhang, Zhenyong, Liu, Yang·2022·Frontiers in Cellular and Infection Microbiology

Abstract

Epidemiological surveys indicate that the incidence of inflammatory bowel disease (IBD) is increasing rapidly with the continuous growth of the economy. A large number of studies have investigated the relationship between the genetic factors related to the susceptibility to IBD and the gut microbiota of patients by using high-throughput sequencing. IBD is considered the outcome of the interaction between host and microorganisms, including intestinal microbial factors, abnormal immune response, and a damaged intestinal mucosal barrier. The imbalance of microbial homeostasis leads to the colonization and invasion of opportunistic pathogens in the gut, which increases the risk of the host immune response and promotes the development of IBD. It is critical to identify the specific pathogens related to the pathogenesis of IBD. An in-depth understanding of various pathogenic factors is of great significance for the early detection of IBD. This review highlights the role of gut microbiota in the pathogenesis of IBD and provides a theoretical basis for the personalized approaches that modulate the gut microbiota to treat IBD.

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Metadata

Authors
Qiu, P., Ishimoto, T., Fu, L., Zhang, J., Zhang, Z., & Liu, Y.
Venue
Frontiers in Cellular and Infection Microbiology
Published
2022-02-22
Volume
12
Pages
733992-733992
ISSN
2235-2988 (ISSN-L)
OpenAlex
W4213294193
Cited by
591
References
23
FWCI
31.97
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: The Gut Microbiota in Inflammatory Bowel Disease. https://app.cochat.ai/papers/10.3389/fcimb.2022.733992
The paper
Qiu, P., Ishimoto, T., Fu, L., Zhang, J., Zhang, Z., & Liu, Y. (2022). The Gut Microbiota in Inflammatory Bowel Disease. Frontiers in Cellular and Infection Microbiology. https://doi.org/10.3389/fcimb.2022.733992

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.